Download Course Syllabus Course: Principles of Infectious Diseases PHS

Course Syllabus
Course:
Principles of Infectious Diseases
PHS 5334 / 3 credits / Fall 2015
Meeting Times:
Tue & Thu 9:45-11:00; VMIA 220
Instructor:
Andrea Bertke, PhD
Assistant Professor of Infectious Diseases
2030 ILSB
504-231-5733
[email protected]
Office Hours:
Tue & Thu 11:00 – 12:00 PHS Dept Office 394
By appointment at ILSB.
Course Description
Survey of basic principles of infectious diseases important in local, national, and global public health. This
course covers bacterial and viral pathogens and the mechanisms by which they cause disease, as well as
the host’s immune response to those pathogens.
Learning Objectives
Having completed the course, students will be able to:
 have an understanding of basic principles of bacteriology, virology, and immunology;
 have an understanding of various modes of transmission of infectious disease agents;
 recognize and compare different microbial diseases, including properties of different types of
pathogens and the mechanisms of pathogenesis;
 summarize the role of the host response in infectious diseases, including natural barriers to
infection, innate and acquired immune responses to infection, and inflammation;
 present information related to infectious diseases agents in a clear and concise manner through a
variety of communication methods
These objectives are in line with and set the foundation for required competencies of MPH graduates
from the Infectious Disease Concentration. Graduates are to be able to:



describe biological concepts relevant to public health;
articulate one health model of population-based health that reflects the human, animal,
environmental health interdependency;
identify and describe local, regional, national, and global infectious disease problems.
Textbook (Recommended but not required)
Medical Microbiology, 7th edition. Murray PR, Rosenthal KS, Pfaller MA.
Control of Communicable Diseases Manual, 19th edition. Heymann DL.
Additional literature references will be provided as needed and posted on Scholar.
Course requirements
This course is lecture and problem based. Students are expected to read assigned readings, complete
online quizzes, complete and present a project, participate in group exercises, and be prepared to
discuss knowledge obtained from these activities. The project will be an individual assignment, with
details provided after the first exam. Class grade will be determined as follows:
Exam #1
25%
Exam #2
25%
Final Exam
30%
Online quizzes 10%
Project
10%
Overall letter grades will be assigned as follows (based on the grading scheme of the College of
Veterinary Medicine):
A
94-100
C+
79-81.9
A91-93.9
C
76-78.9
B+
88-90.9
C73-75.9
B
85-87.9
D
<73
B82-84.9
Final Exam: Friday Dec 11 7:45-9:45 VMIA 220
The final exam will be weighted. Most of the exam will be virology but there will be a cumulative
component of the exam.
Honor System
All students are bound to the VPI & SU Honor System, which is outlined in the current University Policies
for Student Life manual and in the Graduate Honor System Constitution, a copy of which may be found at
http://ghs.grads.vt.edu/ghs_constitution.html. Students should review, in particular, the section on
plagiarism, which includes “the copying of the language, structure, idea, and/or thoughts of another and
claiming or attempting to imply that it is one's own original work. It also includes the omitting of quotation
marks when references are copied directly, improper paraphrasing (see plagiarism), or inadequate
referencing of sources. Sources used in preparing assignments for classes, theses, dissertations,
manuscripts for publication, and other academic work should be documented in the text and in a
reference list, or as directed by the instructor or professor. Sources requiring referencing include, but are
not limited to, information received from other persons that would not normally be considered common
knowledge (plagiarism), computer programs designed or written by another person, experimental data
collected by someone else, graded permanently-returned materials such as term papers or other out-ofclass assignments (koofers), as well as published sources.”
Services for students with disabilities
We cooperate with the Services for Students with Disabilities (SSD) office to accommodate qualified
students with disabilities. Please refer to the SSD website, http:/www.ssd.vt.edu, for additional
information.
Virginia Tech Principles of Community
All of us will abide by the Virginia Tech Principles of Community and everyone will treat each other
equally and fairly. Please refer to the website, http:/www.vt.edu/diversity/principles-of-community.html, for
additional information.
Class Policies
Laptops: You are welcome to use laptops in the class but only for legitimate class-related purposes.
Please be respectful of others and keep sound muted. No extracurricular internet-related activities are
permitted during class.
Cell phones: It is understood that students may need to leave phones on to receive emergency
notifications but sound must be turned off. If your phone audibly rings during class, you will be asked to
answer it in front of the class; in the event of repeated cell phone disruptions during class, the instructor
reserves the right to speak with the caller. Phones must be put away during exams; if a phone is
observed during an exam, you will be asked to turn in your exam and you will not be permitted to
complete it.
Food and beverage: We are meeting 9:45 – 11:00. You are welcome to bring your breakfast, brunch,
and/or something to drink but please be respectful of others.
Syllabus Updates
The syllabus is subject to change based on the needs of the class and the pace of the instructor.
Changes will be announced in class and the syllabus will be updated on the course website in Canvas.
Date
8/25
Day
Tu
8/27
Th
Topic
Introduction and basic
principles
Basic principles and diagnostics
Specifics
Intro to class & local, national, global health
concerns, basic principles
9/1
Tu
Immunology I
9/3
Th
Immunology II
Classification of organisms, diagnostics
Host protective responses and innate
immunity
Cellular immunity
Quiz 1
Quiz 2
9/8
Tu
Immunology III
Humoral Immunity
9/10
Th
Immunology IV
Pathogen specific responses
Quiz 3
9/15
Tu
Exam #1
9/17
Th
Bacteriology - Pathogenesis
Pathogenesis, diagnosis & role in disease
Assign
Project
9/22
Tu
Staph, Strep, Entero
9/24
Th
Enteric bacteria
9/29
Tu
Respiratory Bacteria
10/1
Th
Sexually transmitted bacteria
Staphylococcus, Streptococcus,
Enterococcus
Salmonella, Campylobacter, Shigella, E coli,
Vibrio, Yersinia, Listeria, Helicobacter,
Bacillus
Corynebacterium, Pseudomonas,
Mycobacteria, Haemophilus, Legionella,
Mycoplasma
Neisseria, Haemophilus, Chlamydia,
Treponema
10/6
Tu
Outbreak Investigation
Paige Bordwine
10/8
Th
Spirochetes
10/13
Tu
10/15
Th
Borrelia, Leptospira
Brucella, Bartonella
Nammalwar Sriranganathan
Coxiella, Francisella, Rickettsia, Orientia,
Ehrlichia
10/20
Tu
Zoonotic and Vector-borne
bacteria
Zoonotic and Vector-borne
bacteria
Exam #2
10/22
Th
Group Exercise
10/27
Tu
Virology - Pathogenesis
Pathogenesis, diagnosis & role in disease
10/29
Th
DNA Viruses I
Papilloma, Polyoma, Adeno, Pox
11/3
Tu
Childhood exanthems
Parvo, Herpes, Paramyxo, Toga
11/5
Th
Respiratory viruses
Picorna (Rhino), Corona, Orthomyxo
11/10
Tu
GI Viruses
Picorna (Polio), Noro, Reo, HIV
11/12
Th
Hepatitis and HIV
Hepatitis, HIV
Quiz 10
11/17
Tu
Hemorrhagic viruses
11/19
11/24
Th
Tu
NS Viruses and prions
Thanksgiving Break
Arena, Bunya, Filo, Flavi
Rhabdo, Flavi, Toga (Alpha), Arena, prions
Quiz 11
11/26
Th
Thanksgiving Break
12/1
Tu
Presentations
12/3
Th
Presentations
12/8
Tu
Presentations
12/10
Th
No Class
Reading Day
12/11
Fri
Final Exam
7:45-9:45
Quiz 4
Quiz 5
Quiz 6
Quiz 7
Quiz 8
Quiz 9
Quiz 12