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Mycotoxins
Phreusa T. 4328701
What are Mycotoxins??
Mycotoxin is a toxin produced by a
fungus under special conditions of
moisture and temperature.
What are Mycotoxins??
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5,000 years ago in China.
Early 1861, was reported in Russia
1891, there was a report of mouldy rice
in Japan
1960, is the time of the discovery of
aflatoxin.
Common Members of the
Mycotoxin Family
Aflatoxins
Trichothecenes
Zearalenone
Fumonisin
Ochratoxins
Slaframine
Food containing Mycotoxins
Mycotoxin
Aflatoxin
Organism
A. flavus, A. paraciticus
Foods
Corn,peanuts,cottonseed,
etc.
Penicillium citrinum
Wheat,barley,peanuts
Citrisin
Ochratoxin A A. ochraceus, R. veridicatum, Corn,barley,wheat,
R. cyolopium
peanuts
A. clavatus, R. patuluns
Patulin
Penicillic acid A. clavatus, R. puberulum
Alternaria tenuis, A. dauci
Alternariol
Silage, apples
Zearalenone
Fusarium roseum, E.
moniliforme, F. nivale, E.
oxysporum
Corn, sorghum, wheat
Fumonisin
Fusarium
Corn
Corn, beans
Weathered grain,
sorghum, pecan pickouts
What is Aflatoxin??
Aflatoxin is the name for a group of
toxins (poisonous chemical
compounds) that are produced by two
fungi called Aspergillus flavus and
Aspergillus parasiticus.
Aflatoxins
Four primary aflatoxins, named B1, B2, G1
and G2 plus two additional metabolic
products, M1 and M2. The case with
aflatoxin toxicity and carcinogenicity has
been established for aflatoxin - induced
mutagenic activity and DNA damage.
Foods
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Corn
Barley
Cottonseed
Peanuts
Sorghum
Wheat
Silage
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Tree nuts
Milk
Apples
Oats
Beans
Weathered grain
Potatoes
Symptom
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Edema of legs and
feet
Abdominal pain
Vomit
Acute hepatitis
Convulsion
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Cirrhosis
Carcinoma of liver
Fever
Jaundice
Acute necrosis
Malaise
Aflatoxicosis
Aflatoxicosis is primarily a hepatic disease.
Aflatoxin B1 and Tumor Induction
Aflatoxin B1 and Tumor Induction