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B3 2 Summary Transporting substances around the body Chapter review AQA Science © Nelson Thornes Ltd 2006 1 B3 2 Summary How does your circulatory system work? • Three elements: blood vessels, heart and blood. • Three types of blood vessels: veins, arteries and capillaries. • Heart acts as a pump, moving blood around the body. • Double circulation: – heart to lungs to heart. – heart to body to heart. AQA Science © Nelson Thornes Ltd 2006 2 B3 2 Summary How does your blood transport substances? • Blood consists of plasma, red blood cells, white blood cells and platelets. • Plasma is a yellow liquid. • Plasma transports all of the blood cells, carbon dioxide, urea, soluble products of digestion, e.g. glucose. • Red blood cells carry oxygen. Photo: Photodisc 59 (NT) AQA Science © Nelson Thornes Ltd 2006 3 B3 2 Summary How are red blood cells adapted to carry oxygen? • Large numbers – five million per 1 mm3. • Biconcave discs for increased surface area. • Packed full of haemoglobin – red pigment that can carry oxygen. • No nucleus – makes more space for haemoglobin. AQA Science © Nelson Thornes Ltd 2006 4 B3 2 Summary How does exercise affect your body? • Muscles use oxygen for aerobic respiration, to provide energy as glucose is broken down. • When you exercise, muscles work – they need more oxygen. • Heart rate increases. • You breathe more deeply. • More oxygen in, more carbon dioxide out. AQA Science © Nelson Thornes Ltd 2006 5 B3 2 Summary Higher What is an oxygen debt? • Lots of exercise causes muscle fatigue. • The body switches to anaerobic respiration – not as efficient, so it gives less energy. • Lactic acid is produced. • When exercise is over, the body has to break down lactic acid Photo: Photodisc 51 (NT) using oxygen. • Demand for oxygen stays high until lactic acid is all gone – oxygen needed is oxygen debt. AQA Science © Nelson Thornes Ltd 2006 6 B3 2 Summary Why are your kidneys so important? • Important for homeostasis. • Remove urea from blood. • Remove excess water from blood or conserve water. • Remove excess mineral ions from blood or conserve mineral ions. • Filter blood and reabsorb everything needed, e.g. glucose, by selective reabsorption. • Produce urine. AQA Science © Nelson Thornes Ltd 2006 7 B3 2 Summary What is kidney dialysis? • Kidney failure means death, unless the function of the kidneys is replaced. • Dialysis replaces kidney function – filters and cleans blood. • Depends on diffusion along concentration gradients from blood to dialysis fluid. Photo: SPL BSIP/Beranger AQA Science © Nelson Thornes Ltd 2006 8 B3 2 Summary What is a kidney transplant? • Failed kidneys replaced by single healthy kidney from donor. • Donor usually dead, but may be living. • To prevent rejection by the immune system: – The kidney is as close a tissue match as possible. – The recipient takes immunosuppressant drugs for life. AQA Science © Nelson Thornes Ltd 2006 9 B3 2 Summary Which is best – dialysis or transplant? Dialysis: • Machines usually available. • No problems with tissue matching. • Has to happen at least twice a week for life. • Expensive long-term. • Have to watch diet. Transplant: • No special diet. • No sessions of dialysis. • Relatively inexpensive, particularly after surgery. • Need donor, often not available. • Need tissue match. • Have to take immunosuppressant drugs for life. • Surgery every ten years or so. AQA Science © Nelson Thornes Ltd 2006 10