Download Slides in pps format

E-Seminar Protocols
As a courtesy to others, please mute
your phone line while listening
Press *6 to mute (listen)
Press #6 to un-mute (ask a question)
1
One-Minute NMR
2007 demo tour
•
•
•
•
•
University of Buffalo: Buffalo, NY; January 8
TriMR Regional Meeting: Research Triangle Pk, NC; Feb 15-16
Southwest Regional Demonstration, San Diego, CA; Mar 27 (anticip)
ENC: Daytona Beach, FL; April 22 – 26 (anticip)
Schedule a live demo in your area! Call Protasis for details.
6 March, 2007
Presented by Tim Peck
2
One-Minute NMR
Winter 2006-07
3
Metabonomics Research Day
University of Buffalo Amherst
January 8, 2007
Natural Sciences Complex
Center for Tomorrow
4
Metabonomics Research Day
University of Buffalo Amherst
Morning Session
Metabonomics and Top-Down
Systems Biology:
From Personalized Healthcare to
Molecular Epidemiology
Plenary Speaker:
Professor Jeremy Nicholson
Effects of Ligand and
Ability to Lower Blood
Glucose on Global Gene
Expression in STZDiabetic Rats Treated with
Oxovanadium Compounds
1H-NMR Metabonomics for
Detecting Epithelial
Ovarian Cancer
Dr. Kunle Odunsi
Dept of Gynecologic Oncology
RPCI
Prof. Gail Willsky
Dept of Biochemistry
Univ. Buffalo
Prof. Frank Schroeder
Cornell University and Harvard Medical School
The virtue of the impure: chemical biology revealed
by direct NMR
5
Metabonomics Research Day
University of Buffalo Amherst
Afternoon Roundtable
Session 1: Scientific Infrastructure for
Metabonomics – Instrumentation,
Software and Databases
Dinesh Sukumaran, Ph.D.
Director, Magnetic Resonance Center
Department of Chemistry, U. Buffalo
Session 2: Synergy of NMR
Session 3: Metabonomics –
Spectroscopy and Mass Spectrometry in
Metabonomics
Related Research
Prof. Thomas Szyperski
Dept. of Chemistry and Biochemistry
U. Buffalo
Session 4: Metabonomics in an
‘ohmics’ world
Prof. George DeTitta
Dept. Structural Biology
U. Buffalo
Prof. Jeremy Nicholson
Dept. of Biological Chemistry
Imperial College
6
TriMR Regional Meeting
Research Triangle Park
Feb. 15, 2007
• Hosted at GlaxoSmithKline
Vs.
7
TriMR Regional Meeting
Research Triangle Park
Feb. 15, 2007
8
One-Minute NMR:
Integrated System Approach
Well Plate or
Vial Tray
6- or 12-Tray
Capacity
for Vials
or Trays
Sample
Return
Discovery
Tower
Web-based
Software
CapNMR Probe
5- or 10-µL
Multi-Solvent
Wash Station
• Microliter precision
• 0.1 mm xyz positioning
On-Board
Instrument
Server
Accident-Free
Syringe
and Needle
Well Plate or Vial
Sample Format
9
Automation: Accident-Free Syringe and Needle
Carriage comes to rest
before needle is lowered
10
Automation: Solvent Conditioner
Solvent Bottles
Under Positive Pressure
Solvent Conditioner
Vacuum Pump
Result: Dry, Degassed, Protected
Deuterated Solvent
11
Integrated
Approach
12
MicroFlow NMR Literature
www.microNMR.com
13
Your MicroFlow NMR Product Source
www.protasis.com
14