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CURRICULUM VITAE Name: Kristina Irsch, Ph.D. DEMOGRAPHIC AND PERSONAL INFORMATION Current Appointments Assistant Professor of Ophthalmology The Wilmer Eye Institute The Johns Hopkins University School of Medicine Baltimore, Maryland Personal Data Business address: Phone: E-mail: Date of Birth: Place of Birth: Citizenship: Wilmer 233 The Johns Hopkins Hospital 600 North Wolfe Street Baltimore, Maryland 21287-9028 (443) 858-4255 [email protected] April 24, 1982 Merzig (Saarland), Germany German; U.S. Permanent Resident (“green card”) since May, 2012 EDUCATION AND TRAINING 2003 2005 – 2006 2006 2007 2007 – 2008 2008 Pre-diploma (“Vordiplom”) in Physics, University of Heidelberg, Heidelberg, Germany. Graduate research in Medical Physics (Biomedical Optics), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Master of Science (M.S.) in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Diploma (“Diplom,” equivalent of Master’s degree) in Physics, University of Heidelberg, Heidelberg, Germany. Graduate research in Physics (Ophthalmic Optics), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Ph.D. (“Dr. rer. nat.”) in Physics (Thesis advisor: Josef Bille, Ph.D.), University of Heidelberg, Heidelberg, Germany. Page 1 of 14 Curriculum Vitae – January 2014 2009 – 2010 Kristina Irsch, Ph.D. Postdoctoral research fellowship in Ophthalmology – Ophthalmic Instrumentation/Strabismus and Pediatric Ophthalmology (David L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. SPECIAL TRAINING 09/2005 09/2005 05/2009 07/2009 Workshop on Ophthalmic Optics, Moorfields Eye Hospital and the UCL Institute of Ophthalmology, London, United Kingdom. Workshop on Nuclear Medicine and Advanced Image Data Analysis, Shanghai Jiao Tong University, Shanghai, China. Photon Engineering’s Principles of Stray Light Short Course, Tucson, Arizona. Photon Engineering’s FRED Optical Engineering Software Tutorial, Tucson, Arizona. PROFESSIONAL EXPERIENCE 04/2004 – 09/2005 10/2007 – 12/2007 10/2008 – 12/2008 06/2010 – present Assistant for Accelerator Operation (“Hilfsoperateur”), Max Planck Institute for Nuclear Physics, Heidelberg, Germany. Research Associate (“Wissenschaftlicher Mitarbeiter”) in the position of a Teaching Assistant, School of Medicine of the University of Heidelberg at Mannheim, Germany. Research Associate (“Akademischer Mitarbeiter”) in the position of a Teaching Assistant, School of Medicine of the University of Heidelberg at Mannheim, Germany. Assistant Professor of Ophthalmology, The Krieger Children’s Eye Center at The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland. RESEARCH ACTIVITIES Publications: Peer-reviewed scientific articles 1. Agopov M, Gramatikov BI, Wu YK, Irsch K, Guyton DL. Use of retinal nerve fiber layer birefringence as an addition to absorption in retinal scanning for biometric purposes. Applied Optics 2008; 47(8): 1048-1053. 2. Ramey NA, Ying HS, Irsch K, Müllenbroich MC, Vaswani R, Guyton DL. A novel haploscopic viewing apparatus with a three-axis eye tracker. Journal of the American Association for Pediatric Ophthalmology and Strabismus 2008; 12(5): 498-503. Page 2 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. 3. Irsch K*, Ramey NA, Kurz A, Guyton DL, Ying HS. Video-based head movement compensation for novel haploscopic eye tracking apparatus. Investigative Ophthalmology & Visual Science 2009; 50(3): 1152-1157. *Corresponding author 4. Babar S, Khare GD, Vaswani RS, Irsch K, Mattheu JS, Walsh L, Guyton DL. Eye dominance and the mechanisms of eye contact. Journal of the American Association for Pediatric Ophthalmology and Strabismus 2010; 14(1): 52-57. 5. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Modeling and minimizing interference from corneal birefringence in retinal birefringence scanning for foveal fixation detection. Biomedical Optics Express 2011; 2(7): 1955-1968. *Corresponding author 6. Irsch K*, Shah AA. Birefringence of the central cornea in children assessed with scanning laser polarimetry. Journal of Biomedical Optics 2012; 17(8): 086001. *Corresponding author 7. Deng H, Irsch K*, Gutmark R, Phamonvaechavan P, Foo F, Anwar DS, Guyton DL. Fusion can mask the relationships between fundus torsion, oblique muscle overaction/underaction, and A- and V-pattern strabismus. Journal of the American Association for Pediatric Ophthalmology and Strabismus 2013; 17(2): 177-183. *Corresponding author 8. Irsch K*, Guyton DL, Ramey NA, Adyanthaya RS, Ying HS. Vertical vergence adaptation produces an objective vertical deviation that changes with head tilt. Investigative Ophthalmology & Visual Science 2013; 54(5): 3108-3114. *Corresponding author 9. Gramatikov B, Irsch K, Müllenbroich M, Frindt N, Qu Y, Gutmark R, Wu K, Guyton D. A device for continuous monitoring of true central fixation based on foveal birefringence. Annals of Biomedical Engineering 2013; 41(9): 1968-1978. 10. Muthusamy B, Chang HP, Irsch K, Muthusamy K, Anwar DS, Ying HS, Guyton DL. Differentiating bilateral superior oblique paresis from sensory extorsion. Journal of the American Association for Pediatric Ophthalmology and Strabismus 2013; 17(5): 471476. 11. Muthusamy B, Irsch K, Chang HP, Guyton DL. The sensitivity of the Bielschowsky head tilt test in diagnosing acquired bilateral superior oblique paresis. American Journal of Ophthalmology 2014 Jan 9; doi: 10.1016/j.ajo.2014.01.003. [Epub ahead of print] 12. Adyanthaya RS, Broome S, Muthusamy B, Irsch K, Klein KS, Guyton DL. Down syndrome and accommodation: The added advantage of bifocals. Journal of the American Association for Pediatric Ophthalmology and Strabismus (in press). Publications: Dissertation Irsch K. Polarization modulation using wave plates to enhance foveal fixation detection in retinal birefringence scanning for pediatric vision screening purposes. Dissertation (Ph.D. thesis) 2009. University of Heidelberg. URL: http://www.ub.uniheidelberg.de/archiv/8938/ Page 3 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. Publications: Conference proceedings 1. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Spinning wave plate design for retinal birefringence scanning. Proceedings of Society of Photo-Optical Instrumentation Engineers SPIE 2009; 7169: 71691F1-12. *Corresponding author 2. Irsch K, Guyton DL, Li N, Ying HS. Cyclovertical fusion patterns after vertical vergence adaptation in normals are different from those in some patients with superior oblique paresis. Annals of the New York Academy of Sciences 2011; 1233: Supplementary file. URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2011.06222.x/suppinfo 3. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Wave-plate-enhanced retinal birefringence scanning for true foveal fixation detection. Imaging and Applied Optics Technical Papers, OSA Technical Digest (online) (Optical Society of America, 2012), paper IM3C.4. *Corresponding author 4. Irsch K*, Guyton DL, Park HS, Ying HS. Different mechanisms of motor fusion may differentiate between patients with true, versus masquerading, superior oblique paresis. Transactions 34th European Strabismological Association (in press). *Corresponding author 5. Irsch K*, Guyton DL, Ying HS. Objective analysis of the mechanism of vertical fusional vergence to classify “congenital superior oblique paresis” and guide surgical approach. Transactions 35th European Strabismological Association (in press). *Corresponding author 6. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus detection and double-pass focus detection. Imaging and Applied Optics, J. Christou and D. Miller, eds., OSA Technical Digest (online) (Optical Society of America, 2013), paper ITh2D.5. *Corresponding author Oral Presentations and Published Abstracts 1. Ying HS, Irsch K, Ramey NA, Zee DS, Guyton DL. Vertical vergence adaptation decreases ocular counter roll gain. Neuroscience 2008 – The 38th annual meeting of the Society for Neuroscience, November 2008, Washington, D.C. 2. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Optimized retinal birefringence scanning using wave plates for strabismus screening. 20th Annual Wilmer Research Meeting, April 2009, Baltimore, Maryland. 3. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Polarization modulation using wave plates to enhance foveal fixation detection in retinal birefringence scanning for strabismus screening purposes. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2009, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2009; 50: E-Abstract 4755. 4. Irsch K, Guyton DL, Roggia M, Ying HS. Can patients with superior oblique paresis mimic the neural output of the ocular counter-roll mechanism to fuse vertically? 36th American Association for Pediatric Ophthalmology and Strabismus (AAPOS) Annual Page 4 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. Meeting, April 2010, Orlando, Florida. Abstract published in Journal of AAPOS 2010; 14(1): e4, 14. 5. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. How can patients maintain binocular fusion in the presence of superior oblique paresis? XVIII International Neuro-Ophthalmology Society (INOS) meeting, June 2010, Lyon, France. Abstract published in Neuro-ophthalmology 2010; 34(3): VI-O 6, 206. 6. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may differentiate between patients with true superior oblique paresis (SOP) and those with masquerading SOP. 10th European Neuro-Ophthalmology Society (EUNOS) meeting, June 2011, Barcelona, Spain. Abstract published in Neuro-ophthalmology 2011; 35(S1): S21. 7. Irsch K, Guyton DL, Park HS, Ying HS. Different fusional mechanisms may distinguish patients with true superior oblique paresis (SOP) from those that masquerade as SOP. 34th European Strabismological Association (ESA) meeting, September 2011, Bruges, Belgium. 8. Irsch K, Guyton DL, Ying HS. Classifying “congenital superior oblique paresis” using an objective measure of vertical fusional vergence. XIX International NeuroOphthalmology Society (INOS) meeting, June 2012, Singapore. Abstract published in Neuro-ophthalmology 2012; 36(S1): 7. 9. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Wave-plate-enhanced retinal birefringence scanning for true foveal fixation detection. Optical Society of America (OSA) Imaging Systems and Applications (IS) meeting, Imaging and Applied Optics: OSA Optics and Photonics Congress, June 2012, Monterey, California. 10. Irsch K, Guyton DL, Ying HS. Objective analysis of the mechanism of vertical fusional vergence to classify “congenital superior oblique paresis” and guide surgical approach. 35th European Strabismological Association (ESA) meeting, September 2012, Bucharest, Romania. 11. Irsch K, Ying HS, Guyton DL. Fusion influences the Bielschowsky head tilt test in superior oblique paresis. 39th North American Neuro-Ophthalmology Society (NANOS) annual meeting, February 2013, Snowbird, Utah. 12. Irsch K, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus detection and double-pass focus detection. Optical Society of America (OSA) Imaging Systems and Applications (IS) meeting, Imaging and Applied Optics: OSA Optics and Photonics Congress, June 2013, Arlington, Virginia. 13. Irsch K, Ying HS, Guyton DL. Lingering fusional adaptation influences the Bielschowsky head tilt test in superior oblique paresis. 36th European Strabismological Association (ESA) meeting, September 2013, Marseilles, France. Poster Presentations and Published Abstracts 1. Ying HS, Ramey NA, Müllenbroich MC, Irsch K, Guyton DL. Basic cyclovertical deviation and superior oblique palsy have similar head tilt behavior. American Academy of Ophthalmology (AAO) Annual Meeting, November 2006, Las Vegas, Nevada, EAbstract P0624. Page 5 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. 2. Adyanthaya RS, Ying HS, Ramey NA, Müllenbroich MC, Irsch K, Guyton DL. A novel haploscopic viewing apparatus with a three-axis eye tracker. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2007, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2007; 48: E-Abstract 897. 3. Ying HS, Irsch K, Vaswani R, Kurz A, Ramey NA, Adyanthaya RS, Zee DS, Guyton DL. Ocular counter-roll is decreased after vertical vergence adaptation. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2008, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2008; 49: E-Abstract 1802. Also presented at the XXV Bárány Society Meeting, April 2008, Kyoto, Japan. 4. Irsch K, Ying HS, Kurz A, Ramey NA, Adyanthaya RS, Guyton DL. Head movement compensation for novel haploscopic eye tracking apparatus. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2008, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2008; 49: E-Abstract 1803. 5. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Polarization modulation improves retinal birefringence scanning. Optical Society of America (OSA) Vision Meeting, October 2008, Rochester, New York. Abstract published in Journal of Vision 2008; 8(17): 61, 61a, http://journalofvision.org/8/17/61/, doi:10.1167/8.17.61. 6. Ying HS, Irsch K, Ramey NA, Guyton DL. Vertical vergence adaptation produces a transient cyclovertical deviation changing with head tilt. 35th American Association for Pediatric Ophthalmology and Strabismus (AAPOS) Annual Meeting, April 2009, San Francisco, California. Abstract published in Journal of AAPOS 2009; 13(1): e32, 127. 7. Ying HS, Irsch K, Ramey NA, Guyton DL. Vertical vergence adaptation produces an incomitant transient cyclovertical deviation changing with gaze direction and head tilt. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2009, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2009; 50: E-Abstract 1990. 8. Ying HS, Irsch K, Guyton DL. Cyclovertical vergence in individuals with superior oblique paresis is similar with attempted fusion or with head tilt. Neuroscience 2009 – The 39th annual meeting of the Society for Neuroscience, October 2009, Chicago, Illinois. 9. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. Can patients with superior oblique paresis mimic the neural output of the ocular counter-roll mechanism to fuse vertically? Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2010, Fort Lauderdale, Florida. Investigative Ophthalmology & Visual Science 2010; 51: E-Abstract 2534. 10. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. Mechanisms of binocular fusion in patients with superior oblique paresis. World Ophthalmology Congress (WOC), June 2010, Berlin, Germany, Abstract P-SA-226. 11. Ying HS, Guyton DL, Li N, Irsch K. Subjects after adaptation to cyclovertical deviation or with superior oblique paresis use opposite movements to fuse vertically. Basic and Page 6 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. Clinical Ocular Motor and Vestibular Research meeting, March 2011, Buenos Aires, Argentina. 12. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may distinguish patients with true superior oblique paresis (SOP) from those that masquerade as SOP. 22th Annual Wilmer Research Meeting, April 2011, Baltimore, Maryland. 13. Doyle J, Purdy C, Tabibian D, Irsch K, Tarczy-Hornoch K, Braunstein K, Guyton DL. Modified retinoscope to measure refractive error in Marfan syndrome mice. 22th Annual Wilmer Research Meeting, April 2011, Baltimore, Maryland. 14. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may distinguish patients with true superior oblique paresis (SOP) from those with masquerading SOP. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2011, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2011; 52: E-Abstract 4698. 15. Gramatikov B, Irsch K, Guyton D. A monocular device for continuous monitoring of central fixation using retinal birefringence scanning. Metropolitan Biophotonics Symposium, March 2012, Baltimore, Maryland. 16. Ying HS, Geary RB, Irsch K. Visual and post-saccadic potentiation of ocular counter roll gain results in near-stabilization of retinal images. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2012, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science 2012; 53: E-Abstract 4871. Also presented at Neuroscience 2012, October 2012, New Orleans, Louisiana. 17. Irsch K, Shah A. Central corneal birefringence in children assessed with scanning laser polarimetry. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2012, Fort Lauderdale, FL. Abstract published in Investigative Ophthalmology & Visual Science 2012; 53: E-Abstract 3616. Also presented at the 23rd Annual Wilmer Research Meeting, April 2012, Baltimore, Maryland. 18. Muthusamy B, Irsch K, Chang P, Guyton DL. The sensitivity of the Bielschowsky head tilt test in diagnosing bilateral superior oblique paresis. 39th American Association for Pediatric Ophthalmology and Strabismus (AAPOS) Annual Meeting, April 2013, Boston, Massachusetts. Abstract published in Journal of AAPOS 2013; 17(1): e24, 85. 19. Irsch K, Ying HS, Guyton DL. The influence of fusion on the Bielschowsky head tilt test in superior oblique paresis. 11th European Neuro-Ophthalmology Society (EUNOS) meeting, April 2013, Oxford, United Kingdom. Abstract published in Neuroophthalmology 2013; 37(S1): 93-94. 20. Geary RB, Ying HS, Irsch K. Quick phase of the torsion vestibulo-ocular reflex increases the gain of the slow phase both before and after the quick phase. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 181. 21. Irsch K, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus detection and double-pass focus detection. Association for Research in Vision and Page 7 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 3986. 22. Gramatikov BI, Irsch K, Guyton DL. Pupil size dynamics during the first minutes of dark adaptation while fixating on a target. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 4374. 23. Deschler EK, Irsch K, Guyton KL, Guyton DL. Adjustable-suture strabismus surgery: A new, removable, sliding noose. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 4711. 24. Muthusamy B, Adyanthaya R, Broome S, Irsch K, Klein K, Guyton DL. Down syndrome and accommodation: The added advantage of bifocals. Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 5684. Inventions, Patents (pending, awarded) 1. Gramatikov BI, Guyton DL, Irsch K. Method and apparatus for detecting fixation of at least one eye of a subject on a target. Invention disclosure (Ref. No. C11459) submitted to the Johns Hopkins University Technology Transfer, 8 March 2011. U.S. Provisional Patent Application (No. 61/450,996) filed in the U.S. Patent and Trademark Office, 9 March 2011. U.S. Patent Application (No. 13/416,979) filed in the U.S Patent Trademark Office, 9 March 2012; published, 13 September 2012 (Pub. No.: US 2012/0229768 A1). 2. Gramatikov BI, Guyton DL, Irsch K. Eye fixation system and method. Invention disclosure (Ref. No. C12166) submitted to the Johns Hopkins University Technology Transfer, 13 September 2012. U.S. Patent Application (No. 13/773,307) filed in the U.S Patent Trademark Office, 20 February 2013. 3. Ying HS†, Irsch K†, Guyton DL, Geary R, Gramatikov BI, Simons K. Method and apparatus for detection of microstrabismus and stability of fixation in at least on eye to screen for or diagnose amblyopia. Invention disclosure (Ref. No. C12286) submitted to the Johns Hopkins University Technology Transfer, 21 December 2012. †Equal contributions 4. Irsch K, Guyton DL, Gramatikov BI. Apparatus and method for minimizing the influence of corneal birefringence on the analysis of eye fixation and focus using retinal birefringence scanning. Invention disclosure (Ref. No. C12406) submitted to the Johns Hopkins University Technology Transfer, 14 March 2013. U.S. Provisional Patent Application (No. 61/793,350) filed in the U.S. Patent and Trademark Office, 15 March 2013. 5. Gramatikov BI, Guyton DL, Irsch K. Eye tracking and gaze fixation detection systems, components and methods using polarized light. Invention disclosure (Ref. No. C12498) submitted to the Johns Hopkins University Technology Transfer, 19 April 2013. U.S. Provisional Patent Application (No. 61/823,738) filed in the U.S. Patent and Trademark Office, 15 May 2013. Page 8 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. 6. Gramatikov BI, Guyton DL, Toth CA, Izatt JA, Carrasco-Zevallos O, Irsch K. Method and system for improving aiming during optical coherence tomography on young children by synchronization with retinal birefringence scanning. Invention disclosure (Ref. No. C12709) submitted to the Johns Hopkins University Technology Transfer, 16 September 2013. U.S. Provisional Patent Application (No. 61/885,794) filed in the U.S. Patent and Trademark Office, 2 October 2013. Extramural Funding (current, pending, previous) 09/2008 – 11/2014 NIH R01 EY019347 Ocular Motor Adaptation in Health and Disease Principal Investigator: Howard S. Ying, M.D., Ph.D. Role: Co-Investigator 07/2009 – 06/2010 Knights Templar Eye Foundation Young Investigator Award Optimized Retinal Birefringence Scanner for Strabismus Screening Role: Principal Investigator 04/2010 – 03/2013 Hartwell Foundation Biomedical Research Award Pediatric Vision Screening Instrument for Early Detection of Amblyopia (‘Lazy Eye’) Principal Investigator: Boris I. Gramatikov, Ph.D. Role: Co-Investigator 06/2012 – 05/2013 RPB Walt and Lilly Disney Award for Amblyopia Research Detection of Microstrabismus and Stability of Fixation in Amblyopia Principal Investigator: Howard S. Ying, M.D., Ph.D. Role: Co-Investigator 12/2012 – 11/2014 Hartwell Foundation Biomedical Research Collaboration Award Diagnosis and Management of Infant Retinal Disease: Fast Swept Source Optical Coherence Tomography Synchronized with Central Fixation Principal Investigator: Cynthia A. Toth, M.D., Boris I. Gramatikov, Ph.D. Role: Co-Investigator EDUCATIONAL ACTIVITIES Educational Publications: Letters, short reports 1. Deschler EK, Irsch K, Guyton KL, Guyton DL. A new, removable, sliding noose for adjustable-suture strabismus surgery. Journal of the American Association for Pediatric Ophthalmology and Strabismus 2013; 17(5): 524-527. Educational Publications: Book chapters, monographs 1. Irsch K, Guyton DL. Anatomy of Eyes. In: Li SZ (Ed.): Encyclopedia of Biometrics. Springer, New York, 2009; 11-16. Page 9 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. 2. Gutmark R, Irsch K, Guyton DL. Prescribing Prisms. Focal Points: Clinical Modules for Ophthalmologists. American Academy of Ophthalmology, 2011; Vol. XXIX, No. 10 (Module 1 of 3). 3. Irsch K, Guyton DL. Anatomy of Eyes. In: Li SZ (Editor): Encyclopedia of Biometrics. 2nd ed. Springer, New York (in press). Teaching: Classroom instruction 2007 – 2008 (annual) Fall 2008 Basic Course in Physics and Optics for Medical Students, as part of the Mannheim Reformed Curriculum for Medicine (MaReCuM) Program, School of Medicine of the University of Heidelberg at Mannheim, Germany. Aberrometry and Wavefront Analysis course, as part of the International Master’s Program in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Teaching: Laboratory instruction 2007 – 2008 (annual) Fall 2008 Course in Optics and Microscopy for Medical Students, as part of the Mannheim Reformed Curriculum for Medicine (MaReCuM) Program, School of Medicine of the University of Heidelberg at Mannheim, Germany. Adaptive Optics Aberrometry and Wavefront Analysis and Confocal Laser Scanning Ophthalmoscopy course, as part of the International Master’s Program in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Teaching: Clinical instruction 2009 – present (annual) First-year ophthalmology resident class orientation: Retinoscopy and subjective refraction practicum, The Wilmer Eye Institute, Baltimore, Maryland. Teaching: Didactic instruction 2012 – present Resident lecture series: Ophthalmic Optics, The Wilmer Eye Institute, (annual) Baltimore, Maryland. 2012 – present Houston Basic Science Course: Ophthalmic Optics, University of Texas, (annual) Houston, Texas. March 11, 2013 The Osler Institute – Ophthalmology Review Course: Optics & Refraction, Chicago, Illinois. November 3-7, 2013 Basic Ophthalmology Course: Ophthalmic Optics, King Khaled Eye Specialist Hospital (KKESH) and King Saud University, Riyadh, Saudi Arabia. Page 10 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. Teaching: CME instruction August 6, 2009 Monocular Fixation Monitor Using Retinal Birefringence Scanning, the Forerunner of the The Pediatric Vision Screener. Demonstration, with Boris I. Gramatikov, Ph.D., National Association of Vision Professionals (NAVP) 2009 Conference, Baltimore, Maryland. August 6, 2009 The Pediatric Vision Screener. Demonstration, with Boris I. Gramatikov, Ph.D. and David L. Guyton, M.D., National Association of Vision Professionals (NAVP) 2009 Conference, Baltimore, Maryland. December 9, 2010 Untwisting screwed-up eyeballs – Exploring superior oblique paresis with a tilting haploscope. Lecture, Pediatric Ophthalmology Grand Rounds, The Wilmer Eye Institute, Baltimore, Maryland. Mentoring: Pre-doctoral 2006 – 2007 2007 – 2008 2008 2009, 2010 2011 Nicole Frindt. Graduate student in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Received M.S. degree for project (entitled “Alignment and testing of a retinal-birefringencescanning-based eye fixation monitor for attention deficit hyperactivity disorder (ADHD) diagnosis and research”) conducted at The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Sonya Babar. Medical student, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Assisted in analysis of ocular counter-roll gain after vertical vergence adaptation with novel haploscopic eye tracking apparatus. Yinhong Qu. Graduate student in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Received M.S. degree for project (entitled “Video-based target system for retinal-birefringencescanning-based eye fixation monitor for attention deficit hyperactivity disorder (ADHD) screening and research”) conducted at The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Gilbert F. Xue. High school sophomore, River Hill High School, Clarksville, Maryland. Assisted in validation of computer model mathematically describing retinal birefringence scanning. Ashesh A. Shah. Graduate student in Medical Physics with Distinction in Radiotherapy and Biomedical Optics, University of Heidelberg and University Hospital in Mannheim, Germany. Received M.S. degree for project (entitled “Birefringence of the central cornea in children measured using scanning laser polarimetry”) conducted at The Wilmer Eye Institute Page 11 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. at The Johns Hopkins University School of Medicine, Baltimore, Maryland). Mentoring: Post-doctoral 2009 2009 – 2010 2010 2012 2013 Pittaya Phamonvaechavan, M.D. Post-doctoral research fellow in Ophthalmology (David L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Murilo Roggia, M.D. Post-doctoral research fellow in Ophthalmology (Howard S. Ying, M.D., Ph.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Ningdong Li, M.D. Post-doctoral research fellow in Ophthalmology (Howard S. Ying, M.D., Ph.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Emily K. Deschler, M.D. Post-doctoral clinical fellow in Ophthalmology (David L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. Brinda Muthusamy Post-doctoral clinical fellow in Ophthalmology (David L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins University School of Medicine, Baltimore, Maryland. ORGANIZATIONAL ACTIVITIES Institutional Administrative Appointments 2011 – present Wilmer Five-o’clock Afternoon Research Meeting (FARM) Organizational Committee Editorial Activities: Editorial board appointments 2011 – present Medical Hypothesis, Discovery and Innovation (MEHDI) Ophthalmology Journal 2012 – present Ophthalmology and Eye Diseases 2013 – present International Journal of Ophthalmology Editorial Activities: Journal peer review activities 2010 – present Clinical Optometry 2011 – present Clinical Ophthalmology 2011 – present Ophthalmology and Eye Diseases 2011 – present Optics Letters 2012 – present Applied Optics 2013 – present Acta Ophthalmologica Page 12 of 14 Curriculum Vitae – January 2014 2013 – present 2013 – present Kristina Irsch, Ph.D. Photonics Research Journal of Biomedical Optics Professional Societies 2002 – present 2005 – present 2006 – present 2007 – present 2007 – present 2009 – present 2009 – present 2009 – present 2011 – present German Physical Society (“Deutsche Physikalische Gesellschaft,” DPG) Association of Scholarship-Holders and Friends of the BadenWürttemberg-STIPENDIUM (“Verein der Stipendiaten und Freunde des Baden-Württemberg-STIPENDIUMs”) Association for Research in Vision and Ophthalmology (ARVO) Optical Society of America (OSA) Society of Photo-Optical Instrumentation Engineers (SPIE) American Association for the Advancement of Science (AAAS) German Society of Applied Optics (“Deutsche Gesellschaft für angewandte Optik,” DGaO) European Optical Society (EOS) European Neuro-Ophthalmology Society (EUNOS) Advisory Committees, Review Groups/Study Sections 2010 – present OSA Member Advisory Network Group, Optical Society of America (OSA) 2011 Jean Bennett Memorial Travel Grant Program Selection Committee, Optical Society of America (OSA) 2011 Robert S. Hilbert Memorial Student Travel Grants Selection Committee, Optical Society of America (OSA) 2013 Invited Oral Board Examiner (Ophthalmic Optics) for King Saud University Ophthalmology Fellowship Oral Examination, held at King Abdulaziz University Hospital, Riyadh, Saudi Arabia Conference Organizer, Session Chair 2012 – present 2013 Technical Program Committee for Optical Society of America (OSA) Imaging Systems and Applications (IS) Topical Meeting, Imaging and Applied Optics: OSA Optics and Photonics Congress Session Co-Chair, “Medical II,” Optical Society of America (OSA) Imaging Systems and Applications (IS) Topical Meeting, Imaging and Applied Optics: OSA Optics and Photonics Congress, Arlington, Virginia Page 13 of 14 Curriculum Vitae – January 2014 Kristina Irsch, Ph.D. RECOGNITIONS Awards, Honors 2005 – 2006 2006 2009 2009 – 2010 2009 – 2010 2011 2012 Baden-Württemberg-STIPENDIUM. Scholarship of the Landesstiftung Baden-Württemberg for study and research abroad. Study Abroad Scholarship provided by the School of Medicine of the University of Heidelberg at Mannheim, Germany. Winner of the Medical category in the 2008 “Create the Future” Design Contest sponsored by National Aeronautics and Space Administration NASA Tech Briefs magazine and Dassault Systèmes SolidWorks Corporation. The Pediatric Ophthalmology and Strabismus Wilmer Research Grant Award Knights Templar Eye Foundation Young Investigator Award Biographical information included in the Marquis Who’s Who in America. Biographical information included in the Marquis Who’s Who in Medicine and Healthcare. Invited Talks March 2, 2010 Exploring the mechanisms of diplopia/cyclovertical strabismus with a tilting haploscope. Wilmer Five-o’clock Afternoon Research Meeting (FARM), Baltimore, Maryland. April 1, 2010 Untwisting screwed-up eyeballs – Quest to understand “congenital” superior oblique paresis. Wilmer Eye Institute Research Discussion (WEIRD) seminar, Baltimore, Maryland. March 19, 2012 Wave-plate-enhanced retinal birefringence scanning. Metropolitan Biophotonics Symposium 2012, Baltimore, Maryland. September 12, 2013 Detecting eye fixation and alignment using polarization properties of the retina, Laboratoire d'Etudes Spatiales et d'Instrumentations en Astrophysique (LESIA), Observatoire de Paris, Paris, France. September 23, 2013 Remote and calibration-free detection of eye fixation using polarization properties of the retina. University of Colorado Computational Optical Sensing and Imaging (COSI) Seminar Series, Boulder, Colorado. November 5, 2013 Visiting Professor. Detection of eye fixation and alignment using polarization properties of the retina. King Khaled Eye Specialist Hospital (KKESH) and King Saud University, Riyadh, Saudi Arabia. Page 14 of 14