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Jorge Benitez Ph.D.
Affiliation:
Morehouse School of Medicine
Title: Associate Professor, Dept. of MBI
Address:
Contact:
Email: [email protected]
Telephone: 404-752-1580
Publications
1.
Wang H, Ayala JC, Silva AJ, Benitez JA. The histone-like nucleoid structuring protein PubMed
(H-NS) is a repressor of Vibrio cholerae exopolysaccharide biosynthesis (vps) genes.
Appl Environ Microbiol. 2012 Apr; 78(7):2482-8.
2.
Wang H, Ayala JC, Benitez JA, Silva AJ. Interaction of the histone-like nucleoid PubMed
structuring protein and the general stress response regulator RpoS at Vibrio
cholerae promoters that regulate motility and hemagglutinin/protease expression. J
Bacteriol. 2012 Mar; 194(5):1205-15.
3.
Wang H, Wu JH, Ayala JC, Benitez JA, Silva AJ. Interplay among cyclic diguanylate, PubMed
HapR, and the general stress response regulator (RpoS) in the regulation of Vibrio
cholerae hemagglutinin/protease. J Bacteriol. 2011 Dec; 193(23):6529-38.
4.
Rasmussen L, White EL, Pathak A, Ayala JC, Wang H, Wu JH, Benitez JA, Silva AJ. A PubMed
high-throughput screening assay for inhibitors of bacterial motility identifies a novel
inhibitor of the Na+-driven flagellar motor and virulence gene expression in Vibrio
cholerae. Antimicrob Agents Chemother. 2011 Sep; 55(9):4134-43.
5.
Silva AJ, Benitez JA, Wu JH. Attenuation of bacterial virulence by quorum sensing- PubMed
regulated lysis. J Biotechnol. 2010 Oct 01; 150(1):22-30.
6.
Sultan SZ, Silva AJ, Benitez JA. The PhoB regulatory system modulates biofilm PubMed
formation and stress response in El Tor biotype Vibrio cholerae. FEMS Microbiol Lett.
2010 Jan; 302(1):22-31.
7.
Liang W, Sultan SZ, Silva AJ, Benitez JA. Cyclic AMP post-transcriptionally regulates PubMed
the biosynthesis of a major bacterial autoinducer to modulate the cell density
required to activate quorum sensing. FEBS Lett. 2008 Nov 12; 582(27):3744-50.
8.
Silva AJ, Sultan SZ, Liang W, Benitez JA. Role of the histone-like nucleoid structuring PubMed
protein in the regulation of rpoS and RpoS-dependent genes in Vibrio cholerae. J
Bacteriol. 2008 Nov; 190(22):7335-45.
9.
Silva AJ, Eko FO, Benitez JA. Exploiting cholera vaccines as a versatile antigen PubMed
delivery platform. Biotechnol Lett. 2008 Apr; 30(4):571-9.
10. Liang W, Silva AJ, Benitez JA. The cyclic AMP receptor protein modulates colonial PubMed
morphology in Vibrio cholerae. Appl Environ Microbiol. 2007 Nov; 73(22):7482-7.
11. Liang W, Pascual-Montano A, Silva AJ, Benitez JA. The cyclic AMP receptor protein PubMed
modulates quorum sensing, motility and multiple genes that affect intestinal
colonization in Vibrio cholerae. Microbiology. 2007 Sep; 153(Pt 9):2964-75.
12. Hazra A, Silva AJ, Benitez JA. Expression of foreign proteins in a Vibrio cholerae PubMed
vaccine strain using the stationary phase hemagglutinin/protease promoter.
Biotechnol Lett. 2007 Jul; 29(7):1093-7.
13. Jahid IK, Silva AJ, Benitez JA. Polyphosphate stores enhance the ability of Vibrio PubMed
cholerae to overcome environmental stresses in a low-phosphate environment. Appl
Environ Microbiol. 2006 Nov; 72(11):7043-9.
14. Silva AJ, Leitch GJ, Camilli A, Benitez JA. Contribution of hemagglutinin/protease and PubMed
motility to the pathogenesis of El Tor biotype cholera. Infect Immun. 2006 Apr;
74(4):2072-9.
15. Silva AJ, Benitez JA. A Vibrio cholerae relaxed (relA) mutant expresses major PubMed
virulence factors, exhibits biofilm formation and motility, and colonizes the suckling
mouse intestine. J Bacteriol. 2006 Jan; 188(2):794-800.
16. Silva AJ, Benitez JA. Th1-type immune response to a Coccidioides immitis antigen PubMed
delivered by an attenuated strain of the non-invasive enteropathogen Vibrio
cholerae. FEMS Immunol Med Microbiol. 2005 Mar 01; 43(3):393-8.
17. Silva
AJ, Benitez JA. Transcriptional regulation of Vibrio cholerae PubMed
hemagglutinin/protease by the cyclic AMP receptor protein and RpoS. J Bacteriol.
2004 Oct; 186(19):6374-82.
18. Silva AJ, Mohan A, Benitez JA. Cholera vaccine candidate 638: intranasal PubMed
immunogenicity and expression of a foreign antigen from the pulmonary pathogen
Coccidioides immitis. Vaccine. 2003 Dec 01; 21(32):4715-21.
19. Silva AJ, Pham K, Benitez JA. Haemagglutinin/protease expression and mucin gel PubMed
penetration in El Tor biotype Vibrio cholerae. Microbiology. 2003 Jul; 149(Pt
7):1883-91.
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