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Stages of Mitosis Eukaryotic Cell Division Cell Division Facts • All living organisms start out from a single cell • The average Human has about 10 trillion cells! Chromosomes • During interpahse, genetic material exists as chromatin (DNA coiled around histones) • To prevent from getting tangled during division DNA coils further into Chromosomes. Chromosome = 2 Chromatids • Sister chromatids are copies of the exact same chromosome (same DNA sequence) • chromatid =1/2 of a replicated chromosome • Held together by a centromere Interphase: Between Divisions, Cell is preparing to divide • G1 phase = growth phase, cell gets bigger • S phase = synthesis phase, DNA replicates • G2 phase = Organelles multiply Mitosis PROPHASE • • • • Chromatin coils into chromosomes Nuclear envelope breaks down Spindle fibers and centrioles from Centrioles move to opposite ends of cell METAPHASE • Chromosomes are moved to the center of the cell by the spindle fibers • Centrioles act as anchors for the spinal fibers ANAPHASE • Centromeres split apart • Sister chromatids are pulled apart by spinal fibers • Each chromatid is now a separate chromosome Telophase / Cytokinesis • Cytoplasm is divided into • Cytokinesis is the 2 daughter cells division of the • Each daughter cell has its chromosomes and own set of chromosomes organelles between • Nuclear envelope reforms the 2 daughter cells • In plants a cell plate forms between 2 daughter cells • Chromosomes uncoil into chromatin • Note daughter cells are smaller than surrounding cells Websites to visit with Mitosis animations • http://www.biology.arizona.edu/Cell_bio/tutorials/ cell_cycle/cells3.html • http://www.cellsalive.com/mitosis.htm • http://www.johnkyrk.com/mitosis.html • http://www.csuchico.edu/~jbell/Biol207/animation s/mitosis.html • http://www.sci.sdsu.edu/multimedia/mitosis/ • http://www.lewport.wnyric.org/jwanamaker/anima tions/mitosis.html