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Chapter 10 Notes 10–1 Cell Growth A. Limits to Cell Growth 1. DNA “Overload” 2. Exchanging Materials 3. Ratio of Surface Area to Volume 4. Cell Division Ratio of Surface Area to Volume in Cells Cell Size Surface Area (length x width x 6) Volume (length x width x height) Ratio of Surface Area to Volume 10–2 Cell Division A. B. C. D. Chromosomes The Cell Cycle Events of the Cell Cycle Mitosis 1. Prophase 2. Metaphase 3. Anaphase 4. Telophase E. Cytokinesis Objective 1: Summarize the events that occur during mitosis Homologous chromosome--a member of a chromosome pair. similar in shape, size, and the genes they carry. • Chromatid--one of a pair of strands of DNA that make up a chromosome during meiosis or mitosis. Figure 10–4 The Cell Cycle G1 phase M phase S phase G2 phase Interphase This is the non-reproducing stage of a cell’s life. It is the longest stage of a cell’s life Major events in interphase: Cells grow during interphase Chromosomes are duplicated about mid-way through interphase to prepare for mitosis. Interphase Animal Cell Plant Cell Prophase Major events in prophase: Nucleoli disintegrates Chromatin coils up to form chromosomes Centrioles move to opposite poles of the cell Microtubules form spindle fibers between the centrioles The nucleus breaks down Prophase Animal Cell Plant Cell Metaphase Major events in metaphase: Chromosomes attach to the spindle fibers at the centromere Chromosomes move to the equator of the cell Metaphase Animal Cell Plant Cell Anaphase Major events in anaphase: Centromeres split The two sister chromatids separate and move apart to opposite poles of the cell Anaphase Animal Cell Plant Cell Telophase Major events in telophase: The nucleoli reappear The nucleus reforms Chromosomes uncoil and appear as a mass of chromatin Cytokinesis Major Events: Happens at the same time as telophase In animals: cell membrane pinches in at the center In plants: a cell plate forms at the equator of the cell Daughter cells are formed Telophase & Cytokinesis Animal Cell Plant Cell Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Section 10-2 Figure 10–5 Mitosis and Cytokinesis Spindle forming Centrioles Nuclear envelope Chromatin Centromere Centriole Chromosomes (paired chromatids) Interphase Prophase Centriole Cytokinesis Individual Nuclear envelope reforming Go to Section: Spindle Telophase chromosomes Anaphase Metaphase Meiosis Meiosis--a form of cell division that halves the number of chromosomes when forming reproductive cells. Mitosis vs. Meiosis 2n 2n 2n 1n 2n 1n 1n 1n 1n 1n Meiosis I • Prophase I – Chromosomes become visible – Nuclear envelope breaks down – Crossing-over occurs • Metaphase I – Pairs of homologous chromosomes move to the equator of the cell Meiosis I • Anaphase I – Homologous chromosomes move to opposite poles of the cell • Telophase I and Cytokinesis – Chromosomes gather at the poles of the cell – Cytoplasm divides Meiosis II • Prophase II – A new spindle forms around the chromosomes • Metaphase II – Chromosomes line up at the equator Meiosis II • Anaphase II – Centromeres divide – Chromatids (now called chromosomes) move to opposite poles of the cell. • Telophase II and Cytokinesis – Nuclear envelope forms around each set of chromosomes – Cytoplasm divides Bivalent Centromere Chiasma (site of crossing-over) Mitosis vs. Meiosis Close-up View Prophase I Meiosis Bivalents align at the metaphase plate Prophase Mitosis 2n = 4 Chromosomes align at the metaphase plate Metaphase I Sister chromatids remain together during anaphase I X X N X X N N Sister chromatids separate during anaphase x xx x Metaphase Daughter Cells of meiosis I No further chromosomal replication; sister chromatids separate during anaphase II N Daughter Cells of meiosis II 2N 2N Daughter Cells Objective 2: Relate crossing-over, independent assortment, and random fertilization to genetic variation. Independent assortment--the random distribution of homologous chromosomes. Crossing-over--the exchange of reciprocal segments of DNA by homologous chromosomes at the beginning of meiosis. Fertilization is the random joining of 2 gametes. Objective 3: Compare the formation of gametes in male & female animals Spermatogenesis--the process by which sperm are produced in male animals. Occurs in the testes Oogenesis--the process by which gametes are produced in female animals. Occurs in the ovaries Gamete Development Diploid germ cell Diploid germ cell Spermatogenesis Oogenesis Sperm cell Egg cell Polar bodies Meiosis in male & female animals Sperm Formation Egg Formation Diploid germ cell Meiosis I Immature sperm cells Secondary egg cell First polar body Undifferentiated egg cell Meiosis II Undifferentiated sperm cells Sperm Second polar bodies (all 3 will die) Egg cell (ovum) Objective 4: Differentiate between asexual and sexual reproduction asexual reproduction--a single parent passes copies of all of its genes to each of its offspring There is no fusion of haploid cells The offspring is a clone of its parent sexual reproduction--two parents each form haploid reproductive cells, which join to form offspring. Objective 5: Identify three types of asexual reproduction Fission--separation of a parent into two or more individuals of about equal size. Fragmentation--the body of an organism breaks into several pieces. fragments develop into adults when missing parts are regrown Budding--new individuals split off from existing ones. Objective 6: Evaluate the advantages and disadvantages of asexual and sexual reproduction Asexual Reproduction Advantages produce many offspring in short period of time don’t waste energy making gametes or looking for a mate Disadvantages little genetic variation between individuals Sexual Reproduction Advantages quickly produce different combinations of genes among individuals Disadvantages produce fewer offspring in longer periods of time waste energy making gametes & looking for a mate