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1 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols NURSE PRACTITIONER CLINICAL PROTOCOL MANAGEMENT OF AGGRESSION AND AGITATION For Mental Health Consultation – Liaison Services Prepared by: Mary-Ellen Dodds, RN, RMHN, BSc (Nsing), MN (Nse Pract), MACMHN. April 2011 Revised Version Sir Charles Gairdner Hospital North Metropolitan Health Service Acknowledgements: Mack Madahar- NP-Intern, Curtin University of Technology, Bentley, WA- for his updated clinical research and input Greater Western Area Health Service (2006). Clinical Guidelines: Nurse Practitioner Mental Health Baradine. Royal Prince Alfred Hospital. Central Sydney Area Mental Health Service. (2004). Nurse Practitioner Guidelines: Role and Scope of Practice. Western Sydney Area Mental Health Service. Auburn and Westmead Hospitals. (2004). Clinical Practice Guidelines: Nurse Practitioner Mental Health. Issued: 2007 Reviewed: 2011 Next Review: 2014 2 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols STATEMENT OF INTENT OF THESE CLINICAL PROTOCOLS AND DISCLAIMER The information provided in these Clinical Protocols is intended for information purposes only. Clinical Protocols are designed to improve the quality of health care and decrease the use of unnecessary or harmful interventions. These Clinical Protocols have been developed by clinicians and researchers for use within Sir Charles Gairdner Hospital. They provide advice regarding the care and management of patients presenting with mental illnesses or mental health issues by the Nurse Practitioner – Mental Health. While every reasonable effort has been made to ensure the accuracy of these Clinical Protocols, no guarantee can be given that the information is free from error or admission. The recommendations do not indicate an exclusive course of action or serve as a definitive mode of patient care. Variations which takes into account individual circumstances, clinical judgement and patient choice may also be appropriate. Users are strongly recommended to confirm by way of independent sources that the information contained within the Clinical Protocol is correct. The information contained in these Clinical Protocols is NOT a substitute for clinical judgement whereby appropriate diagnosis, treatment and advice are taken into account. These Clinical Protocols may also include references to the quality of evidence used in their formulation. Where this has not been located, the Clinical Protocols include references to support the recommended care. Providing a reference does not constitute an endorsement or approval of that source or any information, products or services through that source. The Minister for Health, the State of Western Australia, and their Employees and Agents will accept no liability for any act or omission occurring as a consequence of relying on these Protocols in clinical use or as a result of the use of these Protocols Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 3 TABLE OF CONTENTS Disclaimer 5 * * * * 4 4 4 5 Disease Aetiology Patient Population Patient Contacts Expected Outcomes of Protocols Clinical Protocol Aggression / Agitation 6-15 Discharge / Referral Criteria 16 Best Practice Evidence 16 Review 17 Implementation Plan 17 Evaluation Plan 17 Formulary 19 References 20 4 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols Disease Aetiology Although the exact cause of most mental illnesses is not known it is progressively becoming more evident that many mental illnesses are caused by a combination of genetic, biological, psychological and environmental factors. Some mental illnesses are known to run in families, which suggests that the illness may be passed on from parents to child through genes making such children more susceptible to developing the illness. Experts believe that genetic causes of mental illness occur due to defects in multiple genes – not just a single gene as with other disorders. Individuals with defective genes when exposed to other factors such as environmental stressors are more likely to develop the disorder. Some mental illnesses are closely linked to biological causes such as an abnormal balance of neuro-transmitter chemicals in the brain. These chemicals are responsible normal functioning in the brain and if not working properly, normal communication between nerve cells in the brain may severely impaired. In addition, injuries to certain parts of the brain are linked to the development of mental illness. Psychological trauma especially in childhood has also been shown to be linked to the development of mental illness in adulthood. In addition, stressors such as death and divorce and substance abuse can trigger mental illness in a person who may be at risk for developing mental illness (MedicineNet, 2005; Askey, 2002; Brockington, 2004; Marmot, 2005; Davies, 1997) Patient Population: The population of patients to whom these protocols pertain to will include all patients admitted to the general wards at Sir Charles Gairdner Hospital for medical reasons that have a mental illness or mental health issue associated with their medical condition. This includes patients who have behaviours, which render their management difficult either for themselves or for those health professionals caring for them. Patient Contacts: Since its inception in 2001-2002, requests for mental health review of patients believed to be suffering from mental illnesses or mental health issues have been at a steady rise. Patient contacts have risen from 165 patient contacts in 2001 to 949 patient contact in 2010. Addendum 1 illustrates the incremental growth of patient contacts in a tabled form. The author believes that the total current levels of patient service have reached its capacity for 1 full-time equivalent staff. If more patients are to be referred to the service, will require additional resources in the form of staff and office space. Such patients are referred directly to the Clinical Nurse Consultant (Psychiatry) by both medical and nursing staff for primarily mental health assessment and then ongoing management of the patient’s mental health problem. Treatments provided cover a wide range of management options including counselling, relaxation training and behavioural therapy. In addition, due to the difficulty in managing some of these patients due to abnormal behaviour, support and education is provided to staff. Currently, if the patient is considered to require either medication or referral to another health professional, the treating team must make referrals on the 5 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols recommendation of the Clinical Nurse Consultant (Psychiatry). Thus if the treating team does not believe that the patient’s mental health problem is a priority the patient does not receive or the appropriate mental health care is delayed significantly. The ability to directly refer patients and commence appropriate mental health treatment would be greatly enhanced by the designation of a Mental Health Nurse Practitioner. Expected Outcome of the Protocols: Early intervention in mental illnesses is believed to be best practice in management. It is suggested that early access to mental health care will reduce the loss of function and disability which often results as a consequence of serious mental illness. 6 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols CLINICAL PROTOCOL : THE MANAGEMENT OF AGGRESSION AND AGITATION Perhaps the most problematic behaviour in the management of patients with a mental illness and /or mental health issues is the potential for agitation and aggression and in some cases the enactment of these behaviours. Underlying mental illness and personality traits often make it difficult to deal with the cumulative stresses of hospitalisation resulting in episodes of aggression. Currently, instances of aggression rely heavily on medical staff to prescribe appropriate medication to primarily manage the patient escalating anxiety and arousal and secondly, to sedate patients in the event that their behaviour escalating to physical violence. This can be problematic both for the patient and the health professional. Sullivan (1998) has suggested that mental health nurses confront potentially hostile and aggressive patients on a regular basis however, recent developments on this topic suggests that the issue of workplace aggression and violence are now part of the broader discussion (Beech & Bowyer, 2004). Aggression can be verbal and/ or physical and is most likely in the acute phase of psychosis especially if the patient is experiencing auditory hallucinations or paranoid delusions. Anger may also be a response to environmental factors but combined with personality traits and the emotional stresses associated with hospitalisation, the expression of these feelings may be exaggerated or distorted (Orygen Research Centre, 2004; Hill, 2000; McGeorge & Landow, 2000). A contributing factor to aggression is often agitation which is a degree of psychological and motor hyperactivity. It is symptomatic of the patient’s underlying psychological and/or physical disturbance and is often seen in acutely psychotic and dementing patients. It is a major contributing factor to aggression. The need to manage these behaviours is imperative if we are to achieve a positive hospital experience for the patient. Most patients will become anxious and upset when faced with threats to their health status and it is prudent to manage this anxiety in a timely and expedient manner to prevent escalations. Unfortunately, the medical staff who are likely to spend the most time are usually the most junior who a) lack the experience in identifying potential agitation and b) are unfamiliar with the appropriate pharmacological intervention required. Senior medical staff is often not available due to the demands on their time and expertise. This often means that there is a time delay before appropriate management is instigated and thus in many instances the patient’s behaviour has escalated. At this point simple nonpharmacological strategies for managing aggression will no longer be effective and more advanced management strategies such as sedation will need to be utilised. The increased scope of practice of a Mental Health Nurse Practitioner will enable timely and efficient management utilising the appropriate pharmacological and non-pharmacological management. It would also allow 7 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols for the underlying patient concerns to be addressed and vital decisions relating to ongoing patient management to be addressed much earlier, thus making the use of a Mental Health Nurse Practitioner more judicious and cost effective in terms of the existing human resources who currently are involved in the management of aggression and agitation. The objectives of management will be; • To reduce the patient’s level of agitation and the distress experienced by the patient. • To reduce the potential for harm to the patient or others. • To reduce the potential for damage to property. • To enable appropriate medical / mental health treatment to be administered. 9 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols CLINICAL PROTOCOL 3: THE MANAGEMENT OF AGITATION AND AGGRESSION PROCESS Assessment ACTION 1. May include any or a combination of the following; • Loss of control by the patient which may include any of the following; - Physical assault of others - Forceful damage to property - Forceful injury to others - Injury to self • Body Language - Clenched fists - Clenched jaw - Rigid posture - Tautness indicating intense effort to control emotions - Agitation - Increasing motor activity - Pacing • Hostile threatening verbalisations • Possession of a potential weapon • Provocative behaviour - Argumentative - Dissatisfied - Over-reactive - Hypersensitive - Poor impulse control. REFERENCE Xeniditis et al (2001) LEVEL OF EVIDENCE F Blair (1991) G Fry et al (2002) D 2. Risk assessment for aggression • In collaboration with the treating multi-disciplinary team and other health professionals, exclude underlying causes of aggression eg. Pain, delirium, septicaemia, cerebral pathology, metabolic illness and ensure that organic illness/pathology addressed. • Antecedents and warning signs • Conduct an assessment for imminent aggression using the Broset Violence Checklist National Collaborating Centre for Nursing and Supportive care (2005) Beck et al (1984) G Stuart GW et al (1987) G G Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 10 Treatment Mild – Moderately Arousal Mildly aroused – pacing , still willing to talk reasonably Moderately aroused – agitate, becoming more vocal, unreasonable or hostile Administer (oral therapy) • Option 1 - Diazepam 2-20 mg Or - Clonazepam 0.5 – 2mg Or - Lorazepam 1 – 2.5mg Repeat after 60 minutes if necessary. If ineffective consider Option 2. • • Option 2 - Haloperidol 1.0 – 2.5mg PLUS - Diazepam 5 – 20mg Or - Clonazepam 0.5 - 2.0 mg Or - Lorazepam 1 – 2.5mg Repeat after 60 minutes if necessary. If ineffective consider Option 3 and/or parental route. Option 3 - Olanzapine 2.5 – 5 mg Or - Risperidone 0.5 – 2.0mg SCGH Emergency medical Guidelines (2004) Western Australian Drug & Therapeutics Committee ( 2003) G G Rose et al (2002) Shaw et al (2003) F Marcantonio (2005) E Byrne (2005) F Bateman (2003) Gareri et al (2003) G G Treatment Moderately – Highly Aroused Moderately aroused – agitated becoming more vocal, Administer (Intramuscular Route) • Option 1 - Clonazepam 2 mg Repeat after 30 minutes if necessary • Option 2 - Haloperidol 2.5 mg SCGH Emergency medical Guidelines (2004) Western Australian Drug & Therapeutics G G G Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 11 unreasonable or hostile. Highly Aroused – possibly distressed or fearful, noisy and may include overt violence, unresponsive to or refusing oral medications. – PLUS Clonazepam 2 mg Repeat after 30 minutes if necessary Committee ( 2003) Rose et al (2002) Shaw et al (2003) F Marcantonio (2005) E Byrne (2005) F Bateman (2003) Gareri et al (2003) G G Treatment Highly Aroused Highly aroused – distressed, fearful, noisy and may include overt violence Administer (IMI or IV) • Option 1 - Haloperidol 2.5 – 5 mg SCGH Emergency medical Guidelines (2004) G G WITH OR WITHOUT • Option 2. - Diazepam 2.5 – 10 mg Repeat in 2.5mg doses until adequate sedation is achieved. Western Australian Drug & Therapeutics Committee ( 2003) G Rose et al (2002) Shaw et al (2003) F 12 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols Marcantonio (2005) E Byrne (2005) F Bateman (2003) Gareri et al (2003) G G Precautions associated with the use of suggested medications Precautions should be used with the prescription and use of the suggested medications in the following clinical presentations and / or co-existing physical conditions; • Benzodiazepines (includes diazepine, clonazepine, lorazepine) - History of drug or alcohol abuse / dependence - Myasthenia Gravis - Sleep Apnoea - Severe Respiratory Disease - Severely impaired Liver or renal function - Severe intoxication with alcohol and other CNS depressants • Antipsychotics – Butyrophenones (Haloperidol) - Myocardial infarction within 6 weeks - Tardive dyskinesia - Aggranulocytosis - Neuroleptic Malignant Syndrome (NMS) - Parkinson’s Disease or drugs which antagonise dopamine blocking. • Other antipsychotics (Olanzepine and Risperidone) - Myocardial infarction within 6 weeks - History of tardive dysknesia or NMS - Orthostatic hypotension can occur especially in initial treatment Waddell et al (1996) G G Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 13 General Precautions • • • Elevated proplactin levels Renal impairment (halve dose) Liver impairment (halve dose) Resuscitation and experienced staff need to be available at all times to ensure first-line management in the event of respiratory depression. The patient’s respiratory function needs to be monitored when benzodiazepines are administered. Consideration of the patient’s usual medications which are likely to contribute to the patient’s mental state. SCGH Emergency medical Guidelines (2004) Western Australian Drug & Therapeutics Committee ( 2003) G G Rose et al (2002) Shaw et al (2003) F Marcantonio (2005) E Gareri et al (2003) Ongoing management 1. Once patient’s arousal has subsided provide the patient with the opportunity to discuss / de-brief about incident and attempt to discover the reason for patient’s arousal. This may include utilising skills such as listening skills and negotiation techniques. 2. Ensure that a pre-emptive management plan is in place for subsequent episodes of violence 3. Provide opportunity for staff to ventilate / de-brief post incident National Collaborating Centre for Nursing and Supportive care (2005) F G G 14 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 4. If the management of the underlying cause of the aggression is beyond the scope of practice of the mental health nurse practitioner refer to an appropriate health practitioner (eg psychiatrist, Social worker, patient liaison officer, Complaints office, etc.) 5. For patients being cared for under the provisions of the Mental Health Act, the Office of the Chief psychiatrist must be notified. Mental Health Act (1996) G Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols 15 MANAGEMENT OF AGITATION AND AGGRESSION PATHWAY Assessment of agitated / aggressive patient Mild – Moderate Arousal Option 1(Oral) Diazepam 1-20mg OR Lorazepam 1.0 2.5mg OR Clonazepam 0.5 2.0mg (Repeat after 60 Option 2 (Oral) Haloperidol 1.0 – 2.5mg PLUS Diazepam 5.0 – 20mg OR Lorazepam 1.0 – 2.5mg OR Clonazepam 0.5 – 2.0 mg (Repeat after 60 minutes if necessary) Moderately – Highly Aroused Option 3 (Oral) Risperidone 0.5 – 2.0 mg OR Olanzapine 2.5 – 5mg Option 1 (Intramuscular Route) Clonazepam 2.0mg (Repeat after 30 minutes if necessary) Option 2 (Intramuscular Route) Haloperidol 2.5 mg PLUS OR Clonazepam 2.0 mg (Repeat after 30 minutes if Highly Aroused Option 1 (Intramuscular or Intravenous Route) Haloperidol 2.5 – 5.0,mg WITH OR WITHOUT DIAZEPAM Option 2 (Intramuscular or Intravenous Route) Diazepam 2.5 – 10 mg (Repeat in 2.5 mg doses until adequate sedation achieved) 16 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols DISCHARGE/REFERRAL CRITERIA: Discharge Criteria: • Patients who have completed their treatment with the above techniques • Patients whose psychiatric symptomatology has resolved and which is unlikely to re-occur. Referral Criteria: • Patients whose psychiatric symptomatology is unlikely to respond to the above techniques. • Patients who are displaying no current insight into their condition and are refusing psychiatric treatment. • Patients who require additional treatment or the services of another health professional which is beyond the scope of practice of the Mental Health Nurse practitioner. • Patients who require long-term psychiatric care, psychotherapy or rehabilitation. • Patients under 16 years of age and older than 65 years. The Mental Health Nurse practitioner will facilitate referrals to departments within SCGH and to other mental health services and facilities within the North Metropolitan Health Services. Referrals will be made to the following services; • Other health professionals of the Consultation-Liaison Psychiatric Service at SCGH. • Social Work both within SCGH and other Services within NMHS. • Alcohol and Drug Services within the Hospital and the Alcohol and Drug Services in WA. • Aboriginal Mental Health Service. • Community mental Health Clinics • General practitioners • Private psychiatrists • Private Psychology and Counselling Services • Older-Age Psychiatry (Over 65 years) • Child and Adolescent Psychiatry (Under 16 years). BEST PRACTICE EVIDENCE: The following coding system is used to specify the quality of the supporting evidence for the protocol for mental state assessment: [A] Randomised clinical trial. A study of an intervention in which the subjects are prospectively followed over time; there are treatment and control groups; subjects are randomly assigned to the two groups; both the subjects are the investigators are blind to the assignments. [B] Clinical trial. A prospective study in which an intervention is made and the results of that intervention are tracked longitudinally; study does not meet the standards for a randomised clinical trial. 17 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols [C] Cohort or longitudinal study. A study in which subjects are prospectively followed over time without any specific intervention. [D] Case – control study. A study in which a group of patients and a group of control subjects are identified in the present and information about the subjects is pursued retrospectively or backwards in time. [E] Review with secondary data analysis. A structured analytic review of existing data. Eg. A meta-analysis or a decision analysis. [F] Review. A qualitative review and discussion of previously published literature without a qualitative synthesis of the data. [G] Other. Textbooks, expert opinion, case reports and other reports not included above. REVIEW: This clinical protocol will become effective after approval and will be reviewed every 3 years or more often if significant research / evidence-based information is available which is likely to lead to a change in practice. IMPLEMENTATION PLAN: As the Mental Health assessment of patients is an ongoing process the implementation of this clinical protocol will take place subsequent to the designation of the Mental Health Nurse Practitioner at Sir Charles Gairdner Hospital. The promotion of changes in practice and the enhancement of referrals will be commenced approximately 6 weeks of designation. EVALUATION PLAN: The use of this protocol will be reviewed annually and evaluated using the Clinical Governance framework. Reports will be provided to the crucial key line manager (Nursing Co-Director of Corporate Nursing, Education and research) and the Director General of Health, as part of the process outlined by the Office of the Chief Nursing Officer (Department of Health Western Australia). Clinical Performance and Evaluation: The number of mental health referrals, assessments and disposals (eg. Treated by NP or referred to another health professional) will be monitored over a 12 month period. These statistics will be maintained on a regular basis utilising the PSOLIS database for mental health patients. Professional Development and Management: The Mental Health Nurse Practitioner will be responsible for own individual professional development within the designated area, the provision of education to professional colleagues and own ongoing Performance Management. The development of Policies, Guidelines and standards within the hospital and across the health sector will also be noted. 18 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols Clinical Risk: The identification and minimisation of clinical risks are an important aspect of clinical safety. Practice guidelines and standards and the use of risk assessment tools will be utilised by the Mental Health Nurse Practitioner and probable risks which include clinical incidents and adverse events will be identified and reported as part of the NP review and reporting to the Department of Health. Consumer Value: Consumer Satisfaction will be determined via satisfaction surveys of selected customer groups including selected patients, carers and referring sources. Consumer input into protocols and/or patient information will also be noted. 19 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols DRUG FORMULARY - MENTAL HEALTH Classification Antipsychotic Drug Olazapine Dosage Oral 5.0 – 20 mg / 24 hours Adverse Effects Somnolence Weight Gain Hypotension Anticholergic Effects Antipsychotic Risperidol Oral 6.0 – 8.0 mg / 24 hours Insomnia Agitation Extrapyramidal Effects Anxiety Headache Antipsychotic Haloperidol Oral: 1.0 – 100 mg / 24 hours Extrapyramidal Effects Anticholinergic Effects Dystonic Reactions Akathesia Intramuscular: 2.0 – 10.0 mg initially then further doses given 30 – 60 minutely depending on patient response – should not exceed 100 mg / 24 hours Benzodiazepine Clonazepam Oral / Intramuscular 4.0 – 8.0 mg Benzodiazepine Diazepam Oral / Intramuscular / Intravenous 5.0 – 20 mg Benzodiazepine Lorazepam Oral 2.0 – 4.0 mg Anticholinergic Benztropine Oral / Intramuscular 1.0 – 2.0 mg Dependence CNS depression Anterograde amnesia Disinhibition Intoxication Respiratory depression Dependence CNS depression Anterograde amnesia Disinhibition Intoxication Respiratory depression Dependence CNS depression Anterograde amnesia Disinhibition Intoxication Respiratory depression Anticholinergic Effects, including dry mouth, dilatation of pupils, flushing, worsening of glaucoma, urinary hesitancy, constipation, nausea and blurred vision Central effects including dizziness, hallucinations, euphoria and hyperpyrexia (Therapeutic Guidelines: Psychotropic, 2000; Perry et al, 1997) 20 Sir Charles Gairdner Hospital - Nurse Practitioner Mental Health Clinical Protocols REFERENCES: American Psychiatric Association, (1995) Practice Guidelines for Psychiatric Evaluation of Adults. 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