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Human Body Systems I It’s all about Homeostasis!!! Our body systems have evolved to maintain constant internal conditions including- Temperature Water Level Oxygen Level pH Glucose Level *A.T.P. Level Integumentary System Parts: Skin – Epidermis, Hair with Muscle, Sweat Glands, Nerves, Fat, Blood Vessels Hair, Nails Functions: 1. Sense of TouchHeat, Cold, Pain, Pressure 2. Maintaining Homeostasis including temperature regulation, water balance 3. Protection from injury and UV solar radiation (melanin protein) Malignant Melanoma - The most dangerous form of Skin Cancer - Spreads (Metastasizes) very easily to other, more important systems like lungs, liver, brain, etc. - Often caused by overexposure to ultraviolet (UV) radiation from the sun or tanning - Like all cancers, caused by mutation to the genes that control cell division / Mitosis (Oncogenes) - cells divide out of control forming masses called Tumors that get in the way of normal function. Respiratory System Parts: Diaphragm, Nose, Mouth, Pharynx, Trachea, Cilia, Bronchi, Bronchioles, Lungs, Alveoli, Red Blood Cells, Blood Plasma, Larynx Functions: 1. Diffusion of Oxygen from air to red blood cells 2.Diffusion of Carbon Dioxide from blood to air 3. Capture of airborne bacteria in mucus and motivation of pathogens up and out using Cilia Notes: Remember that we inhale when the Diaphragm flexes and exhale when it relaxes. Diffusion is a passive process where substances move from an area of high concentration to an area of low concentration. Lung Cancer - Extremely deadly form of cancer - Often caused by the most dangerous voluntary human behavior – smoking tobacco! - Cells are killed by hot poisonous smoke and then need to be replaced by Mitosis - Like all cancers, caused by mutation to the genes that control cell division / Mitosis (Oncogenes) - Cells divide out of control forming masses called Tumors that get in the way of normal function. Circulatory System Parts: Blood, Heart, Arteries (away from the heart), Capillaries, Veins (back to the heart) Functions: 1. Delivery of Oxygen from Lungs and Food from Liver to tissues 2. Removal of Carbon Dioxide to the lungs and other Waste Products to the Kidneys (liquids) and Large Intestine (solids) Notes: The right side of the Heart pumps low oxygen blood to the lungs and back to the left side (Pulmonary Circulation). The left side pumps high oxygen blood out to the tissues and back to the right side (Systemic Circulation). Heart Attack - Often caused by poor diet with lots of Saturated Fats and / or lack of exercise. - Saturated Fats (plaque) build up and block the arteries that bring oxygen to the heart muscle (Coronary Arteries). - Lack of oxygen causes the heart muscle to die which really hurts a lot! - If enough of the heart muscle dies, the heart cannot function and the person dies with it. Endocrine System Parts: Hypothalamus and Glands, Hormones (chemical messages) Function: 1. Carry chemical messages through the blood stream to activate or inactivate organs. 2. Cause developmental changes in the body – puberty! Most Important parts to know in the Endocrine System 1. Hypothalamus – part of the brain that relays information and instructions to the Pituitary Gland 2. Pituitary Gland – the “Master Gland”, using directions from the Hypothalamus produces various Stimulating Hormones to control the other glands. The Tiger QuestionSensing of Large Predator-> 1. Brain informs Hypothalamus (the relay station)-> 2. Pituitary (the Master Gland) Activated,, releases Adrenal Stimulating Hormone (ASH) -> 3. Adrenals Activated, release Adrenalin (Epinephrine) -> 4. “Fight or Flight (or Freeze)” Response Increased Heart Rate, Respiration Rate, Glucose Processing – Energy!!! The Sandwich QuestionSensing sandwich-> 1. Brain informs Hypothalamus (the relay station)-> 2. Pituitary (the Master Gland) Activated, releases Thyroid Stimulating Hormone (TSH) -> 3. Thyroid Activated, releases Thyroxin hormone4. Cascade of Digestive Organs Activated Diabetes Two kinds1. Type I - Inherited genetic condition (mutation) where person’s Pancreas cannot make enough insulin (the hormone that brings glucose sugar from the bloodstream into our cells) - usually shows up early in life 3 – 10 y.o. - Glucose in blood builds up and becomes toxic to organs - Causes serious circulatory problems and organ failure 2. Type II - Adult or adolescent (early onset) - Often caused by too much sugar in diet - Pancreas needs to work too hard and eventually the cells that make Insulin “wear out” - Becoming very common due to highsugar diets since 1970 *In both types, patient will need to closely monitor blood sugar and inject Insulin supplements to survive* Nervous System Parts: Neurons / Nerves – Nerve Cells Peripheral (PNS)Sensory and Motor Nerves Central (CNS)Spinal Chord and Brain Functions: 1. Sensing the outside world 2. Carry electrical signals to monitor and effect organ and tissue function to maintain Homeostasis 3. Memory and Personality Synapse- the connection over the gap between neurons. Parts and Functions of the Human Brain Spinal Cord -Relays messages between the Outside World and the Brain, Reflexes Brainstem including Medulla Oblongata - Involuntary Functions including breathing and heart rate, temperature Cerebellum - Balance and Physical Coordination, Vision Cerebrum - Thinking, Learning, Personality, Memory Anatomy of the Human Brain Hand on a Hot Stove1. Sensory Nerves register the heat and pain -> 2. Peripheral Nervous System (PNS) Sensory Neurons carry message to Brain via Spinal Cord (Central Nervous System CNS) 3. CNS processes the message 4. CNS sends message down PNS Motor Neurons to arm muscles 5. Flex Muscles - Pull hand off stove 6. Build a Memory!!!