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JULY 2016 - NEWSLETTER Neosporosis Neosporosis is caused by the protozoan parasite Neospora caninum and the most commonly identified cause of infectious abortion in the UK. Infection in the average UK dairy herd is estimated to cost in the region of £3000 per year. Cattle become infected by one of two routes. Firstly from the ingestion of oocysts (parasite eggs) in the faeces of infected dogs through contaminated feed or water. The parasite then goes through a stage of multiplication in the cow’s bloodstream before infecting cells and forming tissue cysts. The dog becomes infected by eating tissue containing these tissue cysts such as placenta, aborted foetus or meat. “ Secondly cattle can become infected during pregnancy. Calves from infected dams have a 80-90% chance of being born infected. This is thought to be the most common mode of transmission of the disease. There is currently no evidence of adult cow to cow transmission. The most common way of introducing Neospora onto a farm is thought to be buying infected cattle, but infection can also be brought on by dogs. After infection, a dog will shed for only 2-3 weeks but does not usually show any clinical signs. After this period the dog develops immunity and is no longer a threat to cattle. Currently there is no evidence that foxes or any wildlife in the UK have a role in spreading bovine neosporosis, however this is an area of ongoing investigation. Not all cows infected with Neospora will abort but, they are 5 to 7 times more likely to abort than uninfected animals. The outcome of Neospora infection depends on what stage of pregnancy infection of the foetus occurs. In early pregnancy it generally leads to foetal death, in mid-pregnancy infection can cause foetal death or the birth of infected calves sometimes with neurological problems, generally in late pregnancy calves are born infected but otherwise normal. Abortions to Neospora tend to occur around 5-7 months pregnancy. Cases of early foetal death result in reabsorption of the embryo and return to oestrous. ” Diagnosis of Neospora in an abortion is made at post-mortem of the foetus, blood sampling is the only method of diagnosis in the live animal. Though positive blood test in the dam doesn’t confirm Neospora as the cause of abortion only that she is infected. Screening the herd for Neospora can be difficult as antibody levels fluctuate, negative results doesn’t always mean an animal is not infected. Screen cows in mid to late pregnancy gives the best chance of revealing infected animals, such as at drying off. Biosecurity is essential to prevent Neospora being brought into your herd, sourcing cattle from herds tested free and testing animals after arrival is essential. Cows id entified as infected should b bred to e beef to prevent the dise ase est Currently there are no vaccines or treatments for Neospora, control is based around biosecurity, testing and in future g ablishing eneratio ns breeding management. Dogs should be kept away from calving areas and afterbirth, and foetal material or culle d. disposed of quickly. Rodents may act as intermediate hosts passing infection from infected foetal material to the dogs and so robust rodent control is important. Cows identified as infected should be bred to beef to prevent the disease establishing in future generations or culled. After identifying infected animals the dam and any daughter should be tested to establish the extent of infection in that family line. Hypocalcaemia Many herds have now turned cows out to grass, however if not managed well, a poor transition back to milking can lead to high levels of disease in freshly calved cows. Incidence of both clinical and sub-clinical hypocalcaemia can often increase as dry and calving cows are turned out to grass. Often this is restricted purely to a sub-clinical level meaning we don’t see any clinical effects of the low calcium level. Sub-clinical hypocalcaemia if often a gateway disease for other conditions: • 8 times more likely to get mastitis • 3 times more likely to suffer from difficult calvings • Twice as likely to have retained placenta or displaced abomasum • 12 days longer calving to conception • Lower conception rates Periodically testing freshly calved cows calcium levels is important to monitor the prevalence of hypocalcaemia on your farm and assess the need for dietary change or calcium therapy around calving to reduce risk. Any increase in peri-paturient disease should also raise alarm bells to problems with transition cow management and diet. BVD & IBR We recently screened all Oakhill dairy herds for BVD and IBR as part of our monitoring program. 51% of herds were both BVD and IBR vaccinated, of the BVD non-vaccinated herds, 87% were antibody positive, showing exposure to virus and potential for infection to be present in the herd. 11% of the non-vaccinated herds had a positive PCR positive result on the bulk tank indicating active infection and virus circulating in the milking herd. Of the non-vaccinating IBR herds 70% showed exposure to IBR, given IBR infection is lifelong the virus is therefore present in these herds. The results show the importance of monitoring disease status on the farm particularly non-vaccinated herds as exposure to viruses is very common. Bulk tank screening is the easiest way to get an overall view of herd status and indicate if further testing is necessary. Of the non-vaccinated herds 87% were antibody positive. Of the non-vaccinated herds 11% PCR Positive Result 01772 861300 www.redrosedairydiscussiongroup.co.uk