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Name: _______________________________________________________Date: ____________________ Period:______
Biology Notes: Biochemistry
Directions: Fill this out as we cover the following topics in class

Part I. Water
Water Basics
 Polar: part of a molecule is slightly _________________, while another part is slightly
____________________
 Oxygen “hogs” ________________ from hydrogen; results in __________________
charge on oxygen and _______________ charge on hydrogen
 Creates ________________ bonds where on water sticks to another
Water Properties
 High specific heat: Resists temp changes
- much _______________ is needed to break water bonds
- helps to maintain a constant __________ temp
 Cohesion
- polar water molecules attracted to other ___________ water molecules
 Adhesion
- polar water sticks to other __________________
Solutions
 Solution: ______________ where one substance dissolves in another
 2 parts to a solution
1. _________________: substance that dissolves (atom, ions, ____________________)
2. ____________________: substance in which the solute is dissolved (usually _______________)
- ex: human blood: solvent is _______________ (watery part of blood) and ____________________
are carbs, proteins, sugars, etc.
pH Scale

pH scale measure the amount of __________ in a solution

1 minute: Discuss with your neighbor: A) Which base has the most H+ ions? ____________ B) Which substance
has the fewest H+ ions? ____________________ C) Which is the strongest acid? __________________




Some molecules release H+ ions when dissolved  ______________ (pH= _____________)
Some molecules release _______ (hydroxide) ions when dissolved  ______________ (pH= _____________)
Solution is _______________ when H+ = OH- (pH= _________)
pH balance is vital to life. Ex: Blood pH (7.4): ______________________ break down outside normal pH
Review
1) Vocabulary: Polar, Adhesion, Cohesion, High Specific Heat, Solution, Solute, Solvent, pH
2) Name 4 basic features of water.
3) Which water property explains that one atom is positively charged, while another is negatively charged?
4) How does cohesion and adhesion differ?
5) Which is a stronger acid? Substance A with a pH of 5 or substance B with a pH of 3?
6) Which has more H+ ions? Substance A with a pH of 5 or substance B with a pH of 3?
7) Which has more OH- ions? Substance A with a pH of 5 or substance B with a pH of 3?
8) How does a solute differ from a solvent?
9) What is the solute and solvent of blood?
Part II. Organic Molecules
A. Organic Molecules
 Carbon = building block of organic molecules (____________________________)
 Carbon is unique
- 2nd electron level __________________ full
- Only has ___________ electrons in 2nd level
- Will bond up to ______________ times
 Monomer: __________________ carbon molecules
- Ex: Amino acid
 Polymer: ___________________ of linked ___________________
- Ex: Protein
Carbon creates 4 bonds to be stable
Draw stable C & H compound.
 Is Carbon stable with 4 electrons in its outer layer? ___________
 Is Hydrogen stable with 1 electron in its layer? __________
 So what do atoms do when they are unstable? _____________
B. Carbohydrates
 Readily available food source
 C_____: H _____: O _____ ratio
- Ex: ______________________= C6H12O6
 Monomer: ________________________
- Simple sugars
- Bond to form __________________ sugars
 Polymer: __________________________
- Complex sugars
Carbohydrate Polymers: ___________________________
 ___________________ chain of monosaccharides
 Ex: Starch: excess _______________ sugar converted & stored
 Ex: Glycogen: starch made by ___________________; stored in ___________________& muscles
 Ex: Cellulose: starch made by ___________________; stored by plants to make ______________________
Review Carbohydrates
1) How many electrons does Carbon have in the 1st energy level? 2nd energy level?
2) Which type of organic molecule is most commonly used as energy for cells?
3) If a carbohydrate has 8 carbon atoms, how many oxygen and hydrogen atoms will it most likely have?
4) What are the monomers of carbohydrates called?
5) Which polymer of carbohydrates is stored by animals?
6) Which polymer of carbohydrates is stored by plants?
C. Lipid Structure
 Fats, Oils, Cholesterol, Waxes
 Monomer: _______________________
 Polymer: ________________________
 Phospholipid:
- Structure (3 parts):
o “Head” = _____________________&________________________
o “Tails” = ______________Fatty acids
 Trigylceride:
- Structure (2 parts):
o “Head” = Glycerol
o “Tails” = 3 Fatty Acids
 Function: Provide ___________________ for cells, insulation
- Cholesterol: Gives cell membrane _______________________
Saturated Fatty Acids
 Long chain of C-C bonds (all ______________________bonds)
 Each ____________________ is “saturated” with _______________
atoms
- Common in __________________ fats
 Health Alert!
- Solid at room temps; more likely to clog veins
Unsaturated Fatty Acids
 Chain with C=C bonds (_________________ bonds)
- Double bonds ___________________ H from attaching
- Double bonds makes the chain __________________________
 Unsaturated: ____________________ space for H atoms
- Common in ___________________
 Health Alert:
- Liquid at room temps; Less likely to clog veins
Review Lipids
1) What are the three parts of a phospholipid called?
a. Which part is the “head”?
b. Which part are the “tails”? How many?
2) What are the 2 parts of a triglyceride called?
a. Which part is the “head”?
b. Which part are the “tails”? How many?
3) How do saturated and unsaturated fatty acids differ?
4) Which lipid gives cells their flexibility?
5) Why are saturated fats less healthy?
D. Nucleic Acid Basics
 Contains instructions to build __________________
 Two types: - ________________ - ________________
 Composed of smaller units called _____________________
- Monomer: ______________________
- Polymer: ________________________
Nucleotide Structure
 Three parts
Draw a nucleotide.
- ____________________________________
- ____________________________________
- ____________________________________
 Nucleotides combine to make ________________________________
 Instructions for ________________ to make __________________
Monomers link to make Polymers!
 Nucleic Acids
- Monomer: _______________________ - Polymer: ______________________
 How many nucleotides are pictured? _______ What is this chain of nucleotides called? __________________
DNA
 Double Helix: ______________ chains of nucleotides
 Four DNA bases: Adenine, Thymine, Cytosine, Guanine
- A pairs with ___________ & __________ pairs with G
 Gene: _________________ of DNA that __________________ for a _________________________
RNA
 ________________ chain of nucleotides
 RNA bases: Adenine, ___________________, Cytosine, Guanine
 Function: Help cells with the creation of ________________________
Review Nucleotides
1) Name the polymer of nucleotides.
2) Draw and label a nucleotide.
3) How are the four nitrogen bases of DNA abbreviated?
4) What does the phosphate molecule of a nucleotide bond with?
5) What do you call a section of DNA that codes for a protein?
6) If the DNA nitrogen bases were TACCGGAT, how would the attached DNA strand read?
7) How are DNA and RNA different?
E. Protein Basics
 Used in a variety of ____________________ functions
 Made of smaller amino acids
- Monomer: _________________________________
- Polymer: _________________________________
 Only _________ amino acids… but __________________ of proteins
- Exact _______________ of amino acids _____________________
the protein
Amino Acid Structure
 5 basic parts
1) Central __________________ atom
2) ____________________ group (NH2)
3) __________________
4) ____________________ group (COOH)
5) ______________ group
 What differs between amino acids? ___________________________
Review Proteins
1) What are the smaller monomers that make proteins called?
2) How many different amino acids exist?
3) How does each amino acid differ?
4) The NH2 part of the amino acid is called the ______ group.
5) The COOH part of the amino acid is called the ______ group.
Part III. Chemical Reactions


Change substance into different one by breaking and forming ______________________________
- Reactants are the substances ___________________ during a chemical reaction
- Products are the substance _______________ by a chemical reaction
Activation Energy: amount of energy needed to _____________ a reaction
Controlled Settings
 Human body ~ 98.6F
- Can’t raise body temp to start reactions
 Internal reactions would be too slow to sustain life without a ______________________
 Ex: Saliva: Breaks down starch _________________x faster with amylase
How do Enzymes Help?
 Activation energy usually comes from an increase in temp
- ___________ process
 Catalyst: substance that decreases the _____________________ energy needed to start a chemical reaction
- ___________________ reaction
 Enzymes reduce energy needed (activation energy) to start a chemical reaction and increases reaction rate
Enzymes
 Enzyme shape allows specific ____________________ to bind together
- Reactants = ___________________
- Ex: Amylase & starch: Starch is the __________________ because it binds to __________________
 Substrates bind to ___________________ sites on the enzyme (_________ fitting into ____________)
 Once bonded to enzyme, substrates bonds _______________ and break
 Substrates re-bond to each other and a new _________________ is formed.
 Catalyst is _______________________
 Type of ____________________ so sensitive to _______________, _________________, _________________
- Ex: If a high fever: enzymes lose ability to work
Review
1)
2)
3)
4)
5)
6)
How do enzymes speed up chemical reactions?
What are the molecules called that react with enzymes?
Given the following chemical formula list the products and reactants: 6O2 + C6H12O6  6CO2 + 6H2O
What are the substances that are changed during a chemical reaction called?
What is another term for a catalyst?
Why can’t the human body raise its temperature to allow chemical reactions to happen quicker?