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Long-Term Outcome of Administration of c-kitPOS Cardiac Progenitor Cells After Acute Myocardial InfarctionNovelty and Significance by Xian-Liang Tang, Qianhong Li, Gregg Rokosh, Santosh K. Sanganalmath, Ning Chen, Qinghui Ou, Heather Stowers, Greg Hunt, and Roberto Bolli Circulation Research Volume 118(7):1091-1105 April 1, 2016 Copyright © American Heart Association, Inc. All rights reserved. Experimental protocol. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Rat c-kitPOS CPCs. A, CPCs were stained for c-kit and visualized by confocal microscopy; B, ckitPOS CPCs were stained for c-kit and the c-kitPOS population identified by flow cytometry; C, Quantitation of c-kitPOS CPCs in passages 1 to 4 in culture after magnetic sorting. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Morphometric assessment of LV remodeling. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Echocardiographic and hemodynamic assessment of LV dimensions and function. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Analysis of BrdU incorporation. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Fluorescence in situ hybridization (FISH) for detection of Y-chromosome 1 year after cell transplantation. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Analysis of CPCs (c-kitPOS/CD45POS cells) 1 year after cell transplantation. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved. Analysis of Y-chromosomePOS (Y-ChrmsPOS), c-kitPOS, and BrdUPOS cells 1 year after cell transplantation. Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105 Copyright © American Heart Association, Inc. All rights reserved.