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Transcript
3rd Ringberg Meeting on Structural Biology with FELs
Wednesday, February 10th, 2016
> 15:00
Coffee, cake, Garden room
Chair: Adrian Mancuso
Welcome
16:20
Ilme Schlichting
16:30
Garth Williams
Early successes in the single particle imaging initiative at LCLS
17:00
Kartik Ayyer
Disorder and crystallographic resolution: What goes on beyond the last Bragg peak
17:30
Beata Ziaja-Motyka
Coherent diffraction imaging of single macromolecules at atomic resolution – challenges for theory
18:00
Sébastien Boutet
XFEL-induced structural changes to water and protein crystals using two-color pulses
18:30
Dinner
Thursday, February 11th, 2016
Chair: Loes Kroon-Batenburg
9:00
Nicolas Coquelle
NanoPeakCell: sorting the good from the bad... At any X-Ray source
9:30
Helen Ginn
Development of methods in XFEL data analysis
Nicholas Sauter
Large Scale Parameter Refinement for SFX Data Processing
Coffee break
10:00
10:30
Chair: Alke Meents
11:00
Darren Sherrell
The Highs and Lows of Fixed Target Arrays
11:30
Philip Rödig
ROAD-RUNNER: High Speed Fixed Target Serial Crystallography at Ultra Low Background
12:00
Lutz Vogeley
In Situ Serial Crystallography of Soluble and Membrane Proteins in the Lipid Cubic Phase
12:30
12:40
Group photo (depending on weather)
Lunch
1
Chair: Bruce Doak
14:00
Dominik Oberthür
14:30
Allen Orville
Optimizing sample delivery for minimal sample consumption and time-resolved SFX
Phytochromes and Acoustic Injectors as R&D Drivers of Time-Resolved Structural Biology
15:00
Martin Trebbin
Considerations for time-resolved rapid mixing experiments at XFELs
Coffee break
15:30
16:00
Robert Dods
Chair: Joachim Schulz
Time-resolved Serial Femtosecond Crystallography of Photosynthetic Reaction Center
16:30
Eriko Nango
Light-activated intermediate structures of bacteriorhodopsin determined by time-resolved SFX
17:00
Jason Tenboer
Reaction dynamics in proteins
17:30
Thomas Barends
Ultrafast time-resolved SFX measurements on heme proteins
18:00
Tour of the castle
Dinner
18:45
Chair: Janet Smith
20:00
Martin Weik
Time-resolved serial femtosecond crystallography on a photoswitchable fluorescent protein
20:30
Stefan Raunser
Advantages of single particle electron cryo microscopy
Friday February 12th, 2016
Chair: Oliver Bunk
9:00
Kenta Okamoto
Large and giant viruses in the beam of an electron and an X-ray laser.
9:30
Jan Pieter Abrahams
Structure determination from incomplete electron diffraction data of a single 3D lysozyme
nanocrystal
Current challenges and Successes in MicroED
10:00
10:30
Francis Reyes
Coffee break
2
Chair: Thomas White
11:00
Keitaro Yamashita
11:30
Jacques Colletier
Experimental phasing with serial crystallography using heavy atom derivatives
A potent binary mosquito larvicide revealed by de novo phasing with an X-ray free-electron laser
12:00
Karol Nass
On phasing SFX data
12:30
Lunch
14:00
Discussion rounds / Hiking
18:30
Conference Dinner
Chair: Ilme Schlichting
20:00
Yota Fukuda
20:30
Meeting slot
Saturday, February 13th, 2016
Chair: Edgar Weckert
9:00
Yun-Xing Wang
9:30
Yota Fukuda
10:00
10:30
Mengning Liang
Jean-Nicolas Longchamp
Challenges in RNA structural biology and a hope offered from XFEL
Insights from damage-free X-ray crystallography: revisiting the reaction mechanism of copper
nitrite reductases
Analysis of crystalline fiber data
Enabling structural biology at the truly single molecule level by means of coherent low-energy
electron microscopy
Departure, lunch packages if desired
3