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Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma by Franziska Jundt, Ioannis Anagnostopoulos, Reinhold Förster, Stephan Mathas, Harald Stein, and Bernd Dörken Blood Volume 99(9):3398-3403 May 1, 2002 ©2002 by American Society of Hematology Lymph node biopsy specimens of cHD and ALCL.(A-D) Paraffin-embedded sections immunostained for Notch1 and counterstained with hematoxylin. Franziska Jundt et al. Blood 2002;99:3398-3403 ©2002 by American Society of Hematology High Notch1 and Notch2 expression in cultured HRS and ALCL cells.(A) Upper panel: Western blot analysis of cell lysate proteins from Hodgkin (lanes 1-5) cell lines, non-Hodgkin (lanes 6-10) cell lines, mature CD2+ T cells (lane 11), and mature CD19+B cells ... Franziska Jundt et al. Blood 2002;99:3398-3403 ©2002 by American Society of Hematology Activated Notch1 signaling promotes growth and survival of lymphoma cells.(A) Proliferative responses of Notch1-expressing lymphoma cells after activation by Jagged1. Franziska Jundt et al. Blood 2002;99:3398-3403 ©2002 by American Society of Hematology