* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Collaborative and Nursing Management
		                    
		                    
								Survey							
                            
		                
		                
                            
                            
								Document related concepts							
                        
                        
                    
						
						
							Transcript						
					
					Coronary Artery Disease and Acute Coronary Syndrome Chapter 34 Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Leading Causes of Death Copyright © 2014 by Mosby, an imprint of Elsevier Inc. 2 Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Coronary Artery Disease (CAD) • Atherosclerosis  Begins as soft deposits of fat that harden with age  Referred to as “hardening of arteries”  Atheromas (fatty deposits) prefer coronary arteries  Also known as ASHD, CVHD, IHD, CHD Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Coronary Artery Disease Etiology and Pathophysiology • Atherosclerosis is the major cause of CAD  Characterized by lipid deposits within intima of artery  Endothelial injury and inflammation play a major role in development Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Stages of Atherosclerosis Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Coronary Artery Disease Etiology and Pathophysiology • C-reactive protein (CRP)  Nonspecific marker of inflammation  Increased in many patients with CAD  Chronic exposure to CRP associated with unstable plaques and oxidation of LDL cholesterol Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Coronary Artery Disease Etiology and Pathophysiology • Collateral circulation  Arterial anastomoses (or connections) within the coronary circulation  Increased with chronic ischemia  May be inadequate with rapid-onset CAD Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Vessel Occlusion With Collateral Circulation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • M. P. is a 58-year-old white male who visits the local health clinic for a physical examination. • He tells the health care provider that he occasionally gets “indigestion” when he mows the lawn. • It goes away in 5-10 minutes after he stops and rests. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Nonmodifiable risk factors  Age  Gender  Ethnicity  Family history  Genetic predisposition Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Modifiable risk factors  Elevated serum lipids • Cholesterol >200 mg/dL (5.2 mmol/L) • Triglycerides >150 mg/dL (3.7 mmol/L) • High-density lipoproteins (HDL) • Low-density lipoproteins (LDL) • Treatment according to guidelines based on 10-year risk score Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Modifiable risk factors  Hypertension • >140/90 mm Hg or >130/80 mm Hg if diabetes or CKD • Begin lifestyle changes for prehypertension • Treat stage 1 or 2 hypertension with drugs Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Modifiable risk factors  Tobacco use • Increased catecholamine release • ↑ LDL, ↓ HDL, ↑oxygen radicals • ↑ Carbon monoxide  Second-hand smoke Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Modifiable risk factors  Physical inactivity  Obesity  Diabetes  Metabolic syndrome Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Risk Factors for CAD • Modifiable risk factors  Psychologic states  Homocysteine level  Substance abuse Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question Two risk factors for coronary artery disease that increase the workload of the heart and increase myocardial oxygen demand are a. b. c. d. Obesity and smokeless tobacco use. Hypertension and cigarette smoking. Elevated serum lipids and diabetes mellitus. Physical inactivity and elevated homocysteine levels. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question Which patient is most at risk for developing coronary artery disease? a. A hypertensive patient who smokes cigarettes b. An overweight patient who uses smokeless tobacco c. A patient who has diabetes and uses methamphetamines d. A sedentary patient who has elevated homocysteine levels Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Prevention and early treatment • Identification of people at high risk  Health history, including family history  Presence of cardiovascular symptoms  Environmental patterns: diet, activity  Psychosocial history  Values and beliefs about health and illness Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Manage high-risk persons by controlling modifiable risk factors • Encourage lifestyle changes  Education  Clarify personal values  Set realistic goals Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Physical fitness  FITT formula: 30 minutes most days plus weight training 2 days a week  Regular physical activity contributes to • Weight reduction • Reduction of >10% in systolic BP • In some men more than women, increase in HDL cholesterol Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Nutritional therapy  ↓ Saturated fats and cholesterol  ↑ Complex carbohydrates and fiber  ↓ Red meat, egg yolks, whole milk  ↑Omega-3 fatty acids Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question The nurse determines that teaching about implementing dietary changes to decrease the risk of CAD has been effective when the patient says, a. “I should not eat any red meat such as beef, pork, or lamb.” b. “I should have some type of fish at least 3 times a week.” c. “Most of my fat intake should be from olive oil or the oils in nuts.” d. “If I reduce the fat in my diet to about 5% of my calories, I will be much healthier.” Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Lipid-lowering drug therapy   If diet and exercise ineffective Statins • Inhibit cholesterol synthesis, decrease LDL, increase HDL • Monitor for liver damage and myopathy  Niacin • Lowers LDL and triglyceride by inhibiting synthesis • Increases HDL • Flushing, pruritus, GI side effects, orthostatic hypotension Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Lipid-lowering drug therapy  Fibric acid derivatives (Lopid) • Decrease triglycerides and increase HDL • GI side effects  Bile acid sequestrants • Increase conversion of cholesterol to bile acids • GI side effects; bind with other drugs  Ezetimibe (Zetia) • Decrease absorption of dietary and biliary cholesterol Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative and Nursing Management: CAD • Antiplatelet therapy  ASA  Clopidogrel (Plavix) Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Gerontologic Considerations CAD • Increased incidence and mortality associated with CAD in older adults • Strategies to reduce risk and treat CAD are effective • Treat hypertension, ↑lipids • Smoking cessation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Gerontologic Considerations CAD • Necessary to modify guidelines for physical activity  Longer warm-up  Longer periods of low-level activity  Longer rest periods  Avoid extremes of temperature  30 minutes most days minimum • Most likely to change when hospitalized or symptomatic Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study M.P.’s health history and physical examination reveals the following risk factors for CAD: Family history of CAD  Smokes 1 pack of cigarettes a day  Sedentary lifestyle  High fat diet  BP 152/94  BMI 30.2 kg/m2  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. iStockphoto/Thinkstock Case Study iStockphoto/Thinkstock • Based on the presence of these risk factors and M.P.’s complaints of “indigestion” associated with activity, what type of angina is M.P. likely experiencing? Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of CAD Angina • Progressive disease • O2 demand > O2 supply → myocardial ischemia • Angina = reversible ischemia • Occurs when arteries are blocked 75% or more • Hypoxic within 10 seconds of occlusion • Viable for 20 minutes Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of CAD Angina • Lack of oxygen and glucose leads to anaerobic metabolism • Lactic acid irritates nerve fibers → pain in cardiac nerves • Referred pain from transmission to the upper thoracic posterior nerve roots Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of CAD Angina Pain • Pressure/ache • Squeezing, heavy, choking, or suffocating sensation • Rarely sharp or stabbing • Indigestion or burning • Various locations Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of CAD Chronic Stable Angina • Intermittent chest pain that occurs over a long period with the same pattern of onset, duration, and intensity of symptoms • 5 to 15 minute duration • ST segment depression and/or Twave inversion • Control with drugs Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Types of Angina • Silent ischemia  Ischemia that occurs in the absence of any subjective symptoms  Associated with diabetic neuropathy  Confirmed by ECG changes Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Types of Angina • Nocturnal angina  Occurs only at night but not necessarily during sleep • Angina decubitus  Chest pain that occurs only while lying down  Relieved by standing or sitting Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Types of Angina • Prinzmetal’s (variant) angina  Occurs at rest usually in response to spasm of major coronary artery  Seen in patients with a history of migraine headaches and Raynaud’s phenomenon  Spasm may occur in the absence of CAD Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Types of Angina • Prinzmetal’s (variant) angina  Occurs at rest due to spasm of a major coronary artery  May occur with or without CAD  Not precipitated by increased demand  Chest pain with marked, transient STsegment elevation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Types of Angina • Microvascular angina  Chest pain occurs in the absence of significant coronary atherosclerosis or coronary spasm  Myocardial ischemia associated with abnormalities of the coronary microcirculation • Coronary microvascular disease (MVD) affects small, distal coronary arteries Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • While awaiting diagnostic testing for M.P., what drug would you expect the health care provider to prescribe for M.P. to use if he develops the “indigestion” pain the next time he mows the lawn? Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Collaborative Care • Goal: ↓ O2 demand and/or ↑ O2 supply • Short-acting nitrates Dilate peripheral and coronary blood vessels  Give sublingually (tablet) or by spray  If no relief in 5 minutes, call EMS; if some relief ,repeat every 5 minutes for maximum 3 doses  Patient teaching  Can use prophylactically  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Collaborative Care • Long-acting nitrates  To reduce angina incidence  Main side effects: headache, orthostatic hypotension  Methods of administration • Oral • Nitroglycerin (NTG) ointment • Transdermal controlled-release NTG Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Collaborative Care • Angiotensin-converting enzyme inhibitors • β-adrenergic blockers • Calcium channel blockers • Sodium current inhibitor  Ranolazine (Ranexa) Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Collaborative Care • Diagnostic studies  Chest x-ray  Laboratory studies  12-lead ECG  Calcium-score screening heart scan  Echocardiogram  Exercise stress test  Pharmacologic nuclear imaging Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • M.P.’s chest x-ray and ECG results are all within normal limits. • His cholesterol and triglyceride levels are also elevated. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • He develops chest pain and STsegment depression during an exercise stress test. • What additional testing would you expect M.P. to undergo at this point? Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Chronic Stable Angina Nursing/Collaborative Management • Cardiac catheterization/coronary angiography  Visualize blockages (diagnostic)  Open blockages (interventional) • Percutaneous coronary intervention (PCI) • Balloon angioplasty • Stent Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Placement of a Coronary Artery Stent Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Pre-PCI and Post-PCI With Stent Placement Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study • M.P. undergoes a cardiac catheterization. • A 90% occlusion of his right coronary artery (RCA) is discovered. • He has a balloon angioplasty and stent placement. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. iStockphoto/Thinkstock Case Study iStockphoto/Thinkstock • Discharge teaching related to CAD and necessary lifestyle changes (diet and exercise) is provided. • He is scheduled for a follow-up with his health care provider. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • Six months later, MP arrives in the emergency department (ED) complaining of severe, immobilizing chest pain radiating down his left arm. • He admits to not following his health care provider’s advice related to diet and exercise. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • He states that he thought the stent opened up his arteries and cured his CAD. • The ED physician suspects ACS. Explain this diagnosis. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Acute Coronary Syndrome Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Acute Coronary Syndrome Etiology and Pathophysiology Deterioration of once stable plague Rupture Platelet aggregation Thrombus • Result  Partial occlusion of coronary artery: UA or NSTEMI  Total occlusion of coronary artery: STEMI Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Unstable Angina • New in onset • Occurs at rest • Worsening pattern • Increase in frequency • Unpredictable • Medical emergency • Symptoms in women may be more vague Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction (MI) • Result of sustained ischemia (>20 minutes), causing irreversible myocardial cell death (necrosis) • 80%-90% secondary to thrombus • Ischemia starts in subendocardium • Necrosis of entire thickness of myocardium takes 4 to 6 hours • Loss of contractile function Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Myocardial Infarction From Occlusion Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Acute Myocardial Infarction Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction • Pain Severe, immobilizing chest pain not relieved by rest, position change, or nitrate administration  Heaviness, pressure, tightness, burning, constriction, crushing  Substernal, retrosternal, epigastric  More common in AM  Atypical in women, elderly  No pain if cardiac neuropathy (diabetes)  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction • Pain  Described as heaviness, constriction, tightness, burning, pressure, or crushing  Common locations: substernal, retrosternal, or epigastric areas; pain may radiate to neck, jaw, arms Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction • Catecholamine release – stimulation of SNS  Release of glycogen  Diaphoresis  Vasoconstriction of peripheral blood vessels  Skin: ashen, clammy, and/or cool to touch Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction • Cardiovascular  Initially, ↑ HR and BP, then ↓ BP (secondary to ↓ in CO)  Crackles  Jugular venous distention  Abnormal heart sounds • S3 or S4 • New murmur Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Clinical Manifestations of ACS Myocardial Infarction • Nausea and vomiting  Reflex stimulation of the vomiting center by severe pain  Vasovagal reflex • Fever  Up to 100.4° F (38° C) in first 24 hours  Systemic inflammatory process caused by myocardial cell death Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Myocardial Infarction Healing Process • Within 24 hours, leukocytes infiltrate the area of cell death • Proteolytic enzymes of neutrophils and macrophages begin to remove necrotic tissue by fourth day → thin wall • Necrotic zone identifiable by ECG changes and nuclear scanning • Collagen matrix laid down Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Myocardial Infarction Healing Process • 10 to 14 days after MI, scar tissue is still weak • Myocardium vulnerable to stress • Monitor patient carefully as activity level increases Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Myocardial Infarction Healing Process • By 6 weeks after MI, scar tissue has replaced necrotic tissue  Area is said to be healed, but less compliant • Ventricular remodeling  Normal myocardium will hypertrophy and dilate in an attempt to compensate for the infarcted muscle Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Complications of Myocardial Infarction • Dysrhythmias  Most common complication  Present in 80% of MI patients  Can be caused by ischemia, electrolyte imbalances, or SNS stimulation  Life-threatening dysrhythmias seen most often with anterior MI, heart failure, or shock Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Complications of Myocardial Infarction • Heart failure  Occurs when the pumping power of the heart has diminished  Can be subtle or severe • Cardiogenic shock  Occurs because of severe LV failure  Requires aggressive management Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Complications of Myocardial Infarction • Papillary muscle dysfunction  Causes mitral valve regurgitation  Aggravates an already compromised LV → rapid clinical deterioration • Ventricular aneurysm  Myocardial wall becomes thinned and bulges out during contraction  Leads to HF, dysrhythmias, and angina Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Complications of Myocardial Infarction • Acute pericarditis An inflammation of visceral and/or parietal pericardium  May result in cardiac tamponade, ↓ LV filling and emptying, heart failure  Chest pain  Pericardial friction rub  ECG changes  Treated with antiinflammatory agents  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Complications of Myocardial Infarction • Dressler syndrome  Pericarditis with effusion and fever that develops 4 to 6 weeks after MI  Pericardial (chest) pain  Pericardial friction rub  Pericardial effusion  Arthralgia  Treated with short-term corticosteroids Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Unstable Angina and MI Diagnostic Studies • Detailed health history • 12-lead ECG  Changes in QRS complex, ST segment, and T wave  Distinguish between STEMI and NSTEMI  Pathologic Q wave Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Serum Cardiac Markers After MI Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Unstable Angina and MI Diagnostic Studies • Coronary angiography • Exercise or pharmacologic stress testing • Echocardiogram Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study • Identify priority interventions for M.P. on his arrival at the ED. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. iStockphoto/Thinkstock Collaborative Care Acute Coronary Syndrome • Initial interventions  12-lead ECG  Semi-fowler’s position  Oxygen  IV access  Nitroglycerin (SL) and ASA (chewable)  Morphine Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • M.P.’s ECG demonstrates significant ST elevation. • What evidence-based intervention would you expect to prepare M.P. to undergo within 90 minutes of arrival to the ED? Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Ongoing monitoring Treat dysrhythmias  Frequent vital sign monitoring  Bed rest/limited activity for 12–24 hours  • UA or NSTEMI Aspirin, heparin, and glycoprotein inhibitor  Coronary angiography with PCI once stable  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • STEMI or NSTEMI with + cardiac markers → reperfusion therapy • Emergent PCI  Treatment of choice for confirmed MI  Goal: 90 minutes from door to catheter laboratory  Balloon angioplasty + drug-eluting stent(s)  Many advantages over CABG Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Thrombolytic therapy  When PCI not available  Stops infarction process by dissolving thrombus  Within 6 hours of onset of symptoms  Ideally within first hour  Given IV  Patient selection critical Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Thrombolytic therapy  Draw blood and start 2–3 IV sites  Complete invasive procedures prior  Administer according to protocol  Monitor closely for signs of bleeding  Assess for signs of reperfusion • Return of ST segment to baseline best marker • IV heparin to prevent reocclusion Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Coronary surgical revascularization Failed medical management  Presence of left main coronary artery or three-vessel disease  Not a candidate for PCI (e.g., lesions are long or difficult to access)  Failed PCI with ongoing chest pain  History of diabetes mellitus  When long-term benefits of CABG are superior to those of PCI  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Coronary surgical revascularization  Coronary artery bypass graft (CABG) surgery • Requires sternotomy and cardiopulmonary bypass (CPB) • Uses arteries and veins for grafts  Minimally invasive direct coronary artery bypass (MIDCAB) • Alternative to traditional CABG Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Cardiopulmonary Bypass From: Frank W. Sellke et al, Sabiston & Spencer Surgery of the Chest, ed 8, 2010, Saunders. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Internal Mammary Artery and Saphenous Vein Grafts Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Radial Artery Graft • The radial artery is another conduit that can be used. • It is a thick muscular artery that is prone to spasm. • Perioperative calcium channel blockers and long-acting nitrates can control the spasms. • Patency rates at 5 years are as high as 84%. There have been no reports of extremity complications (e.g., hand ischemia, wound infection) following the removal of this artery. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Coronary surgical revascularization  Off-pump coronary artery bypass • Sternotomy but no CPB  Robot-assisted surgery  Transmyocardial laser revascularization • Indirect revascularization • High-energy laser creates channels in heart to allow blood flow Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Drug therapy  IV nitroglycerin  Morphine sulfate  β-adrenergic blockers  Angiotensin-converting enzyme inhibitors  Antidysrhythmia drugs  Cholesterol-lowering drugs  Stool softeners Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question A patient is admitted to the coronary care unit following a cardiac arrest and successful cardiopulmonary resuscitation. When reviewing the health care provider’s admission orders, which order should the nurse question? a. Oxygen at 4 L/min per nasal cannula b. Morphine sulfate 2 mg IV every 10 minutes until the pain is relieved c. Tissue plasminogen activator (t-PA) 100 mg IV infused over 3 hours d. IV nitroglycerin at 5 mcg/minute and increase 5 mcg/minute every 3 to 5 minutes Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Collaborative Care Acute Coronary Syndrome • Nutritional therapy  Initially NPO  Progress to • Low salt • Low saturated fat • Low cholesterol Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Types of Fat in Food Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina and ACS • Nursing assessment: subjective data  Health history • CAD/chest pain/angina/ MI • Valve disease • Heart failure/cardiomyopathy, • Hypertension, diabetes, anemia, lung disease, hyperlipidemia Drugs  History of present illness  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina and ACS • Nursing assessment: subjective data Family history  Indigestion/heartburn; nausea/vomiting  Urinary urgency or frequency  Straining at stool  Palpitations, dyspnea, dizziness, weakness  Chest pain  Stress, depression, anger, anxiety  Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina and ACS • Nursing assessment: objective data  Anxious, fearful, restless, distressed  Cool, clammy, pale skin  Tachycardia or bradycardia  Pulsus alternans  Pulse deficit  Dysrhythmias  S3, S4, ↑ or ↓ BP, murmur Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study • • • iStockphoto/Thinkstock M.P. undergoes emergent PCI with additional stent placement, this time to his circumflex artery. He is admitted to the coronary critical care unit. Identify appropriate nursing diagnoses for M.P. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina and ACS • Nursing diagnoses  Decreased cardiac output  Acute pain  Anxiety  Activity intolerance  Ineffective self-health management Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina and ACS • Planning: overall goals  Relief of pain  Preservation of myocardium  Immediate and appropriate treatment  Effective coping with illnessassociated anxiety  Participation in a rehabilitation plan  Reduction of risk factors Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina • Acute intervention  Semi-Fowler’s position  Supplemental oxygen  Assess vital signs  12-lead ECG  Administer a nitrate followed by an opioid analgesic, if needed  Auscultate heart and breath sounds Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Chronic Stable Angina • Ambulatory and home care  Provide reassurance  Patient teaching • CAD and angina • Precipitating factors for angina • Risk factor reduction • Drugs Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Acute intervention • Pain: nitroglycerin, morphine, oxygen • Continuous monitoring • ECG • ST segment • Heart and breath sounds • VS, pulse oximetry, I&O • Rest and comfort • Balance rest and activity • Begin cardiac rehabilitation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Acute intervention  Anxiety reduction • Identify source and alleviate • Patient teaching important  Emotional and behavioral reaction • Maximize patient’s social support systems • Consider open visitation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study • Describe appropriate nursing care of M.P. following his PCI. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. iStockphoto/Thinkstock Nursing Management Acute Coronary Syndrome • Coronary revascularization: PCI  Monitor for recurrent angina  Frequent VS, including cardiac rhythm  Monitor catheter insertion site for bleeding  Neurovascular assessment  Bed rest per institutional policy Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Coronary revascularization: CABG ICU for first 24–36 hours Pulmonary artery catheter Intraarterial line Pleural/mediastinal chest tubes  Continuous ECG  ET tube with mechanical ventilation  Epicardial pacing wires  Urinary catheter  NG tube     Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Complications related to CPB  Bleeding and anemia from damage to RBCs and platelets  Fluid and electrolyte imbalances  Hypothermia as blood is cooled as it passes through the bypass machine  Infections Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • CABG: postoperative nursing care  Assess patient for bleeding  Monitor hemodynamic status  Assess fluid status  Replace electrolytes PRN  Restore temperature  Monitor for atrial fibrillation (which is common) Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • CABG: postoperative nursing care  Surgical site care • Radial artery harvest site • Leg incisions • Chest incision  Pain management  DVT prevention  Pulmonary hygiene  Cognitive dysfunction Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Ambulatory and home care  Cardiac rehabilitation  Patient and caregiver teaching  Physical activity • METs or Borg Scale • Monitor heart rate • Low-level stress test before discharge • Isometric versus isotonic activities Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • When discussing activity restrictions and expectations after discharge with M.P., he assumes his sex life is now over as he does not want to die having sex with his wife. • How will you respond? Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Ambulatory and home care  Resumption of sexual activity • Teach when discuss other physical activity • Erectile dysfunction drugs contraindicated with nitrates • Prophylactic nitrates before sexual activity • When to avoid sex • Typically 7–10 days post MI or when patient can climb two flights of stairs Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Nursing Management Acute Coronary Syndrome • Evaluation  Stable vital signs  Relief of pain  Decreased anxiety  Realistic program of activity  Effective management of therapeutic regimen Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Sudden Cardiac Death (SCD) • Unexpected death from cardiac causes • Abrupt disruption in cardiac function, resulting in loss of CO and cerebral blood flow • Most commonly caused by ventricular dysrhythmias • Structural heart disease • Conduction disturbances Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Sudden Cardiac Death (SCD) • No warning signs or symptoms if no MI • Prodromal symptoms if associated with MI  Chest pain, palpitations, dyspnea  Death usually within 1 hour of onset of acute symptoms Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Sudden Cardiac Death Nursing/Collaborative Management • Diagnostic workup to rule out or confirm MI  Cardiac markers  ECGs  Treat accordingly • Cardiac catheterization • PCI or CABG Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Sudden Cardiac Death Nursing/Collaborative Management • 24-hour Holter monitoring • Exercise stress testing • Signal-averaged ECG • Electrophysiologic study (EPS) • Implantable cardioverterdefibrillator (ICD) • Antidysrhythmic drugs Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Sudden Cardiac Death Nursing/Collaborative Management • Patient teaching • Psychosocial adaptation  “Brush with death”  “Time bomb” mentality  Additional issues • Driving restrictions • Role reversal • Change in occupation Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question The most significant factor in long-term survival of a patient with sudden cardiac death is a. Absence of underlying heart disease. b. Rapid institution of emergency services and procedures. c. Performance of perfect technique in resuscitation procedures. d. Maintenance of 50% of normal cardiac output during resuscitation efforts. Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Audience Response Question The nurse is caring for a patient who survived a sudden cardiac death. What should the nurse include in the discharge instructions? a. “Because you responded well to CPR, you will not need an implanted defibrillator.” b. “Your family members should learn how to perform CPR and practice these skills regularly.” c. “The most common way to prevent another arrest is to take your prescribed drugs.” d. “Since there was no evidence of a heart attack, you do not need to worry about another episode.” Copyright © 2014 by Mosby, an imprint of Elsevier Inc. Case Study iStockphoto/Thinkstock • What diagnostic testing would you expect the health care provider to order for M.P. ? Copyright © 2014 by Mosby, an imprint of Elsevier Inc.