Download curriculum vitae - Jack Puymirat

CURRICULUM VITAE
NAME
JACK PUYMIRAT
ADDRESS
Unit of Human Genetics
CHUL Research Center
CHUQ - CHUL
2705 boul. Laurier, Ste-Foy, Québec G1V 4G2
TITLE
Internist in medicine, Paris
Doctor in medicine (M.D.)
Neurologist
Doctor in Sciences of Paris VI University (Ph.D.)
CURRENT
POSITION
Professor, Department of Medicine, Laval University, Quebec, Canada
Director of the Unit of Human Genetics, CHUL Research Center, Quebec,
Canada
Scientific director of the Molecular Diagnosis Laboratory, CHUL, Quebec,
Canada
Neurologist: Clinic of neuromuscular diseases at IRDPQ and CHUL.
EDUCATION
Baccalaureat
1969 :
Série E Academy of Limoges
Medical Education
1971 - 1975 : Faculty of Medicine Pitié-Salpétrière: Paris, France
1983 :
M.D. Medicine thesis, Laureate of Faculty of Medicine of
Paris, France
Internship
1975 - 1981 :
1986 :
Speciality of Neurology, Paris France
Licence of Neurology, Paris, France
Scientific Education
1975 - 1977 : University of Pierre and Marie Curie - Paris VI, Paris, France.
Licence of Biochemistry and Metabolism
1977-1978:
DEA in Neurobiology
1981 - 1986 : Collège de France, University of Paris VI, Paris, France
Ph.D.
EXPERIENCE
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1999-present : Unit of Human Genetics, CHUL Hospital, Quebec, Canada Laval
University Quebec, Canada
Professor of Medicine, University of Laval
Puymirat, J.
1989 - 1999:
Unit of Genetic and Molecular Medicine, CHUL Hospital,
Laval University Quebec, Canada
Associated professor, University of Laval
1988 - 1989:
Laboratory of Cellular Neuroendocrinology, Collège de France,
Paris, France
Junior researcher INSERM
1986 - 1988:
Unit of Genetic and Molecular Medicine, Pr. J. Dussault, CHUL
Hospital, Quebec, Canada
Fellowship of FRSQ
Associated Professor, University of Laval
1982 - 1986:
Sce of Neurology, Hospital Sainte-Anne, Paris
Associated professor of Neurology
1979 - 1986 :
Laboratory of Cellular Neuroendocrinology, Collège de France,
Paris, France
Junior researcher INSERM
1976 - 1978:
Laboratory of Dr Y. Agid , Hospital of Salpétrière, Paris, France
Non remunerated searcher
1976:
Laboratory of Neuropharmacology of Pr J. Glowinski
Under instruction
1975 - 1976 :
Military Service, France
DIRECTION OF STUDENTS
- Director of DERBH diploma
Mme C. Fallet-Bianco, University of Paris VI, 1986 - 1989
- Director trainees :
1994 - … : 28
- Director master students :
1990 - … : 12
- Director Ph.D. students :
1986 - … : 8
- Director post-doctorat trainees :
1991 - … : 5
JURY POUR THESES DE DOCTORAT
1985 - … : 12
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Puymirat, J.
TEACHING
- Program of Neurobiology for PhD students
- Neurological Program for MD students at University Laval.
ORGANIZING FOR MEETINGS
- Member of the organizing committee of the XVth Meeting of the French Society of Experimental
Neuroendocrinology, Gif/Yvette, France, 1985.
- Responsible of the National Neurosciences expositions for the 20-years of INSERM, Paris,
1984.
- Responsible of CNRS Exposition, Paris, 1984.
- IDMC-05 International Myotonic Dystrophy Consortium –Quebec City Oct 2005 Head
organizer
AWARD
- National Dr David Green Award by Muscular Dystrophy Canada, June 2006
SOCIETIES
- Member of " French Society of Experimental Neuroendocrinology " 1986 - …
- Member of "Bureau du Cercle de neuroendocrinologie de L'Ile de France", (1984 - 1986)
- Member of "Bureau scientifique du groupe d'étude sur l'involution cérébrale" (1982- 1986)
- Member of "The Endocrine Society", 1990 - …
- Member of " The American Thyroid Association", 1990
- Member of "Club de recherches cliniques du Québec" 1989 - …
PUBLICATIONS
1.
Dupré N, Chrestian N, Bouchard JP, Rossignol E, Brunet D, Sternberg D, Brais B,
Mathieu J, Puymirat (2008) : J. Clinical, electrophysiologic, and genetic study of nondystrophic myotonia in French-Canadians. Neuromuscul Disord. 2008 Mar 10;
2.
Bernard G, Poulin C, Puymirat J, Sternberg D, Shevell M. (2008): Dosage Effect of a
Dominant
CLCN1
Mutation:
A
Novel
Syndrome.
3.
Yadava RS, Frenzel-McCardell CD, Yu Q, Srinivasan V, Tucker AL, Puymirat J,
Thornton CA, Prall OW, Harvey RP, Mahadevan MS. (2008) : RNA toxicity in
myotonic
muscular
dystrophy
induces
NKX2-5
expression.
4.
Meijer, IA., Dion, P., Laurent, S., Dupre, N., Brais, B., Levert, A., Puymirat, J., Rioux,
MF., Sylvain, M., Zhu, PP., Soderblom, C., Stadler, J., Blasckstone, C. Rouleau,
GA.(2007) : Characterization of a novel SPG3A deletion in a French-Canadian family.
ANM Neurolo
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Puymirat, J.
5.
Pelletier, R., Caron, S., Puymirat, J. (2006) : RNA based gene therapy for dominantly
inherited diseases. Current Gene Therapy 6,131-146
6.
Arsenault, ME., Prévost, C., Lescault, A., Laberge, C., Puymirat, J., Mathieu, J. (2006) :
Génotype-phenotype correlation study in DM1 patients with small CTG expansions.
Neurology 66, 1248-1250
7.
Chrestian, N., Puymirat, J. JP Bouchard Dupré, N. (2006) : Myotonia congenita, a cause
of muscle weakness and stiffness. Neurology 2, 1-7
8.
Langlois MA, Boniface C, Wang G, Alluin J, Salvaterra PM, Puymirat J, Rossi JJ, Lee
NS. (2005) Cytoplasmic and nuclear retained DMPK mRNAs are targets for RNAi in
myotonic dystrophy cells. J Biol Chem. 280, 1649-1654
9.
Kim, DH., Langlois, MA, Lee, Puymirat, J., Riggs, AD., Rossi, JJ.(2005) : HnRNP H
inhibits nuclear export of mRNA containing expanded CUG repeats and distal branch
point sequence. Nuclear Acid Research 33, 3866-3874
10.
Furling, D., Doucet, G., Langlois, M.A., Timchenko, L., Bélanger, E., Cossette. L. and
Puymirat, J. (2003) Viral vector producing antisense RNA restores myotonic dystrophy
myoblast functions. Gene Therapy 10, 795-802
11.
Langlois, M.A., Lee, N.S., Rossi, J.J. and Puymirat, J. (2003) Hammerhead ribozymemediated destruction of nuclear foci in mu0tonic dystrophy myoblasts. Molecular
Therapy. 7(5), 670-680
12.
Cayrou, C., Denver, R.J. and Puymirat, J. (2002) Suppression of BTEB in brain neuronal
cultures inhibits thyroid hormone-induced neurite branching. Endocrinology. 143/6,
2242-2249
13.
Brisson D., Tremblay M, Prévost C, Laberge C, Puymirat J, Mathieu J (2002) : Sibship
stability of genotype and phenotype in myotonic dystrophy. Clin, Genet, 62 : 220-225
14.
Martel, J., Cayrou C, Puymirat, J., (2002) Identification of new thyroid hormone regulated
genes in the development brain by CDNA microarray. NeuroReport 13, 1849-1851
15.
Dupré, N., Cossette, L., Hand, C.K., Bouchard, J.P., Rouleau, G.A. and Puymirat, J.
(2001) A founder mutation of french-canadian families with X-linked hereditary
neuropathy. Can. J. Neurol. Sci. 28 : 51-55
16.
Heyer, E, Zierkiewicz, E, Rochowski, V, Puymirat, J and Labuda, D. (2001) Phylogenetic
and familial estimates of mitochondrial substitution rates : study of control region
mutations in deep-rooting pedigrees. Am. J. Hum. Genet. 69 (5): 1113-1126
17.
Furling, D., Lemieux, D., Taneja, K. et Puymirat, J. (2001) Decreased levels in DMPK is
associated with a delay of human myotonic dystrophy myoblast differenciation. Neuro.
Musc. Disorders Nov ; 11 (8) : 728-35
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Puymirat, J.
18.
Castanotto D, Li J.R., Michienzi A, Langlois M.A., Lee N.S., Puymirat J, Rossi, J.J.
(2001) : Intracellular ribozyme applications. Biochem Soc Trans ; 30(6), 1140-1145
19.
Vilquin, J.-T., Guérette, B., Puymirat, J., Yaffe, D., Tomé, F. M.S., Fardeau, M. Fiszman,
M., Schwartz, K. and Tremblay, J.P. (1999) Myoblast transplantations lead to the
expression of the laminin 2 chain in normal and dystrophic (dy/dy) mouse muscles.
Gene Therapy 6: 792-800.
20.
Puymirat, J., Ouellet, L., Baas, D. and Sarliève, L.L. (1999) BTEB : Un facteur de
transcription qui pourrait jouer un rôle dans l’effet de la triiodothyronine (T3) sur
l’élongation neuritique. Médecine/Sciences 15: II-III.
21.
Dupré, N., Bouchard, J.-P., Brunet, D., Vanasse, M., Lemieux, B. and Puymirat, J. (1999)
Clinical and electrophysiological study in French-Canadian population with CharcotMarie-Tooth disease type 1A associated with 17p11.2 duplication. Can. J. Neurol. Sci.
26: 196-200.
22.
Denver, R.J., Ouellet, L., Furling, D., Kobayashi, A., Fujii-Kuiyama, Y. and Puymirat, J.
(1999) Basic transcription element binding protein (BTEB) is a thyroid hormoneregulated gene in the developing central nervous system: Evidence for a role in neurite
outgrowth. J. Biol. Chem.274: 23128-23134.
23.
Furling, D., Marette, A. and Puymirat, J. (1999) Insulin-like growth factor-I circumvents
defective insulin action in human myotonic dystrophy skeletal muscle cells.
Endocrinology 140: 4244-4250.
24.
Skuk, D., Furling, D., Bouchard, J.-P., Goulet, M., Roy, B., Lacroix, Y., Vilquin, J.T.,
Tremblay, J.-P. and Puymirat, J. (1999) Transplantation of human myoblasts in SCID
mice as a potential muscular model for myotonic dystrophy. J. Neuropathol. & Exper.
Neurol. 58: 921-931.
25.
Etongué-Mayer, P., Faure, R., Bouchard, J.-P. and Puymirat, J. (1998) Characterization of
a 54-kDa Human Protein Kinase recognized by an antiserum raised against the
myotonin kinase. Muscle & Nerve 21(1): 8-17.
26.
Baas, D., Puymirat, J. and Sarliève, L.L. (1998) Posttranscriptional regulation of
oligodendroglial thyroid hormone (T3) receptor 1 by T3. Intern. J. Develop. Neurosci.
16(6): 461-467.
27.
Baas, D., Bourbeau, D., Sarliève, L-L., Ittel, M.-E., Dussault, J.H. and Puymirat, J. (1997)
Oligodendrocyte maturation and progenitor cell proliferation are independently
regulated by thyroid hormone. Glia 19: 324-332.
28.
Deschênes, I., Chahine, M., Tremblay, J., Paulin, D. and Puymirat, J. (1997) Increase in
the proliferative capacity of human myoblasts by using the T antigen under the
vimentin promoter control. Muscle & Nerve 20: 437-445.
29.
Bouchard Cl., Allard P., Mercier P., St-Laurent M., Dussault J.H. and Puymirat J. (1997)
Sensibilité et spécificité du dosage de la thyréostimuline (TSH) sur papier filtre pour le
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Puymirat, J.
diagnostic d'hypothyroïdie chez la personne âgée. Annales d'Endocrinologie 58: 152157.
30.
Puymirat, J. (1997) Are thyroid hormone receptors sufficient for transcription ? Endocrine
News, Bulletin August.
31.
Nobrega, J.N., Raymond, R., Puymirat, J., Belej, T. and Joffe, R.T. (1997) Regional
changes in betal thyroid hormone receptor immunoreactivity in rat brain after
thyroidectomy. Brain Res. 761: 161-164.
32.
Heyer, E., Puymirat, J., Dieltjes, P., Bakker, E. and De Knijff, P. (1997) Estimating Ychromosome-specific microsatellite mutation rates using deep rooting pedigrees.
Human Mol. Gen. 6(5): 799-803.
33.
Trépanier, G., Furling, D., Puymirat, J. and Mirault, M-E. (1996) Immunocytochemical
localization of Seleno-glutathione peroxidase in the adult mouse brain. Neuroscience
75: 231-243.
34.
Puymirat, J. (1996) Thyroid hormone receptors are necessary but not sufficient for
transcription: an invited commentary. Eur. J. Endocrinol. 135: 651-652.
35.
Puymirat, J., Étongué-Mayer, P. and Dussault, J.H. (1995) Thyroid hormones stabilize
acetylcholinesterase mRNA in neuro-2A cells that overexpress the 1 thyroid receptor.
J. Biol. Chem. 270 (51): 30651-30656.
36.
Guérette B., Roy R., Tremblay M., Asselin I., Kinoshita I., Puymirat J. and Tremblay, J.P.
(1995) Increased granzyme B mRNA following alloincompatible myoblast
transplantation. Transplantation 60 (9): 1011-1016.
37.
Etongué-Mayer, P., Faure, R., Bouchard, J.-P., Thibault, M.-C. and Puymirat, J. (1994)
The myotonin-protein kinase phosphorylates tyrosine residues in normal human
skeletal muscle. Biochem. Biophys. Res. Comm. 199: 89-92.
38.
Besnard, F., Luo, M., Miehe, M., Labourdette, G., Dussault, J.H., Puymirat, J. and
Sarliève, L.L. (1994) Transient expression of 3,5,3'-triiodothyronine nuclear receptors
in rat oligodendrocytes in vivo and in vitro immunocytochemical studies. J. Neurosci.
Res. 37: 313-323.
39.
Lebel, J-M., Dussault, J.H. and Puymirat, J. (1994) Overexpression of the 1 thyroid
receptor induces differentiation in neuro-2a cells. Proc. Natl. Acad. Sci., 91: 26442648.
40.
Baas, D., Fressinaud, C., Ittel, M.E., Reeber, A., Dalençon, D., Puymirat, J. and Sarliève,
L.L. (1994) Expression of thyroid hormone receptor isoforms in rat oligodendrocyte
cultures. Effect of 3,5,3'-triiodo-L-thyronine. Neurosci. Letters 176(1): 47-51.
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41.
Baas, D., Bourbeau, D., Carré, J.L., Sarliève, L.L., Dussault, J.H. and Puymirat, J. (1994)
Expression of  and  thyroid receptors during oligodendrocyte differentiation.
Neuroreport 5:1805-1808.
42.
Lezoualch, F., Hassan, A., AbdelTowab, H., Puymirat, J. and Demeneix, B.A. (1994)
Precocious auto-induction of thyroid hormone receptors in embryonic chick
hypothalamic neurons. Neurosci Lett. 180: 197-202.
43.
Puymirat, J., Cossette, L., Gosselin, F. and Bouchard, J.-P. (1994) Red blood cell Cu/Zn
superoxide dismutase activity in sporadic amyotrophic lateral sclerosis. J. Neurol. Sci.
127:121-123.
44.
Mirault, M.E., Tremblay, A., Furling, D., Trepanier, G., Dugre, F., Puymirat, J. and
Pothier, F. (1994) Transgenic glutathione peroxidase mouse models for neuroprotection
studies. Ann. N.Y. Acad. Sci. 738: 104-115.
45.
Graff, M.N., Baas, D., Puymirat, J., Sarliève, L.L. and Delaunoy, J.P. (1993) The  and 
thyroid receptors are expressed by cultured ependymal cells. Correlation with the effect
of L-T3 on glutamine synthetase mRNAs. Neurosciences Letters 150: 174-178.
46.
Barakat-Walter, I., Duc, C. and Puymirat, J. (1993) Changes of nuclear 3,5,3'triiodothyronine receptors expression in dorsal root ganglia and sciatic nerve during
development: comparison with regeneration. Europ. J. Neurosc. 5: 319-326.
47.
Labelle, Y., Puymirat, J. and Tanguay, R.M. (1993) Localization of cells in the rat brain
expressing fumarylacetoacetate hydrolase, the dificient enzyme in heredity tyrosinemia
type 1. B.B.A. 1180: 250-256.
48.
Lebel, J.M., L'Héreault, S., Beaudoin, N., Dussault, J.H. and Puymirat, J. (1993) Thyroid
hormone up-regulates thyroid hormone receptor
gene expression in rat cerebral
hemisphere astrocyte cultures. Glia. 9:105-112.
49.
Ardail, D., Lerme, F., Puymirat, J. and Morel, G. (1993) Evidence for the presence of and
-related T3 receptors in rat liver mitochondria. Europ. J. Cell Biology 62: 105-113.
50.
Puymirat, J., Marchand, R., Dussault and J.H. (1992) Immunocytochemical localization of
 thyroid receptor in the adult rat cerebellum. Neurosc. Lett. 135: 239-242.
51.
Barakat-Walter, I., Duc, C., Sarliève, L.L., Puymirat, J., Dussault, J.H. and Droz, B. (1992)
The expression of nuclear 3,5,3'-Triiodothyronine receptors is induced in Schwann
cells by nerve transection. Exp. Neurol. 116(2): 189-197.
52.
Puymirat, J.: Thyroid receptor in the rat brain. (1992) Progress in Neurobiol. 39: 281-294.
53.
Puymirat, J., L’Hérault, S. and Dussault, J.H. (1992) Expression of thyroid hormone
receptors mRNAs in cerebral hemisphere neuronal cultures. Devel. Brain Res. 69:173177.
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54.
Puymirat, J., Miehe, M., Marchand, R., Sarliève, L. and Dussault, J.H. (1991)
Immunocytochemical localization of thyroid hormones receptors in the adult rat brain.
Thyroid 1(2): 173-184.
55.
Puymirat, J., Gadbois, P., Dussault, L., Garceau, L. and Dussault, J.H. (1991) Production
of a specific polyclonal antibody against the rat thyroid using synthetic peptide as
antigen. Acta Endocrinologica 125: 397-400.
56.
Garza, R., Puymirat, J. and Dussault, J.H. (1990) Immunocytochemical localization of
thyroid hormone nuclear receptors in cultured acetylcholinesterase-positive neurons: a
correlation between the presence of thyroid hormone nuclear receptors and Ltriiodothyronine morphological effects. Neuroscience 36: 473-483.
57.
Garza, R., Puymirat, J. and Dussault, J.H. (1990) Influence of soluble environmental
factors on the development of fetal brain acetylcholinesterase-positive neurons cultured
in a chemical defined medium: Comparison with the effects of L-triiodothyronine (LT3). Dev. Brain Res. 56: 160-168.
58.
Puymirat, J., Luo, M. and Dussault, J.H. (1989) Immunocytochemical localization of
thyroid hormone nuclear receptors in cultured hypothalamic dopaminergic neurones
using a monoclonal antibody against rat liver nuclear thyroid hormone receptor.
Neuroscience 30: 442-449.
59.
Luo, M., Puymirat, J. and Dussault, J.H.. (1989) Immunocytochemical localization of
nuclear triiodothyronine receptors in astrocyte cultures. Dev. Brain Res. 46: 131-136.
60.
Gueguen, B., Puymirat, J., Grouselle, D., Piketty, M.L., Bleton, J.P., Bourdel, M.C. and
Rondot, P. (1988) Effets cliniques, électrophysiologiques et endocriniens de la TRH en
perfusion à doses élevées dans la sclérose latérale amyotrophique. Revue de Neurologie
144: 704-709.
61.
Garza, R., Dussault, J.H. and Puymirat, J. (1988) Influence of triodothyronine on the
morphological and biochemical development of fetal brain acetylcholinesterasic
neurons cultured in a chemically defined medium. Dev. Brain Res. 43: 287-297.
62.
Puymirat, J., Barret, A., Faivre-Bauman, A. and Tixier-Vidal, A. (1987) Biochemical
characterization of the uptake and the release of 3H-DA by hypothalamic dopaminergic
neurons cultured in serum-free-medium. Develop. Biol. 119: 75-84.
63.
Puymirat, J. (1987) Controle hormonal de la différenciation des neurones hypothalamiques
en culture cellulaire. Ann. Endocrinol. 48: 352-355.
64.
Gomez, S., Davous, P., Rondot, P. and Puymirat, J. (1986) Somatostatin like
immunoreactivity and acetylcholinesterase activity in the cerebro spinal fluid of
patients with Alzheimer disease. Psychoneuroendocrinology 1: 69-73.
65.
Gomez, S., Puymirat, J., Valade, D., Davous, P., Rondot, P. and Cohen, P. (1986) Patients
with Alzheimer's disease show an increased content of 15KD somatostatin precursor
and lowered level of tetradecapeptide in their cerebrospinal fluid. Life Science 39: 7.
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66.
Couchy, D., Faivre-Bauman, A., Puymirat, J., Tixier-Vidal, A. and Nunez, J. (1986)
Expression of microtubules-associated proteins during the early stages of neurites
extension by brain neuron cultures in defined medium. J. Neurochem. 47: 1255-1261.
67.
Puymirat, J. and Faivre-Bauman, A. (1986) Evolution of triiodothyronine nuclearbinding
site in hypothalamic serum-free culture: evidence for their presence in neurons and
astrocytes. Neurosc. Letters 68: 299-304.
68.
Puymirat, J. (1985) Effect of dysthyroidism on central catecholaminergic neurons.
Neurochem. Intern. 7: 969-977.
69.
Koubesserian, P., Davous, P., Bianco, C., Puymirat, J., Fontaine, C., De Recondo, J. and
Rondo, P. (1985) Familial dementia of the Newmann type (subcortical gliosis). Revue
de Neurologie 161: 706-712.
70.
Puymirat, J., Faivre, A., Barret, A., Loudes, C. and Tixier-Vidal, A. (1985) Does
triiodothyronine influence the differentiation of fetal mouse mesencephalic
dopminergic neurons cultured in serum free medium? Dev. Brain. Res. 23: 315.
71.
Faivre, A., Puymirat, J., Loudes, C., Barret, A. and Tixier-Vidal, A. (1984) Laminin
promotes attachment and neurites elongation of fetal hypothalamic neurons grown in
serum free medium. Neurosci. Letters 44: 83-89.
72.
Bourre, J.M., Faivre-Bauman, A., Dumont, O., Nouvelot, A., Loudes, C., Puymirat, J. and
Tixier-Vidal, A. (1983) Influence de la supplémentation en acides gras polyinsaturés de
milieux de culture sur la morphologie et la composition des cultures de cellules foetales
de cerveau de souris. C.R. Acad. Sci. 296: 629.
73.
Bourre, J.M., Faivre, A., Dumont, O., Nouvelot, A., Loudes, C., Puymirat, J. and TixierVidal, A. (1983) Effect of polyunsaturated Fatty acids on fetal mouse brain cells in
culture in a chemically defined medium. J. Neurochem. 41: 1234.
74.
Loudes, C., Faivre, A., Barret, A., Grouselle, D., Puymirat, J. and Tixier-Vidal, A. (1983)
Release of immunoreactive TRH in serum free cultures of mouse hypothalamic cells.
Dev. Brain Res. 9: 231-240.
75.
Puymirat, J., Barret, A., Picart, R., Vigny, A., Loudes, C., Faivre, A. and Tixier-Vidal, A.
(1983) Triiodothyronine enhances the morphological maturation of dopaminergic
neurons from fetal mouse hypothalamus cultured in serum free medium. Neurosci. 10:
801-810.
76.
Puymirat, J., Faivre, A., Bizzini, B. and Tixier-Vidal, A. (1982) Pre and post natal
ontogenesis of neurotransmitter synthetising enzymes and 125I-Tetanus toxin binding
capacity in the mouse hypothalamus. Dev. Brain Res. 3: 199-206.
77.
Faivre, A., Rosenbaum, E., Puymirat, J., Grouselle, D. and Tixier-Vidal, A. (1981)
Differentiation of fetal mouse hypothalamic cells in serum free medium.
Developmental Neurosciences 4: 118.
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78.
Faivre, A., Rosenbaum, E., Puymirat, J. and Tixier-Vidal, A. (1980) Mise en évidence
d'activités neuronales dans des cultures primaires d'hypothalamus de souris foetales
maintenues en milieu sans sérum. C.R. Acad. Sci., Paris, 290: 885-887.
79.
Puymirat, J., Javoy,, F., Gaspa P., Ploska, A., Prochiantz, A. and Agid, Y. (1979) Postmortem stability and storage in the cold of brain enzymes. J. Neurochem. 32: 449-454.
BOOK CHAPTERS
1.
Dupré, N., Bouchard, J.-P., Cossette, L., Brunet, D., Vanasse, M., Lemieux, B., Mathon,
G. and Puymirat, J. (1999) Phenotypic manifestations in French-Canadian Populations
with Charcot-Marie-Tooth Disease Type 1A Associated with 17p11.2 Duplication. In:
Annals of the New York Academy of Sciences "Charcot-Marie-Tooth Disorders". M.E.
Shy, J. Kamholz et R.E. Lovelace (Eds), 497-499.
2.
Puymirat, J. (1997) Functions of thyroid hormone receptors in prenatal rat brain
development. In: "Recent Res. Dev. Neuroendo. - Thyroid Hormone and Brain
Maturation", 103-111.
3.
Dussault, J.H., Glorieux, J., Puymirat, J., Van Vliet, G., Roy, J. and Doyon, J. (1994)
Intellectual and neurological development of children age 12 and 15 with congenital
hypothyroidism detected by neonatal screening. In: The damaged brain of iodine
deficiency. John B. Stanbury, (Ed), 149-151.
4.
Puymirat, J., Dussault, L., Schmidt, E.D.L.S. and Dussault, J.H. (1991)
Immunocytochemical localization of thyroid receptors in brain cell cultures, using three
different specific antibodies. In: "Progress in Thyroid Research". A. Gordon, J. Gross
and G. Hennemann (Eds), 879 -881.
5.
Dussault, J.H., L’Hérault, S. and Puymirat, J. (1991) Expression of
and
thyroid
hormone receptor mRNAs in cultured rat cerebral hemisphere neurons. In: "Progress in
Thyroid Research". A. Gordon, J. Gross and G. Hennemann (Eds), 883-885.
6.
Sarliève, L., Besnard, C., Yusta, B., Pascual, A., Aranda, A., Luo, M., Dussault, J.H. and
Puymirat, J. (1989) Investigation of myelinogenesis in vitro: Transient expression of LTriiodothyronine nuclear receptors in secondary cultures of pure rat oligodendrocytes.
In: "Iodine and the Brain". R. Delong and J. Robbins, (Eds) Plenum Press, New York,
113-130.
7.
Puymirat, J. and Rondot, P. (1986) Study of biological markers in the cerebrospinal fluid
in Alzheimer’s disease.. "Journées de Neurologie". Dohme and Chibret, (Eds).
CV page 10 de 30
Puymirat, J.
8.
Gomez, S., Davous, P., Faivre, A., Rondot, P., Valade, D. and Puymirat, J. (1986)
Acetylcholinesterase activity and somatostatin like immunoreactivity in the cerebro
spinal fluid of demented patients. In: "Advances in behavorial Biology" Alzheimer and
Parkinson disease: Strategies and developmental therapeutics. Fisher, A., Hanin, I. and
Lachman, S. (Eds) Plennum Press, 317-322.
9.
Puymirat, J., Barret, A., Blanc, G., Faivre, A., Loudes, C. and Tixier-Vidal, A. (1985)
Effects of thyroid hormones on the development of mouse hypothalamic dopaminergic
neurons. In: "Fetal Neuroendocrinology". Ellendorff F., Gluckman, P.D. and Parvizi,
N. (Eds) Perinatalogy Press, 121-127.
10.
Faivre-Bauman, A., Puymirat, J., Loudes, C. and Tixier-Vidal, A. (1984) Differentiated
mouse hypothalamic cells in serum free medium. In: "Cell Culture Methods for
Molecular and Cell Biology", vol.4, Methods for serum-free culture of neuronal and
lymphoid cells. Barnes, D.W., Sirbasku, S.A. and G. Sato, G.H., A. R. Liss, (Eds) New
York, 37-56.
11.
Ziegler, M. and Puymirat J. (1983) Les neuropeptides. "Confrontations psychiatriques" 22:
205-235.
12.
Loudes, C., Faivre, A., Puymirat, J. and Tixier-Vidal, A. (1983) Effects of hormones on
the development of mouse fetal hypothalamic neurons in vitro. In: "Drugs and
Hormones in Brain Development" Schlumpf, M. and Lichtensteiger W. (Eds)
Monograph in neural Sciences, Karger, Basel, 9, 43-49.
13.
Puymirat, J., Loudes ,C., Faivre, A., Bourre, J.M. and Tixier-Vidal, A. (1982) Expression
of neuronal function by mouse fetal hypothalamic cells cultured in hormonally defined
medium. Cold Spring Harbor Conferencees on cell proliferation. In: "Growth of cells in
hormonally defined media". vol.9, D. Sirbasku and G. Sato, (Eds) 1033-1051.
14.
Tixier-Vidal, A., Faivre-Bauman, A., Puymirat, J., Rosembaum, E. and Grouselle, D.
(1981) Expression of neuronal activities in cultures of dissociated fetal mouse
hypothalamic cells. Effects od hormones as studied in serum-free medium. In: "Adv.
Physiol. Sci., vol.14, Endocrinology, Neuroendocrinology, Neuropeptides II". E. Stark,
G.B., Makara B., Halasz and Rappai, (Eds) Pergamon press, 101-105.
INVITED SPEAKER
1.
Congrès International de myologie 2005
Nantes , France, Mai 2005
Rna-based gene therapy for dominantly inherited diseases: the example of myotonic
dystrophy
2.
Conférence, Pitié-Salpetière Hospital
France, June 2004
Thérapie génique pour la dystrophie myotonique
CV page 11 de 30
Puymirat, J.
3.
Conférence, Service de génétique, Hôpital de Bordeaux
France, September 2004
Dystrophy myotonique : de la clinique à la thérapie
4.
Conférence, Laboratoire Animage-Creatis
Lyon, France, December 2004
Evaluation pré-clinique d’une thérapie génique pour la dystrophie myotonique
5.
Conférence Vect Euro Train
Towards clinical gene therapy : pre-clinical gene transfer assessment
Stratagems for the development of a gene therapy for dominant hereditary
neuromuscular diseases. Barcelona 2004
6.
4th International Conference on Unstable Microsatellites and Human Disease
Potential therapeutic tools for myotonic dystrophy
Banff 2004
7.
4th International Myotonic Dystrophy Consortium Meeting
A soluble factor produced by myotonic dystrophy myoblasts inhibits myogenic
differentiation.Glasgow 2003
8.
Annual Congress of ANLLF and ANQ
Development of a clinical grid for myotonic dystrophy.
France 2002
9.
Classification génétique des maladies neuromusculaires.
Département de pédiatrie, Québec, CHUQ-CHUL, 2001
10.
27th Meeting of European Thyroid Association Meeting
Suppression of BTEB in brain neuronal cultures inhibits thyroid hormone-induced
neurite branching. Poland 2001
11.
3rd International Myotonic Dystrophy Conference
Comparison of three methods for the extraction of mutant myotonic dystrophic protein
kinase mRNAs (DMPK mRNAs). Japan 2001
12.
Rôle des hormones thyroïdiennes sur la prolifération et la différentiation des cellules
nerveuses. Conférence du département d’endocrinologie, Sherbrooke, March 1998.
13.
Dystrophie myotonique.
Département de Neurologie, Limoges, France, 1998.
14.
Hormones thyroïdiennes et SNC.
Université Ann Arbor, Michigan, 1997.
15.
Rôle du récepteur b1 aux hormones thyroïdiennes dans la différentiation neuronale.
CHU Sherbrooke, 1994.
16.
L'expression des récepteurs aux hormones thyroïdiennes et fonction du SNC.
CV page 12 de 30
Puymirat, J.
Université McGill, Département de Pharmacologie Thérapeutique, Montréal, 1994.
17.
Récepteurs aux hormones thyroïdiennes au cours du développement du SNC. CHU
Sherbrooke, Québec, 1992.
18.
Conference de La Société des neurosciences françaises
Implication des récepteurs b1 dans les neurones acétylcholinestérase du SNC.
Strasbourg, France, 1992.
19.
Mécanismes d'action des hormones thyroïdiennes dans le développement du SNC.
Hôtel-Dieu, Québec, Avril 1991
20.
Mécanismes d'action des hormones thyroïdiennes dans le développement du SNC. CHU
Laval, Québec, Novembre 1990.
21.
Étude des récepteurs aux hormones thyroïdiennes au cours du développement du SNC.
Laboratoire Ben Ari U29 INSERM), Paris, 1989.
22.
Récepteurs aux hormones thyroïdiennes au cours du développement du SNC. Collège de
France, Paris, 1989.
23.
Étude des récepteurs aux hormones thyroïdiennes au cours du développement du SNC.
Institut Pasteur, Paris, France, 1989.
24.
Étude des récepteurs aux hormones thyroïdiennes au cours du développement du SNC..
Interrelation avec les produits erbA. Centre de Neurochimie, Strasbourg, France, 1989.
25.
Étude des récepteurs aux hormones thyroïdiennes au cours du développement du SNC..
Club de thyroïde de Québec, Ste-Adèle, Québec, Octobre 1989.
26.
Étude in vitro du rôle de la L-T3 dans la maturation neuronale. CHU Sherbrooke 1987.
27.
Récepteurs des hormones thyroïdiennes dans le cerveau.
Département of Prof. Rapport, Hôpital Neker, Paris, 1986.
28.
Intérêt de l'étude du LCR au cours du vieillissement.
The day of Neurology, Clermont-Ferrand, 1986.
29.
Rôle des hormones thyroïdiennes au cours du développement du SNC.. CHU Laval,
Quebec, 1986.
30.
Effets de la triiodothyronine sur les neurones hypothalamiques dopaminergiques.
Université de Ulm RFA, 1985.
31.
Influence des hormones thyroïdiennes
dopaminergiques chez la souris.
Université Laval, Québec, 1985.
32.
Intérêt des marqueurs du LCR dans la maladie d'Alzheimer.
CV page 13 de 30
sur
la
différenciation
des
neurones
Puymirat, J.
Démence du type Alzheimer, Paris, 1985.
33.
Influences des hormones thyroïdiennes sur l'activité des systèmes monoaminergiques
centraux. Collège de France dans le cadre des tendances actuelles en
neuroendocrinologie, 1984.
34.
Influence des hormones thyroïdiennes
hypothalamiques en culture.
Congrès : "Growth Factor", Paris, 1983.
35.
Intérêt des cultures de cellules nerveuses.
Département of Neurologie, Hôpital Sainte-Anne, Paris, 1983.
36.
Influence des hormones thyroïdiennes dans la différenciation des neurones
dopaminergiques de l'hypothalamus.
Institut Pierre et Marie Curie, Paris, 1983.
sur
le
développement
des
neurones
COMMUNICATIONS
1.
Child
Neurology
Society,
Pittsburgh,
18-21
octobre
2006
Titre: Dosage effect of a dominant CLCN1 mutation: A novel syndrome
G Bernard, C Poulin, J Puymirat and M Shevell
1
11th International Congress World Muscle
Bruges, Bruxelles, Octobre 2006
RNA based gene therapy for dominantly inherited of neuromuscular disorders
2.
European Muscle Conference
Heidelberg, Allemagne, September 2006
Therapeutic strategies for myotonc dystrophy
3.
5th International Myotonic Dystrophy Consortium
Quebec, Canada, October 2005
Characterization of myoblast cells from myotonic dystrophy type 2 patients
4.
5th International Myotonic Dystrophy Consortium
Quebec, Canada, October 2005
Intergenerational contraction of the CIG repeats
myotonicdystrophy
in
large
5.
5th International Myotonic Dystrophy Consortium
Quebec, Canada, Octobre 2005
A potential gene therapy for myotonic dystrophy type 1
6.
Annual Scientific Meeting of Canadian College of Medical Geneticists
Bromont, Canada, Octobre 2005
New therapeutic avenues for myotnic dystrophy
CV page 14 de 30
families
with
Puymirat, J.
7.
26th International Epilepsy Congress
Paris, France, Août 2005
8.
American Society for Gene Therapy 8th Annual Meeting
St-Louis, USA, Juin 2005
A database for managing neuromuscular disease data in the province of Quebec
9.
Congrès International de myologie 2005
Nantes , France, Mai 2005
A soluble factor produced by myotonic dystrophy myoblasts inhibits myogenic
differentiation.
10.
Congrès International de myologie 2005
Nantes , France, Mai 2005
A database for managing neuromuscular disease data in the province of Quebec
11.
Congrès International de myologie 2005
Nantes , France, Mai 2005
Rna-based gene therapy for dominantly inherited diseases: the example of myotonic
dystrophy
12.
Conférence, Laboratoire Animage-Creatis
Lyon, France, December 2004
Evaluation pré-clinique d’une thérapie génique pour la dystrophie myotonique
13.
Conférence, Service de génétique, Hôpital de Bordeaux
France, September 2004
Dystrophy myotonique : de la clinique à la thérapie
14.
Conférence , Genethon Institute
France, June 2004
Thérapie génique pour la dystrophie myotonique
15.
Conférence, Pitié-Salpetière Hospital
France, June 2004
Thérapie génique pour la dystrophie myotonique
16.
Réunion scientifique - CHUQ
Evaluation génétique des maladies neuromusculaires en 2004
24 mars 2004
17.
Conférence Vect Euro Train, Barcelona, February 2004
Stratagème pour le dévelopment d’une thérapie génique pour les maladies
neuromusculaires héréditaires.
Puymirat, J
18.
Service de Neurologie, Bordeaux, France, February 2004
Traitement de la dystrophie myotonique: de la pharmacologie à la thérapie génique
Puymirat, J.
CV page 15 de 30
Puymirat, J.
19.
4th International Conference on Unstable Microsatellites and Human Disease
Banff, Canada, February 2004
Potential therapeutic tools for myotonic dystrophy
20.
Rencontre du Réseau de Steinert , Paris January 2004
Puymirat, J
21.
31st Congress of SNE, Paris, Septembre 2003
Puymirat, J. : Rôle du récepteur thyroïdien 1 dans la différentiation du cervelet.
22.
32nd European Muscle Conference – EMC 2003, Montpellier, 7-10 Septembre 2003
Puymirat J. : Development of a therapeutical tool for myotonic dystrophy.
23.
CCNS 2003, June 2003, Quebec, Canada
Langlois, MA, Doucet, G, Rossi, J.J. and Puymirat J : Gene therapy for myotonic
dystrophy by preferential targeting of mutant myotonin protein kinase mRNA.
24.
6th Annual Meeting American Society for Gene Therapy, Juin 2003, Washington
Langlois, MA, Lee, N.S., Rossi, J.J. and Puymirat J : RNA-Based gene therapies for
myotonic dystrophy type 1.
25.
4th International Myotonic Dystrophy Consortium Meeting, Glasgow, April 2003
Puymirat J., Bélanger, E., Haineault, C., Beaulieu, D., and Doucet, G: A soluble factor
produced by myotonic dystrophy myoblasts inhibits myogenic differentiation.
26.
4th International Myotonic Dystrophy Consortium Meeting, Glasgow, April 2003
Haineault, C., Beaulieu, D., Furling, D. and Puymirat, J. : Expression of myogenic
regulatory factors in myotonic dystrophy (DM1) myoblasts.
27.
Congrès Neurosciences, 2003
Fournier, M, Noël, M, Cayrou, C, Puymirat, J, Mouginot, D and Mirault, M.E. : Thyroid
hormone-dependent differentiation of neuronal cells inhibited by methylmercury.
28.
MDA - Conférence de presse, Jan 2003, USA
Jack Puymirat : (S) Blocking excess genetic material - a new lead in NMD(T).
29.
Xth International Congress on Neuromuscular Disease, July 2002, Vancouver, Canada
Langlois MA, Doucet G, Timchenko L, Rossi JJ et Puymirat J : Stratagem in vitro for
gene therapy directed to myotonic dystrophy (DM1).
30.
Société Francophone de Thérapie Cellulaire et Génique, Juin 2002, Paris, France
Puymirat J et Langlois MA : Développement d'une thérapie génique pour la dystrophie
myotonique.
31.
4e Journées génétiques 2002, Montréal, May 2002 Dupré N, Bouchard J-P, Verreault S,
Rivest D, Puymirat J, Rouleau GA : A Recessive ataxia originating from the Beauce, a
new pure cerebellar ataxia.
CV page 16 de 30
Puymirat, J.
32.
4e Journées génétiques 2002, Montréal, May 2002 Puymirat J : Network for
neurogenetic diseases.
33.
4e Journées génétiques 2002, Montréal, May 2002 Langlois MA, Puymirat J :
Développement d'une thérapie génique pour la dystrophie myotonique.
34.
7e Annual Meeting of RNA Society, May 28th-June 2nd 2002, Wisconcin, USA Kim D,
Langlois MA, Puymirat J et Rossi J : Binding of hnRNP H (CUG)n expansions
associated with myotonic dystrophy.
35.
Annual Congress of ANLLF and ANQ, 2002, Cannes, France
Jack Puymirat. Development of a clinical grid for myotonic dystrophy
36.
Réunion des membres du Département des sciences neurologiques, Nov 2002, Qc
L'investigation des myopathies en 2002.
37.
73rd American Thyroid Association Meeting, Washington, USA, November 2001
Puymirat J. Cayrou C, Grouselle D, Martel J : A transgenic mouse expressing a mutant
(beta) thyroid hormone receptor show delay in cerebellar development.
38.
3rd International Myotonic Dystrophy Conference, Kyoto, Japan, October 2001
Cossette L, Doucet G and Puymirat J. Comparison of three methods for the extraction of
mutant myotonic dystrophic protein kinase mRNAs (DMPK mRNAs)
39.
3rd International Myotonic Dystrophy Conference, Kyoto, Japan, October 2001
Puymirat J, Doucet G, Cossette L and Timchenko L. The use of RNA antisense as a
potential gene therapy for myotonic dystrophy (DM).
40.
3rd International Myotonic Dystrophy Conference, Kyoto, Japon, Octobre 2001
Kim D, Langlois MA, Puymirat J and Rossi JJ. Identification of the CUG repeats
binding proteins in HeLa and myoblast.
41.
27th Meeting of European Thyroid Association Meeting, Août 2001, Warsaw, Poland
Puymirat J., Cayrou C and Martel J. : Mice with a targeted mutation in the thyroid 
receptor gene exhibit delayed development in the cerebellum.
42.
27th Meeting of European Thyroid Association Meeting, Août 2001, Warsaw, Poland
Puymirat J., Cayrou C and Martel J. : Suppression of BTEB in brain neuronal cultures
inhibits thyroid hormone-induced neurite branching.
43.
Journée de la Recherche, Faculté de Médecine, Université Laval, Québec, Juin 2001.
Puymirat, J. et Cayrou C. : Development of transgenic mice which reproduce brain
abnormalities observed in the hypothyroid state.
44.
Journée de la Recherche, Faculté de Médecine, Université Laval, Québec, Juin 2001.
Puymirat, J. et Martel J. : Identification of thyroid hormones target genes by microarray.
45.
4e colloque de l'Association de thérapie génique du Québec, Montréal, Juin 2001,
Puymirat J. : Gene therapy for myotonic dystrophy.
CV page 17 de 30
Puymirat, J.
46.
Journée de la Recherche, Faculté de Médecine, Université Laval, Québec, Mai 2000.
Dupré, N., Cossette, L., Bouchard, J.-P. and Puymirat, J.: Molecular diagnosis of the
Charcot-Marie-Tooth type 1A by PCR.
47.
Journée de la Recherche, Faculté de Médecine, Université Laval, Québec, Mai 2000.
Cayrou, C., Ouellet, L., Martel, J. and Puymirat, J.: Identification of thyroid hormones
target genes in the brain.
48.
Journée de la Recherche, Faculté de Médecine, Université Laval, Québec, Mai 2000.
Puymirat, J. and Furling, D.: Development of a gene therapy for myotonic dystrophy.
49.
International Congress of Myology (AFM), Acropolis, Nice, France, Mars 2000.
Furling, D. and Puymirat, J.: Differentiation of human myotonic dystrophy muscle cells
in vitro et in vivo.
50.
Fourth International Congress of the World Muscle Society, Talya Convention Centre,
Antalya, Turkey, Octobre 1999.
Skuk, D., Furling, D., Bouchard, J.-P., Vilquin, J.-T., Tremblay, J.P. and Puymirat, J.:
Human myoblast transplantation in SCID mice as a potential tool for studies in myotonic
dystrophy.
51.
68th Assemblée Annuelle - Collège Royal des Médecins et Chirurgiens du Canada,
Montreal, Septembre 1999.
Dupré, N., Cossette, L., Bouchard, J.-P. and Puymirat, J.: Comparison of tthree methods
for the molecular diagnosis of 1,5 MB duplication on chromosome 17 associated with the
Charcot-Marie-Tooth disease type 1A.
52.
72nd Annual Meeting of the American Thyroid Association, Palm Beach, Florida,
Septembre 1999.
Puymirat, J. and Denver, R.: Basic transcription element binding protein (BTEB) is a
thyroid hormone regulated gene in the developing brain: evidence for a role in neurite
outgrowth.
53.
Journée de la Recherche, Faculté de Médecine, Université Laval, Quebec, Mai 1999.
Furling, D., Marette, A. and Puymirat, J.: Effect of l’IGF-1 (Insulin-like growth factor-1)
on myotonic dystrophy skeletal muscle cells.
54.
Journée de la Recherche, Faculté de Médecine, Université Laval, Quebec, Mai 1999.
Cayrou, C., Ouellet, L. and Puymirat, J.: BTEB: a transcription factor involves in T3induces neurite outgrowth.
55.
Journée de la Recherche, Faculté de Médecine, Université Laval, Quebec, Mai 1999.
Dupré, N., Bouchard, J.-P. and Puymirat, J.: Hereditary neuropathies in Quebec.
56.
Club Thyroidien du Québec, Montreal, Mai 1999.
Cayrou, C. and Puymirat, J.: BTEB: a transcription factor involves in T3-induces neurite
outgrowth.
CV page 18 de 30
Puymirat, J.
57.
XXVIIIrd Colloque de la Société de Neuroendocrinologie, Marseille, Mai 1999.
Puymirat, J., Baas, D., Ouellet, L., Cayrou, C. and Sarliève, L.: Thyroid hormones and
brain development.
58.
Second International Myotonic Dystrophy Consortium (IDMC) Conference, North
Carolina, Avril 1999.
Furling, D., Marette, A. and Puymirat, J.: Insulin-like growth factor-I overcomes insulin
defective action in human myotonic dystrophy skeletal muscle cells.
59.
Second International Myotonic Dystrophy Consortium (IDMC) Conference, North
Carolina, Avril 1999.
Furling, D., Skuk, D., Bouchard, J.-P., Vilquin, J.-T., Tremblay, J.P. and Puymirat, J.:
Transplantation of myotonic dystrophy human myoblasts in SCID mice: a new potential
muscular model.
60.
Second International Myotonic Dystrophy Consortium (IDMC) Conference, North
Carolina, Avril 1999.
Furling, D. and Puymirat, J.: Myotonic dystrophy protein kinase (DMPK) expression in
primary skeletal muscle cell cultures derived from normal and DM patients.
61.
122rd Annual Meeting of the American Neurological Ass, Montreal, Octobre 1998.
Dupré, N., Bouchard, J.-P., Brunet, D., Vanasse, M., Lemieux, B. and Puymirat, J.:
Clinical and electrophysiologic study in french-canadian families with Charcot-MarieTooth disease type 1A associated with 17p11.2 duplication.
62.
122rd Annual Meeting of the American Neurological Ass, Montreal, Octobre 1998.
Furling, D., Bouchard, J.-P. and Puymirat, J.: Decrease levels in myotonin protein kinase
is associated with a delay in human myotonic dystrophy myoblast differentiation.
63.
40e Réunion Annue. du Club de Rech. Cliniques du Québec, Montreal, Octobre 1998.
Dupré, N., Bouchard, J-P., Brunet, D., Vanasse, M., Lemieux, B. and Puymirat, J.:
Genetics aspects of hereditary neuropathies in French-Canadian population.
64.
40e Réunion Annue. du Club de Rech. Cliniques du Québec, Montreal, Octobre 1998.
Furling, D., Lemieux, D., Bouchard, J.-P. and Puymirat, J.: Effects de l’IGF-1 (Insulinlike Growth Factor-1) on myotonic dystrophy human myoblast differentiation.
65.
40e Réunion Annuelle du Club de Rech. Cliniques du Québec, Montreal, Octobre 1998.
Bouchard, J.-P. and Puymirat, J.: Development of a data base for neuromuscular diseases
in Quiebec.
66.
Third International Conf. on Charcot-Marie-Tooth Disorders, Montreal, Octobre 1998.
Dupré, N., Bouchard, J.-P. and Puymirat, J.: A new mutation in the connexin gene on
chromosome X in the three french-canadian families with X-linked hereditary
neuropathy: phenotypic study.
CV page 19 de 30
Puymirat, J.
67.
48th Annual Meeting of the American Society of Human Genetics (ASHG), Denver,
Colorado, Octobre 1998.
Furling, D., Bérubé, D., Bouchard, J.-P. and Puymirat, J.: Beneficial effect of insulin-like
growth factor-I (IGF-I) on myotonic dystrophy skeletal muscle cells.
68.
9 e Journée Hospitalo-Universitaire, Manoir St-Castin, Quebec, Juin 1998.
Dupré, N., Bouchard, J.-P., Brunet, D., Vanasse, M., Lemieux, B. and Puymirat, J.:
Clinical and Genetics aspects of hereditary neuropathies in Quebec.
69.
33rd Meeting of the Canadian Congress of Neurogical Sciences, Montreal, Juin 1998.
Dupré, N., Puymirat, J., Bouchard, J.-P., Brunet, D., Vanasse, M. and Lemieux, B.:
Genetic aspects of Charcot-Marie-Tooth neuropathies in the French-Canadian
Population.
70.
XXVe Forum des Jeunes Chercheurs, Quebec, Mai 1998.
Furling, D., Lemieux, D., Bouchard, J.-P. and Puymirat, J.: Decrease levels in myotonin
protein kinase is associated with a delay in myotonic dystrophy myoblast differentiation.
71.
ACFAS, Quebec, Mai 1998.
Dupré, N., Bouchard, J.-P., Brunet, D., Vanasse, Michel, Lemieux, B. and Puymirat, J.:
Genetics of hereditary neuropathiesin the french-canadian population.
72.
Journées Génétiques au Québec, Montreal, Mai 1998.
Dupré, N., Bouchard, J-P., Brunet, D., Vanasse, M., Lemieux, B. and Puymirat, J.:
Hereditary neuropathies in Quebec.
73.
Journées Génétiques au Québec, Montreal, Mai 1998.
Bouchard, J.-P. and Puymirat, J.: Development of a data base for neuromuscular diseases.
74.
Annual Meeting of the Society for Neuroscience, Nouvelle-Orléans, Novembre 1997.
Denver, R.J. and Puymirat, J.: The basic transcription element binding protein (BTEB) is
a developmentally-regulated thyroid hormone-responsive gene in the central nervous
system of xenopus and rat.
75.
6e Congrès Conjoint Annuel des Sciences Neurologiques du Québec, Château
Montebello, Quebec, Octobre 1997.
Puymirat, J.: Classification of neuromuscular diseases.
76.
XXVIe Colloque de la Société de Neuroendocrinologie Expérimentale, Marseille,
Septembere 1997.
Puymirat, J. and Denver, R.: Identification of new thyroid hormone-regulated genes
expressed in the developing rat brain by cross-species hybridizations.
77.
ISN Satellite and UCON-Kroc Symposium,
Frontiers of myelin biology and
demyelinating disease, Mystic, Connecticut, Juillet 1997.
Baas, D., Bourbeau, D., Ittel, M.E., Dussault, J.H., Puymirat, J. and Sarliève, L.L.:
Oligodendrocyte maturation and progenitor cell proliferation are independently regulated
by thyroid hormone.
CV page 20 de 30
Puymirat, J.
78.
First Conference Internationale du Consortium sur la dystrophie myotonique de Steinert,
Paris, Juillet 1997.
Puymirat, J.: A data base for myotonic dystrophy.
79.
First Conference Internationale du Consortium sur la Dystrophie Myotonique de Steinert,
Paris, Juillet 1997.
Puymirat, J.: Charactérisation of a 54-kDA protein kinase recognized by an antimyotonin kinase antibody.
80.
First Conference Internationale du Consortium sur la Dystrophie Myotonique de Steinert,
Paris, Juillet 1997.
Puymirat, J., Vilquin, J.-T. and Tremblay, J.: Transplantation de DM myoblasts as a
model for myotonic dystrophy.
81.
79th Annual Meeting of the Endocrine Society, Minneapolis, Juin 1997.
R.J. Denver and Puymirat, J.: The basic transcription element binding protein (BTEB) is
a developmentally-regulated thyroid hormone-responsive gene in the central nervous
system of xenopus and rat.
82.
40th Congrès Annuel de la Fédération Canadienne des Sociétés de Biologie (FCSB),
Hilton -Quebec, Juin 1997.
Deschênes, I., Tremblay, J., Puymirat, J. and Chahine, M.: Immunocytochemical and
electrophysiological characterization of conditionally immortal human skeletal muscle
cells.
83.
40th Congrès Annuel de la Fédération Canadienne des Sociétés de Biologie (FCSB),
Hilton- Quebec, Juin 1997.
Furling, D., Bouchard, J.-P. and Puymirat, J.: Characterization of a 54-kDa human
protein kinase recognized by an antiserum raised against the myotonin kinase.
84.
69th Annual Meeting of American Thyroid Association, San Diego, Novembre 1996.
Puymirat, J. and Dussault, J.H.: Oligodendrocyte maturation and progenitor cell
proliferation are independently regulated by thyroid hormones.
85.
Annual Meeting of the Society for Neuroscience, Washington, Novembre 1996.
Deschênes, I., Puymirat, J. and Chahine, M.: Immunocytochemical and electrophysiological characterization of conditionnally immortal human skeletal muscle cells.
86.
6th Conference on : «Les maladies neuromusculaires», Versailles, France, Octobre 1996.
Puymirat, J. and Etongué-Mayer, P.E.: Charactérisation of a 54-kDa protein kinase
recognized by an anti-myotonin kinase antibody.
87.
6th Conference on : «Les maladies neuromusculaires», Versailles, France, Octobre 1996.
Puymirat, J., Deschênes, I., Chahine, M., Tremblay, J. and Paulin, D.: Increase
proliferative capacity of human myoblasts overexpressing the antigen T.
88.
XXXVIIIrd Annual Meeting of Club de recherche clinique du Quebec, Mont-Ste-Anne,
Quebec, Octobre 1996.
Puymirat, J.: Thyroid hormones and myelination.
CV page 21 de 30
Puymirat, J.
89.
Les Journées de la Génétique Humaine, Montreal, Juin 1996.
Puymirat, J., Faure, R., Chahine, M., Tremblay, J. and Bouchard, J.P.: Study of the
pathogenesis of myotonic dystrophy.
90.
25th Annual Meeting of the Soc for Neuroscience,San Diego, California, Novembre 1995
Trépanier G., Furling D. and Puymirat, J.: "Immunocytochemical localization of Seglutathione peroxidase in the adult mouse brain".
91.
45th Annual Meeting of the American Society of Human Genetics, Octobre 1995.
Puymirat, J., Etongue-Mayer, P., Chahine, M., Tremblay, J. and Bouchard, J.P.
Immortalization of human muscle cells: a model system for the derivation of dystrophic
human muscle cells.
92.
45th Annual Meeting of the Ame Society of Human Genetics, Mineapolis, Octobre 1995.
Puymirat, J., Etongué-Mayer, P.E., Baas, D. and Bouchard, J.P.: "Differential expression
of myotonic dystrophy mRNA in rat brain cells".
93.
37th Annual Meeting of Club de Rech Clinique du Québec, Bromont, Septembre 1995.
Furling, D., Puymirat, J. and Mirault, M.-E. Overexpression of glutathion peroxydase
and resistance to dopaminergic neurotoxins.
94.
11th International Thyroid Congress, Toronto, Septembre 1995.
Puymirat, J. and Dussault, J.H.: Differential regulation of gene expression in the same
cell by the interaction of thyroid hormones with the thyroid receptor 1 (TR1).
95.
American Society of Human Genetics, Montreal, Canada, 1994.
Puymirat, J., Etongué-Mayer, P., Faure, R., Bouchard, J.-P., Laframboise, R. and
Thibault, M.-C.: The myotonic dystrophy gene product is a tyrosine/serine kinase:
Decreased levels of M-PK activity are associated with the congenital and adult forms of
myotonic dystrophy.
96.
Canadian Congress of Neurological Sciences, Terre-Neuve, Canada, 1994.
Bouchard, J.-P., Etongué-Mayer, P., Faure, R., Thibault, M.C. and Puymirat, J.:
Decreased levels of myotonic dystrophy activity in congenital and adult forms of
myotonic dystrophy.
97.
76th Annual Meeting of the Endocrine Society, Anaheim, CA, USA, 1994.
Dussault, J.H. et Puymirat, J.: Thyroid hormone regulates c-jun gene expression in
neuro-2a cells which overexpress the 1 thyroid receptor.
98.
XXIst Meeting des jeunes chercheurs, Reims, France, 1994.
Baas, D., Ittel., M.E., Hauw, J.J., Puymirat, J. and Sarlieve, L.L.: Expression of thyroid
hormone receptor mRNA in Schwann cells.
99.
Annual Meeting of the American Thyroid Association, Chicago, USA, 1994.
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Puymirat, J.
Puymirat, J. and Dussault, J.H.: Protein kinase inhibitor (H7) blocks the effect of
triiodothyronine on acetylcholinesterase activity and its mRNAs, in neuroblastoma cells
that overexpress the thyroid receptor 1.
100.
XXIIIrd Colloque de la Société de neuroendocrinologie expérimentale, Sophia Antipolis,
France, 1994.
Puymirat, J., Cossette, L. and Dussault, J.H.: Regulation of brain acetylcholinesterase
by thyroid hormone : Evidence for the involvement of a protein kinase.
101.
XXIInd Annual Meeting of the European Thyroid Association, Vienna, Austria, 1994.
Dussault, J.H. and Puymirat, J.: Thyroid hormone regulates immediate-early gene
expression in neuro-2a cells which overexpress the 1 thyroid receptor.
102.
63rd Annual Meeting of the Royal College of Physicians and Surgeons of Canada,
Toronto, Canada, 1994.
Bourbeau, D., Baas, D., Carré J.L., Louis, J.C., Sarliève, L.L., Dussault, J.H. and
Puymirat, J.: Expression différentielle des récepteurs de l'hormone thyroïdienne 1 et 1
durant la différenciation oligodendrocytaire.
103.
17th Annual Meeting of the Canadian College of Neuropsychopharmacology, Québec,
Canada, 1994.
Furling, D., Puymirat, J. and Mirault, M.E.: The overexpression of glutathione
peroxydase by human catecholaminergic neuroblastoma cells increased their resistance
to 6-OHDA toxicity.
104.
37th Annual Meeting of the Canadian Federation of Biological Societies, Montréal, 1994.
Furling, D., Puymirat, J. and Mirault, M.E.: Characterization of human
catecholaminergic neuroblastoma cell transfectants overexpressing glutathione
peroxydase.
105.
Annual Meeting of the Society for Neuroscience, Miami Beach, Florida, U.S.A, 1994.
Furling, D., Barden, N., Puymirat, J. and Mirault, M.E.: Positive effects of glutathione
peroxidase overexpression on the responses of human catecholaminergic neuroblastoma
cells to free radicals generating agents.
106.
44th Annual Meeting of the Amer. Society of Human Genetics, Montréal, 1994.
Puymirat, J., Etongué-Mayer, P., Faure, R., Bouchard, J.-P., Laframboise, R. and
Thibault, M.C.: The myotonic dystrophy gene product is a tyrosine/serine kinase:
Decreased levels of M-PK activity are associated with the congenital and adult forms of
myotonic dystrophy.
107.
Collomed Symposium. Molecular and Cell Biology of Myelin diseases. Lausanne,
Switzerland, 1994.
Baas, D., Ittel, M.E., Hauw, J.J., Puymirat, J. and Sarliève., L.L.: Expression of thyroid
hormone receptor mRNA in Schwann cell line.
108.
Club des Cellules Gliales, Paris, France, 1994.
CV page 23 de 30
Puymirat, J.
Baas, D., Ittel, M.E., Bourbeau, D., Hauw, J.J., Expression of thyroid hormone receptor
mRNA in Schwann cells.
109.
37th Meeting of the Canadian Federation of Biological Societies, Mont, Quebec, 1994.
Trépanier, G., Tremblay, A., Puymirat, J. and Mirault, M.E. Immunocytochemical
localization of glutathione peroxidase in brain of transgenic GPx mice.
110.
Fourth Joint LWPES/ESPE Meeting, San Francisco, USA, 1993.
Roy, J., Puymirat, J., Van Vliet, G., Doyon, J. and Dussault, J.H.: Neurological,
neuroradiological and neuropsychological evaluation of patients with congenital
hypothyroidism (CH) at 15-years.
111.
Thyroid and the brain.
New England Regional Newborn Screening Program, Boston, 1993.
112.
International Council for Control of Iodine Difficiency Disorders Symposium,
Philadelphia, USA, 1993.
Dussault, J.H., Glorieux, J., Puymirat, J., Van Vliet, G., Roy, J. and Doyon, J.:
Intellectual and neurological development at age 12 and 15 years of children with
congenital hypothyroidism (CH) detected by neonatal screening.
113.
75th Annual Meeting of the Endocrine Society, Las Vegas, USA, 1993.
Lebel, J.M., Cossette, L., Beaudoin, N., Garceau, L., Dussault, J.H. and Puymirat, J.:
Overexpression of the thyroid receptors b1 and a1 in neuronal (neuro-2a) and glial (C6)
cell lines: the effect of L-Triiodothyronine (L-T3) on nerve cells proliferation is
mediated by the 1 receptors and specific to neurones.
114.
Club de recherches cliniques du Québec, Pointe-au-Pic, Canada, 1993.
Etongué-Mayer, P., Faure, R., Thibault, M.-C., Bouchard, J.-P. and Puymirat, J.:
Caractérisation d’un anticorps dirigé contre la myotonine protéine kinase (MK):
Démonstration de l’activité kinase.
115.
Society for Neuroscience, Washington, USA, 1993.
Mirault, M.-E., Tremblay, A., Trépanier, G., Furling, D., Di Paolo, T. and Puymirat, J.:
Overexpression of glutathion peroxidase in the brain of transgenic mice increases their
resistance to MPTP-mediated neurotoxicity.
116.
Keystone Symposia on Molecular & Cellular Biology, Lake Tahoe, CA, USA, 1993.
Mirault, M.-E., Tremblay, A., Trépanier, G., Furling, D., Di Paolo, T. and Puymirat, J.:
Transgenic mice overexpressing SE-glutathione peroxidase in the brain: differential
resistance to MPTP-mediated neurotoxicity.
117.
Genetic Society of Canada Meeting, Lac Delage, Quebec, 1993.
Etongué-Mayer, P., Faure, R., Thibault, M.-C. and Puymirat, J.: The myotonin protein
kinase: Characterization of the catalytic activity in vivo.
118.
American Society of Human Genetics, 1993.
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Puymirat, J.
Sabourin, L.A., Tsilfidis, C.T., Etongué-Mayer, P., Puymirat, J., Karpati, G. and
Korneluk, R.G.: Investigation of the role of the myotonic dystrohpy kinase (DMK) in the
differentiation of cultured myoblasts.
119.
67th Annual Meeting of the American Thyroid Association, Tampa, USA, 1993.
Puymirat, J., Lebel, J.M. and Dussault, J.H.: Overexpression of the thyroid receptor 1
induces differentiation in neuro-2a cells.
120.
67th Annual Meeting of the American Thyroid Association, Tampa, USA, 1993.
Baas, D., Sarliève, L.L. and Puymirat, J.: Temporal expression of the 1 and 1 thyroid
receptor during oligodendrocyte differentiation.
121.
Congrès Annuel de la Société d'Endocrinologie, San Antonio, Texas, USA, 1992.
Lebel, J.M., Dussault, J.H. and Puymirat, J.: Preferential localization of the 1 and 1
thyroid receptor mRNAs in proliferative and non proliferative astrocytes respectively.
122.
Conference of «La Société des neurosciences françaises», Strasbourg, France, 1992.
Sarliève, L., Beaudoin, N., Dalençon, D., Furling, D., Dussault, J.H. and Puymirat J.:
Expresion of thyroid hormone receptors in oligodendrocyte in culture.
123.
9e Congrès International d'Endocrinologie, Nice, France, 1992.
Lebel, J.M., Dussault, J.H. and Puymirat, J.: In vivo localization of the
receptor mRNAs in proliferative and non proliferative astrocytes.
1
and
1
thyroid
124.
66e Congrès Annuel de l'Association Américaine de la Thyroïde, Rochester, Minnesota,
USA, 1992.
Maillette, A., Sarliève, L., Lebel, J.M., Dussault, J.H. and Puymirat, J.: Influence of
triiodothyronine on the differentiation of oligodendrocytes.
125.
XXXIVe Congrès Annuel du Club de recherches cliniques du Québec, Montébello,
Canada, 1992.
Lebel, J.M., Sarliève, L.L., Dussault, J.H. and Puymirat, J.: Expression of thyroid
hormone receptor mRNA in astrocytes and oligodendrocytes: Effect of T3.
126.
83e Congrès Annuel de l'Association Américaine pour la recherche sur le Cancer, San
Diego, U.S.A, 1992.
Mirault, M.E., Trembaly, A., Pothier, F., Piguet, P.F., Surette, M., Julien, P. Moorjani,
S., Puymirat, J. and Borgeat, P.: Phenotypes of transgenic mice overexpressing
glutathione perixodase.
127.
Intellectual and neurological development at age 15 years of children with congenital
hypothyroidism. Québec, 1992.
128.
15th Annual Meeting of the European Neuroscience Association, Munich, 1992.
Sarliève, L.L, Beaudoin, N., Dussault, J.H. and Puymirat, J.: Expression of L-3,5,3'triiodothyronine of nuclear receptor mRNAs in pure oligodendrocyte secondary cultures.
CV page 25 de 30
Puymirat, J.
129.
XXIst Colloque de la Société de neuroendocrinologie expérimentale, Nancy, France,
1992.
Graff, M.N., Baas, D., Puymirat, J., Sarliève, L.L. and Delaunoy, J.P.: Expresion of
thyroid hormone receptors and modulation of glutamine synthétase activity in primary
ependymal cell culture.
130.
10e Congrès Internationale de Thyroïde, La Haye, Pays-Bas, 1991.
Dussault, J .H., L’Héreault, S. and Puymirat, J.: Expression of  and  thyroid hormone
receptor mRNAs in cultured rat cerebral hemisphere neurons.
131.
10th Congrès Internationale de Thyroïde, La Haye, Pays-Bas, 1991.
Puymirat, J., Dussault, J.H., Schmidt, E.D.L. and Dussault, L.: Immunocytochemical
localization of the and forms of thyroid receptors in brain cell cultures.
132.
Symposium Keystone, Tamarron, U.S.A, 1991.
Puymirat, J., L’Héreault, S., Turgeon, C. and Dussault, J.H.: Differential expression and
regulation of  and  thyroid hormone receptor mRNAs in brain cell cultures.
133.
73e Congrès Annuel de la Société d'Endocrinologie, Washington, U.S.A, 1991.
Puymirat, J., Turgeon, C., L’Hérault, S. and Dussault, J.H.: Expression of  and 
thyroid hormone mRNAs in the developing rat cerebral hemispheres: in vivo and in vitro
study.
134.
20e Congrès de la Société de Neuroendocrinologie, Geneva, Switzerland, 1991.
Puymirat, J., L’Héreault, S., Turgeon, C. and Dussault, J.H.: Expression of thyroid
hormone receptors mRNAs in the developing brain: in vivo et in vitro study
135.
65e Congrès Annuel de l'Association Américaine de la Thyroïde, Boston , U.S.A, 1991.
Puymirat, J. and Dussault, J.H.: Influence of triiodothyronine (L-T3) on the expression
of TR mRNAs in astrocyte cultures.
136.
New England Regional Newborn Screening Program, Neurological Follow-up.
Portland, 1991.
137.
8e Congrès International de Génétique humaine, Washington, U.S.A, 1991.
Labelle, Y., Phaneuf, D., Puymirat, J. and Tanguay, R.M.: Expression analysis of
fumarylacetoacetate hydrolase, the enzyme dificient in hereditary tyrosimemia.
138.
2e Congrès International de Neuroendocrinologie, Bordeaux, France, 1990.
Puymirat, J., Marchand, R., Sarliève, L. et Dussault, J.H.: Mapping of thyroid receptors
in the adult rat brain.
139.
XXXIIe Réunion annuelle du Club de recherches cliniques du Québec, La Malbaie,
Canada, 1990.
Puymirat, J., L’Héreault, S. and Dussault, J.H.: Expression of thyroid hormones mRNA
in primary neuronal cultures.
140.
XXXIIe Réunion annuelle du Club de recherches cliniques du Québec, La Malbaie,
Canada, 1990.
CV page 26 de 30
Puymirat, J.
Turgeon, C., Puymirat, J. and Dussault, J.H.: Expression of thyroid hormone receptors in
the developing cerebellum and cerebral hemispheres.
141.
Conférence Neurosciences , Montpellier, France, 1989.
Peyrin, L., Fallet-Bianco, C., Puymirat, J., Jeannin, Ch., Valade, D., Mas, J.L. and
Rondot, P.: levels of noradrenergic activity in dementia of the Alzheimer type.
142.
Conférence Neurosciences, Montpellier, France, 1989.
Fallet-Bianco, C., Jeannin, Ch., Valade, D., Peyrin, L., Mas, J.L., Rondot, P. and
Puymirat, J.: Value of the levels of acetylcholinesterase activity in the cerebrospinal
fluid in dementia: a 5 years longitudinal study.
143.
Conférence IPSEN, Toulouse, France, 1989.
Fallet-Bianco, C., Jeannin, Ch., Valade, D., Peyrin, L., Mas. J.L., Rondot, P. and
Puymirat, J.: Is acetylcholinesterase activity of cerebrospinal fluid, a useful diagnostic
marker of dementia of Alzheimer type? A longitudinal study over a five-year span.
144.
Conférence IPSEN, Toulouse, France, 1989.
Peyrin, L., Fallet-Bianco, C., Puymirat, J., Jeannin, Ch., Valade, D., Mas, J.L., Fredy, D.
and Rondot, P.: Norepinephrine and 3-methoxy - hydroxyphenylglycol assays in
cerebrospinal fluid show alterations of brain noradrenergic neurons in demented patients.
145.
12e Congrès de la Société Internationale de Neurochimie, Algrave, Portugal, 1989.
Besnard, F., Luo, M., Janet, T., Labourdette, J., Puymirat, J. and Dussault, J.H.: Pure
cultured rat oligodendrocytes express high level of an erbA protooncogene transcript.
146.
3e Colloque national des neurosciences, Montpellier, France, 1989.
Sarliève, L.L., Besnard, F., Janet, T., Luo, M., Puymirat, J. and Dussault, J.H.:
Expression of thyroid recptors in oligodendrocyte cultures.
147.
Society d'Endocrinologie, Seattle, USA, 1989.
Garza, R., Puymirat, J. and Dussault, J.H.: Immunocytochemical localisation of thyroid
hormone nuclear receptors in cultured cholinergic neurons using a monoclonal antibody
against rat liver thyroid hormone receptor.
148.
Association Américaine de Thyroïde, San Francisco, USA, 1989.
Garza, R., Puymirat, J. and Dussault, J.H.: The presence of thyroid hormone receptors in
cultured cholinergic neurons is correlated with a triiodothyronine morphological effect.
149.
Club de recherches cliniques du Québec, Sainte-Adele, Canada, 1989.
Garza, R., Puymirat, J. and Dussault, J.H.: The presence of thyroid hormone receptors in
cultured cholinergic neurons is correlated with a triiodothyronine morphological effect.
150.
"Iodine and the Brain", Institut National de Santé, Béthesda, U.S.A., 1988.
Puymirat, J., Garza, R. and Dussault, J.H.: Influence of triiodothyronine on the
development of fetal brain cholinergic neurons cultured in a chemically defined medium.
151.
XIXe Congrès de la Société Américaine de Neurochimie, N-Orléans, U.S.A., 1988.
CV page 27 de 30
Puymirat, J.
Puymirat, J., Luo, M. and Dussault J.H.: Immunocytochemical localization of LTriiodothyronine nuclear receptor in astroglial cell cultures.
152.
XIXe Congrès de la Société Américaine de Neurochimie, N-Orléans, U.S.A., 1988.
Besnard, F., Luo, M., Puymirat, J., Labourdette, G. and Sarliève,
Immunocytochemical localization of T3 receptors in rat oligodendrocytes.
L.:
153.
VIIIe Séminaire hivernal des neurosciences européennes, Tignes, France, 1988.
Besnard, F., Luo, M., Puymirat, J., Labourdette, G. and Sarliève, L.:
Immunocytochemical localization of T3 nuclear receptors in pure rat oligodendrocytes
producing myelin-related membranes.
154.
XXIVe Symposium des Modèles Biologique. Prague, Tchécoslovaquie, 1988.
Sarliève, L., Besnard, F., Yusta, B., Aranda, A., Luo, M., Dussault, J.H. and Puymirat,
J.: Hormonal factors in regulation of nervous tissue differentiation in tissue culture with
emphasis upon nuclear triiodothyronine receptors.
155.
Congrès Annuel de l'Association Américaine de Thyroïde, Montréal, Canada, 1988.
Garza, R., Dussault, J.H. and Puymirat, J.: Évidence of a direct effect of triiodothyronine
on the development of fetal brain cholinergic neurons cultured in a chemically defined
medium.
156.
XXIIIe Congrès Canadien des Sciences Neurologiques, 1988.
Puymirat, J., Gueguen, B. and Rondot, P.: clinical and electrophysiological effects of
TRH administry in amyotrophic lateral scelrosis.
157.
XXIIIe Congrès Canadien des Sciences neurologiques, 1988.
Puymirat, J., Gomez, S., Bianco, C. and Rondot, P.: Levels of acetylcholinesterase and
somatostatin in the cerebrospinal fluid in dementia of the Alzheimer type.
158.
Club de recherches cliniques, Charlevoix, Canada, 1988.
Garza, R. Dussault, J.H. and Puymirat, J.: Direct effect of thyroid hormones on the
development of brain cholinergic neurons in vitro.
159.
Congrès annuel de l'Association Américaine de la Thyroïde, Washington, USA, 1987.
Puymirat, J., Garza, R. and Dussault, J.H.: Influence of triiodothyronine on the
development of fetal brain cholinergic neurons cultured in chemically defined medium.
160.
XVIIe Congrès de «Soc. de neuroendocrinologie expérimentale», Lyon, France, 1987.
Puymirat, J., Luo, M. and Dussault, J.H.: Immunocytochemical localisation of thyroid
hormone receptors in primary astrocyte cultures.
161.
Congrès de «Union médicale du Canada», Montébello, Canada, 1987.
Garza, R., Dussault, J.H. and Puymirat, J.: Influence of triiodothyronine (T3) on the
maturation of brain cholinergic neurons in cultures.
162.
Club français de neuropathologie, Paris, France, 1987.
Sarliève, L.L., Besnard, F., Luo, M. and Puymirat J.: Immunocytochemical localisation
of thyroid hormone receptors in primary oligodendrocyte cultures.
CV page 28 de 30
Puymirat, J.
163
XVIe Conférence Soc. de neuroendocrinologie expérimentale», Marseille, France, 1986.
Puymirat, J., Barret, A., Faivre-Bauman, A. and Tixier-Vidal, A.: Hormonal control of
neuronal differentiation.
164.
Conférence sur : «Les investigations de la maladie d'Alzheimer: Génétique et
Epidémiologie», Cascapedia, 1986.
Puymirat, J.: Rôle des facteurs de croissance dans la maladie d'Alzheimer.
165.
XVe Colloque de la Soc. neuroendocrinologie expérimentale Gif/Yvette, France, 1985.
Puymirat, J., Faivre-Bauman, A., Barret, A. and Tixier-Vidal, A.: Rôle de la
triiodothyronine sur la différentiation des neurones dopaminergiques de l'hypothalamus
de souris foetales cultivés en milieu défini.
166.
XXe OHOLO Conférence, Eilat, Israël, 1985.
Puymirat, J., Davous, P., Valade, D., Gomez, S. and Rondot, P.: Acetylcholinesterase
activity and somatostatin like immunoreactivity in the CSF of demented patients.
167.
7e Congrès International d'Endocrinologie, Quebec, Canada, 1984.
Puymirat, J., Loudes, C., Faivre-Bauman, A., Lassare ,C., Binoux, M. and Tixier-Vidal,
A.: Effect of triodothyronine on development in vitro of dopaminergic and thyroliberin
hypothalamic neurons.
168.
Neuroendocrinologie Feotale, Mariensee, RFA, 1984.
Puymirat, J., Barret, A. and Tixier-Vidal, A.: Effects of thyroid hormones on the
development of mouse hypothalamic dopaminergic neurons.
169.
XVe Congrès de psychoneuroendocrinologie, Vienne, Autriche, 1984.
Puymirat, J., Gomez, S., Davous, P., Valade, D. and Rondot, P.: Somatostatin like
immunoreactivity and acetylcholinesterase activity in the CSF of patients with Azheimer
disease.
170.
Ve Symposium sur les «Cathécholamines», Göteborg, Sweden, 1983.
Puymirat, J., Barret, A., Loudes, C., Faivre-Bauman, A. and Tixier-Vidal, A.:
Morphological effect of triiodothyronine on dopaminergic neurons from fetal mouse
hypothalamic and mesencephalic cells cultured in serum free medium.
171.
1ère Conférence Annuelle «Société française de biologie cellulaire», Paris, France, 1983.
Faivre-Bauman, A., Puymirat, J., Loudes, C., Barret, A. and Tixier-vidal, A.: Factors
involved in attachment and migration of hypothalamic neurons in vitro.
172.
30e Congrès of " Société Européenne de Culture de Tissu ", Paris, France, 1982.
Faivre-Bauman, A., Loudes, C., Puymirat, J., Tixier-Vidal, A. and Bourre, J.M.: Role of
hormones and fatty acids on the development of hypothalamic neurons in the absence of
serum.
173.
E.M.B.O. Atelier de travail “Les mécanismes moléculaires dans le développement du
système nerveux”, Strasbourg, France, 1982.
CV page 29 de 30
Puymirat, J.
Puymirat, J., Barret, A., Faivre-Bauman, A., Loudes, C. and Tixier-Vidal, A.: Effects of
triiodothyronine on the development of mouse fetal hypothalamic cells in vitro.
174.
3e Congrès " de la Société de Neurosciences Développementales ", Patras, Grèce, 1982.
Loudes, C., Faivre-Bauman, A., Grouselle, D., Puymirat, J. and Tixier-Vidal, A: In vitro
differentiation of hypothalamic neurons in serum-free medium.
175.
3e Congrès de la Société de Neurosciences Développementales, Patras, Greece 1982.
Puymirat, J., Loudes, C., Faivre-Bauman, A., Lassare, C., Binoux, M. and Tixier-Vidal,
A.: Effect of triodothyronine on development in vitro of dopaminergic and thyroliberin
hypothalamic neurons.
176.
29e Congrès de la "Société Euro de Culture de Tissu", Noorwijkerhout, Pays-Bas, 1981.
Faivre-Bauman, A., Puymirat, J., Rosembaum, E., Grouselle, D. and Tixier-Vidal, A.:
Expression of neuronal activities in serum-free medium culture of fetal mouse brain
cells.
177.
1er Congrès International de la Société de Neurosciences Développementales,
Strasbourg, France, 1980.
Puymirat, J., Faivre-Bauman, A. and Tixier-Vidal, A.: Pre-natal and post-natal
ontogenesis of neurotransmetter synthetising enzymes and tetanus toxin binding capacity
in the mouse hypothalamus.
178.
1st Congrès International de la Société de Neurosciences Développementales Strasbourg,
France, 1980.
Faivre-Bauman, A., Puymirat, J., Rosembaum, E. and Tixier-Vidal, A.: Evidence for
neuronal activities in primary cultures from fetal mouse brain cells grown in serum-free
medium. Modulation by different hormones.
179.
Conférence Nationale de Neurosciences: "Bilan et perspectives des Neurosciences",
Touquet, France, 1980.
Faivre-Bauman, A., Puymirat, J., Rosenbaum, E. and Tixier-Vidal, A.: Expression of
neuronal activities in primary neuronal cultures grown in serum-free medium.: Role of
thyroid hormones.
CV page 30 de 30