Download Multiple, Comprehensive Anti

by
Dr. Richard Lippman
formerly with
Departments of Histology and Medical Cell Biology, Uppsala
University, Uppsala, Sweden
Currently affiliated with Profound Nutrition Ltd., UK
Top audiographs show hearing loss due to aging. Bottom
audiographs: When volunteers sprayed 125 mcg aldosterone
into each ear canal, hearing improved by about 33% after 2
hours due to good bioavailability in the cochlea.
15,000 hair cells are divided
into 5 rows in the cochlea
In mice, a wide range of substances are
known to increased blood flow in the
cochlea. Note the untreated CBS arteries in
center versus the treated CBS + FA arteries
on the far right. reference: Kuni, S. et. al., Feb. 2012, Hearing
Research, 284(1-2), pp. 42-51.
Top audiographs show hearing loss due to aging. Bottom
audiographs: When volunteers sprayed 125 mcg aldosterone
into each ear canal, hearing improved by about 33% after 2
hours due to good bioavailability.
Low aldosterone may be seen as a
biomarker of aging and cause of some
types of hearing loss.
Hearing improves by spraying or
injecting IGF-1, dexamethasone,
or aldosterone.
Natural aldosterone improves
hearing by up to 30 decibels
Top audiographs show hearing loss due to aging. Bottom
audiographs: When volunteers sprayed 125 mcg aldosterone
into each ear canal, hearing improved by about 33% after 2
hours due to good bioavailability.
Vasopressin & oxytocin are
hypothalamic hormones made in the
supra-optic and paraventricularnucleus cells
In the Lancet, 1979, Gold et. al. found that
vasopressin improves processing of
information. In a double-blind, placebocontrolled trial, three-fourths of patients
showed “highly significant and consistent
improvements in tests designed to measure
the formation, encoding, and organization
of long-term trace events in memory.”
In 1997, Perras et. al. used 40 IU
vasopressin in 26 healthy elderly
men for 3 months. They found that
vasopressin improves sematic
encoding after long-term use.
At age 54, actor Sean Penn has
vasopressin deficiency signs of
crow’s feet, sunken eyes, blank
stare, and double eyelid fold
The End
In 1982 and 1983, Laczi et. al. found
that diabetic patients injected or
treated intranasally with vasopressin
showed normalization of their
deficits in short- and long-term
memory.
In 1984, Nebes et. al. conducted a
double-blind crossover study and
subjects showed improved longterm retrieval time but did not
benefit in short-term memory due
to the extreme and un-physiologic
daily dose of 60 mg vasopressin
In 1985, researchers Till and
Beckwith concluded that a
vasopressin analog “improved
immediate memory for low-verbal
subjects, but delayed memory for
high-verbal subjects.”
In 1987, Hamburger-Bar et. al.
discovered that childhood learning
disorders may benefit from
repeated doses of vasopressin
In 1987, Millar et. al. found that
in healthy male volunteers,
“vasopressin benefited initial
processes of consolidation and
learning.”
In 1998, Van Londen et. al.
confirmed that the neuropeptide
vasopressin “enhances memory,
directly or indirectly, through
arousal and attention.”
In 1999, Perras et. al. give 26 healthy
elderly subjects 20 IU vasopressin
intranasally for 3 months. Results showed
that vasopressin increased total sleep
time by an average of 45 minutes, slowwave sleep time by 21 minutes, and REM
sleep time by 10 minutes.
In 2002, Neveus et. al. found that
ten children responded positively
to desmopressin (synthetic
vasopressin), and they gained
more REM during sleep.
In 2003, Perras et. al. found in 26
elderly men that arginine
vasopressin (bioidentical) promoted
only improved slow- wave sleep and
the neuroendocrine pattern of
sleep.
In 2003, Lose et. al. found in 144
female patients that desmopressin
is an effective and well-tolerated
treatment for nocturia.