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Caring for Persons with Diabetes Developed by: American Optometric Association Health Promotions Committee Epidemiology of Diabetes 26 million Americans have diabetes – 90% have type 2 diabetes 79 million more Americans are at high risk for developing diabetes within ten years 1.8 million new cases diagnosed each year Diabetes care accounts for 1 of every 6 health care dollars spent in the US Epidemiology of Diabetes The incidence of Type 2 diabetes in Americans < 20 years of age has grown 1100% since 1970 It is the fastest growing sub-population of diabetes by far Diabetes is the 6th leading cause of death in the US The leading cause of blindness in those < 74 yo The leading cause of kidney failure The leading cause of non-traumatic amputation Diabetes Myths Diabetes is caused by eating too much sugar Not taking medications to control diabetes means the disease is less serious Having type 2 diabetes is ‘better’ than having type 1 diabetes Type 2 diabetes is not hereditary A Look at the Numbers… Diabetes Affects 28.5 Million Americans Of those: – 18.8 million diagnosed – 7 million not yet diagnosed – 215,000 are under 20 and mostly have type I diabetes Diabetes is… The LEADING cause of – Kidney failure – Non-traumatic lower limb amputations – New cases of blindness in adults A MAJOR cause of – Heart disease – Stroke The 7th leading cause of death in USA Diabetes: A Definition Failure of the pancreas to produce sufficient amounts of the hormone insulin - or Resistance of the body’s cells to the action of insulin Insulin Insulin allows cells throughout the body to absorb sugar (glucose) from the bloodstream The source of glucose is mostly from carbohydrates in the foods we eat, but it can also be made by breaking down glucose stored in our muscles and liver Insulin & Glucose are necessary for the brain, heart & kidneys to function When Insulin isn’t Helping Glucose into the Cells… Hyperglycemia occurs (blood sugar levels go up) This causes damage to body tissues, especially blood vessels This then leads to eye disease, kidney disease, nerve disease and heart disease Diabetes-related eye disease predicts these other diseases Diabetes Mellitus - Classification Insulin Dependent (IDDM) Non-Insulin Dependent (NIDDM) Gestational (GDM) Insulin-Dependent Diabetes Mellitus (IDDM) Results from destruction of islet cells in the pancreas More common in persons under 20 years of age Etiology both genetic and environmental Patients acutely symptomatic at the time of onset (“the polys”) Non-Insulin Dependent Diabetes Mellitus (NIDDM) Resistance of body tissues to the action of insulin: – Insulin resistance – Beta-cell failure Usually occurs after age 40 Gradual onset of symptoms (half are unaware) Occurring more frequently in children Risk factors: – Overweight & sedentary – Family history of diabetes – Ethnic origin Gestational Diabetes Mellitus (GDM) Glucose intolerance of variable severity with onset or first recognition during pregnancy (2nd & 3rd trimester) Complicates between 1% and 4% of pregnancies Limited to the term of the pregnancy Fetal outcome - Macrosomia GDM Moms are 50% more likely to develop NIDDM later Offspring are more likely to develop NIDDM during their lifetime What Are the Symptoms? All type 1 patients have symptoms Many type 2 patients have few or no symptoms until serious complications develop (e.g. a heart attack) Symptoms of Hypoglycemia Shaking Sweating Fast heart beat Dizziness Anxious Hunger Impaired vision Weakness Fatigue Head Ache Irritable Symptoms of severe low blood sugar Seizure Loss of consciousness (coma) Stroke Death Treatment of Hypoglycemia 15 to 20 grams of carbohydrate that puts glucose into your bloodstream in about 5 minute will raise your blood sugar about 30 milligrams per deciliter (mg/dL) in about 15 to 20 minutes Check your blood sugar level again 15 minutes Have person drink ½ glass of juice or regular soft drink,or 1 glass of milk If symptoms don’t stop, call internist Then eat a light snack (1/2 peanut butter or meat sandwich and ½ glass of milk) Always have a rapid-acting carbohydrate in the office Symptoms of Hyperglycemia Extreme thirst Frequent urination Dry skin Healing difficulties Hunger Drowsiness Blurred vision Treatment of Hyperglycemia Have patient test blood sugar You can often lower your blood glucose level by exercising. However, if your blood glucose is above 240 mg/dl, check your urine for ketones. If you have ketones, do not exercise Exercising when ketones are present may make your blood glucose level go even higher. Drink more water Change medication/ eating habits If >200mg/dl for several tests, for two days, or if extremely elevated: Call internist Treatment Modes Pen injectors Inhaled Insulin (currently off the market) Insulin pumps CGMs Net based education New medications Insulin used more than in past Non-Retinal Eye Complications CORNEA - One of two clear tissues in the body LENS - The other clear tissue – It is a very complex process to keep these tissues clear Refractive error In poorly controlled diabetes very high levels of glucose can cause the lens metabolism to shunt down a sorbital pathway Sorbital buildup in the lens creates an osmotic swelling of the lens with resulting in refractive changes Poor Pupil Response Before Dilating Drops 30 minutes After Dilating Drops Non-Retinal Eye Complications IRIS - Colored part of eye - rubeosis irides - new vessel growth that can cause serious glaucoma complications and is usually associated with PDR – Typically is associated with advanced diabetic retinopathy; not easy to identify GLAUCOMA - Twice as likely in persons with diabetes and more likely to cause vision loss Non-Retinal Eye Complications OPTIC NERVE - Can sometimes swell (optic neuritis) generally found in younger persons with diabetes and can lead to permanent vision loss CRANIAL NEUROPATHIES - Ptosis (lid droop) and proptosis (eye bulge); occasional reversible diplopia; Bell’s Palsy Eyelids - Skin related problems Eye Muscle Problems Retinal Eye Complications BDR - Background Diabetic Retinopathy – Microaneurysms, leakage of intravascular fluid, intraretinal hemorrhage, retinal ischemia PPDR - Pre Proliferative Diabetic Retinopathy PDR - Proliferative Retinopathy – New Vessel Growth Remember – the retina is a very thin tissue Mild NPDR Standard Photo 1 Moderate NPDR Standard Photo 2A Severe NPDR Standard Photo 2B Very Severe NPDR Standard Photo 5 Proliferative Diabetic Retinopathy (PDR) Neovascularization of the Disc (NVD) Neovascularization Elsewhere (NVE) Pre-retinal Hemorrhage (PRH) Vitreous Hemorrhage (VH) Non-High Risk Proliferative Diabetic Retinopathy Standard Photo 10A Standard Photo 6B High Risk Proliferative Diabetic Retinopathy Standard Photo 10C Standard Photo 7 Standard Photo 10 Standard photo 13 Laser Photocoagulation Treatment Injections Triamcinolone acetonide Lucentis and Avastin Diabetic Macular Edema (DME) The collection of intraretinal fluid in the macular area Disrupts retinal structure With or without lipid exudate or cystoid changes Focal or diffuse Can occur at any stage of retinopathy Only treated when it becomes “clinically significant” Follow-up every 3 to 4 months by a retinal specialist Clinically Significant Macular Edema (CSME) Patients referred for treatment immediately. CSME responsible for nearly HALF of all vision loss in diabetes! Diabetic Retinopathy The most significant ocular complication of diabetes The leading cause of blindness - ages 20-74 All complications of diabetes have a slow progression in the beginning – leads to patient non-compliance Type I Diabetes Past thinking: Usually free of retinopathy for first ten years after diagnosis Present Thinking: 20% have retinopathy at one year; 67% have retinopathy at five years 95% have retinopathy after 15 years or more Type II Diabetes May have retinopathy at diagnosis 30% have retinopathy within 5 years 80% have retinopathy within 15 years Severity of Diabetic Retinopathy Depends on – Disease Duration - always ask how long – High Blood Pressure - very serious – High Glycosolated Hemoglobin – Smoking = major risk Example: – Patient A.J. (HTN, A1c = 10, smoker): diabetes less than 20 years; vision: 20/800 – Patient D.D. (good control of all risk factors): diabetes greater than 25 years, vision: 20/15 Optometric Management of Persons with Diabetes Frequency of Exams – After Diagnosis: Every Year Dilated Pupil Exam (Should be pre-scheduled) – After First Diagnosis of Diabetic Eye Changes: Every year or six months – At Pre-Proliferative Stage Should be referred to retinal specialist Less than 50% of persons with diabetes get dilated eye exams yearly – You must preschedule!! Treatment Options PREVENTION - 75% of all diabetic retinopathy could be eliminated with proper control of the disease – Medication - Drs. do adequate job – Exercise - Drs. do poor job – Diet - Drs. do poor job One of the greatest causes of death and disability in the USA is overeating and a diet heavy in fats, meats, and sugars Treatment Options Argon Laser Photocoagulation Pan Retinal Photocoagulation – Laser kills peripheral retinal tissue – feedback to brain says - “this is dead tissue, no need to grow vessels here” Victrectomy – Remove bloody scarred vitreous and replace with saline – Injections Laser Photocoagulation Reduces visual loss by 50% Goals: – Prevent further neovascularization – Reduce risk of vitreous hemorrhage and/or reduce traction retinal detachment Side Effects (lessened now with injections) – Constriction of peripheral vision – Decreased night vision – Loss of acuity Treatment Options Early Diagnosis is the Key – ALWAYS preschedule your patients with diabetes for annual (and other) visits Education/Motivation is Essential – 1-800-DIABETES/diabetes.org – Diet Consult – Exercise Consult – Diabetes Education Classes now covered by major medical and Medicare Why Does Diabetes Kill So Many Americans? Doctors do not seem to understand the disease Patients do not seem to understand the disease The public does not seem to understand the disease Not many people care – primarily affects older people, or under/un-insured Obesity by the numbers Complications from obesity kill more Americans than smoking – and smoking kills 1000 Americans per day!!!! Strokes, hypertension, cardiovascular disease, and diabetes can all cause blindness, as well as other disabilities and death Supersized Suicide The food industry produces 3800 calories per day for every person in the USA; up from 3300 from the 70s. Adult females need 2200; adult males 2500 The food industry spends 10 billion dollars yearly in direct advertising and another 20 billion in indirect advertising (school scoreboards etc.) Two words: Free Refills!! (and what ever happened to a ten ounce bottle of soda?) Supersized Suicide The campaign for fruits and vegetables spends about 2 million per year on public education The food industry pushes processed foods (potatoes are cheap; potato chips are not) Portion sizes have increased dramatically Kids in the line of fire 70% of obese children will become obese adults Most breakfast cereals and kid drinks should be labeled as candy – Froot Loops has no fruit and no fiber Soda Pop parties; food as a reward; candy and bake sale fundraisers; terrible cafeteria food; less exercise, more video games, and more computer time A paradigm shift needs to occur Insurance will pay for special shoes, medical procedures (such as amputation), however, dietary counseling needs to be covered as well. Nutrition training is important for doctors, additionally it is important to discuss weight even when the patient’s ‘vital signs’ seem OK Obesity is not a cosmetic issue, it is a medical issue Research on obesity is obscene NIH = 226 million for obesity research NIH = 2 billion for cardiovascular research If we cured the obesity, we wouldn’t have near the cardiovascular disease! Are we just overeating? We are exercising less Our jobs require less manual labor We have larger portions shoved at us We have advertising bombarding us We are eating out more For easing stress, if we don’t do drugs, we do food Even as adults, food is a reward Is this just a USA thing? Well, no, but look at this………. Great Marketing Tricks Millions of dollars are spent encouraging us to eat more highly processed foods What can WE do?? Share portions Special order Take home boxes or just leave it on the plate Don’t be blinded by the advertising Eat less processed foods Reduce meats, fats, and high sugar foods Forget about special ‘no protein, all protein, no white food, blah, blah, blah diets and simply change your eating behavior Exercise more Self Monitoring of Blood Glucose One Touch Ping and Animas Pump SMBG Self-monitoring of blood glucose All patients should perform SMBG – Fasting and after meals (ideally, but rarely done, and if so usually on Type I persons) – 50% of people with diabetes do NO SMBG Normal blood glucose is between 70-110 – Up to 150 after a meal – Less than 90 in the morning after fasting Continuous Glucose Monitors Inserted under the skin Replaced generally weekly Shows trends Still must be calibrated with finger sticks twice daily Alarm settings can signal a call to action Some will “talk” to an insulin pump but not make automatic changes Dexcom Continuous Monitor Transmitter and receiver What Does Diabetes Research Tell Us? Keeping blood pressure levels below 130/80 lowers the risk of all diabetes complications Getting an annual dilated eye exam cuts the risk of going blind from diabetes by up to 95% by allowing for early detection of eye complications Hemoglobin A1c (HbA1c) HbA1c measures the AVERAGE blood sugar level over the preceding 3 months HbA1c predicts those people most likely to go blind and/or die from diabetes “Normal” HbA1c is around 5% The average patient with diabetes has an HbA1c of 8.5% For most people with diabetes, the HbA1c goal is <6.5% – Exceptions are kids and those with established CVD What Does Diabetes Research Tell Us? Keeping blood sugar levels as close to normal as possible lowers the risk of all diabetes complications – Diet (especially portion control) – Exercise (lowers blood sugar & improves insulin resistance) – Medication Patients & Doctors need to know their numbers and what they mean… Preventing Diabetes Walking 30 minutes each day, five days each week, reduces the risk of developing diabetes by up to 60% Sleeping 7-8 hours and eating more vegetables also lowers diabetes risk If you don’t get diabetes, you can’t go blind, lose a foot, or die from diabetes! Who Should Educate? Each and every health care provider, including para-optomteric staff The best way to change unhealthy behaviors is by building a relationship with your patient If the patient hears the same plan from every provider, they are more likely to follow through on proper care Practical Tips for Health Care Team Tell the doctor you’re interested in helping provide excellent diabetes care Learn all you can about diabetes Make sure you’ve got orange juice or sugared soda set aside for patients Develop a plan to measure blood pressure & ask about HbA1c for every patient with diabetes Practical Tips for Health Care Team Ask about SMBG Ask about physical activity Ask about common diabetes medicines – Insulin and/or pills for blood sugar – Blood pressure & cholesterol medicines – Aspirin therapy Practical Tips for Health Care Team Ask who treats their diabetes & how often they’re seen Ask if they would like more information on diabetes and preventing complications Help the doctor to make sure that every patient with diabetes is dilated annually Remember that diabetes is not who they are, but a condition they have What the DCCT Told Us Prevention IS the cure – 76% less retinopathy – 54% less kidney disease – 60% less neuropathy – 50% less amputations These results are over ten years old and doctors and patients still do not understand Key Points Diabetes is a serious disease Diabetes has become an epidemic Treating diabetes complications like eye disease and heart disease is a LOT more expensive than preventing those complications Eye doctors and their assistants are on the ‘front line’ in the battle against diabetes, and can make a real difference Optometric Role in Managing Patients with Diabetes Take a good case history to find the undiagnosed (6 million) – Episodes of blurred vision? – Polys – Increased thirst, hunger, urination, – FFFF – Fat, Forty, Female, Family History Low Vision Training – provide low vision care for the partially sighted Pre-schedule all persons with diabetes Refer to diabetes specialists – Internists – Dieticians – Diabetes educators Low vision exams Low Vision exams -evaluate functional vision and -assesses individual needs (especially important for those with vision loss due to diabetes) LCD video magnification Sharper image than TV Up to 50X magnification Takes up less space Around 2200.00 Enables patient to read or look at pictures And write checks and letters Lighted magnifiers reduce glare and provide contrast Spectacle mounted telescopes can improve distance vision dramatically State Department of Rehabilitation Can Give a Workshop on Services They Provide Can Be A Great Referral Service for Low Vision Patients Summary: Very Serious Disease Early Detection Essential Education Essential Good Control = Less Complications Intervention/Treatments = Less Blindness Low Vision Services May Help to Rehabilitate Patients Who Have Lost Vision THANK YOU! For More Info: American Optometric Association: aoa.org American Diabetes Association: diabetes.org National Institutes of Health: ndep.nih.gov