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COURSE SYLLABUS
Academic year: 2013/2014
Description of Subject of Education - Teaching Program
Name of course:
PATHOPHYSIOLOGY
Head of the
Department:
Witold Pilecki
dr hab. prof. nadzw.
Faculty:
Field of study:
Level of study:
Medical
Medicine
Master’s-level, Uniform (single degree)
Form of study:
Year of study:
Full-time
II
Type of course:
Lecturer’s language:
Compulsory
English
Department conducting the subject
Department of Pathophysiology
Semester:
3 and 4
Winter semester (hrs)
L
C
S
10
30
Summer semester (hrs)
L
C
S
10
30
Total number of hours per year: 80
Goals of the course:
G1 – The aim is to present and elucidate in the clear and comprehensive manner the structural and
functional pathomechanisms underlying the most common disorders and diseases affecting the individual
systems and organs of the human body.
Matrix of the education effects for the subject in reference to methods of verification of the effects
intended and to forms of the course (K – knowledge; S – skills)
No. of education effect Description of education effect
Verification methods of Forms of the course **
achieving the intended
education effects*
Student knows and understands oral response, credit test
L, C
K1
the pathophysiological
background of the most
common and crucial diseases
and disorders.
K2
K3
S1
Student knows how to combine
the various symptoms to make
up a diagnosis of the disease.
oral response, credit test
L, C
Student knows how to predict
the complications of the
diseases.
oral response, credit test
L, C
Student is able to recognize and
give an interpretation of the
essential abnormalities of the
discussion
C
electrocardiographic (ECG)
recordings, blood smear,
gasometry, spirometry and
levels of hormons.
* presentation, response, discussion, essay, colloquium, examination (oral, written, test)
** L- lecture; S- seminar; C- class; EL- e-learning
Balance of ECTS points
Activities at the university
Student’s own work
Total student’s workload
ECTS of the course (per year)
80 (40+40) hours
42 (15 + 27) hours
122 (55+67) hours
6.0
DETAILED PROGRAM OF THE COURSE
Winter semester – Lectures (Tutor: M. Sobieszczańska)
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Pathophysiological background of electrocardiography
Modern and experimental electrocardiographic techniques (e.g. BSPM, MCG, SATRO).
Pathomechanisms and risk factors of atherosclerosis; essentials of cardiovascular disease prevention.
Ischemic heart disease – pathogenesis, clinical forms, diagnostics.
Genetically determined heart diseases.
Structures and functioning of the gastrointestinal system.
Peptic ulcer disease (PUD) – etiology, signs, complications.
Jaundice – pathomechanisms and differential diagnosis.
Bronchial asthma – etiology, clinical presentation.
Chronic obstructive pulmonary disease (COPD) – etiology, clinical presentation.
Winter semester – Seminars (M. Sobieszczańska, M. Poręba, A. Biełous, P. Kolęda, M. Tabin)
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Principles of normal ECG analysis
Practicing the normal ECGs interpretation and description
Pathomechanisms and classification of cardiac rhythm disturbances
Reading the ECGs presenting cardiac arrhythmias
Pathomechanisms and classification of heart blocks
Reading the ECGs presenting heart blocks
Acute coronary syndromes and myocardial infarction – pathogenesis and diagnostics
Reading the ECGs presenting various forms of myocardial ischemia and infarct
Heart failure – right and left ventricular; pathomechanisms, clinical signs
Arterial hypertension – causes, symptoms and signs, consequences
Valvular heart disease – pathogenesis, influence over hemodynamics
ECG findings in various clinical states (hypertrophy, electrolytes imbalance, artificial pacemaker)
Credit Test #1 (Cardiology)
Oesophageal achalasia, GERD (gastroesophageal reflux disease)
Inflammatory bowel disease (IBD) – pathogenesis, clinical presentation
Hepatitis – etiology, clinical presentation
Cholelithiasis and cholecystitis – etiology, clinical presentation
Pancreatitis, acute and chronic – etiology, clinical presentation
Acute and chronic respiratory insufficiency – etiology, clinical presentation
Obstructive lung diseases
Restrictve lung diseases
Spirometry examination, parameters, interpretation
Emphysema, pneumothorax, atelectasis, pulmonary oedema
Pulmonary embolism – etiology, clinical presentation, outcome
Credit Test #2 (Alimentary and Respiratory systems)
Summer semester – Lectures (Tutor: M. Sobieszczańska)
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Organization of the endocrine system, neuro-humoral regulation, negative feedback loop.
Endocrine organs – structure and functioning.
Hormones – classification, structure, secretion and molecular functioning.
Pituitary gland – structure, hormones, regulation axis, hypofunction, hyperfunction.
Pathophysiology of the adrenal medulla, stress hormones, pheochromocytoma.
Metabolic syndrome, obesity – definition, epidemiology, clinical relevance.
Diabetes mellitus type 2 as civilization pandemia; definition of cardiodiabetology.
Menopause – pathophysiology, signs, management.
Biochemical disorders in kidney insufficiency.
Genetic background of the blood coagulation disorders.
Summer semester – Seminars (M. Sobieszczańska, M. Poręba, A. Biełous, P. Kolęda, M. Tabin)
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Growth hormone – pathophysiology, dysfunctions: dwarfism, gigantism and acromegaly
Posterior pituitary hormones (ADH and oxytocin) abnormalities
Hyperthyroidism, Graves’ disease – etiology, pathomechanism, symptoms and signs
Hypothyroidism – congenital, acquired; etiopathogenesis, clinical presentation
Calcium-phosphates metabolism; hormonal regulation, rickets
Hypoparathyroidism – causes, clinical signs: hypocalcemia, tetany
Hyperparathyroidism: primary and secondary – causes; hypercalcemia – consequences
Adrenocortical hormones (glucocorticoids, mineralocorticoids, sex hormones) – pathophysiology
Hypercortisolism – Cushing’s syndrome, Cushing’s disease, cushingdoidal syndrome
Hyperaldosteronism – Conn’s syndrome: arterial hypertension, hypopotasemia
Adrenocortical insufficiency – Addison’s disease: etiopathogenesis, clinical presentation
Diabetes mellitus – epidemiology, etiology, pathomechanisms, clinical classification
Diabetes mellitus type 1 – clinical presentation, acute and chronic complications, treatment
Diabetes mellitus type 2 – clinical presentation, acute and chronic complications, pathophysiology of accelerated
atherosclerosis, management (diet, drugs and physical activity)
Hormone secreting pancreatic tumors (insulinoma, glucagonoma, somatostatinoma)
Credit Test # 3 (Endocrinology)
Kidneys structures and functions – review
Urinalysis – normal and pathological components; polyuria, oliguria, anuria; proteinuria, bacteriuria
Acute renal failure – causes, pathomechanisms, clinical presentations, lab tests
Chronic renal failure – causes, pathomechanisms, clinical presentations, lab tests
Nephrotic syndrome – causes , clinical presentation, complications
Glomerulonephritis – etiology, classification, manifestations, diagnostics, complications
Pyelonephritis – etiology, clinical presentation, diagnostics, complications
Renal stones – etiology, clinical presentation, diagnostics, complications
Acid-base equilibrium pathophysiology (renal, lung and blood components), gasometric tests analysis
Acidosis – respiratory / metabolic: causes, signs, compensatory mechanisms
Alkalosis – respiratory / metabolic: causes, signs, compensatory mechanisms
Normal blood composition, blood count, main blood functions.
Thrombophilia (hypercoagulability, prothrombotic state) – predisposing factors, consequences
Pathological bleeding – vascular abnormalities, platelets disorders, coagulation disorders
Platelets disorders: thrombocytopenia, thrombocytosis, thrombocytopathia
Blood coagulations factors pathology: inherited and acquired
Hemophilia A and B – etiopathogenesis, clinical course, outcome, replacement therapy
Anemias – etiopathogenesis, classification, clinical signs, laboratory diagnostics
Leukemias – acute and chronic: etiopathogenesis, classification, signs, diagnostics, prognosis
Credit Test # 4 (Nephrology & Hematology)
Teaching aids:
Laptop, multimedia projector, 12-lead ECG apparatus
Terms for successful completion of course:
Passing four credit exams (tests) and final examination (test).
Name and address of the unit leading the course; contact (tel./email):
Zakład Elektrokardiologii i Prewencji Chorób Sercowo Naczyniowych Katedry Patofizjologii
Tel./fax: 71 784 12 47 E-mail: [email protected]
Person responsible (Examiner) :
Dr hab. Małgorzata Sobieszczańska, prof. nadzw.
The Unit Head’s signature:
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Date:
20.09.2013
Dean’s signature:
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