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Cranial nerves and special senses [email protected] Word roots • • • • • • • • vagus (L.): wandering trochlea (G.): pulley glossus (G.): tongue cochlea (L.): snail chiasm (L.): cross rectus (L.): straight ocul, -i, -o (L.): eye opt- (L.): eye (optic, opthalmic etc.) Special senses • • • 5 „„traditional‟‟ senses: Touch, smell, sight, hearing and taste. “touch” is what we have already talked about, and is a colloquial term for general sensation. This is covered by peripheral nerves and cranial nerves. The cranial nerves cover the special senses, and equilibrium (not traditionally covered). Cranial nerves • Cranial nerves (CN) are part of the PNS. • Nerves attach to the brainstem (except for CNI and CNII - direct connection to brain). • Synapse within distinct nuclei (collections of cell bodies) in brainstem (equivalent to grey matter of the spinal cord). Mnemonics 12 cranial nerves I II III IV V VI VII VIII IX X XI XII Olfactory Oh Optic Oh Oculomotor Oh Trochlear To Trigeminal Touch Abducens And Facial Feel Vestibulocochlear Very GlossopharyngealGooey Vagus Veal Accessory And Hypoglossal Ham Some Say Marry Money But My Brother Says Big Boobs Matter More S - sensory M - motor B - both Moore and Dally (2009). Clinically Oriented Anatomy Cranial nerve nuclei Collections of grey matter within distinct locations throughout the brainstem. These are equivalent to the grey matter collections (ventral and dorsal horns) in the spinal cord. CN I : Olfactory Sensory only Special sense: Smell Passes through cribriform plate of ethmoid bone and synapses immediately onto olfactory bulb (second order neurons) No connection to thalamus Internal view of the skull CN II : Optic Sensory only Sight (special sensory) Passes through optic canal in sphenoid bone Neurons from retina (back of eyeball) Half of neurons cross over at optic chiasm (peripheral visual fields) Visual Pathway Visual fields Retinal fields First order neuron in eyeball Optic nerve Second order neuron from eyeball to thalamus Optic chiasm Optic tract Lateral geniculate body (thalamus) Optic radiation Visual cortex (occipital lobe) Third order neuron from thalamus to occipital lobe Eye Three layers of the eyeball: * fibrous coat - cornea (transparent) - sclera (white part) * vascular coat (uvea) - iris - lens - choroid (vessels) Ellis (2010) Clinical Anatomy * neural coat - retina --> synapse to neurons that form CN II Vision Vision CN III: Oculomotor Motor (Autonomic and Somatic) Passes through superior orbital fissure of sphenoid bone controls extrinsic eye muscles (movements of the eyeball) controls size of pupil and shape of lens CN IV: Trochlear Small ligament holds the superior oblique muscle in place. This acts like a pulley, which is where this nerve gets it‟s name from. Motor (somatic) Passes through superior orbital fissure Controls the Superior oblique muscle moves the eye down and out Superior view of left orbit CN V: Trigeminal Sensory and motor (depending on branches) Three branches: - Opthalmic (V1) - Maxillary (V2) - Mandibular (V3) Only mandibular has motor fibres (controls muscles of mastication) Exit foramina for CNV (sensory branches) Supraorbital notch (part of V1) Infraorbital foramen (part of V2) Mental foramen (part of V3) CN V: Trigeminal All three branches provide sensory innervation to the face Each branch passes through a different hole in the skull: - Opthalmic - superior orbital fissure - Maxillary - foramen rotundum - Mandibular - foramen Ellis (2010). Clinical Anatomy (modified) Tongue Moore and Dally (2009). Clinically Oriented Anatomy (modifie Sensory distribution of trigeminal nerve CN VI: Abducens Motor (somatic) Nerve passes through superior orbital fissure in the skull controls the Lateral rectus muscle abducts the eyeball Eye - many cranial nerves involved! 3 muscles to control extrinsic eye muscles * CN III oculomotor - medial rectus, superior recuts, inferior rectus, inferior oblique * CN IV trochlear - superior oblique * CN VI abducens - lateral rectus CNIII, the oculomotor nerve, has parasympathetic fibres. This controls the size of the pupil (how much light enters the eye) and the shape of the lens. CN II, optic nerve carries the visual information back to the visual cortex, where it is interpreted and integrated with other information. Moore and Dally (2009). Clinically Oriented Anatomy CN VII, facial nerve carries PSNS fibres to teh lacrimal gland. This produces lubricating film (tears) that keeps the eye moist. CN VII: Facial Motor (somatic and autonomic) and special sensory Passes through the internal acoustic meatus, through temporal bone, exits stylomastoid foramen Special sensory to tongue (taste) Motor to muscles of facial expression Facial nerve Special sensory: Taste Anterior 2/3 tongue The facial nerve also supplies PSNS innervation to the lacrimal glands (tears) and salivary glands. Moore and Dally (2009). Clinically Oriented Anatomy (modified) CN VIII: Vestibulocochle ar Sensory (special) Hearing (cochlear part) Equilibrium (vestilbular part) Passes through internal acoustic meatus Cochlea (L.) = snail Marieb (2009). Human Anatomy and Physiology (modified). Martini (2009). Human Anatomy and Physiology (modified). Martini (2009). Human Anatomy and Physiology (modified). CN IX: Glossopharynge al Motor (somatic) and sensory (special and somatic) Passes through the jugular foramen sensory for the tongue (general sensation and taste) sensory for the pharynx (throat) Glossopharynge al nerve The glossopharyneal nerve provides general sensation (touch, pain, temperature etc) AND special sensation to the posterior 2/3 of the tongue CN X: Vagus Motor (somatic and autonomic) Passes through jugular foramen Voluntary motor control of laryngeal muscles (controls voice) Autonomic (PSNS) motor control of gut, salivary glands, heart rate (slows). CN X: Vagus CN XI: Accessory Motor (somatic) Ascends through foramen magnum, then passes through jugular foramen Trapezius Sternocleidomastoid CN XII: Hypoglossal Motor (somatic) Passes through hypoglossal canal (near foramen magnum) Distinct location - roots between olives and pyramids on medulla oblongata Voluntary motor control of tongue muscles Thalamus Pons Medulla oblongata Anterior view of dissected brain stem and thalamus Tongue MOTOR = HYPOGLOSSAL only! XII Glossopharyngeal nerve (CNIX) TASTE and GENERAL SENSORY Facial nerve (CNVII) TASTE Trigeminal nerve (CNV) GENERAL SENSORY Skull foraminae Peripheral nerves (test yourself) Posterior compartment of the thigh Radial nerve Spinal segments of brachial plexus Intrinsic foot muscles plantar surface Sensory innervation to the face Motor innervation of facial muscles Peripheral nerves (test yourself) Posterior compartment of the thigh Radial nerve Spinal segments of brachial plexus Intrinsic foot muscles plantar surface Sensory innervation to the face Motor innervation of facial muscles Tibial n. Posterior arm and forearm muscles C5-T1 Lateral and medial plantar nerves (Tibial n.) Trigeminal nerve CNV Facial nerve CNVII Test yourself Test yourself Corpus callosum parieto-occipital sulcus Frontal lobe Anterior cerebral artery Pons cerebellum 4th ventricle