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Pharmaceutical Dosage Forms By S.Bohlooli, PhD School of Medicine, Ardabil University of Medical Sciences Dosage Form/ Drug Delivery System by route of administration Oral Tablets Capsules Solutions Syrups Elixirs Suspensions Magmas Gels Powders Sublingual Tablets Troches and Lozenges Parenteral Solutions Suspensions Conjunctival Contact lens inserts Ointments Dosage Form/ Drug Delivery System by route of administration Epicutaneous / transdermal Ointments Creams Infusion pumps Pastes Plasters Powders Aerosols Lotions Transdermal patches, discs, solutions Intraocular/ intraaural Solutions Suspensions Intranasal Solutions Sprays Inhalers Ointments Intrarespiratory Aerosols Dosage Form/ Drug Delivery System by route of administration Vaginal Solutions Ointments Emulsion foams Gels Tablets Inserts, suppositories, sponges Rectal Solutions Ointments Suppositories Urethral Solutions suppositories Solid Dosage Forms Powders and Granules Capsules and Tablets Powders and Granules Powders Blending Powders Medicated Powders Aerosolized Powders Granules Effervescent Capsules Hard Gelatin Capsules Soft Gelatin Capsules Hard Gelatin Capsules Tablets Compressed tablets (C.T.) Multiple Compressed tablets (M.C.T.) Sugar-Coated Tablets (S.C.T.) Film Coated Tablets (F.C.T) Gelatin Coated Tablets Enteric Coated Tablets (E.C.T.) Buccal or Sublingual Tablets Chewable Tablets Effervescent Tablets Molded Tablets Immediate release Tablets (I.R.) Instant Disintegrating /Dissolving Tablets Extended release Tablets (E.R.) Vaginal Tablets Compressed Tablets contains: Medicinal agent Diluents or filler Binders or adhesives Disintergrants Lubricants Miscellaneous adjuncts Colorants and flavorants Tablets Compressed tablets Gelatin Coated Tablets Multiple Compressed tablets Enteric Coated Tablets Sugar-Coated Tablets Film Coated Tablets Modified-Release Dosage Forms and Drug Delivery Systems Modified Release Extended Release Delayed Release Repeat action Targeted Release Terminology of extended release Sustained Release (SR) Sustained Action (SA) Prolonged Action (PA) Controlled Release (CR) Extended Release (ER) Timed Release (TR) Long Acting (LA) Modified-Release Dosage Forms Extended Release Example of oral control release capsule Nonoral Modified-Release Systems Ocular Parenteral Systems Vaginal Inserts Subdermal Implants Ocusert: Pilocarpine Modified Released System Example of Parenteral extended action products Example of vaginal extended release products Example of Subdermal extended release products Semi-Solid Dosage Forms Ointments Creams Gels Pastes Plasters Transdermal Drug Delivery Systems Example Of transdermal Drug delivery systems Pharmaceutical Inserts Suppositories Inserts Liquid Dosage forms Solutions Disperse systems Solutions Oral Solutions Otic Solutions Ophthalmic Solutions Topical Solutions Spirits Oral Liquid Dosage Forms Oral solutions Syrups Elixirs Tinctures Example of Syrup Antihistamine Syrup 1. Chlorpheniramine maleate 2. Glycerin 3. Syrup base 4. Sorbitol solution 5. Sodium Bezoate 6. Alcohol 7. Color and Flavor 8. Purified water to make 0.4g 25.0ml 83.0 ml 283 ml 1.0 g 60.0 ml q.s. 1000.0ml Example of Elixir Theophylline Elixir 1. Theophylline 2. Citric acid 3. Liquid Glucose 4. Syrup 5. Glycerin 6. Sorbitol Solution 7. Alcohol 8. Saccharin Sodium 9. Lemon Oil 10. FDC Yellow No. 5 11. Purified water to make 5.3 g 10.0 g 44.0 g 132 ml 50.0 ml 324.0 ml 200.0 ml 50 g 0.5 g 0.1 g 1000.0 ml Disperse Systems Suspensions Emulsions Aerosols Sterile Dosage Forms and Delivery Systems Parenterals Biologicals Ophthalmic solutions and suspensions Injection Types Automatic injection Medi-Jector:Needle Free Novel and Advanced Dosage Forms, Delivery Systems, and Devices Iontophoresis Phonophoresis Intravenous controllers and infusion pumps, lyposomes Iontophoresis Phonophoresis Intravenous controllers