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[ɒtilɒ gujaːʃ kovaːt͡ʃ] Attila Gulyás-Kovács “Colorless green ideas sleep furiously.” — Noam Chomsky Education 2006– graduate courses. probability theory, mathematical statistics, bioinformatics 2005 PhD, University of Göttingen, advisor: Erwin Neher. molecular and cellular biophysics Experience 2015– Postdoctoral Fellow, Icahn School of Medicine at Mount Sinai, Dept. Genetics and Genomic Sciences, Tu Lab. ␣ integration and interpretation of genomic data for personalized medicine 2012–2015 Visiting Scientist, Budapest University of Technology and Economics, Computational Biomedicine Workgroup (Péter Antal). ␣ ␣ ␣ researched miRNAs’ roles in breast cancer - prioritization of miRNAs with MKL machine learning [?] - Bayesian network-based relevance analysis of miRNA variants called from NGS data assisted in writing articles on novel bioinformatics methodologies taught in a bioinformatics course 2005–2012 Postdoctoral Researcher, Rockefeller University, Gadsby Lab. ␣ ␣ ␣ analyzed the protein defective in cystic fibrosis disease with mechanistic experiments developed data analysis software for colleagues (J Gen Physiol.;136(1):63-82.) published [?] his independent work on structural bioinformatics and sequence evolution 2002–2005 Doctoral Researcher, Max Planck Inst. for Biophysical Chemistry, Dept. Neher (Nobel Prize 1991). ␣ with mechanistic experiments dissected the roles of SM proteins in exocytosis [?, ?, ?, ?] Skills ␣ statistics, machine learning asymptotic theory, ML/Bayesian estimators, tests, decision theory graphical and generalized linear models, stochastic processes Bayesian graph learning, multiple kernel learning ␣ ␣ ␣ ␣ ␣ programming: R, Matlab, Python, Perl, Scheme, Bash document preparation: LATEX, Beamer, TikZ [email protected] • www.attilagk.com ␣ bioinformatics & computational biology NGS data pipelines and variant calling theoretical population genetics, evolution, phylogenetics comparative molecular modeling statistical mechanics, theoretical biophysics ␣ ␣ ␣ ␣ ␣ experimental PCR, molecular cloning techniques, DNA/RNA extraction Western blots, biochemistry wide range of electrophysiology and microscopy techniques ␣ ␣ ␣ ␣ languages: English, German, Hungarian Selected Presentations Seminars Conferences ␣ ␣ ␣ ␣ ␣ ␣ Columbia University Rockefeller University Albert Einstein College of Medicine Max Planck Inst. for Mol. Genet. VU University Amsterdam Biophysical Society Intelligent Systems for Mol. Biol. Society for Mol. Biology and Evolution Gordon Research Conferences ␣ ␣ ␣ Publications [1] Peter Marx, Bence Bolgár, András Gézsi, Attila Gulyás-Kovács, and Péter Antal. MicroRNA Prioritization Based on Target Profile Similarities. In International Conference on Bioinformatics Models, Methods and Algorithms - (BIOINFORMATICS 2014), 2014. [2] Attila Gulyás-Kovács. Integrated analysis of residue coevolution and protein structure in ABC transporters. PLOS ONE, 7(5):e36546, January 2012. [3] Attila Gulyás-Kovács, Heidi de Wit, Ira Milosevic, Olexiy Kochubey, Ruud F Toonen, Jürgen Klingauf, Matthijs Verhage, and Jakob B Sørensen. Munc18-1: sequential interactions with the fusion machinery stimulate vesicle docking and priming. The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(32):8676–86, August 2007. [4] Heidi de Wit, Alexander M Walter, Ira Milosevic, Attila Gulyás-Kovács, Dietmar Riedel, Jakob B Sørensen, and Matthijs Verhage. Synaptotagmin-1 docks secretory vesicles to syntaxin-1/SNAP-25 acceptor complexes. Cell, 138(5):935–46, September 2009. [5] Ruud F Toonen, Olexiy Kochubey, Heidi de Wit, Attila Gulyás-Kovács, Bas Konijnenburg, Jakob B Sørensen, Jürgen Klingauf, and Matthijs Verhage. Dissecting docking and tethering of secretory vesicles at the target membrane. The EMBO journal, 25(16):3725–37, August 2006. [6] Uri Nili, Heidi de Wit, Attila Gulyás-Kovács, Ruud F Toonen, Jakob B Sørensen, Matthijs Verhage, and Uri Ashery. Munc18-1 phosphorylation by protein kinase C potentiates vesicle pool replenishment in bovine chromaffin cells. Neuroscience, 143(2):487–500, December 2006. [email protected] • www.attilagk.com
