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Forensic Science Lecture 9 Introduction to Drugs Donald J. Ross, M.D. Drugs: Introduction Chapter 8 in textbook Narcotics Hallucinogens Depressants Stimulants Club drugs Anabolic Steroids Addiction • Healthcare workers and society have a primitive understanding of addiction • Best analogy for a family with an addict; family with a leukemia patient. • The disease is so devastating for families it is like having a loved one suffering from leukemia Addiction • However, in addition to receiving little or no community or social support there is a great deal of shame for the family dealing with the addict • Criminal activity associated with addiction, for example the “One Man Crime Wave” One Man Crime Wave • $750 a day heroin habit • Needed to rob 3 homes or 15 - 25 cars per day • Fell off the roof of a school trying to steal the newly installed air conditioning unit • Kept his “kit”, syringe, spoon, cotton and lighter inside a 2nd flashlight, gloves • Had singlehandedly devastated one town Addiction • Immense cost to society; prison, health, families • Only effective treatment appears to be meetings which are social, emotional and spiritually based • Group meetings; addicts meet with each other; talk about their addictions and how it effects their lives; AA, NA, etc.. • With this 75% will continue in their addiction Opiates What to look for in an addict Pinpoint pupils; http://thefranklinlakesjournal.com/franklinlakesnj/su spected-heroin-arrest/ Also causes constipation Heroin http://www.123rf.com/stockphoto/heroin.html Heroin – highly addictive opiate generally injected. Responsible for majority of overdoes Dosage in unknown Once injected dose is immediately available to addict OxyContin • • • • • Why let Pablo Escobar have all the money? Opiates in a tablet form Widely used and abused Doctor shopping Elderly in Florida caught selling pills Methadone • Government sponsored free opiate give away program • Addicts are given opiates Cocaine Addictive stimulant Powder form is “snorted” Hard crystal form may be smoked, “Crack” Injected Derived from Coca leaves Methamphetamines Stimulant Can be made at home using easy to acquire ingredients http://www.lynnpolice.org/ingredients_of_meth.htm Meth Lab • • • • • • • • UNUSUAL ODORS –smell of cat urine or rotten eggs COVERED WINDOWS –blacken or cover windows STRANGE VENTILATION –unusual ventilation ELABORATE SECURITY –"Keep Out" signs, guard dogs, video cameras, or baby monitors placed outside DEAD VEGETATION – dump toxic substances in their yards, leaving burn pits, EXCESSIVE OR UNUSUAL TRASH – packaging from cold tablets lithium batteries, stained coffee filters, empty containers of antifreeze, white gas, ether, starting fluids, Freon, lye, drain opener, paint thinner, acetone, alcohol, or other chemicals plastic or rubber hoses, duct tape, rubber gloves, or respiratory masks Illinois Attorney General 2010 Recognizing Meth Alcohol • Alcohol and alcohol related deaths will consume a great deal of time for any forensics office • Including MVA, overdoses, domestic violence leading to homicide, suicides, drowning and fights leading to death • A depressant Barbiturates and Benzodiazepines Sedatives Barbiturates are very dangerous especially when mixed with alcohol. Accidental overdoses are common with this mixture Benzodiazepines work in a similar fashion in the body but are less dangerous. Are less dangerous when mixed with alcohol, but can still result in death. Difficult to OD on Benzodiazepines alone Pain Killers Vicodin – Codeine and Tylenol; Hydrocodone bitartrate and acetaminophen • Many other names most are opiate based • Fentanyl transdermal system – very powerful – Case: PhD injecting fentanyl Hallucinogens • Marijuana; • loss of basil ganglia, memory center • Increased schizophrenia Hallucinogens Psychedelics (5-HT2A receptor agonists) Tryptamines Lysergamides Phenethylamines Serotonin releasing agents Substituted methylenedioxyphenethylamines Cannabinoids (CB-1 receptor agonists) Dissociatives NMDA receptor antagonists κ-Opioid receptor agonists Deliriants Anticholinergics Club Drugs 1) Methylenedioxymethamphetamine (MDMA) Ecstasy, E, X, XTC, Adam, Clarity, Lover’s Speed An amphetamine-based, hallucinogenic type drug that is taken orally, usually in a tablet or capsule form. 2) Gamma-hydoxybutyrate (GHB) Grievous Bodily Harm, G, Liquid Ecstasy, Georgia Home Boy A central nervous system depressant that is usually ingested in liquid, powder, tablet, and capsule forms. 3) Methamphetamine Speed, Ice, Chalk, Meth, Crystal, Crank, Fire, Glass A central nervous system stimulant, often found in pill, capsule, or powder form, that can be snorted, injected, or smoked. 4) Ketamine Special K, K, Vitamin K, Cat Valium An injectable anesthetic used primarily by veterinarians, found either in liquid form or as a white powder that can be snorted or smoked, sometimes with marijuana. 5) Rohypnol Roofies, Rophies, Roche, Forget-me Pill Tasteless and odorless sedative, easily soluble in carbonated beverages, with toxic effects that are aggravated by concurrent use of alcohol. 6) Lysergic Acid Diethylamide (LSD) Acid, Boomers, Yellow Sunshines Hallucinogen that causes distortions in sensory perception, usually taken orally either in tablet or capsule form. Often sold on blotter paper that has been saturated with the drug. FBI; Tips for Parents: The Truth About Club Drugs Anabolic Steroids Increased muscle mass Aggression Can leave males infertile if not correct balance of steroids Forensic Science Lecture 10 Overdose Donald J. Ross, M.D. Killing Mules I • • • • • Motel White male seated in chair at small table Found by cleaning lady Last seen alive by hotel clerk night before Pick-up truck parked in parking lot, Florida plates Killing Mules I, cont. • Syringe still in left hand, top of fist, on table, with syringe facing away from deceased • No visible scaring or “track marks” • No Tattoos • Both plastic hotel room key cards in room Killing Mules I, cont. • No evidence of other narcotics, alcohol, trash, bathroom clean, bed still made • Room is “clean” • “Overdose” • No legal evidence to label this a homicide Killing Mules II • • • • • Motel Hispanic male lying between beds Found by cleaning lady Last seen alive by hotel clerk night before Bags with Cuba tags; route Cuba to Ontario, Canada then Newark Airport • Rent Porn movies Killing Mules II, cont. Autopsy notification; tried all day with wife’s co-workers Called home repeatedly, no answer 10 pm left message She calls back immediately and understandably refuses to believe the reality of what has happen Killing Mules II, cont. • He was going to open a restaurant, they had just married • Deceased was in a great need for start-up money for the restaurant • Wife was unaware of what he was doing and only knew he had gone away on business • Planned to open the business once he return from the trip Girl in Mother’s Home • Syringe in arm • Covered with tattoos • Recently fired from job at doctors office due to stealing blank prescription forms • Wealthy family and a very nice home • Family was concerned neighbors and friends would read about overdose in the newspaper Last Seen Alive Teen user Last seen alive by local police and friend Considered detaining Due to problems with family claiming officer was targeting son and harassing him officer did not detain Later found deceased in basement at home Syringe in ankle Placed on Sidewalk Party at home for business owners workers Deceased found outside of home on sidewalk Clearly body was moved based on rigor mortis being broken and position Syringe found in sock on body 911 call came to PD from nearest payphone, video surveillance from bank showed homeowner’s car passing bank just prior and after the phone call Coin in phone box matched homeowners prints Suicide, with Cat Older female with cat lost job, and being evicted Used NyQuil gel caps to overdose Also tried to give away her cat, but when no one wanted it she poisoned it as well. Her cause of death was respiratory depression due to diphenhydramine overdose Russian Lady Middle-aged female Russian used book called Final Exit as a guide to taking her life She had been arrested for shoplifting Due to the family shame she took her life using a combination of diphenhydramine and also had with her a bottle of cyanide, which she did not use Final Exit is sold in the self-help section of some major books stores Dr. Happy Pain Clinic doctors Many are considered nothing more than drug pushers Dr. Happy had months earlier, emailed a prescription to a guy no more than 18 years old. The prescription was for 400 tablets of Xanax (Alprazolam, benzodiazepine) The 18 year old was found dead a few days after coming out of Re-hab Dr. Happy, cont. After coming home to live with his mother and father following re-hab , he was invited to a party at a residence across the street from his home He enjoyed the party but was found dead in one of the beds at the home Back at his home was found the 400 tablets of Xanax with other unfilled prescriptions Dr. Happy was suspected of providing the medications causing the young man’s death Dr. Happy, cont. Conversation with Dr. Happy He somehow got himself mixed up with some very bad people They were using his name and prescription license to send 1000’s of prescriptions to anyone who wanted one over the internet He had never examined or saw the deceased young man or any of the 1000’s sent prescriptions Conversation with Dr. happy was like a confession. Dr. Happy, cont. • The young man died as a result of stealing the grandmother’s medication where the party was being held. • He did not die due to Dr. Happy’s prescriptions • Later the DEA kicked in Dr. Happy’s door, but the fate of Dr. Happy is unknown.