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Creating & Developing Companies To Improve the Human Condition Technology Development Stage Arcuro Medical Omeq Medical Vensica Medical All-suture meniscus repair device Comprehensive system with knotless fixation enables secure, reliable meniscus repair. Lee Ranon, CEO +972.52.651.1506 [email protected] Epidural injection system Sensor-based system gives accurate positioning information and prevents complications. Lior Margalit, CEO +972.54.431.5304 [email protected] www.omeqmedical.com Improved treatment of bladder disease Ultrasound-based device improves drug uptake in a quick, pain-free procedure. Avner Geva, CEO +972.54.495.9544 [email protected] Escala Medical OrthoSpin VisiDome Treatment for pelvic organ prolapse First minimally invasive, incisionfree, mesh-free repair device for pelvic organ prolapse. Chen Barak, CEO +972.54.444.8585 [email protected] Robotic external fixation system The system will eliminate the dependency on patient compliance, reduce complications, and improve outcomes. Ofer Vikinsky, CEO +972.54.617.7828 [email protected] Accommodative intraocular lens (IOL) Next-generation IOL provides clear, full range of vision and spectacle independence after cataract surgery. Nir Eliaz, CEO +972.52.551.3055 [email protected] Fidmi Medical S.T. Stent Innovative enteral feeding device Comprehensive gastrostomy system for initial endoscopic placement and multiple replacements eliminates tissue damage and accidental dislodgment. Shahar Millis, CEO +972.52.651.1132 [email protected] Removable nasal stent Short-term stent, implanted following sinus surgery. Joseph Flomenblit, Ph.D., CEO +972.54.738.7188 [email protected] www.ststent.com Breakthrough Medical Companies To Improve the Human Condition Trendlines Medical teams with passionate innovators, entrepreneurs, and investors to establish innovation-based companies focused on developing disruptive medical devices and technologies that improve patient outcomes and reduce skyrocketing health care costs. In 2014 and 2010, Trendlines Medical was named Best Incubator by Israel’s Office of the Chief Scientist of the Ministry of Economy. Trendlines’ staff of more than 30 provides business and technology development, marketing, finance, and administrative support — and access to its extensive global network of investors and strategic partners. Business Development Stage CoreBone LapSpace Medical NeuroQuest Coral-based bone graft material Bone substitute based on proprietary coral incubation and bioactive properties encourages development of new bone. Ohad Schwartz, CEO +972.52.260.5252 [email protected] Inflatable laparoscopic retractor Inflatable balloon retractor efficiently and gently retracts abdominal organs such as the intestines. Assaf Livne, CEO +972.54.302.2388 [email protected] www.lapspacemedical.com Biomarker for Alzheimer’s Diagnostic tools use results from a simple blood test for early detection of Alzheimer’s. Dan Touitou, CEO +972.54.749.7004 [email protected] www.neuro-quest.com Endobetix Leviticus Cardio ProArc Medical Minimally invasive implant for type 2 diabetes Bile diversion device improves glucose tolerance in the treatment of type 2 diabetes. Chen Porat, CEO +972.54.312.9939 [email protected] www.endobetix.com Wireless energy system Coplanar Energy Transfer (CET) system provides power wirelessly to left ventricular assist devices. Michael Zilbershlag, CEO +972.50.880.7135 [email protected] www.leviticus-cardio.com BPH implant Minimally invasive, outpatient treatment relieves symptoms of enlarged prostate (BPH). Shai Golan, CEO +972.54.222.0093 [email protected] www.proarcmedical.com Gordian Surgical Magdent Pro-IV Medical Trocar with built-in closure Easy-to-use trocar with built-in closure device provides secure, suture-anchored fascia closure. Zvi Peer, CEO +972.50.420.3333 [email protected] www.gordiansurgical.com Electromagnetic healing cap Specialized healing cap accelerates bone formation and quality for shorter dental implant procedures. Moshe Neuman, D.M.D., Founder +972.54.763.1501 [email protected] Transfusion and infusion safety Specialized controller and mobile app prevent errors when infusing, transfusing, and administering IV medications. Michal Devir, M.D., Co-Founder +972.54.477.3736 [email protected] www.pro-iv.co.il Headway Medical MediValve SiL Vascular Device for head and neck pain Computer-controlled, patented treatment table moves the head gently to relieve head and neck pain. Tamir Levital, CEO +972.54.234.7786 [email protected] www.headwaymedical.com TAVI positioning system Nitinol-based device allows accurate valve positioning during TAVI (Transcatheter Aortic Valve Implantation) procedures. Assaf Klein, CEO +972.54.229.9572 [email protected] www.medivalve.com Drug-coated balloon Unique surface and activation mechanism improves drug delivery and clinical outcomes. Omer Schalit-Cohen, Acting CEO +972.52.600.6588 [email protected] www.sil-vascular.com IonMed Nephera Stimatix GI Cold-plasma wound closure system The Bioweld1 "biowelding" system presents a new paradigm in surgical wound closure and healing. Shai Levanon, CEO +972.54.454.1900 [email protected] www.ion-med.com Stimulation catheter for improved renal function Modulating sympathetic nerve activity in the urinary tract of patients with acute heart failure. Robert Bash, CEO +972.54.800.5550 [email protected] Low-profile ostomy devices Voluntary bowel evacuation to help stoma patients resume normal activities and improve quality of life. David Hanuka, CEO +972.52.620.1940 [email protected] www.stimatix-gi.com Revenue Stage ApiFix Scoliosis treatment device Less invasive, ratchet-based device gradually and gently shifts the spine into the correct position. Uri Arnin, CEO +972.54.550.1406 [email protected] www.apifix.com Breezy Triple-action oral hygiene products Proprietary microcapsules disperse safe, natural compounds to remove odor-producing bacteria in the mouth. Hillel Lerman, CEO +972.54.421.5816 [email protected] www.breezylike.com Dune Medical Devices Optimized tumor excision Real-time, intraoperative optimization of excisions in surgical oncology procedures. Gil Rosen, Chief Commercial Officer +972.4.617.8002 [email protected] www.dunemedical.com ETView Airway management and visualization Single- and double-lumen ventilation tubes integrate continuous, high-resolution airway imaging system. William Edelman, CEO +1.781.436.0509 [email protected] www.etview.com Successes AwardWinners Acquisitions Public Company 2014, 2010 Mitral valve implant Best Incubator* Best Start-Up 2014* Scoliosis treatment device Low-profile ostomy devices Best Start-Up 2013* Best Start-Up 2012* Automated urine monitoring Dry powder inhaler Acquired by Baxter Acquired by OPKO Health Microlaparoscopy technology Hernia mesh deployment Acquired by Teleflex Acquired by Covidien Airway management and visualization * Israel's Office of the Chief Scientist Trendlines Medical Management Eran Feldhay, M.D. CEO More than 15 years of management experience in medical devices and health care IT at Medcon and McKesson Veteran entrepreneur with more than 35 years of business development, investment, and management experience [email protected] [email protected] Omer Schalit-Cohen VP, Business Development Edit Goldberg, D.M.D. VP, New Ventures Extensive experience in business development, marketing, and product management at McKesson Held management and strategic development positions at Omrix, J&J, and Life Bond [email protected] [email protected] 02/2015 Full bios at www.trendlines.com/about/management The Trendlines Group Ltd. The Trendlines Building Misgav Business Park M.P. Misgav 2017400 Israel Office +972.72.260.7000 [email protected] www.trendlines.com Todd Dollinger Chairman and CEO, Trendlines Chairman, Trendlines Medical