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Chapter 14 Noncommunicable Diseases Lesson 14.1 Noncommunicable Diseases: What You Should Know Lesson 14.2 Diseases of the Blood Vessels and Heart Lesson 14.3 Cancer: Cells Out of Control Lesson 14.4 Diabetes, Allergies, Asthma, and Arthritis Lesson 14.1 Noncommunicable Diseases: What You Should Know Warm-Up Noncommunicable Diseases What are some risk factors related to developing heart disease and cancer? What are some steps you can take to avoid or manage these risk factors? thinkstock.com/iStock/sjenner13 Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Noncommunicable Disease and Homeostasis • Noncommunicable diseases are those that cannot be spread through person-to-person contact • When the body maintains homeostasis, the body is healthy • If the body departs from homeostasis, it will enter a state of disease shutterstock.com/Andresr Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Risk Factors • Lifestyle choices and the environment are key areas that indicate a person’s risk factor for certain diseases • Scientists have identified genes, especially mutated genes, that increase the risk for developing certain diseases Click here for the Unit 5 video, “‘No Big Deal,’ or Is It?” shutterstock.com/Kenneth Man Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Disease Characteristics • Certain characteristics are associated with noncommunicable diseases • Acute diseases occur suddenly and resolve fairly quickly • Chronic illnesses may not heal for years and can cause permanent disability or health complications shutterstock.com/Photographee.eu A cold is an example of an acute disease. Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Disease Characteristics • A prognosis is the probable outcome of a disease, including the the duration and severity • A relapse is a recurrence of a disease • A complication is a new problem or related disease that arises shutterstock.com/Monkey Business Images Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Think Further Myth or Fact? Having a disease be in remission is the same as being cured of that disease. MYTH – Fact: Remission is a time without signs and symptoms of a disease, but the disease may still be present. – Fact: Remission may last for weeks, years, or indefinitely. Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Diagnosing Diseases • A diagnosis identifies the type of disease a person has • A diagnosis may involve – Physical exam – Personal and family history – Lab tests • Once a diagnosis is clear, treatment can begin shutterstock.com/Monkey Business Images Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Critical Thinking Diagnosing Disease Why is knowing about a person’s family history important for diagnosing diseases? What are some noncommunicable diseases that members of your family have had? Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Lesson 14.2 Diseases of the Blood Vessels and Heart Profile of Healthy Blood Vessels • Blood vessels are narrow tubes that transport oxygen, blood, and nutrients throughout the body – Arteries carry blood from the heart to the capillaries – Capillaries deliver oxygen and nutrients to body tissues – Veins carry blood from the capillaries back to the heart Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Diseases of the Blood Vessels • Arteriosclerosis causes arterial walls to thicken, harden, and become inflexible. Atherosclerosis describes fatty deposits in arterial walls • These fatty deposits may block blood flow to vital organs Click here for the “Progression of Atherosclerosis” animation Body Scientific International, LLC. Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Hypertension • Blood pressure is the force that blood exerts against the walls of arteries • High blood pressure is called hypertension • Hypertension causes problems in blood vessels and organs and sets the stage for a heart attack or stroke shutterstock.com/Tyler Olson Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Think Further What are the two parts of a blood pressure measurement called? What does each measure? – Systolic pressure is the blood pressure that exists when the heart muscle is contracted. – Diastolic pressure records the blood pressure when the heart muscle is relaxed between contractions. Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Stroke Obesity and smoking are lifestyle risk factors for stroke. shutterstock.com/Monkey Business Images • Stroke is a disease that occurs when the blood flow to a part of the brain is interrupted, injuring brain cells • An ischemic stroke is the most common type • A hemorrhagic stroke is less common Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Profile of a Healthy Heart • The heart requires its own continuous supply of oxygen and nutrients • These are delivered by blood vessels called coronary arteries • These blood vessels are branches of the largest artery in the body, the aorta Body Scientific International, LLC. Click here for the “Blood Flow through the Heart” animation Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Diseases of the Heart • Coronary artery disease occurs when the coronary arteries become narrow or blocked and reduce or stop blood flow to the heart muscle • In congestive heart failure, the heart weakens due to strain and becomes unable to pump blood effectively • Disorders of heart rhythm are called arrhythmias and can arise from abnormal communication within the heart muscle • Several diseases can affect the heart valves and impact their performance Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Diagnosis and Treatment of Heart Disease • Several tests can be done to help determine the nature of a heart disease • Stents and bypass surgery can be used to treat blocked arteries • Coronary artery disease can also be treated with medicine shutterstock.com/Alexander Raths Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Lesson 14.3 Cancer: Cells out of Control Characteristics of Cancer • Cancer is a disease characterized by a mass of abnormally growing cells that spread and cause illness • Benign tumors do not invade nearby tissue • Malignant tumors invade the normal tissues and can metastasize shutterstock.com/Designua Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Risk Factors for Cancer • Genetics is related to cancer • A cell with faulty protooncogenes divides much more rapidly than surrounding cells • A cell with faulty tumorsuppressor genes cannot stop cell division shutterstock.com/Nuno Andre Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Risk Factors for Cancer • Exposure to carcinogens increases the risk of cancer • Certain carcinogens cause mutations in genes, leading to cancer – Asbestos – Ultraviolet radiation – Tobacco smoke • Infectious microorganisms are linked to certain cancers – Human papillomavirus (HPV) – Hepatitis B virus and hepatitis C virus – HIV shutterstock.com/DVARG Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Critical Thinking Lifestyle Choices What are some lifestyle choices people make that affect their risk of getting cancer? thinkstock.com/Stockbyte/Stockbyte Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Common Cancers • Skin cancer—caused by ultraviolet (UV) light that damages genes and triggers cancerous changes in skin cells • Lung cancer—typically begins in the lungs and spreads to other organs • Breast cancer—risk factors include genetics, age, and lifestyle choices • Colon and rectal cancer—typically appears in people 50 years of age or older Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Cancer Treatment • A combination of treatments is often more effective than any one treatment alone • Possible treatments include – – – – – shutterstock.com/wavebreakmedia Surgery Chemotherapy Hormone therapy Immune therapy Radiation therapy Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Think Further Many cancer patients are treated with chemotherapy. What are some of the possible side effects of chemotherapy? – – – – – Weight loss Hair loss Nausea and diminished diet Lowered resistance to infections Bleeding Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Lesson 14.4 Diabetes, Allergies, Asthma, and Arthritis Diabetes • Diabetes mellitus is a disease resulting from the body’s inability to regulate glucose (sugar) • Type 1 diabetes mellitus (juvenile-onset) can be treated with insulin, strict diet management, and regular physical activity • Treatment for type 2 diabetes mellitus (adultonset) includes modifying the diet, managing weight, and taking medications • Related long-term problems may include vision loss, kidney failure, and impaired nerve function Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Think Further What are some risk factors for type 2 diabetes? – – – – – – A family history of diabetes Advanced age Obesity A physically inactive lifestyle High blood pressure High cholesterol Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Allergies • An allergy is an abnormal, destructive immune response with effects that can range from annoying to deadly • An allergy is triggered by substances called allergens, such as dust or pollen • Some allergies are restricted to specific organs, while other allergies affect the entire body Click here for the “Allergic Reactions” animation Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Asthma • Asthma is a chronic disease of the respiratory system in which the air passages constrict • The environment and heredity play a role in the development of asthma • Asthma cannot be cured, but medications can reduce the number and severity of attacks shutterstock.com/bikeriderlondon Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Arthritis • Arthritis means inflammation of the joints • Treatments include antiinflammatory medicine, pain relievers, and mild exercise • Osteoarthritis is caused by the wearing down of cartilage that normally pads the surfaces of bones shutterstock.com/Catalin Petolea Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Rheumatoid Arthritis • Rheumatoid arthritis is an autoimmune disease • It causes the body’s immune system to attack the joints • It occurs in adults of all ages and affects many joints, the eyes, and the heart shutterstock.com/Rob Marmion Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website. Think Further What is gout? What may cause gout? – Gout is a type of arthritis that occurs in some aging adults. – Gout can be caused by diets that are rich in purines (found in red meat, anchovies, and asparagus). – Gout can also be triggered by consuming alcoholic beverages. Copyright Goodheart-Willcox Co., Inc. May not be posted to a publicly accessible website.