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Downloaded from http://esmoopen.bmj.com/ on May 3, 2017 - Published by group.bmj.com Open Access Podcast Highlights from the San Antonio Breast Cancer Symposium 2015 Jacek Jassem To cite: Jassem J. Highlights from the San Antonio Breast Cancer Symposium 2015. ESMO Open 2016;1:e000043. doi:10.1136/esmoopen-2016000043 ▸ Prepublication history for this paper is available online. To view these files please visit the journal online (http://dx.doi.org/10.1136/ esmoopen-2016-000043). Accepted 5 February 2016 Department of Oncology and Radiotherapy, Medical University of Gdansk, Gdansk, Poland Correspondence to Professor Jacek Jassem; [email protected] https://soundcloud.com/bmjpodcasts/highlights-from-san-antonio-breast-cancersymposium-2015 A critical review on the practice changing studies presented at the San Antonio Breast Cancer Symposium, held December 2015, is presented in this podcast. A number of areas, including neoadjuvant and adjuvant treatment, treatment of metastatic disease and the emergence of new biomarkers are addressed. Trials discussed include the WSG-ADAPT HER2+/HR+ phase II trial, which assessed 12-weeks of neoadjuvant TDM1 with or without endocrine therapy versus trastuzumab+endocrine therapy in HER2-positive hormone-receptor-positive early breast cancer, the CREATE-X study, which assessed adjuvant capecitabine in patients with HER2-negative pathologic residual invasive disease after neoadjuvant chemotherapy, and the TH3RESA study, which investigated trastuzumab emtansine use in patients with previously treated HER2-positive metastatic breast cancer. Further, studies on new promising biomarkers such as the prognostic value of circulating tumour cells in follow up of early breast cancer patients after adjuvant chemotherapy are highlighted. Overall, the present podcast represents a comprehensive overview on some of the most important studies presented at the San Antonio Breast Cancer Symposium. Competing interests None declared. Provenance and peer review Commissioned; internally peer reviewed. Open Access This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work noncommercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/ by-nc/4.0/ Jassem J. ESMO Open 2016;1:e000043. doi:10.1136/esmoopen-2016-000043 1 Downloaded from http://esmoopen.bmj.com/ on May 3, 2017 - Published by group.bmj.com Highlights from the San Antonio Breast Cancer Symposium 2015 Jacek Jassem ESMO Open 2016 1: doi: 10.1136/esmoopen-2016-000043 Updated information and services can be found at: http://esmoopen.bmj.com/content/1/1/e000043 These include: Open Access This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Email alerting service Receive free email alerts when new articles cite this article. Sign up in the box at the top right corner of the online article. Topic Collections Articles on similar topics can be found in the following collections Open access (102) Notes To request permissions go to: http://group.bmj.com/group/rights-licensing/permissions To order reprints go to: http://journals.bmj.com/cgi/reprintform To subscribe to BMJ go to: http://group.bmj.com/subscribe/