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Chapter 5 Assessment For many psychoactive drugs, such as nicotine and cocaine, the fastest way to get an effect is by inhaling the drug’s vapors True Caffeine and cocaine are both considered to be stimulant drugs True In some cases, repeated use of a drug leads to pharmacodynamics tolerance, which is based on Reduced sensitivity of neurons The threshold on a dose-response curve is the Lowest dose at which there is an observable effects of the drug If repeated exposure to a drug increases the activity of the CYP450 enzyme that is responsible for metabolizing that drug, then later doses will be less effective that the first few doses. This is an example of Drug disposition tolerance Psychoactive drugs reach the brain tissue by way of the Bloodstrem Among the psychoactive drugs, alcohol is classified as a(n) Depressant Behavioral tolerance is the result of learning to compensate for the disruptive effects of a drug True For most therapeutic effects, there is a maximum effect, and increasing the dose more just increases the number and type of side effects True Some drugs may act on all type of neurons by Altering the electrical potential across the cell membrane