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Products Miscellany and Supply Problems September –October 2016
Products
Product Information
Products with a Supply Problem or Discontinued
Retigabine (Trobalt®)
The manufacturer of retigabine
(Trobalt®) has written to healthcare
professionals advising that this
medicine is to be discontinued.
Retigabine is licensed as an adjunctive
treatment of drug-resistant partial onset
seizures with or without secondary
generalisation in patients aged 18 years
or older with epilepsy where other
combinations have been inadequate or
not tolerated.
Comments
Clinicians should be aware of this product being
discontinued. It would be prudent to run clinical
system searches to identify any patients who are
currently prescribed this product to allow a review
and arrangements made to identify a suitable
alternative.
The decision to discontinue this product
is a commercial one based on limited
use and a decline in new patients being
started on this treatment. There are no
safety concerns.
It is recommended that treatment is
gradually withdrawn over a period of at
least three weeks and safety monitoring
should continue during treatment. No
new patients should be started on this
treatment. The manufacturer is working
with regulatory authorities and suppliers
to ensure that this medication remains
available for the next year to allow time
for alternative treatment to be identified
and initiated.
Supply Now Available
New product:
Glycopyrronium Bromide
1 mg/5 ml Oral Solution
Quantum Pharmaceuticals have
launched a licenced glycopyrronium
bromide 1mg/5ml oral solution.
NHS list price =£91.00
This is licensed for use in adults as an
add-on therapy in the treatment of
peptic ulcer.
Available via all local wholesalers.
Polyvinyl alcohol 1.4% eye
drops
Polyvinyl alcohol 1.4% eye drops and
Polyvinyl alcohol 1.4% eye drops
0.4ml unit dose preservative free are
classified as medical devices and
these products are no longer being
manufactured as licensed medicines.
The medical devices containing
polyvinyl alcohol that have been
approved as appliances are listed in
Part IXA of the Drug Tariff in the eye
products category. Polyvinyl alcohol
1.4% eye drops preservative free may
also be prescribed and sourced from a
manufacturer holding a MHRA specials
licence.
Prescribers may wish to consider
whether a patient would be able to
use one of the unit dose preservative
free products as an alternative to
prescribing a ‘special’.
Tin Orchel Medicines Management Team Southampton City CCG
There are currently 3 licensed oral glycopyrronium
bromide preparations :
Glycopyrronium bromide 1mg/5ml 150ml=£91.0
Glycopyrronium bromide 2mg 30 tabs=£229.20
Glycopyrronium bromide 1mg 30 tabs=£206.63
There is a professional requirement that where a
product is ordered on a prescription, a pharmacist
must supply a product with a marketing
authorization, where such a product exists and is
available, in preference to an unlicensed medicine.
The products in Part IX are listed by proprietary
name or generic name + supplier.
There is a professional requirement that where a
product is ordered on a prescription, a pharmacist
must supply a product with a marketing
authorization, where such a product exists and is
available, in preference to an unlicensed medicine
E-mail [email protected]
Products Miscellany and Supply Problems September –October 2016
Fluoxetine preparations
There are newly licensed fluoxetine
preparations now:
•fluoxetine oral solution 20mg/5ml
70ml=£3.06
•fluoxetine dispersible 20mg tabs
28=£3.44
•fluoxetine 20mg caps 30=93p
•fluoxetine 10mg caps 30=£55.00
•fluoxetine 30mg caps 30=£1.80
•fluoxetine 40mg caps 30=£1.80
•fluoxetine 60mg caps 30=£9.98
Licensed products now
Diazepam 2mg/5ml oral suspension
available
(Special Order) has been discontinued.
A licensed option Diazepam 2mg/5ml
oral suspension is available from
Sandoz Ltd.
Cost- 100ml=£31.75
Other licensed diazepam preparations
include tablets, rectal solution tubes and
injections.
Licensed products now
Instead of using Naproxen 125mg/5ml
available
(Special Order) which is unlicensed,
use of Naproxen125mg/5ml oral
suspension sugar free (Orion Pharma
(UK) Ltd) which is licensed –cost
100ml=£110.00
Alternatively consider licensed
Naproxen 250mg (Stirlescent®)
effervescent tablets -cost:
20 tablets=£7.90
Information for Community Pharmacists
MHRA Drug Safety Update MHRA Drug Safety Update August
&September 2016:
There is a professional requirement that where a
product is ordered on a prescription, a pharmacist
must supply a product with a marketing
authorization, where such a product exists and is
available, in preference to an unlicensed medicine.
There is a professional requirement that where a
product is ordered on a prescription, a pharmacist
must supply a product with a marketing
authorization, where such a product exists and is
available, in preference to an unlicensed medicine.
There is a professional requirement that where a
product is ordered on a prescription, a pharmacist
must supply a product with a marketing
authorization, where such a product exists and is
available, in preference to an unlicensed medicine.
DSU_August_2016.p
df
Sept_2016_DSU.pdf
General Information
Which oral vitamin D
dosing regimens correct
deficiency in pregnancy?
This UKMi Q&A evaluates the available
evidence at the time of publication to
address issues associated with vitamin
D dosing. Published 11th September
2014, updated 30th August 2016 ·
UKMi in pregnancy.
QA-Vitamin-D-and-pr
egnancy-329_3-FINALV2.doc
Tin Orchel Medicines Management Team Southampton City CCG
E-mail [email protected]