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Date: 3/2014 To: Valued Clients From: BCM Medical Genetics Laboratories RE: Discontinuation Memorandum Effective April 21, 2014, the Medical Genetics Laboratories at Baylor College of Medicine will discontinue Test Codes: 3105 - Complex IV (COX) Deficiency Panel - Nuclear Genes 3335 - mtDNA Depletion Panel, Hepatocerebral Form 3080 - Mitochondrial DNA Depletion Syndrome Panel 3620 - Nuclear Encoded Complex I Deficiency Panel The above tests will be replaced by the following comprehensive Next Generation Sequencing based tests: 2170 - Mitochondrial Respiratory Chain Complex IV Deficiency Panel by Massively Parallel SM Sequencing (BCM-MitomeNGS ) SM 2130 - mtDNA Depletion/Integrity Panel by Massively Parallel Sequencing (BCM-MitomeNGS ) 2155 - Mitochondrial Respiratory Chain Complex I Deficiency Panel by Massively Parallel Sequencing SM (BCM-MitomeNGS ) Please direct any billing questions to 713-798-3566 or email us at [email protected]. Please visit our website for any additional notices or postings. Thank you for your valued business. We look forward to providing you with the highest quality genetic testing services. Sincerely, Sean Y. Kim General Manager Medical Genetics Laboratories Baylor College of Medicine One Baylor Plaza, MS: NAB2015 Houston, Texas 77030 / PHONE: 713-798-6555 / 800-411-GENE /FAX 713-798-6584 www.bcmgeneticlabs.org