Download Data Sheet Flt3 Ligand Mouse Recombinant Catalogue Number IY

DataSheet
Flt3LigandMouseRecombinant
CatalogueNumber
IY-340
Fms-relatedtyrosinekinase3ligand,FLK2,STK1,CD135,StemCell
Synonyms
TyrosineKinase1,FLT3LG,Flt3.
FLT3ligandisareceptorfortheflcytokinehasatyrosine-proteinkinase
activity&agrowthfactorthatregulatesproliferationofearly
Introduction
hematopoieticcells.Flt3-LigandsynergizeswithotherCSFsand
interleukinstoinducegrowthanddifferentiation.
Thesaleand/orcommercialuseofRecombinantAdiponectinisprohibited
PatentRights
intheUnitedStatesofAmerica(U.S.A).
Flt3-LigandMouseRecombinantproducedinE.Coliisnon-glycosylated,
polypeptidechaincontaining163aminoacidsandhavingamolecular
Description
massof18587Dalton.Flt3-Ligandispurifiedbyproprietary
chromatographictechniques.
Source
EscherichiaColi.
PhysicalAppearence
SterileFilteredWhitelyophilized(freeze-dried)powder.
Formulation
TheFLT3LMouseproteinwaslyophilizedwithoutanyadditives.
ItisrecommendedtoreconstitutethelyophilizedFlt3-Ligandinsterile
Solubility
18MΩ-cmH2Onotlessthan100µg/ml,whichcanthenbefurtherdiluted
tootheraqueoussolutions.
LyophilizedFlt3-Ligandalthoughstableatroomtemperaturefor3weeks,
shouldbestoreddesiccatedbelow-18°C.UponreconstitutionFlt-3Ligand
shouldbestoredat4°Cbetween2-7daysandforfutureusebelow-18°C.
Stability
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%
HSAorBSA).
Pleasepreventfreeze-thawcycles.
Purity
Greaterthan98.0%asdeterminedbySDS-PAGE.
MTPDCYFSHSPISSNFKVKFRELTDHLLKDYPVTVAVNLQDEKHCKALWS
LFLAQRWIEQLKTVAGSKMQTLLEDVNTEIHFVTSCTFQPLPECLRFVQT
Aminoacidsequence
NISHLLKDTCTQLLALKPCIGKACQNFSRCLEVQCQPDSSTLLPPRSPIA
LEATELPEPRPRQ.
TheED50,calculatedbythedose-dependentproliferationofmouseAML5
BiologicalActivity
cellsis1.3-2.0ng/ml.
ProductsarefurnishedforLABORATORYRESEARCHUSEONLY.The
Usage
productmaynotbeusedasdrugs,agriculturalorpesticidalproducts,food
additivesorhouseholdchemicals.