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KTN Ltd and the Health Community Prof Mehdi Tavakoli, KTN Ltd Achieving Patient Access to Highly Novel Medical and Regenerative Technologies Wednesday 9 April 2014 York KTN Ltd and the Health Community • On April 1st 2014 the current Knowledge Transfer Networks merged to become a single company • to better represent the interdisciplinary nature of innovation • evolution not revolution • Chris Warkup is the CEO of The KTN • Sue Dunkerton part of senior leadership team • Most Health KTN staff joined the new entity KTN: Building a Healthy Nation through Business Innovation KTN Ltd supports business innovations through partnerships, access to funding and knowledge transfer. Connecting Partners • Bringing together & facilitating collaborations with a common goal Access to Funding • Identify and influence new and existing sources of funding Knowledge Transfer • Opening doors to wider networks of people/organisations UK Health Priority Areas Emerging Medical Technologies Novel High Value Manufacturing Regenerative Medicine Synthetic Biology Detection and Identification of Infectious Agents Assisted/ Independent Living Clinical Needs Biopharmaceutical & Bioprocessing Therapies Stratified Medicine Data and Digital Healthcare Health Community in Regen Med • • • • Support community engagement activities across the breadth of the RegenMed sector – Make links across priority areas and KTN communities : from bioprocessing to transport to sensors to creative – Industrially led Interest Groups Meetings eg: • Cardiovascular • Bioprocessing for Advanced Therapies • Unmet Clinical Needs – Clinical interactions – Engagement with relevant RC funded centres: EPSRC, MRC – Engage with UKRMP – Support the ATMP manufacturing Community – Work with CT Catapult – Support Trade associations work eg BIA CTRMAC Input to Gov’t led initiatives – BIS, DH, RMEG Identify KT gaps and address by catalysing community building Support development of partnerships involved in TSB funding Supporting Organisations International National Regional Charities Healthcare UK MediWales UKTI BIS FCO-SIN One Nucleus European BioTech Network NICE Medilink UK MHRA Regener8 Companies NISCHR DH RMEG NOCRI Medilinks KTN (Health) NIHR FDA IKC TSB ABHI/BIVD A BIA/ABPI European Commission BioNow HTCs DECs BRCs/BRUs Research Councils AHSN Network AHSNs NHS Trusts/ Clinicians Centres for Inn. Manufacture Universities Doctoral Training Centres Finance for Innovation Excellence in Science Framework 7 Leadership in KEITs Cooperation Health/NMP/ICT EUROPE H2020 www.FP7uk.co.uk Business Angels Societal Challenges PPP’s Innovation Platforms BioMedical Catalyst TSB Collaborative R&D Catapults NATIONAL www.innovateuk.org Venture Capitalists KTP SBRI TSBSmart Devolved Administrations/ Regional Funding Smart: Scotland Manufacturing Advisory Service (MAS) R&D Grant: Scotland Regional Growth Funds i4i DoH/NIHR RESEARCH COUNCILS Case Awards HICF HTCs www.nihr-ccf.org.uk/site/programmes/i4i www.rcuk.ac.uk Responsive Mode Research KTA Private Investors Industrial CASE AWARDS Managed Programmes IKCs TECHNOLOGY READINESS LEVEL (TRL) 1 2 Basic Research 3 4 5 Applied Research 6 7 8 Commercialisation 9 What Happens next– how will we make an impact? • KTN, Medical Technologies IKC and Regener8 worked together to bring this meeting and community together • The output of today with recommendations will be summarised in a report that will be presented to the Regenerative Medicine Expert Group in support of its work in this area • RMEG will be hopefully view the delegate list from today as a GO-TO community for further input, recommendation and learning to support this workstream • KTN and partners will work to continue connecting and catalyse innovation _connect portal www.healthktn.org www.innovateuk.org THANK YOU [email protected] Priority Areas-Clinical Needs • Identifying unmet clinical needs and influencing future funding calls (eg TSB Reg Med 2014). • Facilitating industry/clinicians collaborations through events. • Identifying funding opportunities and collaborating partners. • Access to leading clinicians and clinical centres of excellence. • Close collaboration with DH, NHS, NIHR , NICE, NOCRI, NHS24, NISCHR , HSCNI and influencing future national healthcare innovation strategy. • Close collaborations with clinicians-led major initiatives e.g. HTCs, DEC’s, AHSNs, BRCs, etc. • Facilitating commercialisation of new products, accelerating regulatory approvals and adoption by the NHS. Clinicians/Industry Collaborations Links to Clinicians-Health Technology Cooperatives( HTC) NHS Organisation Cambridge University Hospitals NHS Foundation Trust Sheffield Teaching hospitals NHS Foundation Trust University Hospitals of Birmingham NHS Foundation Trust Leeds Teaching Hospitals NHS Trust Clinical Area or Theme Brain Injury - Several theme areas around brain injury of acquired and developmental origin across the acute care pathway: acute care including bedside monitoring, imaging, stem cells, genomic profiling and biomarkers. Devices for Dignity - Urinary incontinence and management, renal technologies, assistive and rehabilitative technologies. Trauma Management - Four clinical themes, which mirror the patient journey: Immediate Care, Secondary Care, Regeneration, Rehabilitation. Colorectal Therapies - Minimally invasive therapies for colorectal disease with three themes: Engineering, nanotechnology, biosensing. Chronic gastrointestinal (GI) disease - Including prevention of stoma complications, neuromodulation for faecal incontinence, novel diagnostics to stratify chronic GI Barts Health NHS Trust disease, improved safety and effectiveness of GI surgery. Guy’s and St Thomas’ NHS Cardiovascular disease - Four themes: Artherosclerosis, Cardiac arrhythmias, Heart Foundation Trust failure and structural heart disease. Bradford Teaching Wound Prevention and Treatment - Wound management - patient led centralised Hospitals NHS Foundation wound research strategy. Trust Nottinghamshire Mental Health and neurodevelopmental disorders - Attention Deficit Hyperactivity Healthcare NHS Trust, Disorder, Tourette’s Syndrome and autism, depression and bipolar disorder. Institute of Mental Health Healthcare Technology Co-operatives (HTCs) Colorectal Therapies HTC Leeds Teaching Hospitals NHS Trust . Wound prevention and treatment HTC Bradford Teaching Hospitals NHS Foundation Trust . Mental health and neurodevelopmental disorders HTC Nottinghamshire Healthcare NHS Trust, Institute of Mental Health Brain Injury HTC Cambridge University Hospitals NHS Foundation Trust Devices for Dignity HTC Sheffield Teaching Hospitals NHS Foundation Trust Chronic gastrointestinal disease (enteric) HTC Barts Health NHS Trust Trauma Management HTC University Hospitals of Birmingham NHS Foundation Trust Cardiovascular disease HTC Guy’s and St Thomas’ NHS Foundation Trust Links to Clinicians-NIHR-Diagnostic Evidence Co-operatives