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Managing blood glucose levels in people with Diabetes Mellitus: The
MiniMed Paradigm Veo System (and other alternative technologies
identified in scoping)
Diabetes mellitus is a chronic metabolic disorder which causes a person’s
blood glucose to become too high. To prevent this, insulin is often
administered to reduce the blood glucose level but sometimes, this can cause
blood glucose levels to become too low and lead to hypoglycaemia. Achieving
good blood glucose control reduces the risk of diabetes-related complications
such as diabetic eye and kidney diseases and diabetic-related cardiovascular
events. The MiniMed Paradigm Veo System is an integrated continuous
glucose monitoring and insulin pump system intended for use as an aid in
managing blood glucose levels in people with diabetes. It produces alerts if
glucose levels become too high or low, if levels are rapidly changing, or if the
system predicts glucose levels will be too high or too low in the near future.
The system can also suspend insulin delivery automatically if there is no
response to a low glucose warning. This could be beneficial in reducing the
incidence of nocturnal hypoglycaemia and associated anxiety. Other potential
patient benefits of the technology include improved glucose control resulting
in fewer diabetes-related complications, improved quality of life and easier
adherence to treatment. Potential healthcare system benefits of the
technology include cost and resource savings associated with a reduction in
hospital admissions due to diabetes-related complications, and achieving
optimum therapy more quickly. The NICE Diagnostics Assessment
Programme will assess the clinical and cost-effectiveness of the MiniMed
Paradigm Veo System (and other alternative technologies identified during
scoping) in order to make recommendations on its use in the NHS.