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Nutrition Science Databases How the database is build How to use it for data filing and data analysis Submit a Manuscript: http://www.wjgnet.com/esps/ Help Desk: http://www.wjgnet.com/esps/helpdesk.aspx DOI: 10.3748/wjg.v21.i29.8952 World J Gastroenterol 2015 August 7; 21(29): 8952-8963 ISSN 1007-9327 (print) ISSN 2219-2840 (online) © 2015 Baishideng Publishing Group Inc. All rights reserved. SYSTEMATIC REVIEWS Effects of cereal fiber on bow el function: A systematic review of intervention trials Jan de Vries, Paige E Miller, Kristin Verbeke Jan de Vries, De Vries Nutrition Solutions Inc., 7213 CE Gorssel, The Netherlands Solutions Inc., Reuvekamp 26, 7213 CE Gorssel, The Netherlands. [email protected] Telephone: +31-6-54224148 Paige E Miller, Center for Epidemiology, Biostatistics, and Computational Biology, Exponent, Inc., Chicago, IL 60661, United States Received: January 29, 2015 Peer-review started: January 30, 2015 First decision: March 10, 2015 Revised: April 15, 2015 Accepted: June 10, 2015 Article in press: June 10, 2015 Published online: August 7, 2015 Paige E Miller, Nutrition and Food Service, Edward Hines Jr. VA Hospital, Hines, IL 60141, United States Kristin Verbeke, Department of Clinical and Experimental Medicine, KU Leuven, 3000 Leuven, Belgium Author contributions: de Vries J contributed substantially to conception and design, acquisition of data, analysis of data and drafting the article; Miller PE contributed substantially to drafting the article; Verbeke K contributed to conception and design, analysis of data and drafting of the article. Abstra c t AI M : To comprehensively review and quantitatively summarize results from intervention studies that examined the effects of intact cereal dietary fiber on parameters of bowel function. Supported by Funding from Kellogg Company, Battle Creek, MI, United States. M ETHODS: A systematic literature search was conducted using PubMed and EMBASE. Supplementary literature searches included screening reference lists from relevant studies and reviews. Eligible outcomes were stool wet and dry weight, percentage water in stools, stool frequency and consistency, and total transit time. Weighted regression analyses generated mean change (± SD) in these measures per g/d of dietary fiber. Conflict-of-interest statement: Dr. de Vries J has received fees for systematically reviewing the literature reported in this publication from Kellogg Company, Battle Creek, MI, USA. Dr. Miller PE received fees while working at Exponent, Inc from Kellogg Company, Battle Creek, MI, USA, to support the writing process of the manuscript. Professor Verbeke K, PhD, is co-beneficiary of the WK Kellogg Chair in Cereal Sciences and Nutrition (Kellogg Company, Battle Creek, MI, USA). Data sharing statement: No additional data are publically available. Interested readers can contact the first author . RESULT S: Sixty-five intervention studies among generally healthy populations were identified. A quantitative examination of the effects of non-wheat sources of intact cereal dietary fibers was not possible due to an insufficient number of studies. Weighted regression analyses demonstrated that each extra g/d of wheat fiber increased total stool weight by 3.7 ± 0.09 g/d (P < 0.0001; 95%CI: 3.50-3.84), dry stool weight by 0.75 ± 0.03 g/d (P < 0.0001; 95%CI: 0.69-0.82), and stool frequency by 0.004 ± 0.002 times/d (P = 0.0346; 95%CI: 0.0003-0.0078). Transit Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer -reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/ Correspondence to: Dr. Jan de Vries, De Vries Nutrition WJG| www.wjgnet.com 8952 August 7, 2015| Volume 21| Issue 29| Construction database Physicochemical characteristics Ingredients Labeling information Safety information Reviews Projects Publications Supplier information Individuals Parameters Relevant documents Sample types Etc, etc Settings = defined as measurement Results intervention in 1 day = defined as timeline Interventions Study design Reports Results intervention > 1 day A set of tables that provides flexibility in the majority of the fields to be retrieved from publications. Advised to filled in as first step of a project. Workflow in database Reports Relevant documents A tool to make a report on a specific topin within the project A table that provides the possibility to include relevant documents for the project Reviews Project Projects Settings A table that provides the possibility to include relevant reviews for the project Publication Publication A set of tables that provides flexibility in the majority of the fields to be retrieved from publications. Advised to filled in as first step of a project. A table that provides the possibility to describe the characteristics of the interventions used in the studies Study design Physicochemical characteristics Publication Parameters Individuals Individuals Individuals Ingredients Sample types Etc, etc Labeling information Safety information Supplier information intervention Results intervention > 1 day = defined as measurement intervention Results intervention in 1 day = defined as timeline intervention Suppliers A table that provides the possibility to give details of the suppliers of the ingredients used in the studies Project Give projectname Give projectnumber Portal tab for added publications New publications ALWAYS needs to be added by this button Portal tab for added reviews Portal tab for added relevant documents, such as definition issues Selecting Settings Click this button to open menu options Click this button to go to settings Setting up the settings Value list for types of interventions Value Value Different listlistforfor tabs types other for of elements different interventions value of analysis lists retrieval of information from publication Always start with + in the project lay-out! New publications ALWAYS needs to be added by this button Tab in the portal to add specific information on included individuals in study Tab in the portal to add specific information on study design Tab in the portal to add parameters measured in the study Tab in the portal to add relevant references for the project from reference list Characteristics of individuals Click this button to add a new study group Study design Pup up window for entering information on the sample types Pup up window for entering information on time points studied Pup up window for entering information on the method to estimate food intake Click this button to add a new document that is related to the study design Workflow: parameters and statistics Workflow: characteristics interventions Click this button to enter a new intervention group Worksflow: results Click this button to enter one new parameter studied Click this button to enter one day a parameter is measured Click this button to enter all parameters studied Click this button to enter all days a parameter is measured Workflow: quality appraisal For human intervention studies the database contains 2 sets of quality appraisals to estimate the quality of the included study. Click on the button “Appraisal” to activate the pop-up menu for the appraisal of the quality. Analysing the data • Use the button “Functions” to get to the instruments that enable finding and exporting data • • • Developed to view the most important data of ONE single publication in the database Provides a list of ALL the results of measurement data of ALL publications in one project Provides a list of ALL the results of the timeline data of ALL publications in one project Lay-outs equiped to search AND export data to excel: • Provides a lay-out to search the data on measurement results within one project on ONE single parameters that reports on measurements. • Provides a lay-out to search the data on timeline results within one project on ONE single parameters that reports on measurements. • Provides a lay-out to conduct a more complex search. Search results are reported in a next lay-out of which measurement results can be exported • Provides a lay-out to conduct a more complex search. Search results are reported in a next lay-out of which timeline results can be exported Lay out to set up a specific search on the results Click this button after filling in the search characteristics for your search An example on how the search results could look like on a specific search Button for export of data to excel