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BCNH SFC Learning Outcomes (15-16) Science Foundation Course Learning Outcomes On successful completion of the course, students will be able to: Use ideas about chemical and biological building blocks and apply these concepts to explaining phenomena occurring within biological systems. Indicative Content across the 4.5 weekends CHEMISTRY - Weekend 1 - Day 1 1. Constituents of Matter Defining the three states of matter (solids liquids and gases) and identifying their unique properties. Understanding the physical changes that occur during transitions between states of matter Definition of homogenous and heterogenous mixtures as distinguished from compounds and description of techniques to separate mixtures Description of elements and compounds, atoms and molecules and their relationship to one another Features of atomic structure: a) Sub-atomic particles- protons, neutrons and electrons b) Ions c) Isotopes d) Mass Number e) Atomic Number f) Relative Atomic Mass g) Electronic Configuration- arrangement of shells and subshells in terms of orbitals (s, p, d, f), filling of 2. System International a) SI units of measurement b) Scientific Notation c) Order of Magnitude d) SI units CHEMISTRY - Weekend 1 - Day 2 1. Periodic table a) Understanding the patterns of arrangement of elements into groups and periods b) Patterns of reactivity within groups c) Valency within groups d) Electronic configuration and across periods 1 © BCNH 2005-2016, last updated by BG & SX 20 07 16 BCNH SFC Learning Outcomes (15-16) e) Atom size within groups and periods 2. Compound Formation a) Understanding and explaining the role of the outer shell electron in chemical bonding and intramolecular forces: b) Features of ionic Bonding- metal and non-metals; full transfer of electrons c) Features of covalent bonding- two non-metals; sharing of electrons d) Dative Bonding- electron pair contributed by one atom and shared by two e) Lewis Dot diagrams f) Representing chemical reactions through writing word and balanced symbol equations CHEMISTRY - Weekend 2 - Day 1 1. Acids and Alkalis a) Definition of acids as proton donors and alkalis ad proton acceptors and hydroxide group releasers b) Testing for acids using Indicators c) Measuring acidity and alkalinity using pH 2. Chemical Reactions a) b) c) d) Movement of electrons Bond breaking Reaction mechanisms Homolytic vs Heterolytic cleavage CHEMISTRY - Weekend 2 - Day 2 1. Introduction to Oxidation and Reduction a) Definition of oxidation as loss of electrons and reduction as gain of electrons (redox reactions) b) Explanation of the differences between an oxidising and reducing agents c) Biological examples of redox reactions d) Understanding oxidation numbers 2. Intermolecular Forces a) b) c) d) Hydrophobic forces Permanent dipole interactions Hydrogen bonds Ionic interactions ORGANIC CHEMISTRY - Weekend 3 - Day 1 1. Introduction to Free Radicals a) Understanding that free radicals form as a result of homolytic cleavage b) Naming and writing the formulas of some free radicals c) Describing the key stages of free radical formation- Initiation, Propagation and Termination d) Explanation how antioxidants inhibit propagation 2 © BCNH 2005-2016, last updated by BG & SX 20 07 16 BCNH SFC Learning Outcomes (15-16) 2. Organic Chemistry and Functional Groups a) Description of the features of Alkanes, Alkenes and Alkynes ORGANIC CHEMISTRY - Weekend 3 - Day 2 1. Organic Chemistry and Functional Groups a) b) c) d) e) Rules of Nomenclature of organic molecules Alcohols, Ethers & Carbonyls Carboxylic Acids, Esters & Nitrogen-Based Groups Amides, Thiols & Aromatic Compounds Isomers - Structural and Stereoisomers (enantiomers) (background info only) INTRO TO BIOCHEMISTRY - Weekend 4 - Day 1 1. Introduction to Amino Acids and Proteins a) b) c) d) e) Role of protein within the body Composition and generalised structure of amino acid Essential and Non-essential Amino acids Trans fatty acids and their implications for health Primary, Secondary, Tertiary and Quaternary structure of proteins 2. Enzymes and Catalysts a) Role in lowering activation for increasing reaction rate b) Effect of temperature and pH on enzymatic function c) Enzyme Action: active site, substrate, co-enzymes, co-factors, inhibitors 3. Introduction to Carbohydrates a) b) c) d) e) f) g) Composition of carbohydrates Classification of carbohydrates Monosaccharides, Disaccharides and Polysaccharides Aldoses, Ketose, Hexoses and Trioses Enantiomers Ring formation Presence of carbohydrates within biological systems 4. Introduction to Lipids a) b) c) d) e) Composition of lipids Classification of lipids Cis /Trans fats Essential fatty acids Simple / Complex lipids CYTOLOGY - Weekend 4 - Day 2 1. Cell Structure a. Structure of Animals and Plant cells b. Prokaryote vs eukaryote cells c. Organelles, cell wall, plasma membrane, nucleus, mitochondria, golgi apparatus, endoplasmic reticulum, ribosomes, lysosomes, chloroplasts, cilia 3 © BCNH 2005-2016, last updated by BG & SX 20 07 16 BCNH SFC Learning Outcomes (15-16) d. e. f. g. h. Structure of Nucleic acids Composition of nucleic acids- DNA, RNA, mRNA tRNA Role of nucleic acids DNA replication Purpose of Mitosis/Meiosis and outline the stages within these 2. Transport across plasma membrane a) b) c) d) e) f) Diffusion Osmosis Facilitated Diffusion Active Endocytosis Exocytosis BIOCHEMISTRY - Weekend 5 - Day 1 1. Introduction to Respiration a) Respiration equation: C6H6O6 + 6O CO2 + H2O + 32ATP b) Stages within respiration; Glycolysis, Link Reaction, Kreb’s Cycle and Oxidative Phosphorylation 2. Chemistry of Supplements a) Definition b) Elemental Composition of vitamins and minerals c) Supplement examples and labelling 3. Acids/Alkalis a) The role of buffers in maintaining pH within a narrow range b) Haemoglobin as buffer Weekend 6 - Day 1 a) Revision of materials covered to date Weekend 6 - Day 2 a) Mock Exam b) Mock Exam autopsy 4 © BCNH 2005-2016, last updated by BG & SX 20 07 16