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CURRICULUM VITAE Dr Giovanni Murtas Name and Surname Giovanni Murtas Nationality Address Italian Viale San Bartolomeo 15, int. 11, Grottaferrata, 00046 (RM) E-mail: [email protected] Cell-phone: +39 3405864656 Office: +39 (0)6 49934213 Home: +39 06 94546286 Telephone EDUCATION 1992 Doctoral degree in Biological Sciences Università di Roma "La Sapienza", Dip. Biologia Molecolare e Genetica. Thesis: "Functional characterization of the rolB gene promoter of Agrobacterium rhizogenes in planta WORK EXPERIENCE 2005-2009 Senior Grant Holder, Centro “E. Fermi” Roma. “Minimal life”: a Synthetic Biology approach to construct e semi-synthetic minimal cell as a model for early living cells Pubblications: 7, 8, 9, 10, 11, 12, 13, 14, 15, 16. 2007 (Jan-Feb) Visiting Scientist/Invited Lecturer, KITP, UCSB, Santa Barbara, USA Evolution of Molecular networks, Workshop and School 2003-2004 Visiting Scientist BioGeM/SZN,/ Università Roma Tre Research in Genetics and Genomics in Arabidopsis thaliana 1999-2002 Research Fellow Warwick University, Department of Biology, England, UK. Functional location of phytochrome function in Arabidopsis thaliana Publications 2, 4. 1994--1999 Post-doc. Cambridge Laboratory, JIC England, UK, ESD4, a gene regulating flowering time in Arabidopsis thaliana Lab Head: Prof. George Coupland Publications 1, 3, 5, 6. 1 1992-1994 Fellowship BBSRC, John Innes Institute, Virus Department UK. Functional characterization of the Helper component of the CaMV Virus. Lab Head: Prof. R. Hull. 1990-1992 Research towards the thesis, Università “La Sapienza” Dipartimento di Biologia Molecolare e Genetica, Rome Italy. Research work on the Agrobacterium Rhizogenes activity in plants. Supervisor: Prof. Paolo Costantino CONSULTING 2008 INVITED EXPERT (Synthetic Biology) /Workshop/FET Proactive – Shaping the next FP7workProgramme Designing alternative bio-inspired informationcommunication technologies (ICT) Brussels, 6 February 2008. PUBLICATIONS AND PATENTS 1) The regulation of flowering time by day length in Arabidopsis. G. Coupland, M.I. Igeno, R. Simon, R. Schaffer, G. Murtas, et al., Review, "Control of plant Development: Genes and Signals 1997 " Dublin .Publisher: SEB eds., 105. 2) How plants tell the time. Giovanni Murtas and Andrew J Millar. Current Opinion in Plant Biology 2000 (impact factor: 10.8), 3:43-46, Current Biology Publications, 3) Early in short days 4, a mutation in Arabidopsis that causes early flowering and affects the expression of the flowering time gene FLC. Giovanni Murtas*., Paul H. Reeves.* et al *Joint first authors. Development 2002 (impact factor 9.16), 129 (23): 5349 *4) The circadian clock that controls gene expression in Arabidopsis is tissue-specific. Simon Thain, Giovanni Murtas et al., Plant Physiology 2002 (impact factor 6.1); 130 (1) 102-110 *4) CIRCADIAN RHYTHMS Leaves Have More Than One Clock, EDITORS' CHOICE Science, STKE 2002,Vol. 2002, (impact factor 30.9) Issue 151, p., tw347 5) A nuclear protease required for flowering-time regulation in Arabidopsis reduces the abundance of SUMO conjugates. Giovanni Murtas et al.,.Plant Cell 2003 (impact factor 11.08), Oct 1, 15 (10) 6) Patent filed 5/6/1997 "Regulation of Flowering time with ESD4 gene" Inventors: Giovanni Murtas, Paul Reeves and George Coupland. 7) P.L. Luisi, P. Stano, G. Murtas, Y. Kuruma, T. Ueda En route to semi-synthetic minimal cells. In: "Proceedings of the Bordeaux Spring School on Modelling Complex Biological Systems in the Context of Genomics. April 3rd - 7th 2006" P. Amar, F. Képès, V. Norris, M. Beurton-Aimar and J.-P. Mazat (eds.).EDP Sciences, 2007, Les Ulis (Paris). pp. 19-30 8) Murtas, G., Kuruma, Y., Bianchini, P., Diaspro, A., Luisi, PL. Protein Synthesis in liposomes with a minimal set of enzymes Biochem Biophys Res Commun. 2007 Nov 9;363(1):12-7. Epub 2007 Aug 15. (impact factor 3.8), 2 9) Murtas, G The semi-synthetic “Minimal Cell”: a model for early living cells. Proceeding of the meeting: Basic Questions about the origin of life, Erice,Italy, 2-6 October 2006. OLEB 2007 10) Giovanni Murtas Minimal Cells during the origin of life Darwin, Editoriale Darwin S.r.l. 2007 November/December 11) Stano, P.; Murtas, G., and Luisi, P. L. Semisynthetic Minimal Cells: New Advancements and Perspectives In: "Protocells. Bridging Nonliving and Living Matter". S. Ransmussen, M. A. Bedau, L. Chen, D. Deamer, D. C. Krakauer, N. H. Packard and P. F. Stadler (eds.); MIT Press, 2009, Cambridge, Massachusetts; pp. 39-70. 12) Murtas G Internal lipid synthesis and vesicle growth as a step toward self-reproduction of the minimal cell. Systems and Synthetic Biology accepted for publication November 2009(DOI: 10.1007/s11693-009-9048-1) 13) Review/book: The evolution of protocells Giovanni Murtas et al., to be published in 2010 in Lectures on Synthetic Biology, publishing company: Morgan & Claypool 14) Book: Synthetic Biology Editors: Giovanni Murtas and Alfonso Jaramillo Publishing company: Springer, Boston, MA. USA. To be published in 2010 15) Review Artificial assembly of a minimal cell Giovanni Murtas , Molecular BioSystems, Mol Biosyst. 2009 Nov;5(11):1292-7. 16) Protein synthesis within liposomes. Giovanni Murtas Methods in Enzymology to be submitted in 2010 FUNDING The minimal cell project was funded by HFSP and Centro Enrico Fermi PRESS RELEASE New Scientist The Guardian BBC News “Life begins again” 7 July 2007 “Scientists a step nearer to creating artificial life” The Guardian Thursday September 6 2007 News - Science/Nature - Creating life in the laboratory, October 2007 CONGRESS/ORAL PRESENTATIONS 2006 2007 2007 2006“Basic questions about the origin of life” Ettore Majorana C., Erice, Italy, (Talk) Synthetic Biology 3.0 Conference, 24-27 June, ETH, Zurich, Switzerland, (Talk) Centro Enirco Fermi, November 2007, The project “minimal life” (Talk) 3 2008 Advances in Synthetic Biology, Wellcome Trust Centre, Cambridge, UK, 2007 2008 2008 Evolution of Molecular Networks, KITP, SantaB., California,USA, (Invited Speaker) Semi-Biotics Systems, Workshop EU network, , Malta, (Invited Speaker) Life under (re)constraction,S. on Synthetic Biology VBC, Vienna. (Invited Speaker) 2008 (Talk) International Frontieres in Synthetic Biology , Dicembre 1-2 2008, Harvard Medical School, Boston, Ma, USA Organizer/Scientific committee/ Speaker) 2009 European Systems & Synthetic Biology, 14-15 September 2009 Genopole, Evry FRANCE Organizer/Scientific committee/Speaker TEACHING Biological Sciences Department, Warwick University Lectures in Molecular Biology , 1999-2000 and 2000-2001 SZN/Naples, Italy Lectures in Biotechnology: 2001- 2002. Università Roma tre, Dipartimento di Biologia 2005-2006. 2 Lectures in Synthetic Biology 2007-2008. 4 Lectures in Synthetic Biology COMPUTING: Working knowledge in Windows PC and Macintosh: GCG analysis, Internet databases, Bio-Imaging programmes and Microsoft Excel, Power point LINGUAGE: Fluent in English and Spanish Course: English for “academic writing” (The University of Warwick) 4