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Cardiovascular Disease COURSE NO: IDIS 5621 DIRECTORS: Lisa Mendes, Steve Eskind, Steve Ball, & Julie Damp WHEN OFFERED: Sections 9 and 1 ENROLLMENT: Min 4 Max 8 (up to 16 students/year) PREREQUISITES: FCC medicine and surgical clerkships PRECIS: The course will expose the student to a broad range of cardiovascular diseases, focusing on foundational science as well as clinical topics that are applicable to students going into any specialty in which they will care for patients with cardiovascular diseases. Foundational science topics will include cardiovascular physiology and hemodynamics, electrophysiology, anatomy, histology, and pharmacology. All students will participate in a core series of didactics and workshops, but will be allowed to choose clinical experiences in cardiology, cardiothoracic surgery, vascular surgery, and cardiothoracic anesthesia. Clinical care will occur in a variety of settings including the wards, intensive care unit, operating room, outpatient clinics, and diagnostic laboratories. The course will provide flexibility to allow the interested student to have experiences in at least two clinical specialties. In addition, the curriculum is designed to encourage teamwork and knowledge sharing through interactive conferences and work groups. Critical Illness COURSE NO: DIRECTORS: WHEN OFFERED: ENROLLMENT: PREREQUISITES: IDIS 5613 Tracy McGrane and Meredith Pugh Sections 9, 11 and 2 Min 16 Max 24 (up to 72 students/year) FCC all clerkships PRECIS: Regardless of a student's individual specialty choice, each will be called upon to provide competent care for critically ill patients during their residency training. The successful management of critically ill or injured patients requires a thorough understanding of physiology, pathophysiology, and pharmacology. By combining targeted teaching with hands-on experiences in different ICUs across the medical center, Critical Illness will deepen knowledge of the anatomy, physiology, pathophysiology, imaging, biostatistics, ethics, microbiology, neuroscience, nutrition science, pharmacology, and behavioral medicine inherent in critically ill patients. In the first week, all students will be immersed in Critical Care Skills Week, a highly regarded simulation-based learning experience that culminates in receipt of Fundamentals of Critical Care Support (FCCS) certification. All students will spend a week caring for patients in the Medical, Surgical, Burn, Neurologic, Cardiovascular, or Pediatric ICU. The other 2 weeks will be spent in learner-focused case-based education facilitated by ICU faculty, ICU radiology and palliative care sessions, additional patientcentered experiential learning opportunities and hands-on workshops in ICU-specific technical skills such as airway management, ventilator manipulation, and chest tube placement. Community Healthcare: Patients, Populations and Systems of Care COURSE NO: IDIS 5614 DIRECTORS: Jule West WHEN OFFERED: Sections 9, 2 and 5 ENROLLMENT: Min 4 Max 8 (up to 24 students/year) PREREQUISITES: FCC all clerkships PRECIS: In Community Healthcare, students will be equipped to effectively address predictors of poor health on an individual level, and to engage healthcare systems in ways that promote meaningful change. Students will move beyond an investigation of the social determinants of health to provide individualized patient care and engage the healthcare system. Regardless of the field students decide to enter, they will encounter vulnerable populations of patients and should be equipped to address patient needs in ways that promote healing. Foundational science topics will include population health, health policy, health determinants, community engagement, systems engineering, public health, organizational management, health ethics, resource utilization, implementation science, behavioral science, and communication science. The course is comprised of clinical experience in a safety net clinic, seminar sessions with local and national experts to facilitate skill development, and completion of a final project. The course will equip students with a “portable toolkit” of skills that can be used in any field of practice in any location. This course qualifies for primary care credit. Diabetes Mellitus COURSE NO: DIRECTORS: WHEN OFFERED: ENROLLMENT: PREREQUISITES: IDIS 5624 Mike Fowler and Al Powers Sections 8, 9, 10, 11, 2, 3, 4 and 5 Min 2 Max 4 (up to 32 students/year) FCC medicine clerkship PRECIS: Diabetes mellitus is a worldwide pandemic. One in twelve United States adults now suffers from the disease, and in the near future this number will likely increase to one in ten. Physicians in any specialty/subspecialty can expect to care for patients with diabetes, especially because patients with diabetes have higher rates of hospitalization, surgical complications, cardiovascular disease, infection and other morbidities. Therefore most, if not all, physicians in training should be competent in basic treatment of diabetes in the inpatient and outpatient settings and understand the current and future areas of research and medical practice as related to diabetes. This course is designed to teach our medical students how to care for the patient with diabetes mellitus, regardless of their specialty of choice, as well as to understand the basic science, social effects, bearing on public health, and human impact of this disease. Additionally, biomedical research in diabetes involves many fields of research such as cardiovascular disease, physiology, molecular biology, genetic medicine, cell biology, and neuroendocrinology. As a medical center whose goal is to train future researchers and leaders in medicine, Vanderbilt must offer experiences in diabetes patient care and research to its students. This immersion will include components of clinical training as well as an academic project exploring the limits of current scientific knowledge about diabetes care and treatment. Getting Hooked: Addiction COURSE NO: IDIS 5623 DIRECTORS: Meg Benningfield and Christine Konradi WHEN OFFERED: Sections 11, 1, 2 and 4 ENROLLMENT: Min 4 Max 8 (up to 32 students/year) PREREQUISITES: FCC Psychiatry and Neurology PRECIS: Addiction is a highly prevalent, chronic brain disease that affects nearly every organ system in the body. A leading cause of morbidity and mortality, addiction is preventable and treatable, but only about 10% of those affected receive appropriate treatment. Patients with problems related to addiction may present for care in any setting across the health care system. It is therefore essential for all physicians to be well versed in the basic principles of addiction medicine. This 4-week course will be an opportunity to synthesize the neuroscience of addiction with clinical skills in assessment and treatment of addictive disorders. The primary goals of the course are to train future physicians: to recognize addiction as a chronic brain disorder; to effectively screen for substance use disorders in varied clinical settings; to treat or refer patients for specialized treatment as indicated; and to consistently approach patients with addiction with compassion and respect. In addition, this course serves as an opportunity to return to the foundational medical knowledge underlying the pathophysiology and treatment of addictive disorders and integrate this knowledge with clinical care. Key concepts of foundational medical knowledge will be reviewed including neuroanatomy, mechanisms of neurotransmission, pharmacology, epidemiology, and cell biology as they relate to addiction medicine. Students will use online modules and independent study for instruction on foundational medical knowledge and in-class time will be focused on discussion and integration of the material with clinical experience. Global Health COURSE NO: DIRECTORS: WHEN OFFERED: ENROLLMENT: PREREQUISITES: IDIS 5618 Doug Heimburger Sections 2, 8, 10; special requests for other sections may be granted Min 2 for a given site Max 3-4 per site (up to 20 students per block) FCC all clerkships PRECIS: Students who participate in the Global Health ISC will gain a deep understanding of diseases in resource-constrained settings through the lens of population science, epidemiology, public health, health systems, health policy, and other issues related to international development. In this monthlong clinical rotation, students are placed at Vanderbilt’s partner sites in various locations around the world including, but not limited to, Central America, Jordan, and Kenya. Once on-site, students participate in a variety of rotations ranging from one to four weeks, which are designed based on both the student’s interests and the mentorship and resources available at the site. During rotation, students complete weekly online modules that introduce key concepts in global health and related foundational sciences. Foundational science topics include population health science, public health, pathology and pathophysiology (for both infectious diseases and non-communicable diseases), nutrition science, epidemiology, social sciences, behavioral sciences, health systems sciences, and microbiology (other foundational science areas could be covered depending on the site). Additional health and developmental issues that span nations and cultures, and which require collaborative, partnership-based action, are highlighted. The course is taught through interactive digital lectures, readings from peer-reviewed journals, on-site exposures to patients, health systems, and communities, and distance mentoring sessions with Vanderbilt faculty. In the month prior to departure, students complete pre-departure online modules as well as attend a pre-departure orientation session to prepare them for immersion. As a participant, you will have the opportunity to hone foreign language skills and to develop lasting partnerships in a cross-cultural setting with our international colleagues. Immunity and Infections in the Immune-compromised Host (I3CH) COURSE NO: IDIS 5625 DIRECTORS: Daniel Dulek WHEN OFFERED: Sections 8, 10, 1, and 3 ENROLLMENT: Min 4 Max 8 (up to 32 students/year) PREREQUISITES: FCC medicine or pediatric clerkship PRECIS: The human immune system is a complicated but beautiful system that impacts nearly every subspecialty in medicine. An understanding of normal and pathologic immunity is critical for physicians to be at the forefront of emerging medical advances. Using stem cell transplantation, organ transplantation, immune deficiency, and infectious diseases as a model for understanding the human immune system, this ISC reinforces and extends foundational knowledge in immunology and infectious diseases in a manner that can be applied to other subspecialties and disciplines. Given the expanding array of immunosuppressive therapies in medicine, special attention is give to understanding infectious complications of immunosuppression. The course employs a variety of learning formats—including didactic lectures, team-based learning, journal clubs, case discussions, and a cutting-edge topic presentation—to fulfill learning objectives focused on understanding mechanistic immunology in clinically-relevant settings. During the course, students spend a week at a time in each of four clinical settings—hematopoietic stem cell transplantation, solid organ transplantation, transplant infectious diseases, and outpatient transplantation clinics. Foundational science topics include immunology, microbiology, molecular biology, pathology, genetics, and pharmacology. Infectious Diseases COURSE NO: DIRECTORS: WHEN OFFERED: ENROLLMENT: PREREQUISITES: IDIS 5628 Natasha Halasa and Holly Algood Sections 7, 12 and 3 Min 3 Max 9 (up to 27 students/year) FCC medicine PRECIS: A WHO report warns that infectious diseases are spreading more rapidly than ever before and that new infectious diseases are being discovered at a higher rate than at any time in history. This elective is for students with an interest in learning more about how to diagnose and treat patients with infectious disease. Students will also learn how to use antibiotics appropriately and manage the complications of HIV and other chronic infections. The diversity of patient population will afford the student a breadth of experience in evaluating and managing patients with infectious diseases. In this clinic-driven experience, students are placed in a series of 3 week-long clinical experiences in various settings including inpatient, outpatient and laboratory medicine and are introduced to key topics and concepts in infectious diseases including symptoms, diagnosis, treatment, vaccines, and antibiotic stewardship. Methods to establish an etiologic diagnosis and rational use of antibiotics are emphasized. Foundational science topics include Epidemiology, Immunology, Microbiology, Virology, Pathology and Pathophysiology. The course is taught through online modules/lectures, clinic exposures to patients, team-based learning, and case presentations. Injury, Repair, and Rehabilitation COURSE NO: IDIS 5627 DIRECTORS: Mayur B. Patel and Lillian B. Nanney WHEN OFFERED: Sections 9, 11, 4 and 6 ENROLLMENT: Min 6 Max 8 (up to 32 students/year) PREREQUISITES: FCC medicine and surgical clerkships PRECIS: In the US, injuries are the leading cause of death among persons ages 1–44 years of age, which results in more deaths than non-communicable diseases and infectious diseases combined. In this course, students will be exposed to the continuum of injury, repair, regeneration, and rehabilitation through the multidisciplinary viewpoints of emergency medicine, trauma surgery and associated surgical subspecialties, such as anesthesia, hematology & transfusion medicine, physical & occupational therapy and speech-language pathology. Students will spend portions of their clinical experience on the trauma service supplemented by rotations through rehabilitative, recovery, and palliation settings. Didactics will focus on shock, hemostasis and thrombosis, wound healing and regeneration of skin, bone and nerves, nutrition, acute and chronic pain management, speech-language pathology, age and co-morbid factors, brain injury, case-based learning across the continuum from acute to long-term recovery, as well as palliative care and death. Integrated foundational sciences are anatomy, epidemiology, ethics, immunology, implementation science, neuroscience, nutrition sciences, pathology, pathophysiology, pharmacology, radiobiology, social sciences, system sciences. Following experiential anatomic learning and practice, successful students will obtain four-year American College of Surgeons Advanced Trauma Life Support (ATLS) certification, as well as audit the Advanced Surgical Skills Exposure for Trauma (ASSET); both courses are coordinated using the facilities of the Program for Advanced Anatomy and Simulated Skills (PASS) and the Center for Experiential Learning and Assessment (CELA). This course will serve as a prerequisite to the Advanced Clinical Experience in Trauma. Medical Imaging and Anatomy COURSE NO: IDIS 5626 DIRECTORS: Cari Buckingham and Lillian Nanney WHEN OFFERED: Sections 8, 10, 1 and 3 ENROLLMENT: Min 4 Max 8 (up to 32 students/year) PREREQUISITES: FCC medicine and surgical clerkships PRECIS: Imaging is an essential component of the diagnosis and treatment of disease across all fields of medicine. Every physician interacts with medical imaging both in emergent and non-emergent settings. Therefore, each student requires knowledge of the utility, indications, acquisition, interpretation, limitations, and risks of medical imaging. Furthermore, it is crucial that physicians understand how imaging affects patient care and management and how it fits into the larger healthcare delivery system. This course will strengthen and expand upon prior learning in anatomy, embryology, pathophysiology, neuroscience, and pathology and introduce students to radiobiology and radiation effects, imaging physics, imaging ethics, radiologic pharmacology, and biostatistics. The course will consist of a two week “general” portion for all students and a two week “selective” portion in one of the following: neurologic imaging, cardiothoracic imaging, body imaging, or musculoskeletal imaging (limited space for each selective). Self-paced didactic podcasts and case series as well as live lectures, small group discussions, and student presentations will accompany clinical exposure to medical imaging in diagnostic, interventional, therapeutic, and operative settings. Additionally, students will participate in anatomy and pathology labs and will learn and be evaluated in basic ultrasound scanning technique. After this course, students will feel confident with key anatomy, be able to make several “do-not-miss” imaging diagnoses, and will be able to use imaging more safely and appropriately. Precision Cancer Medicine COURSE NO: IDIS 5620 DIRECTORS: Kimberly Dahlman, Mary Hooks, and Vicki Keedy WHEN OFFERED: Sections 9, 2 and 5 ENROLLMENT: Min 3 Max 12 (up to 36 students/year) PREREQUISITES: FCC Medicine and either Surg, Ob/gyn, Peds PRECIS: Precision medicine is the tailoring of patient therapy based on pharmacogenetic biomarkers that predict the likelihood of drug response or risk of adverse events, and highlights the importance of foundational science translation in improving patient outcomes. Although precision medicine can be applied to a number of diseases, oncology, arguably, sits at the forefront. Over the last decade there has been an increase in the understanding of cancer molecular drivers and based on this information, gene mutation-specific inhibitors have been successfully used in the clinic that target only sub-populations of patients with particular tumor genotypes. As a result, there is a need for oncologists to have an appreciation of the fundamental molecular biology underlying the patient’s tumor to effectively translate tumor genotype to precision patient care. This course will provide a unique experience in oncology where medical and graduate students work together to explore the molecular drivers of cancer and how that information is translated into targeted cancer therapies. Foundational science topics will include anatomy, physiology, histology, biochemistry, cell biology, genetics, molecular biology, immunology, pathology, radiobiology, and toxicology. Students will explore the concepts of oncogene addiction, acquired resistance to targeted therapy, immunotherapy, tumor heterogeneity, and drug discovery through seminars, team-based learning, and case-based learning activities. The information learned will be used as a platform to describe how molecular changes are detected in the laboratory and leveraged in the clinic for personalized patient care. Students will select 3 of the following clinical settings for their clinical experiences: medical oncology, pediatric oncology, radiation oncology, surgical oncology, genetic counseling, pathology, and interventional oncology. Students will examine the multidisciplinary teams necessary in the care of cancer patients and the benefits of and challenges that precision medicine offers to oncologists through participation in tumor boards. Students will also have the ability to pursue their own interests in oncology through individualized projects. The Skinny on Obesity — What Every Physician Should Know COURSE NO: IDIS 5622 DIRECTORS: John Cleek and C. Robb Flynn WHEN OFFERED: Sections 9, 10, 2, 3 and 4 ENROLLMENT: Min 2 Max 8 (up to 40 students/year) PREREQUISITES: FCC medicine, surgical and pediatric clerkships PRECIS: Rates of obesity are rising all around the world and physicians confront it daily regardless of specialty. Whether clinicians or surgeons, general practitioners or specialists, pediatricians or internists, we all face a need and an opportunity to offer effective prevention and care of obesity and its comorbidities. In this course, students will be exposed to the evolution of this disease across these life stages, highlighting clear opportunities for prevention and treatment. They will have the opportunity to participate in a variety of multidisciplinary clinical and community settings, which range from general to subspecialty, and from medical to surgical. Through these clinical experiences and a core of didactics and discussions, students will learn key points of obesity, including prevention, treatment, and management of its comorbidities. Foundational science topics will include behavioral sciences, biochemistry, endocrinology, genetics, implementation science, neuroscience, nutrition sciences, pathology, pathophysiology, pharmacology, physiology, social sciences and system sciences. This course is designed to help students develop the unique knowledge, attitudes, skills, and behaviors needed to play an influential role in addressing this disease process. Sexual Medicine and Reproductive Health COURSE NO: IDIS 5629 DIRECTORS: Mary Romano & Doug Milam WHEN OFFERED: Sections 7, 10, 12, 4 ENROLLMENT: Min 4 Max 6 (up to 24 students/year) PREREQUISITES: FCC Medicine and Surgery clerkships PRECIS: This course will vastly deepen students’ knowledge of sexual medicine and reproduction, focusing on the foundational science as well as clinical experiences that will provide students with the knowledge they need to care for patients of all ages. Students will pursue these topics far deeper than what is taught in second year clinical clerkships. Foundational science topics will be addressed in a series of team based learning activities that will integrate foundational science with relevant clinical experience. This course will integrate the anatomy, physiology, pathophysiology and pharmacology of sexual function and reproduction with the clinical skills necessary to interview and assess patients in these areas of medicine. Students will become familiar with a core set foundational published literature and pursue one area more deeply leading to a brief paper. At the completion of this course, students will thoroughly understand the mechanisms of sexual function and reproduction and should be able to assess sexual development, sexual dysfunction, and fertility and to develop an appropriate and sensitive treatment plan. Students should be able to approach patients about the sensitive topics of sexual health, function, identify and reproduction with knowledge, compassion and cultural sensitivity.