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Trace minerals Copper • Important component of many metabolic reactions • Found in a variety of foods -seafood like oyster, lobster and crab. • Plant sources include kale and avocado. • It’s also available in nuts, seeds and mushrooms • Recommended dietary allowance is 2 mg/day • Deficiency causes anaemia, leukopenia, osteoporosis • Toxicity not very common but very high amount leads to liver damage Iodine • The main role of the trace mineral iodine is promoting healthy thyroid function. • It helps the body synthesize thyroid hormones that regulate growth and metabolism. • Too much or too little iodine can lead to the conditions known as hyperthyroidism and hypothyroidism. Food Sources: • Seafood as well as seaweed is the best source of iodine. • It is also found in potatoes, eggs and milk. Deficiency : • Goitre in adults • Cretinism in new born RDA : 150µg/day Problems due to excess intake of iodine Hyperthyroidism • Excessive iodine, the iodine interferes with the manufacture of thyroid hormones resulting in low thyroid hormone levels, or hypothyroidism. • Symptoms of hypothyroidism include fatigue, weight gain, dry skin and intolerance to changes in temperature. • Too much iodine also causes other thyroid diseases including Hashimoto’s disease, Graves’ disease and thyroid cancer Problems due to deficiency of iodine • Iodine deficiency is a lack of the trace element iodine. • It may result in goiter (so-called endemic goiter), as well as cretinism in children which results in developmental delays and other health problems • Thus, iodine deficiency can lead to enlargement of thyroid gland, hypothyroidism and mental retardation in infants and children whose mothers were iodine deficient during pregnancy. Goiter Cretinism Selenium • Plays an important role in the protection of body tissues against oxidative stress and also growth & development Food Sources: • Found in most cereals, meats, fish and dairy, legumes and Brazil nuts, as well as fruits and vegetables • RDA : 40 μg/day Problems due to deficiency of selenium • Selenium deficiency is very rare • Selenium deficiency can cause Keshan disease (a type of heart disease) and male infertility. • It might also cause Kashin-Beck disease, a type of arthritis that produces pain, swelling, and loss of motion in the joints. Manganese • Manganese supports enzyme functions as co-enzymes • Found in grains, nuts, legumes, green leafy vegetables • Excess intake causes poor growth, joint inflammation etc • Low levels of manganese in the body can result in impaired glucose tolerance, altered carbohydrate and fat metabolism, skeletal abnormalities, malformation, • RDA – very low bone demineralization and Chromium • Improves insulin action • Found in broccoli, Brewer’s yeast, molasses, barley oats and meat • Deficiency causes glucose intolerance • Too much chromium from supplements can also damage the liver, kidneys, and nerves, and it may cause irregular heart rhythm. Fluoride • Provides strength to bones and teeth, improves resistance tooth enamel • Found in water, seaweed, tea, seafood • Deficiency may cause dental caries • Excess may cause dental and skeletal fluorosis • RDA : about 1 PPM Dental fluorosis Skeletal fluorosis Molybdenum • Cofactor for several enzymes • Found in milk, cheese, beans, legumes, dark green leafy vegetables, cereals and nuts • Effects of deficiency and excess very rare • RDA – very low