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Products Miscellany and Supply Problems March/April 2016 Products Product Information Supply Now Available New product: This new strength has been added to the BuTrans® range of topical buprenorphine products (buprenorphine) available. It is licensed for use in adults with 15 non-malignant pain of moderate intensity microgram/hour when an opioid is necessary for obtaining transdermal adequate analgesia. patch Comments Dovobet® Gel Applicator Dovobet gel should be applied to the affected area once daily. The recommended treatment time is 4 weeks for scalp psoriasis and 8 weeks for mild to moderate nonscalp psoriasis. Dovobet® Gel Applicator (calcipotriol/betamethasone 60gdipropionate) is now available –as a new addition to the Dovobet® family. The company recommends the Applicator for “targeted and no touch application “areas of psoriasis, as the Applicator facilitates precise application, delivering 0.05g with every squeeze. Information for Community Pharmacists For Community Summary of recent distribution changes can Pharmacists if be accessed via the PSNC website or via unable to source this link: certain products Link to manufacturers contingency plans Cilique® oral contraceptive Cilique® (norgestimate 250mcg/ethinyllestradiol 35mcg) has been recently launched by Consilient Health. General Information Fusidic acid 1% Fucithalmic® eye drops have been eye drops discontinued by AMCo, but they are now making a generic fusidic acid 1% modified-release (MR) eye drops product instead. The cost of the eye drops has consequently increased from approx. £2.60 for Fucithalmic® eye drops 5g, to £29.06 for generic fusidic acid 1% MR eye drops 5g. Please be aware that chloramphenicol 0.5% eye drops are recommended as the first-line treatment for acute bacterial conjunctivitis in the majority of patients, where antibiotic treatment is required. Fusidic acid 1% MR eye drops should not be routinely used first line due to high cost and increased incidence of adverse effects. Locally, GPs are recommended to prescribe the Consilient health range of oral contraceptives as these are one of the most cost effective range currently. Key Messages: If a topical ocular antibiotic is considered necessary, local Antimicrobial Guidelines recommend chloramphenicol 0.5% eye drops first-line. Fusidic acid 1% MR eye drops (5g) should be reserved as a treatment option for patients who: are pregnant or breastfeeding have a personal or family history of blood dyscrasias (such as aplastic anaemia) are intolerant of chloramphenicol may require assistance in applying drops, e.g. young children or elderly people (fusidic acid requires twice daily administration. Tin Orchel Medicines Management Team Southampton City CCG D:\840969513.doc E-mail [email protected] Products Miscellany and Supply Problems March/April 2016 NHS stationery ordering portal Primary Care Support England (PCSE)’s online portal for ordering NHS stationery has gone live, and all community pharmacy contractors should have received registration letters. If any queries arise, the PCSE website has a number of helpful FAQs: HELP Revised SPC: Natrilix SR® (indapamide) Myopia, blurred vision and visual impairment have been added as potential adverse effects to treatment. Revised SPC: Aldactone® tablets (spironolactone) – all strengths Sections 4.4, 4.5 and 4.8 have been updated to include information on the risk of severe hyperkalaemia, information on the concomitant use of trimethoprim/sulfamethoxazole with spironolactone, and the adverse reaction pemphigoid. Section 4.4 now includes a paragraph on the laboratory monitoring of testosterone level to ensure maintenance of eugonadal testosterone levels and a warning on use of testosterone in men with hypertension. Revised SPC: Nebido® (testosterone) 1000mg/4ml, solution for injection Revised SPCs: Madopar® (levodopa/benser aside) products Revised SPC: Requip® 0.25 mg (ropinirole hydrochloride) Tablets Zika virus: updated travel advice for pregnant women by Public Health England (PHE) Zika virus infection: guidance for primary care www.medicines.org.uk For more information visit: www.medicines.org.uk For more information visit: www.medicines.org.uk SPC has been revised to warn that urine test results may give a false positive for ketone bodies. For more information visit: Peripheral oedema is now listed as an undesirable effect of ropinirole tablets. For more information visit: www.medicines.org.uk www.medicines.org.uk PHE and the National Travel Health Network and Centre (NaTHNaC) recommend that pregnant women should postpone nonessential travel to areas with active Zika transmission until after pregnancy. This is a change to the previous advice which encouraged pregnant women to avoid travel PHE has issued updated guidance clarifying advice on preventing sexual transmission to pregnant women and women planning pregnancy and advice for immunocompromised patients, and Guillain Barre syndrome, and a new section on performing minor procedures in the primary care setting. Tin Orchel Medicines Management Team Southampton City CCG D:\840969513.doc One query that has been raised a number of times is “Will I be charged for my order?” This question has arisen because the online ordering portal includes prices for many of the items. As stated in the relevant FAQ, contractors will not be charged for standard orders made using the portal. PCSE is committed to ensuring NHS England supplies are ordered responsibly and for this reason, prices for items are included to help contractors make an informed decision about what they need. (Note, there may be a charge for urgent supplies.) For more information visit: For more information: Zika virus updated travel advice for pregnant women - News stories - GOV_UK.mht For more information visit: Zika_virus_guidance _for_primary_care_01_March_2016_v3.0.pdf E-mail [email protected]