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Imperial College London
Job Description
Job Title:
Research Assistant/Associate (maternity cover)
Section:
Structural Biology
Division:
Experimental Medicine
Department:
Medicine
Job Family and Level:
Academic and Research, Level A or B
Salary Range:
Level A: £29,350 - £32,520 per annum
Level B: £33,410 - £42,380 per annum
Responsible To:
Professors Paul Freemont and Xiaodong Zhang
Works closely with:
Research group
Location:
South Kensington Campus
Funding:
Cancer Research UK
Duration:
Full-time, fixed-term for 6 months
Research Programme
The multifunctional AAA ATPase p97 is involved in a myriad of cellular processes
including cell cycle regulation, membrane traffic, protein quality control, DNA
metabolism, signalling and apoptosis. Consequently mutations in p97 cause cell
deaths or various disease. Furthermore, p97 has been shown to be a potential target
for cancer treatment. The researcher will undertake structural and mechanistic
studies of p97 and its key cofactors, especially those involved in cancer pathways.
Job Summary
This is a temporary post to cover maternity leave for 6 months. The post will carry out
structural characterisations of p97 and its cofactors using cutting edge cryo-electron
microscopy single particle analysis.
Research Duties
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Plan, execute and analyse experiments
Maintaining an up-to-date detailed knowledge of relevant and recent
research literature
To maintain accurate and complete records of all findings
To ensure the validity and reliability of data at all times
Prepare and present findings to colleagues at seminars and lab
meetings
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Prepare and present findings to other researchers through scientific
publications and conferences
To train and supervise students or other members of the laboratories
or collaborators
Other Duties
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To be actively involved in related research and scholarly activities essential
for the project as a whole
To be responsible for the general good practice of the laboratory and to carry
out necessary tasks related to that (in agreement with supervisors)
To undertake appropriate administration tasks
To undertake limited teaching duties as required by the Department
To comply with relevant College policies, including Financial Regulations,
Equal Opportunities Policy, Promoting Race Equality Policy, Health and
Safety Policy, Information Systems Security Policy and Intellectual Property
Rights and Register of Interests Policies
To undertake any necessary training and/or development
To maintain safe workplace practice and procedures in accordance with the
requirements of Health and Safety legislation;
To maintain an up to date knowledge of relevant statutory Health and Safety
legislation and recommendations and attend safety training as required.
Any other duties commensurate with the grade of the post as directed by the
supervisor
Job descriptions cannot be exhaustive and so the post holder may be required
to undertake other duties, which are broadly in line with the above key
responsibilities.
The post holder is expected to observe and comply with all College policies
and regulations, for example Health and Safety, Data Protection etc.
Imperial College is committed to equality of opportunity and to eliminating
discrimination. All employees are expected to adhere to the principles set out
in our Equal Opportunities in Employment Policy, Promoting Race Equality
Policy and Disability Policy and all other relevant guidance/practice
frameworks.
Person Specification
Imperial Expectations
These are the 7 principles that Imperial leaders, managers and supervisors are
expected to follow:
1)
Champion a positive approach to change and opportunity
2)
Communicate regularly and effectively within, and across, teams
3)
Consider the thoughts and expectations of others
4)
Deliver positive outcomes
5)
Encourage inclusive participation and eliminate discrimination
6)
Support and develop staff to optimise talent
7)
Work in a planned and managed way
Qualifications
PhD or equivalent in structural biology (or passed PhD viva with minor
corrections)
Knowledge / Experience
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Knowledge of research methods in structural biology
Practical experience within a research environment carrying out electron
microscopy single particle analysis
Computer literate with a good knowledge of different computer programs
with experience in data presentation and statistical analyses
Skills and Abilities
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Demonstrated ability for innovative high quality structural biology research
High levels of organisation and attention to detail
High levels of initiative, innovation and problem solving skills
Ability to rapidly learn new research methods
Ability to undertake day-to-day supervision and training of other research
team members
Ability to conduct detailed reviews of research literature
Ability to develop and apply new concepts
Excellent verbal communication skills and the ability to deal with a wide range
of people
Excellent written communication skills and the ability to write clearly and
succinctly for publication
Ability to organise own work with minimal supervision
Ability to meet deadlines and research objectives
Advanced computer skills, especially electron microscopy image processing
packages
Personal Attributes
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Willingness to work as part of a team and to be open-minded and
cooperative
Flexible attitude towards work
Discipline and regard for confidentiality and security at all times
Willingness to undertake any necessary training for the role
Willingness to travel both within the United Kingdom and abroad to
conduct research and attend conferences