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Long-Term Outcome of Administration of c-kitPOS Cardiac
Progenitor Cells After Acute Myocardial InfarctionNovelty
and Significance
by Xian-Liang Tang, Qianhong Li, Gregg Rokosh, Santosh K. Sanganalmath, Ning
Chen, Qinghui Ou, Heather Stowers, Greg Hunt, and Roberto Bolli
Circulation Research
Volume 118(7):1091-1105
April 1, 2016
Copyright © American Heart Association, Inc. All rights reserved.
Experimental protocol.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Rat c-kitPOS CPCs. A, CPCs were stained for c-kit and visualized by confocal microscopy; B, ckitPOS CPCs were stained for c-kit and the c-kitPOS population identified by flow cytometry; C,
Quantitation of c-kitPOS CPCs in passages 1 to 4 in culture after magnetic sorting.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Morphometric assessment of LV remodeling.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Echocardiographic and hemodynamic assessment of LV dimensions and function.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Analysis of BrdU incorporation.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Fluorescence in situ hybridization (FISH) for detection of Y-chromosome 1 year after cell
transplantation.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Analysis of CPCs (c-kitPOS/CD45POS cells) 1 year after cell transplantation.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
Analysis of Y-chromosomePOS (Y-ChrmsPOS), c-kitPOS, and BrdUPOS cells 1 year after cell
transplantation.
Xian-Liang Tang et al. Circ Res. 2016;118:1091-1105
Copyright © American Heart Association, Inc. All rights reserved.
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