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AP Biology
Animal Nutrition
What do animals need to live?
ƒ Animals make energy
using:
‹
‹
food
oxygen
food
ƒ Animals build bodies
using:
‹
food for raw materials
ƒ amino acids, sugars,
fats, nucleotides
‹
AP Biology
ATP
O2
ATP energy for synthesis
AP Biology
Nutritional requirements
ƒ Animals are heterotrophs
How do animals get their food?
need to take in food
‹ Why? fulfills 3 needs…
‹
ƒ fuel = chemical energy for production of ATP
ƒ raw materials = carbon source for synthesis
ƒ essential nutrients = animals cannot make
Š elements (N, P, K, Fe, Na, K, Ca...), NAD, FAD, etc.
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filter (suspension) feeding
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fluid feeding
substrate feeding
bulk feeding
1
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Different diets; different lives
ƒ All animals eat other organisms
‹
Herbivores
ƒ eat mainly plants
Š gorillas, cows,
rabbits, snails
‹
Carnivores
ƒ eat other animals
Š sharks, hawks, spiders, snakes
‹
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Omnivores
ƒ eat animals & plants
Š cockroaches, bears, raccoons, humans
Š humans evolved as hunters, scavengers & gatherers
Getting & Using Food
ƒ Ingest
‹
taking in food
ƒ Digest
‹
mechanical digestion
‹
chemical digestion
g
ƒ breaking up food into smaller pieces
ƒ breaking down food into molecules
intracellular
digestion
small enough to be absorbed into cells
ƒ enzymes (hydrolysis)
ƒ Absorb
‹
absorb across cell membrane
ƒ diffusion
ƒ active transport
ƒ Eliminate
‹
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AP Biology
undigested extracellular material
passes out of digestive system
extracellular
digestion
2
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Human digestive system
Alimentary Canal
Digestive systems
Everybody’s got one!
AP Biology
AP Biology
Common processes & structures
Swallowing (& not choking)
ƒ Movement & Control
‹
peristalsis
ƒ push food along by rhythmic waves of
smooth muscle contraction in walls of
digestive system
‹
sphincters
hi
ƒ muscular ring-like valves, regulate the
passage of material between sections of
digestive system
ƒ Accessory glands
‹
salivary glands, pancreas, liver & gall
bladder
ƒ secrete digestive juices (enzymes & fluid)
AP Biology
ƒ Epiglottis
‹
‹
‹
‹
problem: breathe & swallow through same orifice
flap of cartilage
closes trachea (windpipe) when swallowing
food travels down esophagus
ƒ Esophagus
‹
move food along to stomach by peristalsis
ƒ AP
Baby
Noodle
Biology
3
AP Biology
mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
Ingestion
ƒ Mouth
‹
mechanical digestion
ƒ teeth
Š breaking up food
‹
chemical digestion
ƒ saliva
Š amylase
„
enzyme digests starch
Š mucin
slippery protein (mucus)
protects soft lining of digestive system
„ lubricates food for easier swallowing
Š buffers
„ neutralizes acid to prevent tooth decay
Š anti-bacterial chemicals
„ kill bacteria that enter mouth with food
„
„
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Stomach
ƒ Functions
‹
food storage
‹
disinfect food
Ooooooh!
Zymogen!
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mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
stomach
ƒkills germs
ƒstore food
ƒbreak up food
ƒdigest proteins
ƒ can stretch to fit ~2L food
cardiac
sphincter
ƒ HCl = pH 2
Š kills bacteria
Š breaks apart cells
‹
chemical digestion
ƒ pepsin
Š enzyme breaks down proteins
Š secreted as pepsinogen
„
pyloric
sphincter
activated by HCl
But the stomach is made out of protein!
What stops the stomach from digesting itself?
mucus secreted by stomach cells protects
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stomach lining
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4
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Coevolution of parasite & host
Ulcers
Colonized by
H. pylori
ƒ Used to think
inflammation of
stomach
tried to control
with antacids
‹
‹
inflammation of
esophagus
Helicobacter pylori
H. pylori
inflammatory
proteins
(CagA)
Helicobacter pylori
now cure with
antibiotics
cytokines
cell damaging
proteins
(VacA)
helper T cells
neutrophil cells
Barry Marshall
white blood cells
AP Biology
AP Biology
Small intestine
ƒ Function
‹
major organ of digestion & absorption
chemical digestion
‹
absorption
abso
pt o tthrough
oug lining
g
‹
1982 | 2005
J. Robin Warren
ƒ Now
N
k
know ulcers
l
caused by
bacterial
infection of
stomach
Revolutionizing healthcare
"for their discovery of the bacterium Helicobacter pylori and its role
in gastritis and peptic ulcer disease"
ulcers were
caused by stress
‹
Free of
H. pylori
Duodenum
ƒ 1st section of small intestines
‹
ƒ digestive enzymes
acid food from stomach mixes with
digestive juices from accessory glands:
ƒ pancreas
ƒ liver
ƒ gall bladder
ƒ over 6 meters!
ƒ small intestine has huge surface area = 300m2 (~size
of tennis court)
ƒ Structure
‹
3 sections
ƒ duodenum = most digestion
ƒ jejunum = absorption of nutrients & water
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ƒ ileum = absorption of nutrients & water
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Pancreas
What stops
Ooooooh!
pancreas
Zymogen
!
from
digesting
ƒ Digestive enzymes
‹
itself
peptidases
ƒ trypsin
Š trypsinogen
ƒ chymotrypsin
Š chimotrypsinogen
yp
g
ƒ carboxypeptidase
Š procarboxypeptidase
‹
mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
small intestines
pancreas
ƒproduces enzymes to
digest proteins & starch
pancreatic amylase
ƒ Buffers
‹
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reduces acidity
ƒ alkaline solution rich in
bicarbonate (HCO3-)
ƒ buffers acidity of material from
stomach
Explain how this is a
molecular example of
structure-function theme.
Liver
ƒ Digestive System Functions
‹
stomach
ƒkills germs
ƒbreak up food
ƒdigest proteins
ƒstore food
produces bile
ƒ stored in gallbladder until needed
ƒ breaks up fats
Š act like detergents
g
to breakup
p fats
Circulatory System
Connection
bile contains
colors from old
red blood cells
collected in liver =
iron in RBC rusts &
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makes
feces brown
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mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
stomach
ƒkills germs
ƒbreak up food
ƒdigest proteins
ƒstore food
liver
ƒproduces bile
- stored in gall bladder
ƒbreak up fats
pancreas
ƒproduces enzymes to
digest proteins & starch
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6
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Digestive enzymes
Absorption by Small Intestines
ƒ Absorption through villi & microvilli
‹
finger-like projections
ƒ increase surface area for absorption
Ooooh…
Structure-Function
theme!
AP Biology
AP Biology
Absorption of Nutrients
ƒ Passive transport
‹
fructose
ƒ Active (protein pumps) transport
‹
pump
p
p amino acids, vitamins & glucose
g
ƒ against concentration gradients across
intestinal cell membranes
ƒ allows intestine to absorb much higher
proportion of nutrients in the intestine than
would be possible with passive diffusion
mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
liver
ƒproduces bile
- stored in gall bladder
ƒbreak up fats
pancreas
ƒproduces enzymes to
digest proteins & starch
stomach
ƒkills germs
ƒbreak up food
ƒdigest proteins
ƒstore food
small intestines
ƒbreakdown all foods
- proteins
- starch
- fats
- nucleic acids
ƒabsorb nutrients
Š worth the cost of ATP!
AP Biology
nutrients are valuable…
grab all you can get!
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7
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Large intestines (colon)
ƒ Function
‹
re-absorb water
ƒ use ~9 liters of water every
day in digestive juices
ƒ > 90% of water reabsorbed
Š not enough water absorbed
back to body
„ diarrhea
Š too much water absorbed back to body
„ constipation
You’ve got
company!
Flora of large intestines
ƒ Living in the large intestine is a rich
flora of harmless, helpful bacteria
‹
Escherichia coli (E. coli)
‹
bacteria produce vitamins
‹
generate gases
ƒ a favorite research organism
ƒ vitamin K; biotin, folic acid & other B vitamins
ƒ by-product of bacterial
metabolism
ƒ methane, hydrogen sulfide
AP Biology
AP Biology
Rectum
ƒ Last section of colon (large intestines)
‹
eliminate feces
ƒ undigested materials
Š extracellular waste
Tell them
about the
h rabbits,
„ mainly cellulose from plants
George!
„ roughage or fiber
ƒ salts
mouth
ƒbreak up food
ƒmoisten food
ƒdigest starch
ƒkill germs
liver
ƒproduces bile
- stored in gall bladder
ƒbreak up fats
pancreas
ƒproduces enzymes to
digest proteins & carbs
ƒ masses of
stomach
ƒkills germs
ƒbreak up food
ƒdigest proteins
ƒstore food
small intestines
ƒbreakdown food
- proteins
- starch
- fats
ƒabsorb nutrients
bacteria
appendix
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AP Biology
large intestines
absorb water
8
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Appendix
Hungry for Information?
Vestigial organ
Ask Questions!
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AP Biology
9