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Waste Excretion and Internal Equilibrium Chapter 12.1 (Part A) Pgs. 378 - 380 A look at your kidneys Kidneys are bean-shaped organs (two) Each are about the size of your fist They are located in the middle of your back, just below your rib cage, on either side of your spine. They receive a huge amount -- 20 percent -- of the blood pumped by the heart What do your kidneys do? The large blood supply to your kidneys enables them to do the following tasks: 1. Regulate the composition of your blood keep the concentrations of various ions and other important substances constant keep the volume of water in your body constant remove wastes from your body (urea, ammonia, drugs, toxic substances) keep the acid/base concentration of your blood constant What do your kidneys do?..cont 2. Help regulate your blood pressure 3. Maintain your body's calcium levels Your kidneys receive blood from the renal artery, process it, return the processed blood to the body through the renal vein and remove the wastes and other unwanted substances in the urine. ureters Urine flows from the kidneys through the ureters to the bladder. Entry point of ureter In the bladder, the urine is stored until it urethra Urinary sphincters is excreted from the body through the urethra. Urethral oriface Deamination – removal of an amino group from an organic compound Urea – nitrogen waste formed from two molecules of ammonia and one molecule of carbon dioxide Uric acid – a waste product formed from the breakdown of nucleic acids Inside the Kidney A. B. C. D. E. If you were to cut a kidney in half, you would see the following parts: renal capsule - a thin, outer membrane that helps protect the kidney cortex – the outer layer of the kidney medulla – the area inside of the cortex renal pelvis – the hollow area where the kidney joins the ureter ureter – a tube that conducts urine from the kidney to the bladder Label this Kidney! From the descriptions on the parts given, Renal artery label this kidney Renal medulla Renal cortex Renal vein ureter Renal pelvis Further inside your Kidneys If you look closely at the cortex and medulla, you can see many tiny, tubular structures In each kidney, there are one million of these structures, called nephrons The nephron is a long thin tube that is closed at one end, has two twisted regions interspaced with a long hair-pin loop, ends in a long straight portion and is surrounded by capillaries. Parts of the Nephron Bowman's capsule – a cup-like structure that surrounds the glomerulus Proximal tubule – the section of the nephron joining the Bowman’s capsule with the loop of Henle. Loop of Henle – the section of the tubule that carries filtrate from the proximal tubule to the distal tubule Parts of the Nephron cont . . Distal tubule – conducts urine from the loop of Henle to the collecting duct Collecting duct – a tube that carries urine from nephrons to the renal pelvis Nephron Has A Unique Blood Supply Afferent arteriole – a small branch of the renal artery that carries blood to the glomerulus. Glomerulus- high pressure capillary bed that is the site of filteration. Efferent arteriole – a small branch of the renal artery that carries blood away from the glomerulus to the peritubular capillaries Peritubular capillary – a member of the network of small blood vessels that surround the tubule of the nephron Practice – Do questions 1-3 pg. 380