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BI 251 - Fall Study guide and potential essay questions for Chapter 10 – Muscle tissue • Same instructions/information as those printed in this space on the Chapter 1 Study Guide. Skeletal Muscle Terms A band, acetylcholine (ACh), acetylcholinesterase (AChE), all-or-none principle, calsequestrin, concentric contraction, cross-bridges, eccentric contraction, endomysium, epimysium, excitation-contraction coupling, F actin, G actin, H zone, I band, isometric contraction, isotonic contraction, latent period, M line, metabolic acidosis, motor end plate, motor unit, motor unit, muscle tone, myofiber, myofibril, myofilament, myomesin, myosin, myosin-binding site, neuromuscular junction, perimysium, recruitment, phosphagen system, rigor mortis, sarcolemma, sarcomere, sarcoplasm, sarcoplasmic reticulum (SR), satellite cell, series elastic component, thin and thick filaments, titin, transverse tubule (T-tubule), treppe (warm up effect), tetany, tropomyosin, troponin, wave summation, Z band, zone of overlap Skeletal Muscle Tissue 1. List the events that lead to the contraction of a muscle cell. Include all information contained in the three lecture note slides that are cleverly titled, “Events Leading to Contraction.” 2. “Resting” muscles cells are, by definition, not contracting, but they are prepared to do so. List the physiologically relevant conditions that exist in a resting muscle cell. 3. What is the function of acetylcholinesterase (AChE)? 4. Perry Mason has some questions for you: What is rigor mortis? Specifically, why does rigor mortis appear after death? What causes it to disappear? 5. Define the term “excess postexercise oxygen consumption” (EPOC)? What factors are thought to cause EPOC? 6. Define the term “latent period” as it relates to muscle physiology. 7. What factors contribute to muscle fatigue? 8. Compare and contrast Slow Oxidative (Slow) and Fast Glycolytic (Fast) muscle fiber types with respect to: • ATP hydrolysis rate, ATP production (aerobic vs. anaerobic), capillary supply (density), color, contraction speed, fatigue resistance, fiber cross-sectional diameter, glycogen content, mitochondrial density, myoglobin content, recruitment order, and substrates for ATP production. • A table or list could constitute a very good answer to this question. However, a clear comparison of the two types must be evident. • Please remember that these characteristics are interrelated – do not memorize a bunch of unrelated facts! The names of the fiber types were chosen to indicate the characteristics of the fiber types. BI 251 - Fall • See lecture notes. Use Table 10-3, p. 309 in the text for clarification, if necessary, but I specifically want you to use the table in the lecture notes to answer this question if it is on the exam. I have a reason for this; ask me and I’ll tell you what my reason is. 9. What factors influence the maximum force that a muscle fiber is able to generate? What factors influence the maximum force that a whole muscle is able to generate? 10. Explain how the length of a muscle fiber at the time that it is stimulated to contract affects the tension (force) that it is able to generate during contraction. (A properly labeled graph could be a good answer.) 11. List five functions of skeletal muscle. 12. List four (4) general ways in which drugs or toxins might excite or inhibit muscle contraction. 13. Define the term “all-or-none principle” as it relates to the contraction of a muscle fiber. 14. Be certain that you understand the ways in which muscle cells produce ATP for contraction during rest, moderate activity and peak exercise. (Figure 10-20) Checkpoint Questions Page 308 9. How would a drug that blocks acetylcholine release affect skeletal muscle contraction? 11. Predict what would happen to a muscle if the motor end plate failed to produce acetylcholinesterase. Explain. Page 316 12. Why does a muscle that has been overstretched produce less tension? Page 324 19. Which activity would be more likely to create an “oxygen debt”: swimming laps or lifting weights? Explain your answer. Page 328 24. Which type of muscle tissue is least affected by changes in extracellular Ca2+ concentration during contraction? Smooth Muscle Terms calmodulin, dense bodies, gap junction, intermediate filaments (desmin), multi-unit smooth muscle, myosin light chain kinase, pacemaker cells, single-unit (visceral) smooth muscle Smooth Muscle Potential Short-answer Question 1. List the steps involved in the contraction of smooth muscle fiber.