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Course Overview Agenda This two-day CME program will update NPs/PAs, fellows, and junior faculty on key findings presented at the annual BMT Tandem Meeting, as well as other timely and highly relevant research and clinical care topics in the field of bone marrow transplantation. Through lecture and case-based presentations, specialists in the field will discuss current treatment challenges faced by clinicians involved in the care of both adult and pediatric transplant patients. The conference will also feature ample opportunity for interactive discussion and question/answer sessions. 7:00 am Registration Check-In and Continental Breakfast 8:00 am Welcome and Introduction 8:15 am Basic Biology of HSCT – followed by Q & A with Thomas Spitzer, MD 9:05 am Immunology/Immune Reconstitution – followed by Q & A with Kirsten Williams, MD 9:55 am BREAK This educational activity is designed for nurse practitioners, physician assistants, fellows, and junior faculty members who participate in the care of adult and pediatric bone marrow transplant patients. 10:15 am T cell Depletion – followed by Q & A with Robert Soiffer, MD 11:05 am Haploidentical and Cord Blood Transplants Update – followed by Q & A with Corey Cutler, MD, MPH, FRCPC 11:55 am LUNCH – Keynote Address: The Past, Present, and Future of Stem Cell Transplantation Jeffrey Chell, MD 12:55 pm Management of Steroid-Refractory Acute GVHD – followed by Q & A with Claudio Anasetti, MD 1. Assemble and integrate new knowledge and research findings into the evaluation and treatment of BMT patients 1:45 pm REJUVENATION SESSION 2. Develop skills that may help prevent burn-out, informing peers about challenges such as managing high acuity and emotionally demanding patients 2:00 pm Best of Tandem: Dual Sessions 3:30 pm BREAK 3:40 pm Managing Chronic GVHD and Associated LTF Issues – followed by Q & A with Jenna Goldberg, MD 4:30 pm TBA – followed by Q & A with Joseph Jacobson, MD Learning Objectives Upon completion of this course, participants will be able to: The First Regional Bone Marrow Transplantation Conference for NPs/PAs and Fellows Endorsed by the American Society for Blood and Marrow Transplantation, the Center for International Blood and Marrow Transplant Research, and the National Marrow Donor Program Hosted by Dana-Farber/Brigham and Women’s Cancer Center and Dana-Farber/Boston Children’s Cancer and Blood Disorders Center Saturday, October 25 & Sunday, October 26, 2014 Dana-Farber Cancer Institute Yawkey Center for Cancer Care, 3rd Floor Conference Center 450 Brookline Avenue Boston, MA 02215 3. Summarize current trends and describe new updates on topics such as graft versus host disease (GVHD), T-cell depleted transplantation, transfusion medicine, BMT for non-malignant disease, critical care, and haploidentical and cord blood transplantation 4. Recognize current therapeutic options for specific conditions associated with BMT, such as GVHD and infections (viral, bacterial, and fungal), and for critical care management and CAR therapies Saturday, October 25 Sunday, October 26 7:00 am Registration Check-In and Continental Breakfast 8:00 am Welcome and Introduction General Sessions 8:15 am Infections in HSCT – followed by Q & A with Sarah Page Hammond, MD 9:05 am Managing Ocular GVHD – followed by Q & A with Deborah Jacobs, MD 9:55 am BREAK 10:05 am Critical Care in HSCT – followed by Q & A with Brett Glotzbecker, MD 10:55 am Managing Relapse and Second Transplants – followed by Q & A with Yi-Bin Chen, MD 11:45 am Vaccine Trials in Transplant – followed by Q & A with David Avigan, MD 12:35 pm LUNCH 1:30 pm CAR Therapies – followed by Q & A with Craig Sauter, MD 2:20 pm Best Practices from Bench to Bedside: How Clinicians Manage the Stress of BMT – Case Presentations and Roundtable Discussion Dedicated Pediatric Sessions HARVARD MEDICAL SCHOOL 9:00 am Managing Late Effects of Pediatric HSCT – followed by Q & A with Christine Duncan, MD 10:05 am Overview of Current Pediatric Transplantation – followed by Q & A with Stella Davies, MBBS, PhD, MRCP 10:55 am Transplant for Non-Malignant Disease – followed by Q & A with Allistair Abraham, MD 11:45 am Cord Transplant for Cerebral Palsy, Hydrocephalus, and Autism – followed by Q & A with Joanne Kurtzberg, MD 3:10 pm Closing Remarks Faculty Edwin Alyea III, MD, Course Co-Director Associate Director, Adult Stem Cell Transplantation Program, Dana-Farber/Brigham and Women’s Cancer Center; Associate Professor of Medicine, Harvard Medical School Brett Glotzbecker, MD, Course Co-Director Medical Oncologist, Adult Stem Cell Transplantation Program and Lead Oncology Hospitalist, Dana-Farber/Brigham and Women’s Cancer Center; Instructor in Medicine, Harvard Medical School Deborah Yolin Raley, PA-C, Course Co-Director Director, Physician Assistant Program, Dana-Farber Cancer Institute Allistair Abraham, MD Hematologist/Oncologist, Blood and Marrow Transplantation Department, Children’s National Medical Center; Assistant Professor of Pediatrics, George Washington University School of Medicine and Health Sciences Registration and Hotel Information Registration Regional Bone Marrow Transplantation Conference for NPs/PAs and Fellows Saturday, October 25, 7:00 am – Sunday, October 26, 2014, 4:10 pm Fees (includes course materials, continental breakfast, and complimentary parking in the Dana-Farber garage): • Early-Bird (by May 15): $195 • Pre-Registration (between May 16 and October 24): $225 • On-Site Registration: $275 Claudio Anasetti, MD Chair, Blood and Marrow Transplant Department, Moffitt Cancer Center; Professor of Oncology, University of South Florida David Avigan, MD Director, Hematologic Malignancies/Bone Marrow Transplant Program, Beth Israel Deaconess Medical Center; Associate Professor of Medicine, Harvard Medical School Jeffrey Chell, MD Chief Executive Officer, National Marrow Donor Program; Executive Director, Center for International Blood and Marrow Transplant Research Dana-Farber Cancer Institute Yawkey Center for Cancer Care – 3rd Floor Conference Center 450 Brookline Avenue Boston, MA About the Dana-Farber/Brigham and Women’s Cancer Center Adult Stem Cell Transplantation Program Since its inception, the Adult Stem Cell Transplantation Program has performed more than 7,000 transplants—including for older adults and others with complex cases—and stands as a world leader in providing excellent clinical care and cutting-edge scientific research, resulting in better patient outcomes. For more information, please visit www.dfbwcc.org/BMT or call 877-DFCI-BWH (332-4294). Please register online by visiting www.regonline.com/BMT. Should you have food allergies; require accommodations such as an ASL interpreter, materials in alternative format, or wheelchair access; or have any additional questions, please e-mail [email protected] or call 617-582-8487. Yi-Bin Chen, MD Director of Clinical Research, Bone Marrow Transplant Program, Massachusetts General Hospital Cancer Center; Assistant Professor of Medicine, Harvard Medical School Corey Cutler, MD, MPH, FRCPC Medical Oncologist, Adult Stem Cell Transplantation Program, Dana-Farber/Brigham and Women’s Cancer Center; Associate Professor of Medicine, Harvard Medical School Stella Davies, MBBS, PhD, MRCP Director, Bone Marrow Transplantation and Immune Deficiency Division, Cincinnati Children’s Hospital Medical Center; Professor of Pediatrics, University of Cincinnati Medical School Christine Duncan, MD Hematologist/Oncologist, Pediatric Stem Cell Transplantation Program, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center; Assistant Professor of Pediatrics, Harvard Medical School Jenna Goldberg, MD Hematologist/Oncologist, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center; Instructor of Medicine, Weill Cornell Medical College Hotel The Residence Inn by Marriott Boston Back Bay/Fenway – located at 125 Brookline Avenue in Boston, within walking distance of the Yawkey Center for Cancer Care – is pleased to offer a discounted room rate of $279 per night to conference attendees. This rate applies to a Studio Suite room and is applicable from the evening of Friday, October 24 through check-out on Monday, October 27. To reserve your room, please call 800-331-3131 and be sure to request the special rate for the Dana-Farber Stem Cell Transplant Room Block. About the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center Pediatric Stem Cell Transplantation Program Forming one of the largest and most experienced programs in the United States— performing more than 90 transplants every year—Dana-Farber/Boston Children’s team includes both physicians and scientists who are leaders in the field of pediatric stem cell transplantation, as well as nationally known pediatric subspecialists. For more information, please visit www.danafarberbostonchildrens.org or call 855-320-2094. Sarah Page Hammond, MD Infectious Disease Specialist, Hematologic Oncology Treatment Center, Dana-Farber/Brigham and Women’s Cancer Center; Instructor in Medicine, Harvard Medical School Deborah Jacobs, MD Ophthalmologist, Massachusetts Eye and Ear Infirmary; Assistant Professor of Ophthalmology, Harvard Medical School Joseph Jacobson, MD Chief Quality Officer, Dana-Farber Cancer Institute; Associate Professor of Medicine, Harvard Medical School Joanne Kurtzberg, MD Director, Pediatric Blood and Marrow Transplant Program; Chief Scientific and Medical Officer, Robertson Clinical and Translational Cell Therapy Program; Director, Carolinas Cord Blood Bank; and Co-Director, Stem Cell Laboratory, Duke University School of Medicine Craig Sauter, MD Hematologist/Oncologist, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center; Instructor of Medicine, Weill Cornell Medical College Robert J. Soiffer, MD Chief, Hematologic Malignancies Division and Co-Chief, Adult Stem Cell Transplantation Program, Dana-Farber/Brigham and Women’s Cancer Center; Professor of Medicine, Harvard Medical School Thomas Spitzer, MD Director, Bone Marrow Transplant Program, Massachusetts General Hospital Cancer Center; Professor of Medicine, Harvard Medical School Kirsten Williams, MD Hematologist/Oncologist, Blood and Marrow Transplantation Department, Children’s National Medical Center; Assistant Professor of Pediatrics, George Washington University School of Medicine and Health Sciences Accreditation ANCC recognizes CME as equivalent to CEU hours for RNs and NPs. CME Credits: The Harvard Medical School is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Harvard Medical School designates this live activity for a maximum of 15.5 AMA PRA Category 1 Credits™. Physicians should claim only credit commensurate with the extent of their participation in the activity. ACGME COMPETENCIES: This course is designed to enhance one or more of the following Accreditation Council of Graduate Medical Education competencies: Patient care • Medical knowledge • Practice-based learning and improvement • Systems-based practice. Harvard Medical School (HMS) adheres to all ACCME Essential Areas, Standards, and Policies. It is HMS’s policy that those who have influenced the content of a CME activity (e.g. planners, faculty, authors, reviewers, and others) disclose all relevant financial relationships with commercial entities so that HMS may identify and resolve any conflicts of interest prior to the activity. These disclosures will be provided in the activity materials along with disclosure of any commercial support received for the activity. Additionally, faculty members have been instructed to disclose any limitations of data and unlabeled or investigational uses of products during their presentations.