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Jorge Benitez Ph.D. Affiliation: Morehouse School of Medicine Title: Associate Professor, Dept. of MBI Address: Contact: Email: [email protected] Telephone: 404-752-1580 Publications 1. Wang H, Ayala JC, Silva AJ, Benitez JA. The histone-like nucleoid structuring protein PubMed (H-NS) is a repressor of Vibrio cholerae exopolysaccharide biosynthesis (vps) genes. Appl Environ Microbiol. 2012 Apr; 78(7):2482-8. 2. Wang H, Ayala JC, Benitez JA, Silva AJ. Interaction of the histone-like nucleoid PubMed structuring protein and the general stress response regulator RpoS at Vibrio cholerae promoters that regulate motility and hemagglutinin/protease expression. J Bacteriol. 2012 Mar; 194(5):1205-15. 3. Wang H, Wu JH, Ayala JC, Benitez JA, Silva AJ. Interplay among cyclic diguanylate, PubMed HapR, and the general stress response regulator (RpoS) in the regulation of Vibrio cholerae hemagglutinin/protease. J Bacteriol. 2011 Dec; 193(23):6529-38. 4. Rasmussen L, White EL, Pathak A, Ayala JC, Wang H, Wu JH, Benitez JA, Silva AJ. A PubMed high-throughput screening assay for inhibitors of bacterial motility identifies a novel inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio cholerae. Antimicrob Agents Chemother. 2011 Sep; 55(9):4134-43. 5. Silva AJ, Benitez JA, Wu JH. Attenuation of bacterial virulence by quorum sensing- PubMed regulated lysis. J Biotechnol. 2010 Oct 01; 150(1):22-30. 6. Sultan SZ, Silva AJ, Benitez JA. The PhoB regulatory system modulates biofilm PubMed formation and stress response in El Tor biotype Vibrio cholerae. FEMS Microbiol Lett. 2010 Jan; 302(1):22-31. 7. Liang W, Sultan SZ, Silva AJ, Benitez JA. Cyclic AMP post-transcriptionally regulates PubMed the biosynthesis of a major bacterial autoinducer to modulate the cell density required to activate quorum sensing. FEBS Lett. 2008 Nov 12; 582(27):3744-50. 8. Silva AJ, Sultan SZ, Liang W, Benitez JA. Role of the histone-like nucleoid structuring PubMed protein in the regulation of rpoS and RpoS-dependent genes in Vibrio cholerae. J Bacteriol. 2008 Nov; 190(22):7335-45. 9. Silva AJ, Eko FO, Benitez JA. Exploiting cholera vaccines as a versatile antigen PubMed delivery platform. Biotechnol Lett. 2008 Apr; 30(4):571-9. 10. Liang W, Silva AJ, Benitez JA. The cyclic AMP receptor protein modulates colonial PubMed morphology in Vibrio cholerae. Appl Environ Microbiol. 2007 Nov; 73(22):7482-7. 11. Liang W, Pascual-Montano A, Silva AJ, Benitez JA. The cyclic AMP receptor protein PubMed modulates quorum sensing, motility and multiple genes that affect intestinal colonization in Vibrio cholerae. Microbiology. 2007 Sep; 153(Pt 9):2964-75. 12. Hazra A, Silva AJ, Benitez JA. Expression of foreign proteins in a Vibrio cholerae PubMed vaccine strain using the stationary phase hemagglutinin/protease promoter. Biotechnol Lett. 2007 Jul; 29(7):1093-7. 13. Jahid IK, Silva AJ, Benitez JA. Polyphosphate stores enhance the ability of Vibrio PubMed cholerae to overcome environmental stresses in a low-phosphate environment. Appl Environ Microbiol. 2006 Nov; 72(11):7043-9. 14. Silva AJ, Leitch GJ, Camilli A, Benitez JA. Contribution of hemagglutinin/protease and PubMed motility to the pathogenesis of El Tor biotype cholera. Infect Immun. 2006 Apr; 74(4):2072-9. 15. Silva AJ, Benitez JA. A Vibrio cholerae relaxed (relA) mutant expresses major PubMed virulence factors, exhibits biofilm formation and motility, and colonizes the suckling mouse intestine. J Bacteriol. 2006 Jan; 188(2):794-800. 16. Silva AJ, Benitez JA. Th1-type immune response to a Coccidioides immitis antigen PubMed delivered by an attenuated strain of the non-invasive enteropathogen Vibrio cholerae. FEMS Immunol Med Microbiol. 2005 Mar 01; 43(3):393-8. 17. Silva AJ, Benitez JA. Transcriptional regulation of Vibrio cholerae PubMed hemagglutinin/protease by the cyclic AMP receptor protein and RpoS. J Bacteriol. 2004 Oct; 186(19):6374-82. 18. Silva AJ, Mohan A, Benitez JA. Cholera vaccine candidate 638: intranasal PubMed immunogenicity and expression of a foreign antigen from the pulmonary pathogen Coccidioides immitis. Vaccine. 2003 Dec 01; 21(32):4715-21. 19. Silva AJ, Pham K, Benitez JA. Haemagglutinin/protease expression and mucin gel PubMed penetration in El Tor biotype Vibrio cholerae. Microbiology. 2003 Jul; 149(Pt 7):1883-91. THANK YOU FOR USING THE RTRN RESEARCH COLLABORATION AND PROFESSIONAL NETWORKING SERVICE. RTRN Data Coordinating Center Mississippi e-Center @ Jackson State University 1230 Raymond Road, Box 1800, Jackson, Mississippi 39204 Phone: 601-979-0332, Fax: 601-979-0338, e-mail: [email protected]