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Biochemistry –CHEM 3500-01– Spring 2010-Scott
Lecture: TR 9:00-10:40 AM Room 130 Sequoya
Instructor:
Dr. Tricia L. Scott
Office: 218C Sequoya Hall
Phone: 706-272-2494
Secretary: 706-272-4440
E-mail: [email protected]
Office Hours:
Monday: 9:00-10:40 AM and 12:15-1:30 PM
Tuesday and Thursday: 10:40-12:15 AM
Science Learning Center Hours (Seq 115):
Tuesday: 1:30-3:30 PM
Other hours available by appointment.
Course Materials:
Biochemistry: A Short Course by Tymoczko, Berg, and Stryer.
 A scientific calculator
Student Learning Objectives:
Upon completion of the course CHEM 3500 students should be able to:
1. Understand the biological environment including water, membranes, and buffered
systems.
2. Know the main classes of biopolymers, their building blocks, and understand their
three-dimensional structure.
3. Understand how enzymes work and what contributes to their activity, inhibition, and
overall regulation.
4. Understand membranes and transport of molecules across membranes.
5. Understand the energetics and organization of metabolic pathways.
6. Know key steps and intermediates in common metabolic pathways such as glycolysis,
TCA cycle, electron transport, and lipid metabolism.
7. Understand key steps in DNA replication and repair.
8. Understand key steps in the processes of transcription and translation.
ASSESSMENT
Exams (4 each)
Quizzes/Homework
Class Participation
Final Exam
60 %
10%
10 %
20 %
OBJECTIVES
[1 – 8]
[1 – 8]
[1 – 8]
[1 – 8]
GRADING:
Final letter grades will be based on four regular exams, a cumulative final exam, quizzes,
homework, and class participation.
Grading scale:
90% or better
80-89%
70-79%
60-69%
59% or below
A
B
C
D
F
I will NOT send grades by e-mail or phone. You must see me in person at my office to
discuss any grades. Some grades such as the final exam grade and final course average
will be posted on GeorgiaVIEW.
ATTENDANCE POLICY:
Attendance in lecture will be taken each day through a sign-in sheet. To earn credit for
class participation you need to attend lectures and actively participate in class
discussions. Please DO NOT sign the attendance sheet for someone else. If caught, both
parties will receive a zero for class participation. If you miss a day and your absence
causes you to miss an exam, quiz, or in-class assignment, you will receive a grade of zero
for that exam, quiz, or in-class assignment. There will be NO makeup quizzes given.
Only one lowest quiz score will be dropped. Makeup of missed in-class assignments
may be allowed with a valid excuse. No assignments will be accepted after the instructor
has graded and returned papers.
There will be NO makeup exams. The final exam grade will be used to replace the
lowest regular exam grade and therefore can be counted twice. If the final exam grade is
the lowest exam grade, then the final exam grade will be counted once and no regular
exam grade will be replaced. The final exam grade can be used to replace a zero for a
missed exam. Only one missed exam score may be replaced by the final exam. All
other missed exams will result in a grade of zero.
Any alleged errors in the grading of any exam, quiz, or assignment must be brought to the
attention of the instructor within one week of the return of that exam, quiz, or assignment.
Academic Honesty:
Acts which violate the academic integrity policy (e.g., cheating, plagiarism, etc.) of the
college will not be tolerated and will result in a grade of “F” for the course and referral to
the disciplinary committee. Calculators will be used in course work. If your calculator is
programmable, the instructor may reserve the right to inspect or erase any and all
programs prior to taking an exam or quiz.
How To Do Well In This Course:
1. Meet the prerequisites (It is assumed that you know this material BEFORE taking this
class): You need to be able to use logarithms and scientific notation; to rearrange and
solve algebraic equations; to balance chemical equations; to understand atomic structure
and reactivity; to calculate pH and use equilibrium constants; to identify and understand
the properties of functional groups such as reactivity and polarity; to calculate
concentrations; and to use various other skills learned in general and organic chemistry.
2. Read the textbook. Read the assigned chapters before coming to lecture (See
Tentative Schedule) and then review class notes after lecture. Lecture time is limited,
and we cannot possibly cover every detail of the book. Exam questions will come from
both material covered in lecture and in the textbook.
3. Do the homework problems in the textbook. Really do them, do not just read the
answers given in the back of the book.
4. Make a commitment to study. Don’t try to cram material the night before the exam.
Keep up with your work and studying and try not to get behind. Study a couple of hours
each day. There is a lot of material to learn! Biochemistry is a vast subject. This course
will be challenging and demanding, but hopefully very rewarding.
5. Use flash cards, study groups, and other study strategies.
6. Get help early. Don’t wait too long to come see me.
CELL PHONE AND ELECTRONIC DEVICE POLICY:
The use of cell phones or any other electronic communication devices during any lecture
or exam is prohibited. Cell phones must be turned off or switched to silent mode. If an
emergency situation exists, cell phone use may be permitted only with prior permission
from the instructor. The use of cell phones or other prohibited devices during class will
be reason for dismissal from the class that day. Any exam, quiz, or assignment missed
due to dismissal from class will result in a grade of zero.
WITHDRAWAL FROM THE COURSE: The last day to drop this class without
penalty is Monday, March 22, 2010. You will be assigned a grade of W. After this date,
withdrawal without penalty is permitted only in cases of extreme hardship as determined
by the Vice President for Academic Affairs; otherwise a grade of WF will be issued. The
proper form for withdrawing from all classes at the college after the official drop/add
period but before the published withdrawal date is the Schedule Adjustment Form.
Students who are assigned to the Academic Advising Center for advisement must meet
with an advisor or staff member at the Academic Advising Center (107 Liberal Arts
Building) to initiate the withdrawal process. All other students must meet with a staff
member or advisor at the Office of Academic Resources in the Pope Student Center to
initiate the withdrawal process. After meeting with the staff member or advisor, all
students will then finalize the withdrawal process in the Financial Aid Office. Students
who fail to complete the official drop/withdrawal procedure will receive the grade of F.
Withdrawal from class is a student responsibility. The grade of W counts as hours
attempted for the purposes of financial aid.
Disability Statement
Students with disabilities or special needs are encouraged to contact Disability Support
Services in Academic Resources. In order to make an appointment to obtain information
on the process for qualifying for accommodations, the student must contact the
Coordinator of Disability Support Services.
Contact information:
Andrea Roberson
Pope Student Center, lower level
706/272-2524
[email protected]
Workforce Development
If a student receiving aid administered by the DSC Workforce Development Department
drops this class or completely withdraws from the College, the Schedule Adjustment
Form must be taken to the Workforce Development Office located in Room 112 of the
Technical Education Building. The Office is open on the following schedule:
Monday/Tuesday/Thursday: 9:00 a.m.-12:15 p.m. and 1:30 p.m. - 5:00 p.m.
Friday: 8:00 a.m.- 12:00 p.m. The office phone number is 272-2635.
Tentative Schedule for CHEM 3500 Spring 2010
Week of
Tuesday
January 4
January 11
January 18
Chapter 2: Water, Weak Bonds, and the
Generation of Order Out of Chaos
Chapter 3: Amino Acids
Chapter 5: Basic Concepts of Enzyme
Action
Thursday
Chapter 1: Biochemistry and the Unity
of Life
Chapter 3: Amino Acids
Chapter 4: Protein Three-Dimensional
Structure
Chapter 6: Kinetics and Regulation
January 25
Exam 1 (Ch. 1-6)
Chapter 7: Mechanisms and Inhibitors
February 1
Chapter 8: Hemoglobin, an Allosteric
Protein
Chapter 9: Carbohydrates
February 8
Chapter 10: Lipids
Ch. 11: Membrane Structure and
Function
February 15
Chapter 12: Signal-Transduction
Pathways
Exam 2 (Ch. 7-12)
February 22
Chapter 14: Metabolism: Basic
Concepts and Design
Chapter 15: Glycolysis
March 1
Spring Break
Spring Break
March 8
Chapter 16: Gluconeogenesis
Chapter 17: Citric Acid Cycle
March 15
Chapter 18: Citric Acid Cycle
Chapter 19: Oxidative Phosphorylation
March 22
Chapter 20: Oxidative Phosphorylation
Chapter 21: Photosynthesis
March 29
Exam 3 (Ch. 14-21)
Chapter 23: Glycogen Degradation
April 5
Chapter 24: Glycogen Synthesis
Chapter 26: Fatty Acid Degradation
April 12
Chapter 27: Fatty Acid Synthesis
April 19
Chapter 33: DNA Replication
Chapter 34: DNA Repair
April 26
Exam 4 (23-24, 26-27, 32-34, 38-39)
May 3
Final Exam
Tuesday, May 4
8:00-10:00 AM
Chapter 32: The Structure of
Informational Macromolecules: DNA
and RNA
Chapter 33: DNA Replication
Chapter 38: The Genetic Code
Chapter 39: The Mechanism of Protein
Synthesis