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CURRICULUM VITAE
Laura S. Redwine, Ph.D.
University of California, San Diego
VA Medical Center (9-151)
3350 La Jolla Village Dr.
San Diego, CA 92161
(858) 552-8585 ext. 5359
(619) 543-3447
[email protected]
Education:
Undergraduate:
Graduate:
University of Miami
Coral Gables, FL
Bachelor of Science - 1987
Majors: Biology and Psychology
Uniformed Services University of the Health Sciences
Department of Medical Psychology
Doctor of Philosophy - 1994
Research Experience
2009-Present University of California, San Diego- Assistant Professor
Departments of Psychiatry
San Diego, CA
2001-2009
University of California, San Diego – Assistant Project Scientist
Departments of Psychiatry and Medicine
Veterans Medical Research Foundation
San Diego, CA
9/98 – 08/01 NIH T-32 Clinical Psychopharmacology and Biopsychology Fellow
Department of Psychiatry
University of California, San Diego, CA
8/96 - 8/98
Georgetown University Medical Center - Postdoctoral Fellow
Department of Pharmacology/Physiology
Washington, DC
1/95-7/96
National Institute of Health - Postdoctoral Fellow
Department of Neuropharmacology, Laboratory of Clinical Sciences Branch
Bethesda, Maryland
Teaching Experience
2005 - 2007
Adjunct Professor, Mt. San Jacinto College, Manifee, CA: courses taught: Introduction to
Psychology, and Life Span: Developmental Psychology
2010-2012
Facilitator of Behavioral Cardiology and Psychoneuroimmunology Journal Club
2012-Present Facilitator of Center for Integrative Medicine Journal Club
2011-Present First year Medical School Lecturer on Psychoneuroimmunology and Integrative Medicine
Mentoring
1999-Present Supervised undergraduate and graduate students and post-doctoral trainees
Awards, Honors:
1999 Psychoneuroimmunology Research Society Scholars Award
1999 Fellowship award to explore alternative therapies, Office of the Dean, Medicine, UCSD
2000 NARSAD young investigator award
2001 Psychoneuroimmunology Research Society Scholars Award
2002 American Psychosomatic Society citation poster
2003 American Psychosomatic Society Scholars Award
2004
2008
American Psychosomatic Society citation poster
American Psychosomatic Society citation poster
Professional Activities
2000
Committee member, Fellowships to Explore Alternative Therapies, Univ of California,
San Diego
2004-2009
Manuscript reviews: Journal of Psychosomatic Medicine, Brain Behavior and Immunity,
Annals of Behavioral Medicine, Clinical Gerontologist, Journal of Psychosomatic Research,
Journal of American College of Cardiology, Journal of Alternative and Complementary
Medicine, Journal of Nursing Research, Health Psychology
2006-Present Abstract reviews: Society of Behavioral Medicine and American Psychosomatic Society
2012
Co-Chair: Center for Integrative Medicine Research Development Committee
2011-Present Grant reviewer for NIH, NCCAM
2011-Present Grant reviewer for VA Clinical Science Research and Development
Professional Organizations:
American Psychosomatics Society
Society of Behavioral Medicine
Psychoneuroimmology Research Society
International Society of Behavioral Medicine
Research support ongoing and completed
Laura Redwine, Ph.D. (PI)
9/01/12 – 8/31/14
The John Templeton Foundation
Expanding the Science and Practice of Gratitude
Goal: To examine the relationship between trait gratitude and progression of pre- heart failure and to explore
whether an intervention using gratitude journaling improves psychological and cardiovascular function in
pre- heart failure patients.
Laura Redwine, Ph.D. (PI)
9/15/10 – 6/01/14
National Institutes of Health
NHLBI, R01
Exploring Tai Chi in Heart Failure Patients
Comparison of Tai Chi training, standard exercise and health education in congestive heart failure patients
on mood, health related quality of life, heart failure severity and physical function.
12/01/2010–11/30/2015
Paul Mills, Ph.D. (P.I.)
Laura Redwine, Ph.D. (Co-I)
NIH/NHLBI 2 R01 HL07355-06
BNP and Neuroimmune Characteristics of CHF and Depression
Goal: To examine the effects of depression and heart failure on neuroimmune activation and
clinical outcomes.
Julie Wetherell, Ph.D. (P.I.)
05/2009- 04/2012
Laura Redwine, Ph.D. (Co-I)
Telehealth Therapy for Chronic Pain.
DOD W81XWH-08-PRMRP-CTA
Intervention to Increase Acceptance and Commitment in chronic pain patients
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Laura Redwine, Ph.D. (PI)
9/15/05 – 9/14/08
National Institutes of Health
NCCAM, R21 AT001910-01 A2
Tai Chi: Well-Being and Heart Failure
Comparison of Tai Chi training, standard exercise and health education in congestive heart failure patients
on mood, health related quality of life, heart failure severity and physical function.
Paul Mills, Ph.D. (PI)
02/01/2006 - 1/31/2011
Laura Redwine, Ph.D. (Co-I)
NIH: National Heart, Lung and Blood: 2 R01 HL057265-08A1
Sympathetic Nervous System Regulation of Cell Adhesion in hypertension
Paul Mills, Ph.D. (PI)
Laura Redwine, Ph.D. (Co-I)
NIH/NHLBI, RO1 HL073355-01
05/01/05 - 4/30/10
BNP and Neuroimmune Characteristics of CHF and Depression
Goal: To examine the effects of depression and heart failure on neuroimmune activation and
clinical outcomes.
Thomas Meeks, M.D. (PI)
Laura Redwine, Ph.D. (Co-I)
9/2008-8/2009
Stein Institute for Research on Aging
Tai Chi for Subsyndromal Depression in Older Adults
Bormann, Jill, E. (PI)
Laura Redwine (Co-I)
11/01/02 – 10/31/04
National Institutes of Health, NCAM
Examination of the use of mantra as a relaxation/meditation technique in HIV+ individuals.
Laura Redwine, Ph.D. (PI)
2002-2003
NIH, NIA
Aging, CRH stress pathways and atherogenic processes
Laura Redwine, PhD (PI)
2000– 2002
National Alliance for Research on Schizophrenia and Depression
Depression and congestive heart failure: sympathetic and immune mechanisms
Laura Redwine, PhD (PI)
1999-2001
Fellowship Award to Explore Alternative Therapies, UCSD
Meditation: A behavioral intervention for psychological stress in African Americans
Published Manuscripts
Rutledge T, Redwine LS, Linke SE, Mills PJ. A meta-analysis of mental health treatments and cardiac
rehabilitation for improving clinical outcomes and depression among patients with coronary heart
disease. (2013) Psychosom Med.75(4):335-49.
Wentworth BA, Stein MB, Redwine LS, Xue Y, Taub PR, Clopton P, Nayak KR, Maisel AS. Posttraumatic Stress Disorder: A Fast Track to Premature Cardiovascular Disease? (2013 ) Cardiol Rev.
21(1):16-22.
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Redwine, LS, Tsuang, M, Rusiewicz, A, Pandzic, I., Cammarata, S., Rutledge, T, Hong, S, Linke, S and
Mills, PJ. (2012) A pilot study exploring the effects of a twelve-week Tai chi intervention on
somatic symptoms of depression in heart failure patients. Journal of Alternative and Complementary
Medicine, 18(8):744-8.
Wilson KL, Tomfohr L, Edwards K, Knott C, Hong S, Redwine L, Calfas K, Rock CL,von Känel R, Mills
PJ. (2012) Effects of aerobic fitness and adiposity on coagulation biomarkers in men vs. women
with elevated blood pressure. European Journal of Cardiovascular Medicine, 11(11): 112-128.
Xue Y, Taub PR, Iqbal N, Fard A, Wentworth B, Redwine L, Clopton P, Stein M, Maisel A. Cardiac
biomarkers, mortality, and post-traumatic stress disorder in military veterans.Am J Cardiol. 2012
Apr 15;109(8):1215-8.
Covassin, N., Neikrug, A. B., Liu, L., Maglione, J. E., Natajaran, L., Corey-Bloom, J., Loredo, JS, Palmer,
BW, Redwine, LS, and Ancoli-Israel,S (2012). Relationships between clinical characteristics and
nocturnal cardiac autonomic activity in Parkinson's disease. Autonomic Neuroscience: Basic and
Clniical, (in press).
Redwine, LS, Wirtz, PH, Hong, S., Bosch, J., Ziegler, M., Greenberg, B. and Mills, PJ. (2010) Depression
as a potential modulator of β-adrenergic -associated leukocyte mobilization in heart failure patients.
Journal of the American College of Cardiology, 56(21):1720-7. PMCID: PMC2999627
Wirtz PH, Redwine LS, Hong S, Rutledge T, Dimsdale JE, Greenberg BH, Mills PJ. (2010) Increases in Btype natriuretic peptide after acute mental stress in heart failure patients are associated with alcohol
consumption. J Stud Alcohol Drugs 71(5):786-94. PMCID: PMC2930511 [Available on 2011/9/1]
Wirtz, PH, Redwine, LS, Hong, S, Linke, S., Rutledge, T, Greenberg, B, Mills, PJ. (2010). Circulating
levels of soluble intercellular adhesion molecule-1 (sICAM-1) independently predict depressive
symptom severity after 12 months in heart failure patients. Brain, Behavior and Immunity
24(3):366-9.
Wirtz PH, Redwine LS. (2010). Commentary on hostility and physiological responses to laboratory stress in
acute coronary syndrome patients. J Psychosom Res.68(2):117-9.
Wirtz, PH, Ehlert, U., Bartschi, C., Redwine, L.S., von Kanel, R. (2009). Changes in plasma lipids with
psychosocial stress are related to hypertension status and the norepinephrine stress response.
Metabolism Clinical and Experimental 58, 30–37.
Redwine, LS, Wirtz, PH, Hong, S, Pandzic, I, Cammarata, S, Tafur, J, Carter, SM, Greenberg, B, Mills, PJ
(2009). A potential shift from adaptive immune activity to non-specific inflammatory activation
associated with higher depression symptoms in congestive heart failure patients. Journal of Cardiac
Failure, 15(7):607-15.
Bormann, J. E., Aschbacher, K., Wetherell, J. L., Roesch, S., & Redwine, L. (2009). Effects of
faith/assurance on cortisol levels are enhanced by a spiritual mantram intervention in adults with
HIV: A randomized trial. Journal of Psychosomatic Research, 66(2), 161-171.
Wirtz, PH, Hong, S, Redwine, LS, Tafur, J, Rutledge, T, Ziegler, MG, Greenberg, B, Mills, PJ. (2009).
Depressive symptoms are associated with soluble P-selectin (sP-selectin) reactivity to acute
exercise in heart failure. Biological Psychiatry, 65(9):801-7
Wirtz PH, Redwine LS, Baertschi C, Spillmann M, Ehlert U, von Känel R. (2008). Coagulation activity
before and after acute psychosocial stress increases with age. Psychosom Med. 70(4):476-81.
Daniels LB, Allison MA, Clopton P, Redwine L, Siecke N, Taylor K, Fitzgerald R, Bracker M, Maisel AS.
(2008). Use of natriuretic peptides in pre-participation screening of college athletes. Int J Cardiol. Mar
14;124(3):411-4.
Mills, PJ, Dimsdale, JE, Hong, S, Van Den Brande, G, Redwine, LS, Greenberg, BH, and Rutledge, T. (2008)
Brief report: Characteristics of antidepressant use in patients with heart failure Patient Preference and
Adherence 2, 333–336. PMC2770413
Meeks, T, Wetherell , J, Irwin , M, Redwine , L, Jeste, D. (2007) Complementary and Alternative
Treatments for Late-life Depression, Anxiety, and Sleep Disturbance: A Review of Randomized
Controlled Trials, J of Clinical Psychiatry, 68(10):1461-71.
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Redwine LS, Mills PJ, Hong S, Rutledge T, Reis V, Maisel A, Irwin MR. (2007) Cardiac-related
hospitalization and/or death associated with immune dysregulation and symptoms of depression in
heart failure patients. Psychosomatic Medicine, 69(1):23-9.
Bormann JE, Gifford AL, Shively M, Smith TL, Redwine L, Kelly A, Becker S, Gershwin M, Bone P,
Belding W. (2006) Effects of spiritual mantram repetition on HIV outcomes: a randomized
controlled trial. J Behav Med. 29(4):359-76.
Mills PJ, Hong S, Redwine L, Carter SM, Chiu A, Ziegler MG, Dimsdale JE, Maisel AS. (2006) Physical
fitness attenuates leukocyte-endothelial adhesion in response to acute exercise.
J Appl Physiol. 101(3):785-8
Redwine, LS, Mills, PJ, Sada, M, Dimsdale, J, Patterson, T, & Grant, I. (2004) Differential immune cell
chemotaxis responses to acute psychological stress in Alzheimer caregivers compared to noncaregiver controls. Psychosomatic Medicine, 66, 5, 770-75.
Redwine LS, Dang, M. & Irwin M. (2004) Sleep and nocturnal changes in cellular adhesion molecule
density, Brain, Behavior and Immunity 18(4) 333-340.
Irwin, M, Rinetti, G, Redwine, L, Motivala, S, Dang, J, Ehlers, C. (2004) Nocturnal Proinflammatory
Cytokine-associated sleep disturbances in abstinent African American alcoholics, Brain, Behavior
and Immunity, 18(4) 349-360..
Redwine LS, Mills PJ and Irwin, M. (2003) Acute Psychological Stress: Effects on Chemotaxis and
Cellular Adhesion Molecule Expression. Psychosomatic Medicine , 65, 598-603.
Redwine LS, Hall M, Dang, J. and Irwin M. (2003) Disordered Sleep, Nocturnal Cytokines and Immunity
in Alcoholics Psychosomatic Medicine, 65, 75-85.
Altemus, M., Redwine, L.S., Leong, Y. Porges & Carter, C.S. (2001) Responses to laboratory psychosocial
stress in postpartum women. Psychosomatic Medicine. 63(5):814-21.
Redwine, L.S., Altemus, M., Leong, Y. & Carter, C.S. (2001) Lymphocyte Responses to stress in
postpartum women: relationship to vagal tone, Psychoneuroendocrinology , 26, 241-251.
Redwine, LS, Hauger RL, Gillin JC, Irwin M. (2000) Effects of sleep and sleep deprivation on interleukin6, growth hormone, cortisol and melatonin levels in humans. Journal Clinical Endocrinology and
Metabolism, 85(10) 3597-3603.
Redwine, L.S., Rone, J.D., Pert, C.B., Vance, M., Nixon, R., Sandler, B., Lumpkin, M.D., & Ruff, M.R.
(1999) The effects of gp120 and HIV-1 derived peptide T on RANTES and MIP-1 beta stimulated
monocyte chemotaxis. Clinical Immunology. Nov, 93(2):124-31.
Altemus, M., Redwine, L.S., Leong, Y. & Murphy, D. (1997) Reduced sensitivity to glucocorticoid
feedback and reduced glucocorticoid receptor mRNA expression in the luteal phase of the menstrual
cycle. Neuropsychopharmacology, 17(2):100-9.
Benight, C.C., Antoni, M.H., Killborn, K., Ironson, G., Kumar, M., Fletcher, M., Redwine, L.S., Baum, A.,
Schneiderman, N. (1997) Coping, self efficacy, buffers psychological and physiological
disturbances in HIV infected men following natural disaster. Health Psychology, 16, 248-255.
Redwine, L.S., Baum, A.S. & Jenkins, F.(1996). The effects of stress on adrenoreceptor density and
lymphocyte proliferation in humans. International Journal of Behavioral Medicine,3(4) 337-353
Teich, A.H., McCabe, P.M., Gentile, C.C., Schneiderman, L.S., Winters, R.W.,Liskowsky, D.R. &
Schneiderman, N. (1989). Auditory cortex lesions prevent the extinction of Pavlovian differential
heart rate conditioning to tonal stimuli in rabbits. Brain Research, 480, 210-218.
Book Chapters
1)
Schneiderman, L.S. & Baum, A.S. Acute and chronic stress and the immune system. In N.
Schneiderman, P. McCabe & A.H. Baum (Eds.) Perspectives in Behavioral Medicine: Stress and
Disease Processes. Lawrence Erlbaum Associates, Publishers: Hillsdale, New Jersey (1992).
2)
Jain, S., Hong, S., Redwine, L.S., Mills, P.J. Laboratory Based Measures of the Immune System. In
L. Gallo & L. Luecken (Eds.) Handbook of Physiological Research Methods in Health Psychology.
Sage Publications: New York, New York (2008).
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3)
Redwine, L.S., Greenberg, B. and Mills, P.J. A Behavioral Medicine Approach to the Study of
Heart Failure. In Shari Waldstein, Leslie Katzel, and Willem Kop,(Eds.) Handbook of
Cardiovascular Behavioral Medicine. Springer Publishing, New York (2010).
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