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Transcript
CURRICULUM VITAE
Name:
Kristina Irsch, Ph.D.
DEMOGRAPHIC AND PERSONAL INFORMATION
Current Appointments
Assistant Professor of Ophthalmology
The Wilmer Eye Institute
The Johns Hopkins University School of Medicine
Baltimore, Maryland
Personal Data
Business address:
Phone:
E-mail:
Date of Birth:
Place of Birth:
Citizenship:
Wilmer 233
The Johns Hopkins Hospital
600 North Wolfe Street
Baltimore, Maryland 21287-9028
(443) 858-4255
[email protected]
April 24, 1982
Merzig (Saarland), Germany
German; U.S. Permanent Resident (“green card”) since May, 2012
EDUCATION AND TRAINING
2003
2005 – 2006
2006
2007
2007 – 2008
2008
Pre-diploma (“Vordiplom”) in Physics, University of Heidelberg,
Heidelberg, Germany.
Graduate research in Medical Physics (Biomedical Optics), The Wilmer
Eye Institute at The Johns Hopkins University School of Medicine,
Baltimore, Maryland.
Master of Science (M.S.) in Medical Physics with Distinction in
Radiotherapy and Biomedical Optics, University of Heidelberg and
University Hospital in Mannheim, Germany.
Diploma (“Diplom,” equivalent of Master’s degree) in Physics, University
of Heidelberg, Heidelberg, Germany.
Graduate research in Physics (Ophthalmic Optics), The Wilmer Eye
Institute at The Johns Hopkins University School of Medicine, Baltimore,
Maryland.
Ph.D. (“Dr. rer. nat.”) in Physics (Thesis advisor: Josef Bille, Ph.D.),
University of Heidelberg, Heidelberg, Germany.
Page 1 of 14
Curriculum Vitae – January 2014
2009 – 2010
Kristina Irsch, Ph.D.
Postdoctoral research fellowship in Ophthalmology – Ophthalmic
Instrumentation/Strabismus and Pediatric Ophthalmology (David L.
Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins
University School of Medicine, Baltimore, Maryland.
SPECIAL TRAINING
09/2005
09/2005
05/2009
07/2009
Workshop on Ophthalmic Optics, Moorfields Eye Hospital and the UCL
Institute of Ophthalmology, London, United Kingdom.
Workshop on Nuclear Medicine and Advanced Image Data Analysis,
Shanghai Jiao Tong University, Shanghai, China.
Photon Engineering’s Principles of Stray Light Short Course, Tucson,
Arizona.
Photon Engineering’s FRED Optical Engineering Software Tutorial,
Tucson, Arizona.
PROFESSIONAL EXPERIENCE
04/2004 – 09/2005
10/2007 – 12/2007
10/2008 – 12/2008
06/2010 – present
Assistant for Accelerator Operation (“Hilfsoperateur”), Max Planck
Institute for Nuclear Physics, Heidelberg, Germany.
Research Associate (“Wissenschaftlicher Mitarbeiter”) in the position of a
Teaching Assistant, School of Medicine of the University of Heidelberg at
Mannheim, Germany.
Research Associate (“Akademischer Mitarbeiter”) in the position of a
Teaching Assistant, School of Medicine of the University of Heidelberg at
Mannheim, Germany.
Assistant Professor of Ophthalmology, The Krieger Children’s Eye Center
at The Wilmer Eye Institute, The Johns Hopkins University School of
Medicine, Baltimore, Maryland.
RESEARCH ACTIVITIES
Publications: Peer-reviewed scientific articles
1. Agopov M, Gramatikov BI, Wu YK, Irsch K, Guyton DL. Use of retinal nerve fiber
layer birefringence as an addition to absorption in retinal scanning for biometric
purposes. Applied Optics 2008; 47(8): 1048-1053.
2. Ramey NA, Ying HS, Irsch K, Müllenbroich MC, Vaswani R, Guyton DL. A novel
haploscopic viewing apparatus with a three-axis eye tracker. Journal of the American
Association for Pediatric Ophthalmology and Strabismus 2008; 12(5): 498-503.
Page 2 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
3. Irsch K*, Ramey NA, Kurz A, Guyton DL, Ying HS. Video-based head movement
compensation for novel haploscopic eye tracking apparatus. Investigative Ophthalmology
& Visual Science 2009; 50(3): 1152-1157. *Corresponding author
4. Babar S, Khare GD, Vaswani RS, Irsch K, Mattheu JS, Walsh L, Guyton DL. Eye
dominance and the mechanisms of eye contact. Journal of the American Association for
Pediatric Ophthalmology and Strabismus 2010; 14(1): 52-57.
5. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Modeling and minimizing interference
from corneal birefringence in retinal birefringence scanning for foveal fixation detection.
Biomedical Optics Express 2011; 2(7): 1955-1968. *Corresponding author
6. Irsch K*, Shah AA. Birefringence of the central cornea in children assessed with
scanning laser polarimetry. Journal of Biomedical Optics 2012; 17(8): 086001.
*Corresponding author
7. Deng H, Irsch K*, Gutmark R, Phamonvaechavan P, Foo F, Anwar DS, Guyton DL.
Fusion can mask the relationships between fundus torsion, oblique muscle
overaction/underaction, and A- and V-pattern strabismus. Journal of the American
Association for Pediatric Ophthalmology and Strabismus 2013; 17(2): 177-183.
*Corresponding author
8. Irsch K*, Guyton DL, Ramey NA, Adyanthaya RS, Ying HS. Vertical vergence
adaptation produces an objective vertical deviation that changes with head tilt.
Investigative Ophthalmology & Visual Science 2013; 54(5): 3108-3114. *Corresponding
author
9. Gramatikov B, Irsch K, Müllenbroich M, Frindt N, Qu Y, Gutmark R, Wu K, Guyton D.
A device for continuous monitoring of true central fixation based on foveal birefringence.
Annals of Biomedical Engineering 2013; 41(9): 1968-1978.
10. Muthusamy B, Chang HP, Irsch K, Muthusamy K, Anwar DS, Ying HS, Guyton DL.
Differentiating bilateral superior oblique paresis from sensory extorsion. Journal of the
American Association for Pediatric Ophthalmology and Strabismus 2013; 17(5): 471476.
11. Muthusamy B, Irsch K, Chang HP, Guyton DL. The sensitivity of the Bielschowsky
head tilt test in diagnosing acquired bilateral superior oblique paresis. American Journal
of Ophthalmology 2014 Jan 9; doi: 10.1016/j.ajo.2014.01.003. [Epub ahead of print]
12. Adyanthaya RS, Broome S, Muthusamy B, Irsch K, Klein KS, Guyton DL. Down
syndrome and accommodation: The added advantage of bifocals. Journal of the
American Association for Pediatric Ophthalmology and Strabismus (in press).
Publications: Dissertation
Irsch K. Polarization modulation using wave plates to enhance foveal fixation detection
in retinal birefringence scanning for pediatric vision screening purposes. Dissertation
(Ph.D. thesis) 2009. University of Heidelberg. URL: http://www.ub.uniheidelberg.de/archiv/8938/
Page 3 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
Publications: Conference proceedings
1. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Spinning wave plate design for retinal
birefringence scanning. Proceedings of Society of Photo-Optical Instrumentation
Engineers SPIE 2009; 7169: 71691F1-12. *Corresponding author
2. Irsch K, Guyton DL, Li N, Ying HS. Cyclovertical fusion patterns after vertical vergence
adaptation in normals are different from those in some patients with superior oblique
paresis. Annals of the New York Academy of Sciences 2011; 1233: Supplementary file.
URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2011.06222.x/suppinfo
3. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. Wave-plate-enhanced retinal
birefringence scanning for true foveal fixation detection. Imaging and Applied Optics
Technical Papers, OSA Technical Digest (online) (Optical Society of America, 2012),
paper IM3C.4. *Corresponding author
4. Irsch K*, Guyton DL, Park HS, Ying HS. Different mechanisms of motor fusion may
differentiate between patients with true, versus masquerading, superior oblique paresis.
Transactions 34th European Strabismological Association (in press). *Corresponding
author
5. Irsch K*, Guyton DL, Ying HS. Objective analysis of the mechanism of vertical fusional
vergence to classify “congenital superior oblique paresis” and guide surgical approach.
Transactions 35th European Strabismological Association (in press). *Corresponding
author
6. Irsch K*, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener
employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus
detection and double-pass focus detection. Imaging and Applied Optics, J. Christou and
D. Miller, eds., OSA Technical Digest (online) (Optical Society of America, 2013), paper
ITh2D.5. *Corresponding author
Oral Presentations and Published Abstracts
1. Ying HS, Irsch K, Ramey NA, Zee DS, Guyton DL. Vertical vergence adaptation
decreases ocular counter roll gain. Neuroscience 2008 – The 38th annual meeting of the
Society for Neuroscience, November 2008, Washington, D.C.
2. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Optimized retinal birefringence scanning
using wave plates for strabismus screening. 20th Annual Wilmer Research Meeting, April
2009, Baltimore, Maryland.
3. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Polarization modulation using wave plates
to enhance foveal fixation detection in retinal birefringence scanning for strabismus
screening purposes. Association for Research in Vision and Ophthalmology (ARVO)
Annual Meeting, May 2009, Fort Lauderdale, Florida. Abstract published in Investigative
Ophthalmology & Visual Science 2009; 50: E-Abstract 4755.
4. Irsch K, Guyton DL, Roggia M, Ying HS. Can patients with superior oblique paresis
mimic the neural output of the ocular counter-roll mechanism to fuse vertically? 36th
American Association for Pediatric Ophthalmology and Strabismus (AAPOS) Annual
Page 4 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
Meeting, April 2010, Orlando, Florida. Abstract published in Journal of AAPOS 2010;
14(1): e4, 14.
5. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. How can patients
maintain binocular fusion in the presence of superior oblique paresis? XVIII International
Neuro-Ophthalmology Society (INOS) meeting, June 2010, Lyon, France. Abstract
published in Neuro-ophthalmology 2010; 34(3): VI-O 6, 206.
6. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may differentiate
between patients with true superior oblique paresis (SOP) and those with masquerading
SOP. 10th European Neuro-Ophthalmology Society (EUNOS) meeting, June 2011,
Barcelona, Spain. Abstract published in Neuro-ophthalmology 2011; 35(S1): S21.
7. Irsch K, Guyton DL, Park HS, Ying HS. Different fusional mechanisms may distinguish
patients with true superior oblique paresis (SOP) from those that masquerade as SOP.
34th European Strabismological Association (ESA) meeting, September 2011, Bruges,
Belgium.
8. Irsch K, Guyton DL, Ying HS. Classifying “congenital superior oblique paresis” using
an objective measure of vertical fusional vergence. XIX International NeuroOphthalmology Society (INOS) meeting, June 2012, Singapore. Abstract published in
Neuro-ophthalmology 2012; 36(S1): 7.
9. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Wave-plate-enhanced retinal
birefringence scanning for true foveal fixation detection. Optical Society of America
(OSA) Imaging Systems and Applications (IS) meeting, Imaging and Applied Optics:
OSA Optics and Photonics Congress, June 2012, Monterey, California.
10. Irsch K, Guyton DL, Ying HS. Objective analysis of the mechanism of vertical fusional
vergence to classify “congenital superior oblique paresis” and guide surgical approach.
35th European Strabismological Association (ESA) meeting, September 2012, Bucharest,
Romania.
11. Irsch K, Ying HS, Guyton DL. Fusion influences the Bielschowsky head tilt test in
superior oblique paresis. 39th North American Neuro-Ophthalmology Society (NANOS)
annual meeting, February 2013, Snowbird, Utah.
12. Irsch K, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener
employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus
detection and double-pass focus detection. Optical Society of America (OSA) Imaging
Systems and Applications (IS) meeting, Imaging and Applied Optics: OSA Optics and
Photonics Congress, June 2013, Arlington, Virginia.
13. Irsch K, Ying HS, Guyton DL. Lingering fusional adaptation influences the
Bielschowsky head tilt test in superior oblique paresis. 36th European Strabismological
Association (ESA) meeting, September 2013, Marseilles, France.
Poster Presentations and Published Abstracts
1. Ying HS, Ramey NA, Müllenbroich MC, Irsch K, Guyton DL. Basic cyclovertical
deviation and superior oblique palsy have similar head tilt behavior. American Academy
of Ophthalmology (AAO) Annual Meeting, November 2006, Las Vegas, Nevada, EAbstract P0624.
Page 5 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
2. Adyanthaya RS, Ying HS, Ramey NA, Müllenbroich MC, Irsch K, Guyton DL. A novel
haploscopic viewing apparatus with a three-axis eye tracker. Association for Research in
Vision and Ophthalmology (ARVO) Annual Meeting, May 2007, Fort Lauderdale,
Florida. Abstract published in Investigative Ophthalmology & Visual Science 2007; 48:
E-Abstract 897.
3. Ying HS, Irsch K, Vaswani R, Kurz A, Ramey NA, Adyanthaya RS, Zee DS, Guyton
DL. Ocular counter-roll is decreased after vertical vergence adaptation. Association for
Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2008, Fort
Lauderdale, Florida. Abstract published in Investigative Ophthalmology & Visual Science
2008; 49: E-Abstract 1802. Also presented at the XXV Bárány Society Meeting, April
2008, Kyoto, Japan.
4. Irsch K, Ying HS, Kurz A, Ramey NA, Adyanthaya RS, Guyton DL. Head movement
compensation for novel haploscopic eye tracking apparatus. Association for Research in
Vision and Ophthalmology (ARVO) Annual Meeting, May 2008, Fort Lauderdale,
Florida. Abstract published in Investigative Ophthalmology & Visual Science 2008; 49:
E-Abstract 1803.
5. Irsch K, Gramatikov BI, Wu YK, Guyton DL. Polarization modulation improves retinal
birefringence scanning. Optical Society of America (OSA) Vision Meeting, October
2008, Rochester, New York. Abstract published in Journal of Vision 2008; 8(17): 61,
61a, http://journalofvision.org/8/17/61/, doi:10.1167/8.17.61.
6. Ying HS, Irsch K, Ramey NA, Guyton DL. Vertical vergence adaptation produces a
transient cyclovertical deviation changing with head tilt. 35th American Association for
Pediatric Ophthalmology and Strabismus (AAPOS) Annual Meeting, April 2009, San
Francisco, California. Abstract published in Journal of AAPOS 2009; 13(1): e32, 127.
7. Ying HS, Irsch K, Ramey NA, Guyton DL. Vertical vergence adaptation produces an
incomitant transient cyclovertical deviation changing with gaze direction and head tilt.
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May
2009, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology &
Visual Science 2009; 50: E-Abstract 1990.
8. Ying HS, Irsch K, Guyton DL. Cyclovertical vergence in individuals with superior
oblique paresis is similar with attempted fusion or with head tilt. Neuroscience 2009 –
The 39th annual meeting of the Society for Neuroscience, October 2009, Chicago,
Illinois.
9. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. Can patients with
superior oblique paresis mimic the neural output of the ocular counter-roll mechanism to
fuse vertically? Association for Research in Vision and Ophthalmology (ARVO) Annual
Meeting, May 2010, Fort Lauderdale, Florida. Investigative Ophthalmology & Visual
Science 2010; 51: E-Abstract 2534.
10. Irsch K, Guyton DL, Roggia M, Phamonvaechavan P, Ying HS. Mechanisms of
binocular fusion in patients with superior oblique paresis. World Ophthalmology
Congress (WOC), June 2010, Berlin, Germany, Abstract P-SA-226.
11. Ying HS, Guyton DL, Li N, Irsch K. Subjects after adaptation to cyclovertical deviation
or with superior oblique paresis use opposite movements to fuse vertically. Basic and
Page 6 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
Clinical Ocular Motor and Vestibular Research meeting, March 2011, Buenos Aires,
Argentina.
12. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may distinguish
patients with true superior oblique paresis (SOP) from those that masquerade as SOP.
22th Annual Wilmer Research Meeting, April 2011, Baltimore, Maryland.
13. Doyle J, Purdy C, Tabibian D, Irsch K, Tarczy-Hornoch K, Braunstein K, Guyton DL.
Modified retinoscope to measure refractive error in Marfan syndrome mice. 22th Annual
Wilmer Research Meeting, April 2011, Baltimore, Maryland.
14. Irsch K, Guyton DL, Ying HS. Different mechanisms of motor fusion may distinguish
patients with true superior oblique paresis (SOP) from those with masquerading SOP.
Association for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May
2011, Fort Lauderdale, Florida. Abstract published in Investigative Ophthalmology &
Visual Science 2011; 52: E-Abstract 4698.
15. Gramatikov B, Irsch K, Guyton D. A monocular device for continuous monitoring of
central fixation using retinal birefringence scanning. Metropolitan Biophotonics
Symposium, March 2012, Baltimore, Maryland.
16. Ying HS, Geary RB, Irsch K. Visual and post-saccadic potentiation of ocular counter roll
gain results in near-stabilization of retinal images. Association for Research in Vision and
Ophthalmology (ARVO) Annual Meeting, May 2012, Fort Lauderdale, Florida. Abstract
published in Investigative Ophthalmology & Visual Science 2012; 53: E-Abstract 4871.
Also presented at Neuroscience 2012, October 2012, New Orleans, Louisiana.
17. Irsch K, Shah A. Central corneal birefringence in children assessed with scanning laser
polarimetry. Association for Research in Vision and Ophthalmology (ARVO) Annual
Meeting, May 2012, Fort Lauderdale, FL. Abstract published in Investigative
Ophthalmology & Visual Science 2012; 53: E-Abstract 3616. Also presented at the 23rd
Annual Wilmer Research Meeting, April 2012, Baltimore, Maryland.
18. Muthusamy B, Irsch K, Chang P, Guyton DL. The sensitivity of the Bielschowsky head
tilt test in diagnosing bilateral superior oblique paresis. 39th American Association for
Pediatric Ophthalmology and Strabismus (AAPOS) Annual Meeting, April 2013, Boston,
Massachusetts. Abstract published in Journal of AAPOS 2013; 17(1): e24, 85.
19. Irsch K, Ying HS, Guyton DL. The influence of fusion on the Bielschowsky head tilt test
in superior oblique paresis. 11th European Neuro-Ophthalmology Society (EUNOS)
meeting, April 2013, Oxford, United Kingdom. Abstract published in Neuroophthalmology 2013; 37(S1): 93-94.
20. Geary RB, Ying HS, Irsch K. Quick phase of the torsion vestibulo-ocular reflex
increases the gain of the slow phase both before and after the quick phase. Association
for Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle,
Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013;
54: E-Abstract 181.
21. Irsch K, Gramatikov BI, Wu YK, Guyton DL. A novel pediatric vision screener
employing wave-plate-enhanced, retinal-birefringence-scanning-based strabismus
detection and double-pass focus detection. Association for Research in Vision and
Page 7 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract
published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 3986.
22. Gramatikov BI, Irsch K, Guyton DL. Pupil size dynamics during the first minutes of
dark adaptation while fixating on a target. Association for Research in Vision and
Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract
published in Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 4374.
23. Deschler EK, Irsch K, Guyton KL, Guyton DL. Adjustable-suture strabismus surgery: A
new, removable, sliding noose. Association for Research in Vision and Ophthalmology
(ARVO) Annual Meeting, May 2013, Seattle, Washington. Abstract published in
Investigative Ophthalmology & Visual Science 2013; 54: E-Abstract 4711.
24. Muthusamy B, Adyanthaya R, Broome S, Irsch K, Klein K, Guyton DL. Down
syndrome and accommodation: The added advantage of bifocals. Association for
Research in Vision and Ophthalmology (ARVO) Annual Meeting, May 2013, Seattle,
Washington. Abstract published in Investigative Ophthalmology & Visual Science 2013;
54: E-Abstract 5684.
Inventions, Patents (pending, awarded)
1. Gramatikov BI, Guyton DL, Irsch K. Method and apparatus for detecting fixation of at
least one eye of a subject on a target. Invention disclosure (Ref. No. C11459) submitted
to the Johns Hopkins University Technology Transfer, 8 March 2011. U.S. Provisional
Patent Application (No. 61/450,996) filed in the U.S. Patent and Trademark Office, 9
March 2011. U.S. Patent Application (No. 13/416,979) filed in the U.S Patent Trademark
Office, 9 March 2012; published, 13 September 2012 (Pub. No.: US 2012/0229768 A1).
2. Gramatikov BI, Guyton DL, Irsch K. Eye fixation system and method. Invention
disclosure (Ref. No. C12166) submitted to the Johns Hopkins University Technology
Transfer, 13 September 2012. U.S. Patent Application (No. 13/773,307) filed in the U.S
Patent Trademark Office, 20 February 2013.
3. Ying HS†, Irsch K†, Guyton DL, Geary R, Gramatikov BI, Simons K. Method and
apparatus for detection of microstrabismus and stability of fixation in at least on eye to
screen for or diagnose amblyopia. Invention disclosure (Ref. No. C12286) submitted to
the Johns Hopkins University Technology Transfer, 21 December 2012. †Equal
contributions
4. Irsch K, Guyton DL, Gramatikov BI. Apparatus and method for minimizing the
influence of corneal birefringence on the analysis of eye fixation and focus using retinal
birefringence scanning. Invention disclosure (Ref. No. C12406) submitted to the Johns
Hopkins University Technology Transfer, 14 March 2013. U.S. Provisional Patent
Application (No. 61/793,350) filed in the U.S. Patent and Trademark Office, 15 March
2013. 5. Gramatikov BI, Guyton DL, Irsch K. Eye tracking and gaze fixation detection systems,
components and methods using polarized light. Invention disclosure (Ref. No. C12498)
submitted to the Johns Hopkins University Technology Transfer, 19 April 2013. U.S.
Provisional Patent Application (No. 61/823,738) filed in the U.S. Patent and Trademark
Office, 15 May 2013. Page 8 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
6. Gramatikov BI, Guyton DL, Toth CA, Izatt JA, Carrasco-Zevallos O, Irsch K. Method
and system for improving aiming during optical coherence tomography on young
children by synchronization with retinal birefringence scanning. Invention disclosure
(Ref. No. C12709) submitted to the Johns Hopkins University Technology Transfer, 16
September 2013. U.S. Provisional Patent Application (No. 61/885,794) filed in the U.S.
Patent and Trademark Office, 2 October 2013. Extramural Funding (current, pending, previous)
09/2008 – 11/2014
NIH R01 EY019347
Ocular Motor Adaptation in Health and Disease
Principal Investigator: Howard S. Ying, M.D., Ph.D.
Role: Co-Investigator
07/2009 – 06/2010
Knights Templar Eye Foundation Young Investigator Award
Optimized Retinal Birefringence Scanner for Strabismus Screening
Role: Principal Investigator
04/2010 – 03/2013
Hartwell Foundation Biomedical Research Award
Pediatric Vision Screening Instrument for Early Detection of Amblyopia
(‘Lazy Eye’)
Principal Investigator: Boris I. Gramatikov, Ph.D.
Role: Co-Investigator
06/2012 – 05/2013
RPB Walt and Lilly Disney Award for Amblyopia Research
Detection of Microstrabismus and Stability of Fixation in Amblyopia
Principal Investigator: Howard S. Ying, M.D., Ph.D.
Role: Co-Investigator
12/2012 – 11/2014
Hartwell Foundation Biomedical Research Collaboration Award
Diagnosis and Management of Infant Retinal Disease: Fast Swept Source
Optical Coherence Tomography Synchronized with Central Fixation
Principal Investigator: Cynthia A. Toth, M.D., Boris I. Gramatikov, Ph.D.
Role: Co-Investigator
EDUCATIONAL ACTIVITIES
Educational Publications: Letters, short reports
1. Deschler EK, Irsch K, Guyton KL, Guyton DL. A new, removable, sliding noose for
adjustable-suture strabismus surgery. Journal of the American Association for Pediatric
Ophthalmology and Strabismus 2013; 17(5): 524-527.
Educational Publications: Book chapters, monographs
1. Irsch K, Guyton DL. Anatomy of Eyes. In: Li SZ (Ed.): Encyclopedia of Biometrics.
Springer, New York, 2009; 11-16.
Page 9 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
2. Gutmark R, Irsch K, Guyton DL. Prescribing Prisms. Focal Points: Clinical Modules for
Ophthalmologists. American Academy of Ophthalmology, 2011; Vol. XXIX, No. 10
(Module 1 of 3).
3. Irsch K, Guyton DL. Anatomy of Eyes. In: Li SZ (Editor): Encyclopedia of Biometrics.
2nd ed. Springer, New York (in press).
Teaching: Classroom instruction
2007 – 2008
(annual)
Fall 2008
Basic Course in Physics and Optics for Medical Students, as part of the
Mannheim Reformed Curriculum for Medicine (MaReCuM) Program,
School of Medicine of the University of Heidelberg at Mannheim,
Germany.
Aberrometry and Wavefront Analysis course, as part of the International
Master’s Program in Medical Physics with Distinction in Radiotherapy
and Biomedical Optics, University of Heidelberg and University Hospital
in Mannheim, Germany.
Teaching: Laboratory instruction
2007 – 2008
(annual)
Fall 2008
Course in Optics and Microscopy for Medical Students, as part of the
Mannheim Reformed Curriculum for Medicine (MaReCuM) Program,
School of Medicine of the University of Heidelberg at Mannheim,
Germany.
Adaptive Optics Aberrometry and Wavefront Analysis and Confocal Laser
Scanning Ophthalmoscopy course, as part of the International Master’s
Program in Medical Physics with Distinction in Radiotherapy and
Biomedical Optics, University of Heidelberg and University Hospital in
Mannheim, Germany.
Teaching: Clinical instruction
2009 – present
(annual)
First-year ophthalmology resident class orientation: Retinoscopy and
subjective refraction practicum, The Wilmer Eye Institute, Baltimore,
Maryland.
Teaching: Didactic instruction
2012 – present
Resident lecture series: Ophthalmic Optics, The Wilmer Eye Institute,
(annual)
Baltimore, Maryland.
2012 – present
Houston Basic Science Course: Ophthalmic Optics, University of Texas,
(annual)
Houston, Texas.
March 11, 2013
The Osler Institute – Ophthalmology Review Course: Optics &
Refraction, Chicago, Illinois.
November 3-7, 2013 Basic Ophthalmology Course: Ophthalmic Optics, King Khaled Eye
Specialist Hospital (KKESH) and King Saud University, Riyadh, Saudi
Arabia.
Page 10 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
Teaching: CME instruction
August 6, 2009
Monocular Fixation Monitor Using Retinal Birefringence Scanning, the
Forerunner of the The Pediatric Vision Screener. Demonstration, with
Boris I. Gramatikov, Ph.D., National Association of Vision Professionals
(NAVP) 2009 Conference, Baltimore, Maryland.
August 6, 2009
The Pediatric Vision Screener. Demonstration, with Boris I. Gramatikov,
Ph.D. and David L. Guyton, M.D., National Association of Vision
Professionals (NAVP) 2009 Conference, Baltimore, Maryland.
December 9, 2010
Untwisting screwed-up eyeballs – Exploring superior oblique paresis with
a tilting haploscope. Lecture, Pediatric Ophthalmology Grand Rounds,
The Wilmer Eye Institute, Baltimore, Maryland.
Mentoring: Pre-doctoral
2006 – 2007
2007 – 2008
2008
2009, 2010
2011
Nicole Frindt. Graduate student in Medical Physics with Distinction in
Radiotherapy and Biomedical Optics, University of Heidelberg and
University Hospital in Mannheim, Germany. Received M.S. degree for
project (entitled “Alignment and testing of a retinal-birefringencescanning-based eye fixation monitor for attention deficit hyperactivity
disorder (ADHD) diagnosis and research”) conducted at The Wilmer Eye
Institute at The Johns Hopkins University School of Medicine, Baltimore,
Maryland.
Sonya Babar. Medical student, The Johns Hopkins University School of
Medicine, Baltimore, Maryland. Assisted in analysis of ocular counter-roll
gain after vertical vergence adaptation with novel haploscopic eye
tracking apparatus.
Yinhong Qu. Graduate student in Medical Physics with Distinction in
Radiotherapy and Biomedical Optics, University of Heidelberg and
University Hospital in Mannheim, Germany. Received M.S. degree for
project (entitled “Video-based target system for retinal-birefringencescanning-based eye fixation monitor for attention deficit hyperactivity
disorder (ADHD) screening and research”) conducted at The Wilmer Eye
Institute at The Johns Hopkins University School of Medicine, Baltimore,
Maryland.
Gilbert F. Xue. High school sophomore, River Hill High School,
Clarksville, Maryland. Assisted in validation of computer model
mathematically describing retinal birefringence scanning.
Ashesh A. Shah. Graduate student in Medical Physics with Distinction in
Radiotherapy and Biomedical Optics, University of Heidelberg and
University Hospital in Mannheim, Germany. Received M.S. degree for
project (entitled “Birefringence of the central cornea in children measured
using scanning laser polarimetry”) conducted at The Wilmer Eye Institute
Page 11 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
at The Johns Hopkins University School of Medicine, Baltimore,
Maryland).
Mentoring: Post-doctoral
2009
2009 – 2010
2010
2012
2013
Pittaya Phamonvaechavan, M.D. Post-doctoral research fellow in
Ophthalmology (David L. Guyton, M.D.), The Wilmer Eye Institute at
The Johns Hopkins University School of Medicine, Baltimore, Maryland.
Murilo Roggia, M.D. Post-doctoral research fellow in Ophthalmology
(Howard S. Ying, M.D., Ph.D.), The Wilmer Eye Institute at The Johns
Hopkins University School of Medicine, Baltimore, Maryland.
Ningdong Li, M.D. Post-doctoral research fellow in Ophthalmology
(Howard S. Ying, M.D., Ph.D.), The Wilmer Eye Institute at The Johns
Hopkins University School of Medicine, Baltimore, Maryland.
Emily K. Deschler, M.D. Post-doctoral clinical fellow in Ophthalmology
(David L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins
University School of Medicine, Baltimore, Maryland.
Brinda Muthusamy Post-doctoral clinical fellow in Ophthalmology (David
L. Guyton, M.D.), The Wilmer Eye Institute at The Johns Hopkins
University School of Medicine, Baltimore, Maryland.
ORGANIZATIONAL ACTIVITIES
Institutional Administrative Appointments
2011 – present
Wilmer Five-o’clock Afternoon Research Meeting (FARM)
Organizational Committee
Editorial Activities: Editorial board appointments
2011 – present
Medical Hypothesis, Discovery and Innovation (MEHDI) Ophthalmology
Journal
2012 – present
Ophthalmology and Eye Diseases
2013 – present
International Journal of Ophthalmology
Editorial Activities: Journal peer review activities
2010 – present
Clinical Optometry
2011 – present
Clinical Ophthalmology
2011 – present
Ophthalmology and Eye Diseases
2011 – present
Optics Letters
2012 – present
Applied Optics
2013 – present
Acta Ophthalmologica
Page 12 of 14
Curriculum Vitae – January 2014
2013 – present
2013 – present
Kristina Irsch, Ph.D.
Photonics Research
Journal of Biomedical Optics
Professional Societies
2002 – present
2005 – present
2006 – present
2007 – present
2007 – present
2009 – present
2009 – present
2009 – present
2011 – present
German Physical Society (“Deutsche Physikalische Gesellschaft,” DPG)
Association of Scholarship-Holders and Friends of the BadenWürttemberg-STIPENDIUM (“Verein der Stipendiaten und Freunde des
Baden-Württemberg-STIPENDIUMs”)
Association for Research in Vision and Ophthalmology (ARVO)
Optical Society of America (OSA)
Society of Photo-Optical Instrumentation Engineers (SPIE)
American Association for the Advancement of Science (AAAS)
German Society of Applied Optics (“Deutsche Gesellschaft für
angewandte Optik,” DGaO)
European Optical Society (EOS)
European Neuro-Ophthalmology Society (EUNOS)
Advisory Committees, Review Groups/Study Sections
2010 – present
OSA Member Advisory Network Group, Optical Society of
America (OSA)
2011
Jean Bennett Memorial Travel Grant Program Selection Committee,
Optical Society of America (OSA)
2011
Robert S. Hilbert Memorial Student Travel Grants Selection Committee,
Optical Society of America (OSA)
2013
Invited Oral Board Examiner (Ophthalmic Optics) for King Saud
University Ophthalmology Fellowship Oral Examination, held at King
Abdulaziz University Hospital, Riyadh, Saudi Arabia
Conference Organizer, Session Chair
2012 – present
2013
Technical Program Committee for Optical Society of America (OSA)
Imaging Systems and Applications (IS) Topical Meeting, Imaging and
Applied Optics: OSA Optics and Photonics Congress
Session Co-Chair, “Medical II,” Optical Society of America (OSA)
Imaging Systems and Applications (IS) Topical Meeting, Imaging and
Applied Optics: OSA Optics and Photonics Congress, Arlington, Virginia
Page 13 of 14
Curriculum Vitae – January 2014
Kristina Irsch, Ph.D.
RECOGNITIONS
Awards, Honors
2005 – 2006
2006
2009
2009 – 2010
2009 – 2010
2011
2012
Baden-Württemberg-STIPENDIUM. Scholarship of the Landesstiftung
Baden-Württemberg for study and research abroad.
Study Abroad Scholarship provided by the School of Medicine of the
University of Heidelberg at Mannheim, Germany.
Winner of the Medical category in the 2008 “Create the Future” Design
Contest sponsored by National Aeronautics and Space Administration
NASA Tech Briefs magazine and Dassault Systèmes SolidWorks
Corporation.
The Pediatric Ophthalmology and Strabismus Wilmer Research Grant
Award
Knights Templar Eye Foundation Young Investigator Award
Biographical information included in the Marquis Who’s Who in America.
Biographical information included in the Marquis Who’s Who in
Medicine and Healthcare.
Invited Talks
March 2, 2010
Exploring the mechanisms of diplopia/cyclovertical strabismus with a
tilting haploscope. Wilmer Five-o’clock Afternoon Research Meeting
(FARM), Baltimore, Maryland.
April 1, 2010
Untwisting screwed-up eyeballs – Quest to understand “congenital”
superior oblique paresis. Wilmer Eye Institute Research Discussion
(WEIRD) seminar, Baltimore, Maryland.
March 19, 2012
Wave-plate-enhanced retinal birefringence scanning. Metropolitan
Biophotonics Symposium 2012, Baltimore, Maryland.
September 12, 2013 Detecting eye fixation and alignment using polarization properties of the
retina, Laboratoire d'Etudes Spatiales et d'Instrumentations en
Astrophysique (LESIA), Observatoire de Paris, Paris, France.
September 23, 2013 Remote and calibration-free detection of eye fixation using polarization
properties of the retina. University of Colorado Computational Optical
Sensing and Imaging (COSI) Seminar Series, Boulder, Colorado.
November 5, 2013
Visiting Professor. Detection of eye fixation and alignment using
polarization properties of the retina. King Khaled Eye Specialist Hospital
(KKESH) and King Saud University, Riyadh, Saudi Arabia.
Page 14 of 14