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Rheumatoid arthritis Major Products of Mitsubishi Tanabe Pharma Group A cytokine (substance present within the body) known as TNFα is involved in rheumatoid arthritic inflammation. A biological drug, Remicade, is used in the treatment of this ailment and its therapeutic effects have drawn considerable attention. Remicade “ Methotrexate tablets Tanabe” Cerebral circulation These products are mainly used in treatment during the acute phase of a cerebral infarction (stroke). Currently, the types of drugs used in Japan during the acute phase of cerebral infarction include thrombolytic drugs, cerebroprotective drugs, and selective thrombin inhibitors. Radicut Hypertension and heart disease Peripheral circulation Antihypertensive drugs are used in the treatment of high blood pressure. Divided into several categories depending on their efficacy and side effects, these products are prescribed to treat specific symptoms. Arteriosclerosis and diabetes cause poor peripheral circulation, which may lead to pain, coldness, and ulceration on the hands and feet. These products improve circulation and the above symptoms by expanding peripheral blood vessels and thinning the blood to reduce the likelihood of blood clots. Tanatril Maintate Herbesser Anplag Liple Allergies Disorders of the digestive system Allergic rhinitis and bronchial asthma are caused by hypersensitivity of the immune system, which triggers allergic reactions. These products suppress disease-specific allergic reactions and improve symptoms. These products are used to treat gastritis and gastric ulcers by suppressing the secretion of stomach acid and protecting the gastric mucosa. Urso is used in the treatment of liver disease, reducing damage to liver cells by replacing bile acid and improving liver function. Talion 08 Grtpa Novastan Theodur Mitsubishi Tanabe Pharma Corporation CSR Report 2011 Urso Omeprazon Gastrom Cerekinon Central nervous system Infectious diseases The central nervous system comprises the brain and spinal cord, and controls sensation, movement, thinking, emotions, reactions, breathing, and all other physical activities. These products are used to treat diseases of the central nervous system, such as insomnia, depression, spinocerebellar degeneration, and narcolepsy. The immune systems of elderly people or post-operative patients are weakened, leaving them liable to serious bacterial and viral infections. The following antibacterial and antiviral agents are used in these cases. Doral Depas Ceredist Modiodal Pazucross Valixa Denosine Vaccines Vaccines are agents made from weakened or killed forms of pathogens or their toxins. Being inoculated with a vaccine causes the body to produce antigens specific to the pathogen in the vaccine, which helps protect the body from infection by the pathogen. Mearubik Flubik HA Varicella Vaccine Live “ Attenuated Biken” Plasma fractionation products IV solutions Plasma fractionation products are pharmaceuticals that are derived from the human blood component known as plasma and are manufactured by breaking down and refining useful proteins. Because they are made from human blood, a variety of safety measures are in place to ensure product safety. These products are used for intravenous infusions, which are used to provide lost fluids supplementally, electrolytes, and nutrients in cases when patients cannot take food by mouth or are dehydrated due to diarrhea or vomiting. Venoglobulin-IH 5% Neuart Donated blood albumin 25% Fulcaliq Unicaliq Amigrand Generic drugs Over-the-counter drugs Generic drugs can be launched after the patent expiration of the respective drug. Building on its superior track record as a manufacturer of new drugs, Mitsubishi “ Tanabe Pharma markets safe generic drugs under the slogan, Reliable Generics.” Over-the-counter (OTC) drugs are available at pharmacies and drug stores without a doctor’s prescription. These OTC drug products allow users to manage personal health and treat simple physical ailments. “ Pioglitazone Tanabe” Alositol “ Amlodipine Tanabe” Aspara drinks Flucort F skin ointment Nan Pao herbal medicine Mitsubishi Tanabe Pharma Corporation CSR Report 2011 09